Published in Eur J Cancer on November 01, 1996
Targeted therapy in non-small-cell lung cancer--is it becoming a reality? Nat Rev Clin Oncol (2010) 2.26
Gefitinib versus placebo in completely resected non-small-cell lung cancer: results of the NCIC CTG BR19 study. J Clin Oncol (2013) 1.75
Molecular biology of lung cancer: clinical implications. Clin Chest Med (2011) 1.47
Cross-talk between MET and EGFR in non-small cell lung cancer involves miR-27a and Sprouty2. Proc Natl Acad Sci U S A (2013) 1.24
Targeted therapy for non-small-cell lung cancer: past, present and future. Expert Rev Anticancer Ther (2013) 1.22
Targeted therapies for lung cancer: clinical experience and novel agents. Cancer J (2011) 1.17
Tankyrase and the canonical Wnt pathway protect lung cancer cells from EGFR inhibition. Cancer Res (2012) 1.16
EGFR targeted therapy in non-small cell lung cancer: potential role of cetuximab. Biologics (2009) 0.95
Modeling of tumor progression in NSCLC and intrinsic resistance to TKI in loss of PTEN expression. PLoS One (2012) 0.93
Randomised study of adjuvant chemotherapy for completely resected p-stage I-IIIA non-small cell lung cancer. Br J Cancer (2006) 0.89
High predictive value of epidermal growth factor receptor phosphorylation but not of EGFRvIII mutation in resected stage I non-small cell lung cancer (NSCLC). J Clin Pathol (2006) 0.89
Immunohistochemical typing of non-small cell lung cancer on cryostat sections: correlation with clinical parameters and prognosis. J Clin Pathol (2003) 0.86
The role of the epidermal growth factor receptor tyrosine kinase inhibitors as therapy for advanced, metastatic, and recurrent non-small-cell lung cancer: a Canadian national consensus statement. Curr Oncol (2009) 0.86
Epidermal growth factor receptor (EGFR) expression in operable non-small cell lung carcinoma. J Korean Med Sci (2004) 0.84
Trials to Overcome Drug Resistance to EGFR and ALK Targeted Therapies - Past, Present, and Future. Front Oncol (2014) 0.82
Optimizing the use of epidermal growth factor receptor inhibitors in advanced non-small-lung cancer (NSCLC). J Thorac Dis (2011) 0.80
Prognostic value of epidermal growth factor receptor expression in operable non-small cell lung carcinoma. Multidiscip Respir Med (2010) 0.78
Phase 1 study of romidepsin plus erlotinib in advanced non-small cell lung cancer. Lung Cancer (2015) 0.78
Standing the test of time in Europe? Gefitinib in the treatment of non-small-cell lung cancer. Lung Cancer (Auckl) (2010) 0.75
Erlotinib treatment in pretreated patients with non-small cell lung cancer: A Phase II study. Oncol Lett (2010) 0.75
A randomized, phase II study of gefitinib alone versus nimotuzumab plus gefitinib after platinum-based chemotherapy in advanced non-small cell lung cancer (KCSG LU12-01). Oncotarget (2016) 0.75
Role of the histone deacetylase complex in acute promyelocytic leukaemia. Nature (1998) 5.63
In vitro antibacterial properties of AT-2266, a new pyridonecarboxylic acid. Antimicrob Agents Chemother (1983) 5.45
Comparison of complete amino acid sequences and receptor-binding properties among 13 serotypes of hemagglutinins of influenza A viruses. Virology (1991) 4.85
Expression of cyclooxygenase-1 and -2 in human colorectal cancer. Cancer Res (1995) 4.52
Studies of the mortality of A-bomb survivors. 9. Mortality, 1950-1985: Part 2. Cancer mortality based on the recently revised doses (DS86). Radiat Res (1990) 4.18
Equilibrium centrifugation studies of hepatitis C virus: evidence for circulating immune complexes. J Virol (1993) 4.13
In vitro and in vivo activity of NY-198, a new difluorinated quinolone. Antimicrob Agents Chemother (1987) 3.84
New nalidixic acid resistance mutations related to deoxyribonucleic acid gyrase activity. J Bacteriol (1981) 3.65
Metalloproteinase-mediated release of human Fas ligand. J Exp Med (1995) 3.53
Epidemiologic studies of coronary heart disease and stroke in Japanese men living in Japan, Hawaii and California: prevalence of coronary and hypertensive heart disease and associated risk factors. Am J Epidemiol (1975) 3.26
Mode of incomplete cross-resistance among pipemidic, piromidic, and nalidixic acids. Antimicrob Agents Chemother (1978) 3.12
Two human homologues of Saccharomyces cerevisiae SWI2/SNF2 and Drosophila brahma are transcriptional coactivators cooperating with the estrogen receptor and the retinoic acid receptor. Nucleic Acids Res (1994) 2.81
Epidemiologic studies of coronary heart disease and stroke in Japanese men living in Japan, Hawaii and California: demographic, physical, dietary and biochemical characteristics. J Chronic Dis (1974) 2.78
Computed radiography utilizing scanning laser stimulated luminescence. Radiology (1983) 2.78
Hepatic resection for hepatocellular carcinoma. Clinical features and long-term prognosis. Ann Surg (1987) 2.69
Coronary aneurysms in infants and young children with acute febrile mucocutaneous lymph node syndrome. J Pediatr (1975) 2.66
Radioimmunoassay for tumor antigen of human cervical squamous cell carcinoma. Cancer (1977) 2.65
Role of autonomic nervous system in the pathogenesis of Prinzmetal's variant form of angina. Circulation (1974) 2.64
Molecular evidence from retroposons that whales form a clade within even-toed ungulates. Nature (1997) 2.63
Estimates of the prevalence of rheumatic diseases in the population of Tecumseh, Michigan, 1959-60. J Chronic Dis (1967) 2.63
Impact of sarcopenia on survival in patients undergoing living donor liver transplantation. Am J Transplant (2013) 2.51
Identification of toxigenic Clostridium difficile by the polymerase chain reaction. J Clin Microbiol (1991) 2.51
Twenty-year changes in the prevalence of overweight in Japanese adults: the National Nutrition Survey 1976-95. Obes Rev (2002) 2.35
Comparative study on adhesive performance of functional monomers. J Dent Res (2004) 2.32
Studies of the mortality of A-bomb survivors: 6. mortality and radiation dose, 1950--1974. Radiat Res (1978) 2.31
The SOCS box of SOCS-1 accelerates ubiquitin-dependent proteolysis of TEL-JAK2. J Biol Chem (2001) 2.29
Hematoporphyrin derivative and laser photoradiation in the treatment of lung cancer. Chest (1982) 2.29
EGFR regulation by microRNA in lung cancer: correlation with clinical response and survival to gefitinib and EGFR expression in cell lines. Ann Oncol (2008) 2.29
Upregulation of heme oxygenase-1 protects genetically fat Zucker rat livers from ischemia/reperfusion injury. J Clin Invest (1999) 2.29
Epidemiologic studies of coronary heart disease and stroke in Japanese men living in Japan, Hawaii and California. Incidence of myocardial infarction and death from coronary heart disease. Am J Cardiol (1977) 2.27
Altered cochlear fibrocytes in a mouse model of DFN3 nonsyndromic deafness. Science (1999) 2.25
Morphological correlates of increased coupling resistance at an electrotonic synapse. J Cell Biol (1971) 2.23
Fate of coronary aneurysms in Kawasaki disease: serial coronary angiography and long-term follow-up study. Am J Cardiol (1982) 2.22
Color Doppler evaluation of valvular regurgitation in normal subjects. Circulation (1988) 2.21
Biotin-containing intranuclear inclusions in endometrial glands during gestation and puerperium. Am J Clin Pathol (1993) 2.21
Correlation of fibrosis and transforming growth factor-beta type 2 levels in the eye. J Clin Invest (1989) 2.16
Rapid identification of 11 human intestinal Lactobacillus species by multiplex PCR assays using group- and species-specific primers derived from the 16S-23S rRNA intergenic spacer region and its flanking 23S rRNA. FEMS Microbiol Lett (2000) 2.13
The Palliative Prognostic Index: a scoring system for survival prediction of terminally ill cancer patients. Support Care Cancer (1999) 2.10
Kawasaki disease: effect of treatment on coronary artery involvement. Pediatrics (1979) 2.08
A prospective phase II study on photodynamic therapy with photofrin II for centrally located early-stage lung cancer. The Japan Lung Cancer Photodynamic Therapy Study Group. J Clin Oncol (1993) 2.02
Homocysteine-respondent genes in vascular endothelial cells identified by differential display analysis. GRP78/BiP and novel genes. J Biol Chem (1996) 2.01
Pendrin, the protein encoded by the Pendred syndrome gene (PDS), is an apical porter of iodide in the thyroid and is regulated by thyroglobulin in FRTL-5 cells. Endocrinology (2000) 2.01
Successful pregnancy after allogeneic bone marrow transplantation following conditioning with total body irradiation. Bone Marrow Transplant (1995) 2.01
Autosomal dominant moyamoya disease maps to chromosome 17q25.3. Neurology (2008) 2.00
Herp, a new ubiquitin-like membrane protein induced by endoplasmic reticulum stress. J Biol Chem (2000) 1.98
Characterization of a fission yeast SUMO-1 homologue, pmt3p, required for multiple nuclear events, including the control of telomere length and chromosome segregation. Mol Cell Biol (1999) 1.97
Rationale for bone marrow transplantation in the treatment of autoimmune diseases. Proc Natl Acad Sci U S A (1985) 1.97
Acute myeloid leukemia (AML) in Down's syndrome is highly responsive to chemotherapy: experience on Pediatric Oncology Group AML Study 8498. Blood (1992) 1.97
New fluorogenic substrates for alpha-thrombin, factor Xa, kallikreins, and urokinase. J Biochem (1977) 1.96
Polymorphism of the 5'-flanking region of the human tumor necrosis factor (TNF)-alpha gene in Japanese. Tissue Antigens (1998) 1.93
Liquid-gated interface superconductivity on an atomically flat film. Nat Mater (2009) 1.92
Chronic lymphocytic leukemic cells exhibit apoptotic signaling via TRAIL-R1. Cell Death Differ (2005) 1.90
Interaction of phytoestrogens with estrogen receptors alpha and beta. Biol Pharm Bull (2001) 1.90
RBP-L, a transcription factor related to RBP-Jkappa. Mol Cell Biol (1997) 1.89
Identification of ERSE-II, a new cis-acting element responsible for the ATF6-dependent mammalian unfolded protein response. J Biol Chem (2000) 1.89
Transforming growth factor-beta stimulates the expression of endothelin mRNA by vascular endothelial cells. Biochem Biophys Res Commun (1989) 1.88
Epidemiologic studies of coronary heart disease and stroke in Japanese men living in Japan, Hawaii and California: introduction. Am J Epidemiol (1975) 1.87
[Synthesis and bronchodilating activity of o-chloro-alpha-(tert-butylaminomethyl)-benzylalcohol hydrochloride (C-78) and related compounds (author's transl)]. Yakugaku Zasshi (1978) 1.87
The mechanism of activation of bovine factor IX (Christmas factor) by bovine factor XIa (activated plasma thromboplastin antecedent). Biochemistry (1974) 1.86
Molecular cloning and characterization of human estrogen receptor betacx: a potential inhibitor ofestrogen action in human. Nucleic Acids Res (1998) 1.85
Diagnosis of cardiac sarcoidosis and evaluation of the effects of steroid therapy by gadolinium-DTPA-enhanced magnetic resonance imaging. Am J Med (2001) 1.85
Assessment of noninvasive markers in identifying patients at risk in the Brugada syndrome: insight into risk stratification. J Am Coll Cardiol (2001) 1.84
A novel pathophysiologic phenomenon in cachexic patients with chronic obstructive pulmonary disease: the relationship between the circadian rhythm of circulating leptin and the very low-frequency component of heart rate variability. Am J Respir Crit Care Med (2001) 1.83
Four-year water degradation of total-etch adhesives bonded to dentin. J Dent Res (2003) 1.83
Immobilization stress causes oxidative damage to lipid, protein, and DNA in the brain of rats. FASEB J (1996) 1.83
Inhibitory effects of quinolone antibacterial agents on gamma-aminobutyric acid binding to receptor sites in rat brain membranes. Antimicrob Agents Chemother (1988) 1.83
Predictive value of vascular endothelial growth factor (VEGF) in metastasis and prognosis of human colorectal cancer. Br J Cancer (1998) 1.82
Impaired immunity in obesity: suppressed but reversible lymphocyte responsiveness. Int J Obes Relat Metab Disord (1993) 1.82
Reversal of long-term potentiation (depotentiation) induced by tetanus stimulation of the input to CA1 neurons of guinea pig hippocampal slices. Brain Res (1991) 1.81
The outer capsid protein of rice dwarf virus is encoded by genome segment S8. J Gen Virol (1989) 1.80
Functional evaluation of PTEN missense mutations using in vitro phosphoinositide phosphatase assay. Cancer Res (2000) 1.79
Long-term effect of tacrolimus therapy in patients with refractory ulcerative colitis. Aliment Pharmacol Ther (2008) 1.77
Coronary endothelial dysfunction after Kawasaki disease: evaluation by intracoronary injection of acetylcholine. J Am Coll Cardiol (1998) 1.77
The relationship between chronic hypoxemia and activation of the tumor necrosis factor-alpha system in patients with chronic obstructive pulmonary disease. Am J Respir Crit Care Med (2000) 1.77
The children of parents exposed to atomic bombs: estimates of the genetic doubling dose of radiation for humans. Am J Hum Genet (1990) 1.76
T-cell subsets in drug-induced toxic epidermal necrolysis. Possible pathogenic mechanism induced by CD8-positive T cells. Arch Dermatol (1991) 1.76
Experimental alteration of coupling resistance at an electrotonic synapse. J Cell Biol (1971) 1.74
Factor XI contributes to thrombus propagation on injured neointima of the rabbit iliac artery. J Thromb Haemost (2006) 1.74
Characterization of the human NDRG gene family: a newly identified member, NDRG4, is specifically expressed in brain and heart. Genomics (2001) 1.73
A parallel analysis of cancer mortality among atomic bomb survivors and patients with ankylosing spondylitis given X-ray therapy. J Natl Cancer Inst (1985) 1.72
Linkage map for Aedes aegypti using restriction fragment length polymorphisms. J Hered (1993) 1.71
The complete primary structure of human estrogen receptor beta (hER beta) and its heterodimerization with ER alpha in vivo and in vitro. Biochem Biophys Res Commun (1998) 1.71
Nosocomial outbreak of Clostridium difficile-associated diarrhoea due to a clindamycin-resistant enterotoxin A-negative strain. Eur J Clin Microbiol Infect Dis (2001) 1.71
Comparison of changes in jugular venous bulb oxygen saturation and cerebral oxygen saturation during variations of haemoglobin concentration under propofol and sevoflurane anaesthesia. Br J Anaesth (2004) 1.69
Studies of the mortality of A-bomb survivors. 5. Radiation dose and mortality, 1950-1970. Radiat Res (1972) 1.69
Antiproliferative activity of RAD001 (everolimus) as a single agent and combined with other agents in mantle cell lymphoma. Leukemia (2006) 1.67
A novel variant genotype C of hepatitis B virus identified in isolates from Australian Aborigines: complete genome sequence and phylogenetic relatedness. J Gen Virol (2001) 1.67
Association of increased platelet-associated immunoglobulins with thrombocytopenia and the severity of disease in secondary dengue virus infections. Clin Exp Immunol (2004) 1.66
Identification of and hydrogen peroxide production by fecal and vaginal lactobacilli isolated from Japanese women and newborn infants. J Clin Microbiol (1999) 1.66
Sophorolipids from Torulopsis bombicola: possible relation to alkane uptake. Appl Environ Microbiol (1982) 1.65
Riedel's lobe of the liver evaluated by multiple imaging modalities. Intern Med (2000) 1.64
Use of arbitrary primer PCR to type Clostridium difficile and comparison of results with those by immunoblot typing. J Clin Microbiol (1994) 1.63
Engineering of the major house dust mite allergen Der f 2 for allergen-specific immunotherapy. Nat Biotechnol (1997) 1.63
Highly sensitive peptide-4-methylcoumaryl-7-amide substrates for blood-clotting proteases and trypsin. Eur J Biochem (1988) 1.62
Conserved sequence motifs in the small subunit of human general transcription factor TFIIE. Nature (1991) 1.61
Studies of the mortality of A-bomb survivors. 9. Mortality, 1950-1985: Part 1. Comparison of risk coefficients for site-specific cancer mortality based on the DS86 and T65DR shielded kerma and organ doses. Radiat Res (1989) 1.61
Terminal sedation for existential distress. Am J Hosp Palliat Care (2002) 1.61
Primary systemic carnitine deficiency is caused by mutations in a gene encoding sodium ion-dependent carnitine transporter. Nat Genet (1999) 1.61
Phylogenetic analyses of Synechococcus strains (cyanobacteria) using sequences of 16S rDNA and part of the phycocyanin operon reveal multiple evolutionary lines and reflect phycobilin content. Int J Syst Evol Microbiol (2001) 1.61
Regulation of interleukin-1beta-induced interleukin-6 gene expression in human fibroblast-like synoviocytes by p38 mitogen-activated protein kinase. J Biol Chem (1998) 1.61