Published in Horm Metab Res on December 01, 1996
The roles of leptin and adiponectin: a novel paradigm in adipocytokine regulation of liver fibrosis and stellate cell biology. Am J Pathol (2005) 1.49
Metabolic syndrome: the danger signal in atherosclerosis. Vasc Health Risk Manag (2006) 1.13
Leptin- and leptin receptor-deficient rodent models: relevance for human type 2 diabetes. Curr Diabetes Rev (2014) 1.12
Sex dimorphism and depot differences in adipose tissue function. Biochim Biophys Acta (2013) 1.10
Contribution of androgens to the gender difference in leptin production in obese children and adolescents. J Clin Invest (1997) 1.08
Adipokines and proinflammatory cytokines, the key mediators in the pathogenesis of nonalcoholic fatty liver disease. World J Gastroenterol (2014) 1.07
Mechanisms of glucocorticoid-induced insulin resistance: focus on adipose tissue function and lipid metabolism. Endocrinol Metab Clin North Am (2014) 1.07
The differential relationship between fat mass and bone mineral density by gender and menopausal status. J Bone Miner Metab (2011) 0.93
Comparative Transcriptome Analysis of Adipose Tissues Reveals that ECM-Receptor Interaction Is Involved in the Depot-Specific Adipogenesis in Cattle. PLoS One (2013) 0.91
Different modulation by dietary restriction of adipokine expression in white adipose tissue sites in the rat. Cardiovasc Diabetol (2009) 0.90
Role of leptin resistance in the development of obesity in older patients. Clin Interv Aging (2013) 0.90
Body composition and cardiovascular risk markers after remission of Cushing's disease: a prospective study using whole-body MRI. J Clin Endocrinol Metab (2012) 0.89
Leptin signaling and Alzheimer's disease. Am J Neurodegener Dis (2012) 0.88
Intra- and interindividual variation in gene expression in human adipose tissue. Pflugers Arch (2006) 0.87
Differences in the association between serum leptin levels and body mass index in black and white women: a report from the Southern Community Cohort Study. Ann Nutr Metab (2012) 0.86
Effects of Gengnianchun on learning and memory ability, neurotransmitter, cytokines, and leptin in ovariectomized rats. Int J Clin Exp Med (2015) 0.80
High ascitic fluid leptin levels in patients with decompensated liver cirrhosis and sterile ascites: relationship with TNF-alpha levels. Dig Dis Sci (2004) 0.79
Site-specific modulation of white adipose tissue lipid metabolism by oleoyl-estrone and/or rosiglitazone in overweight rats. Naunyn Schmiedebergs Arch Pharmacol (2010) 0.77
Changes in Central Aortic Pressure, Endothelial Function and Biomarkers in Hypertensive African-Americans with the Cardiometabolic Syndrome: Comparison of Amlodipine/Olmesartan versus Hydrochlorothiazide/Losartan. Cardiorenal Med (2013) 0.77
Molecular cloning of feline resistin and the expression of resistin, leptin and adiponectin in the adipose tissue of normal and obese cats. J Vet Med Sci (2015) 0.76
Beyond thermoregulation: metabolic function of cetacean blubber in migrating bowhead and beluga whales. J Comp Physiol B (2016) 0.75
Metabolic syndrome: is equine disease comparable to what we know in humans? Endocr Connect (2014) 0.75
A European evidence-based guideline for the prevention of type 2 diabetes. Horm Metab Res (2010) 3.15
Hypothalamic CART is a new anorectic peptide regulated by leptin. Nature (1998) 2.99
Characterization of a human preadipocyte cell strain with high capacity for adipose differentiation. Int J Obes Relat Metab Disord (2001) 2.94
Cloning of a novel family of mammalian GTP-binding proteins (RagA, RagBs, RagB1) with remote similarity to the Ras-related GTPases. J Biol Chem (1995) 2.41
cDNA cloning, tissue distribution, and identification of the catalytic triad of monoglyceride lipase. Evolutionary relationship to esterases, lysophospholipases, and haloperoxidases. J Biol Chem (1997) 2.30
Sequence characteristics, subcellular localization, and substrate specificity of DYRK-related kinases, a novel family of dual specificity protein kinases. J Biol Chem (1998) 2.29
Informatics and medicine--from molecules to populations. Methods Inf Med (2008) 2.13
Specificity determinants of substrate recognition by the protein kinase DYRK1A. J Biol Chem (2000) 2.05
Variation in the HHEX-IDE gene region predisposes to type 2 diabetes in the prospective, population-based EPIC-Potsdam cohort. Diabetologia (2007) 2.02
Dyrk, a dual specificity protein kinase with unique structural features whose activity is dependent on tyrosine residues between subdomains VII and VIII. J Biol Chem (1996) 2.00
Take action to prevent diabetes--the IMAGE toolkit for the prevention of type 2 diabetes in Europe. Horm Metab Res (2010) 1.99
Structural and functional characteristics of Dyrk, a novel subfamily of protein kinases with dual specificity. Prog Nucleic Acid Res Mol Biol (1999) 1.97
Glucocorticoids and insulin promote the differentiation of human adipocyte precursor cells into fat cells. J Clin Endocrinol Metab (1987) 1.78
Human adipocytes secrete mineralocorticoid-releasing factors. Proc Natl Acad Sci U S A (2003) 1.74
The cost burden of diabetes mellitus: the evidence from Germany--the CoDiM study. Diabetologia (2006) 1.69
Effect of BMI and age on adipose tissue cellularity and differentiation capacity in women. Int J Obes Relat Metab Disord (2003) 1.62
Identification of the autophosphorylation sites and characterization of their effects in the protein kinase DYRK1A. Biochem J (2001) 1.61
Treatment of anthracycline extravasation with Savene (dexrazoxane): results from two prospective clinical multicentre studies. Ann Oncol (2006) 1.54
Peripheral monocytes of obese women display increased chemokine receptor expression and migration capacity. J Clin Endocrinol Metab (2014) 1.49
Microscale oxygraphy reveals OXPHOS impairment in MRC mutant cells. Mitochondrion (2012) 1.49
Exon-intron organization and chromosomal localization of the mouse monoglyceride lipase gene. Gene (2001) 1.49
Reduced expression of PSCA, a member of the LY-6 family of cell surface antigens, in bladder, esophagus, and stomach tumors. Biochem Biophys Res Commun (2000) 1.48
Hormone-sensitive lipase and monoacylglycerol lipase are both required for complete degradation of adipocyte triacylglycerol. Biochim Biophys Acta (1986) 1.45
Obesity and impaired fibrinolysis: role of adipose production of plasminogen activator inhibitor-1. Int J Obes Relat Metab Disord (2004) 1.43
Immunohistochemical and ultrastructural localization of leptin and leptin receptor in human white adipose tissue and differentiating human adipose cells in primary culture. Diabetes (2000) 1.43
[Therapeutic options for weight management in schizophrenic patients treated with atypical antipsychotics]. Fortschr Neurol Psychiatr (2008) 1.39
An epidemiological study of regional enteritis and acute ileitis in Copenhagen County. Scand J Gastroenterol (1973) 1.38
Purification and some properties of a monoacylglycerol-hydrolyzing enzyme of rat adipose tissue. J Biol Chem (1976) 1.37
Physiology: does gut hormone PYY3-36 decrease food intake in rodents? Nature (2004) 1.34
Insulin and cortisol promote leptin production in cultured human fat cells. Diabetes (1996) 1.33
Insulin-stimulated glucose transport in rat adipose cells. Modulation of transporter intrinsic activity by isoproterenol and adenosine. J Biol Chem (1986) 1.32
Activity and phosphorylation state of glucose transporters in plasma membranes from insulin-, isoproterenol-, and phorbol ester-treated rat adipose cells. J Biol Chem (1987) 1.29
Differential regulation of endogenous glucose-6-phosphatase and phosphoenolpyruvate carboxykinase gene expression by the forkhead transcription factor FKHR in H4IIE-hepatoma cells. Biochem Biophys Res Commun (2001) 1.28
Alterations of lipid metabolism in healthy volunteers during long-term ethanol intake. Eur J Clin Invest (1977) 1.26
GLUT8, a novel member of the sugar transport facilitator family with glucose transport activity. J Biol Chem (2000) 1.25
Direct costs of diabetes mellitus in Germany - CoDiM 2000-2007. Exp Clin Endocrinol Diabetes (2011) 1.25
Evidence that insulin and isoprenaline activate the cGMP-inhibited low-Km cAMP phosphodiesterase in rat fat cells by phosphorylation. Proc Natl Acad Sci U S A (1990) 1.23
Role of conserved arginine and glutamate residues on the cytosolic surface of glucose transporters for transporter function. Biochemistry (1997) 1.23
Adipose tissue fatty acid metabolism in insulin-resistant men. Diabetologia (2008) 1.23
Molecular cloning of a protein serine/threonine phosphatase containing a putative regulatory tetratricopeptide repeat domain. J Biol Chem (1994) 1.22
Cloning of two novel ADP-ribosylation factor-like proteins and characterization of their differential expression in 3T3-L1 cells. J Biol Chem (1994) 1.19
Prognostic significance of the therapeutic targets histone deacetylase 1, 2, 6 and acetylated histone H4 in cutaneous T-cell lymphoma. Histopathology (2008) 1.18
Essential mitotic functions of DNA topoisomerase IIalpha are not adopted by topoisomerase IIbeta in human H69 cells. J Biol Chem (1998) 1.16
ADP-ribosylation factor (ARF)-like 4, 6, and 7 represent a subgroup of the ARF family characterization by rapid nucleotide exchange and a nuclear localization signal. FEBS Lett (1999) 1.15
Relationship between replication and differentiation in cultured human adipocyte precursor cells. Am J Physiol (1996) 1.14
Demonstration of estrogen receptor subtypes alpha and beta in human adipose tissue: influences of adipose cell differentiation and fat depot localization. Mol Cell Endocrinol (2001) 1.14
Medical costs of diabetic complications total costs and excess costs by age and type of treatment results of the German CoDiM Study. Exp Clin Endocrinol Diabetes (2007) 1.13
Activation of direct and indirect pathways of glycogen synthesis by hepatic overexpression of protein targeting to glycogen. J Clin Invest (2000) 1.11
Cloning and characterization of DYRK1B, a novel member of the DYRK family of protein kinases. Biochem Biophys Res Commun (1999) 1.10
Electrolyte transport capacity and electrical potentials of the normal and the inflamed human rectum in vivo. Scand J Gastroenterol (1973) 1.08
Targeting of GLUT6 (formerly GLUT9) and GLUT8 in rat adipose cells. Biochem J (2001) 1.08
Transforming growth factor beta (TGF-beta) inhibits the differentiation of human adipocyte precursor cells in primary culture. Int J Obes Relat Metab Disord (1994) 1.08
Contribution of androgens to the gender difference in leptin production in obese children and adolescents. J Clin Invest (1997) 1.08
Distinctive regulatory and metabolic properties of glycogen-targeting subunits of protein phosphatase-1 (PTG, GL, GM/RGl) expressed in hepatocytes. J Biol Chem (2000) 1.08
Activity and genomic organization of human glucose transporter 9 (GLUT9), a novel member of the family of sugar-transport facilitators predominantly expressed in brain and leucocytes. Biochem J (2000) 1.07
Hormone-sensitive lipase of rat adipose tissue: identification and some properties of the enzyme protein. FEBS Lett (1977) 1.07
Tumor necrosis factor-alpha prevents the differentiation of human adipocyte precursor cells and causes delipidation of newly developed fat cells. J Clin Endocrinol Metab (1993) 1.06
A novel mechanism of cell killing by anti-topoisomerase II bisdioxopiperazines. J Biol Chem (2000) 1.06
Effects of suboptimal or excessive gestational weight gain on childhood overweight and abdominal adiposity: results from a retrospective cohort study. Int J Obes (Lond) (2013) 1.06
Adipocyte plasma membranes contain two Gi subtypes but are devoid of Go. FEBS Lett (1988) 1.06
Influence of Sibutramine on blood pressure: evidence from placebo-controlled trials. Int J Obes (Lond) (2005) 1.05
Genes and lifestyle factors in obesity: results from 12,462 subjects from MONICA/KORA. Int J Obes (Lond) (2010) 1.04
ARP is a plasma membrane-associated Ras-related GTPase with remote similarity to the family of ADP-ribosylation factors. J Biol Chem (1995) 1.04
Subcellular distribution and activity of glucose transporter isoforms GLUT1 and GLUT4 transiently expressed in COS-7 cells. Biochim Biophys Acta (1992) 1.03
Treatment of anthracycline extravasation with dexrazoxane. Clin Cancer Res (2000) 1.03
ADP-ribosylation factor (ARF)-like 3, a new member of the ARF family of GTP-binding proteins cloned from human and rat tissues. J Biol Chem (1994) 1.03
Type II diabetes mellitus and impaired glucose regulation in Caucasian children and adolescents with obesity living in Germany. Int J Obes Relat Metab Disord (2004) 1.02
Differentiation of erythrocyte-(GLUT1), liver-(GLUT2), and adipocyte-type (GLUT4) glucose transporters by binding of the inhibitory ligands cytochalasin B, forskolin, dipyridamole, and isobutylmethylxanthine. Mol Pharmacol (1991) 1.02
Sequential coexpression of the multidrug resistance genes MRP and mdr1 and their products in VP-16 (etoposide)-selected H69 small cell lung cancer cells. Cancer Res (1995) 1.02
A within-trial cost-effectiveness analysis of primary care referral to a commercial provider for weight loss treatment, relative to standard care--an international randomised controlled trial. Int J Obes (Lond) (2012) 1.01
Characterisation of a human small-cell lung cancer cell line resistant to the DNA topoisomerase I-directed drug topotecan. Br J Cancer (1995) 1.01
Differential sensitivity to guanine nucleotides of basal and insulin-stimulated glucose transporter activity reconstituted from adipocyte membrane fractions. FEBS Lett (1989) 1.01
Human breast adipocytes express interleukin-6 (IL-6) and its receptor system: increased IL-6 production by beta-adrenergic activation and effects of IL-6 on adipocyte function. J Clin Endocrinol Metab (2001) 1.00
The solvents cremophor EL and Tween 80 modulate daunorubicin resistance in the multidrug resistant Ehrlich ascites tumor. Cancer Commun (1990) 1.00
Tumor necrosis factor-alpha acutely inhibits insulin signaling in human adipocytes: implication of the p80 tumor necrosis factor receptor. Diabetes (1998) 1.00
Body fat distribution and steroid hormone concentrations in obese adolescent girls before and after weight reduction. J Clin Endocrinol Metab (1995) 0.99
Development of the hormone-sensitive glucose transport activity in differentiating 3T3-L1 murine fibroblasts. Role of the two transporter species and their subcellular localization. Biochem J (1990) 0.99
Diacylglycerol acyltransferase 1 inhibition with AZD7687 alters lipid handling and hormone secretion in the gut with intolerable side effects: a randomized clinical trial. Diabetes Obes Metab (2013) 0.99
Chinese hamster ovary cells resistant to the topoisomerase II catalytic inhibitor ICRF-159: a Tyr49Phe mutation confers high-level resistance to bisdioxopiperazines. Cancer Res (1998) 0.98
Chronic effects of a nonpeptide corticotropin-releasing hormone type I receptor antagonist on pituitary-adrenal function, body weight, and metabolic regulation. Endocrinology (1998) 0.98
A metabolic syndrome of hypertension, hyperinsulinaemia and hypercholesterolaemia in the New Zealand obese mouse. Eur J Clin Invest (2000) 0.97
Quality indicators for the prevention of type 2 diabetes in Europe--IMAGE. Horm Metab Res (2010) 0.97
Type 2 diabetes-like hyperglycemia in a backcross model of NZO and SJL mice: characterization of a susceptibility locus on chromosome 4 and its relation with obesity. Diabetes (2000) 0.96
Diet-induced gene expression of isolated pancreatic islets from a polygenic mouse model of the metabolic syndrome. Diabetologia (2009) 0.95
The signaling potential of the receptors for insulin and insulin-like growth factor I (IGF-I) in 3T3-L1 adipocytes: comparison of glucose transport activity, induction of oncogene c-fos, glucose transporter mRNA, and DNA-synthesis. J Cell Physiol (1991) 0.95
Hyperleptinemia, leptin resistance, and polymorphic leptin receptor in the New Zealand obese mouse. Endocrinology (1997) 0.95
Determination of protein in adipose tissue extracts. J Lipid Res (1976) 0.95
Modulation of insulin sensitivity by adenosine. Effects on glucose transport, lipid synthesis, and insulin receptors of the adipocyte. Mol Pharmacol (1982) 0.95
Forskolin inhibits insulin-stimulated glucose transport in rat adipose cells by a direct interaction with the glucose transporter. Mol Pharmacol (1987) 0.95
Alternative mRNA splicing of the novel GTPase Rab28 generates isoforms with different C-termini. Eur J Biochem (1996) 0.95
ATP-binding cassette transporter A1 (ABCA1) affects total body sterol metabolism. Gastroenterology (2001) 0.95
Expression, purification, and characterization of histidine-tagged mouse monoglyceride lipase from baculovirus-infected insect cells. Protein Expr Purif (2000) 0.95
Monoacylmonoalkylglycerol as a substrate for diacylglycerol hydrolase activity in adipose tissue. J Lipid Res (1978) 0.94
Obesity as an independent risk factor for decreased survival in node-positive high-risk breast cancer. Breast Cancer Res Treat (2015) 0.94
Evidence for the key role of the adipocyte cGMP-inhibited cAMP phosphodiesterase in the antilipolytic action of insulin. Biochim Biophys Acta (1995) 0.94
The vitamin D receptor gene variant is associated with the prevalence of type 2 diabetes mellitus and coronary artery disease. Diabet Med (2001) 0.94