D T Downing

Author PubWeight™ 122.26‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Prolonged remissions of cystic and conglobate acne with 13-cis-retinoic acid. N Engl J Med 1979 4.87
2 Photodensitometry in the thin-layer chromatographic analysis of neutral lipids. J Chromatogr 1968 1.94
3 Enzyme inhibition by acetylenic compounds. Biochem Biophys Res Commun 1970 1.90
4 Control of free fatty acids in human surface lipids by Corynebacterium acnes. J Invest Dermatol 1971 1.82
5 Sustainable rates of sebum secretion in acne patients and matched normal control subjects. J Am Acad Dermatol 1983 1.72
6 Amyloid fibrils may be assembled from beta-helical protofibrils. Biochemistry 1998 1.67
7 Age-related changes in sebaceous gland activity. J Invest Dermatol 1979 1.63
8 Inhibition of prostaglandin biosynthesis by eicosa-5,8,11,14-tetraynoic acid. Biochim Biophys Acta 1970 1.59
9 Presence of intact intercellular lipid lamellae in the upper layers of the stratum corneum. J Invest Dermatol 1987 1.57
10 Ceramides of pig epidermis: structure determination. J Lipid Res 1983 1.45
11 The origin of alkanes found in human skin surface lipids. J Invest Dermatol 1989 1.44
12 Anatomical variation in the amount and composition of human skin surface lipid. J Invest Dermatol 1970 1.41
13 The effect of marked inhibition of sebum production with 13cis-retinoic acid on skin surface lipid composition. J Invest Dermatol 1980 1.35
14 Composition and morphology of epidermal cyst lipids. J Invest Dermatol 1987 1.32
15 Chemistry and function of mammalian sebaceous lipids. Adv Lipid Res 1991 1.27
16 Molecular models of the intercellular lipid lamellae in mammalian stratum corneum. J Invest Dermatol 1989 1.26
17 Evidence that the corneocyte has a chemically bound lipid envelope. J Invest Dermatol 1987 1.25
18 The composition of the ceramides from human stratum corneum and from comedones. J Invest Dermatol 1985 1.21
19 Differential inhibition of prostaglandin synthetase and soybean lipoxygenase. Prostaglandins 1972 1.19
20 Effect of essential fatty acid deficiency on the epidermal sphingolipids of the rat. Biochim Biophys Acta 1983 1.18
21 Chemical composition of human skin surface lipids from birth to puberty. J Invest Dermatol 1970 1.14
22 Covalently bound omega-hydroxyacylsphingosine in the stratum corneum. Biochim Biophys Acta 1987 1.11
23 Covalently bound lipids of human stratum corneum. J Invest Dermatol 1989 1.10
24 6-Hydroxy-4-sphingenine in human epidermal ceramides. J Lipid Res 1994 1.08
25 Variability in the chemical composition of human skin surface lipids. J Invest Dermatol 1969 1.06
26 Lipid organization in pig stratum corneum. J Lipid Res 1995 1.03
27 Essential fatty acids and acne. J Am Acad Dermatol 1986 1.03
28 Glycolipids in mammalian epidermis: structure and function in the water barrier. Science 1982 1.02
29 Human stratum corneum polar lipids and desquamation. Arch Dermatol Res 1985 1.01
30 A new 6-hydroxy-4-sphingenine-containing ceramide in human skin. J Lipid Res 1999 1.00
31 Essential fatty acids and epidermal integrity. Arch Dermatol 1987 1.00
32 Preparation of liposomes from stratum corneum lipids. J Invest Dermatol 1986 0.99
33 Influence of Pityrosporum species in the generation of free fatty acids in human surface lipids. J Invest Dermatol 1972 0.98
34 Quantitative assessment of the persistent antimitotic effect of certain hepatotoxic pyrrolizidine alkaloids on rat liver. Aust J Exp Biol Med Sci 1968 0.98
35 Octadecadienoic acids in the skin surface lipids of acne patients and normal subjects. J Invest Dermatol 1976 0.98
36 X-ray diffraction analysis of isolated skin lipids: reconstitution of intercellular lipid domains. Biochemistry 1996 0.98
37 Age-related changes in sebaceous wax ester secretion rates in men and women. J Invest Dermatol 1985 0.97
38 Murine keratinocyte cultures grown at the air/medium interface synthesize stratum corneum lipids and "recycle" linoleate during differentiation. J Invest Dermatol 1989 0.94
39 Fatty acids of acylceramides from comedones and from the skin surface of acne patients and control subjects. J Invest Dermatol 1988 0.93
40 Sphingolipids of the stratum corneum and lamellar granules of fetal rat epidermis. J Invest Dermatol 1984 0.93
41 Stratum corneum lipid liposomes: calcium-induced transformation into lamellar sheets. J Invest Dermatol 1987 0.92
42 Measurement of sebum secretion rates in young children. J Invest Dermatol 1985 0.92
43 Effect of oral 13-cis-retinoic acid at three dose levels on sustainable rates of sebum secretion and on acne. J Am Acad Dermatol 1983 0.92
44 Dilutional effect of increased sebaceous gland activity on the proportion of linoleic acid in sebaceous wax esters and in epidermal acylceramides. J Invest Dermatol 1986 0.91
45 The sebaceous glands: twenty-five years of progress. J Invest Dermatol 1976 0.91
46 Lipids of chicken epidermis. J Lipid Res 1986 0.91
47 Ceramidase activity in porcine epidermis. FEBS Lett 1990 0.91
48 Sphingolipid metabolism in organotypic mouse keratinocyte cultures. J Invest Dermatol 1990 0.90
49 Free sphingosines in porcine epidermis. Biochim Biophys Acta 1989 0.90
50 Acylglucosylceramides of pig epidermis: structure determination. J Lipid Res 1983 0.90
51 Free sphingosine in human epidermis. J Invest Dermatol 1990 0.89
52 Lipid composition of cohesive and desquamated corneocytes from mouse ear skin. J Invest Dermatol 1986 0.89
53 Lamellar granule extrusion and stratum corneum intercellular lamellae in murine keratinocyte cultures. J Invest Dermatol 1988 0.89
54 The time course of lipid formation in human sebaceous glands. J Invest Dermatol 1977 0.89
55 Fusion patterns of liposomes formed from stratum corneum lipids. J Invest Dermatol 1988 0.89
56 Skin surface lipids of the dog. Lipids 1977 0.89
57 Effects of essential fatty acid deficiency on epidermal O-acylsphingolipids and transepidermal water loss in young pigs. Biochim Biophys Acta 1987 0.89
58 The role of the corneocyte lipid envelopes in cohesion of the stratum corneum. J Invest Dermatol 1989 0.88
59 Fibril formation by amyloid-beta proteins may involve beta-helical protofibrils. J Pept Res 1999 0.87
60 Integral lipids of mammalian hair. Comp Biochem Physiol B 1989 0.87
61 Composition of cerumen lipids. J Am Acad Dermatol 1990 0.86
62 Metabolism of linoleic acid in porcine epidermis. J Lipid Res 1990 0.86
63 The effect of accumulated lipids on measurements of sebum secretion in human skin. J Invest Dermatol 1982 0.86
64 Skin lipids: an update. J Invest Dermatol 1987 0.86
65 Sebaceous gland response in man to prolonged total caloric deprivation. J Invest Dermatol 1970 0.86
66 Integral lipids of human hair. Lipids 1988 0.85
67 Variability in the fatty acid composition of wax esters from vernix caseosa and its possible relation to sebaceous gland activity. J Invest Dermatol 1982 0.85
68 Identification of a fatty acid in human skin surface lipids apparently associated with acne vulgaris. J Invest Dermatol 1973 0.85
69 Circular dichroism of model peptides emulating the amphipathic alpha-helical regions of intermediate filaments. Biochemistry 1997 0.85
70 On the mechanism of sebaceous secretion. Arch Dermatol Res 1982 0.84
71 Changes in skin surface lipid composition induced by severe caloric restriction in man. Am J Clin Nutr 1972 0.84
72 The time course of lipid biosynthesis in pig epidermis. J Invest Dermatol 1988 0.84
73 Skin surface lipid composition, acne, pubertal development, and urinary excretion of testosterone and 17-ketosteroids in children. J Invest Dermatol 1977 0.84
74 Linoleate-rich acylglucosylceramides of pig epidermis: structure determination by proton magnetic resonance. J Lipid Res 1985 0.83
75 Variation in sebum fatty acid composition among adult humans. J Invest Dermatol 1984 0.83
76 Lipids of epidermis and keratinized and non-keratinized oral epithelia. Comp Biochem Physiol B 1986 0.83
77 Free sphingosines of human skin include 6-hydroxysphingosine and unusually long-chain dihydrosphingosines. J Invest Dermatol 1995 0.83
78 Covalent attachment of omega-hydroxyacid derivatives to epidermal macromolecules: a preliminary characterization. Biochem Biophys Res Commun 1986 0.83
79 Separation of wax esters from steryl esters by chromatography on magnesium hydroxide. Lipids 1981 0.83
80 A mixture of alpha-helical and 3(10)-helical conformations for involucrin in the human epidermal corneocyte envelope provides a scaffold for the attachment of both lipids and proteins. J Biol Chem 1999 0.82
81 The nonpolar lipids of pig epidermis. J Invest Dermatol 1988 0.82
82 Preparation of model membranes for skin permeability studies using stratum corneum lipids. J Invest Dermatol 1989 0.82
83 A survey of polar and nonpolar lipids extracted from snake skin. Comp Biochem Physiol B 1985 0.81
84 Acne: perspectives. J Invest Dermatol 1974 0.81
85 Skin lipids. Comp Biochem Physiol B 1983 0.81
86 Deuterium NMR investigation of polymorphism in stratum corneum lipids. Biochim Biophys Acta 1991 0.81
87 Effect of epidermal acylglucosylceramides and acylceramides on the morphology of liposomes prepared from stratum corneum lipids. Biochim Biophys Acta 1988 0.81
88 Beta-helical fibrils from a model peptide. Biochem Biophys Res Commun 1997 0.81
89 Isolation of corneocyte envelopes from porcine epidermis. Arch Dermatol Res 1988 0.81
90 Measurement of the time between synthesis and surface excretion of sebaceous lipids in sheep and man. J Invest Dermatol 1975 0.81
91 The role of lipids in the epidermal barrier to water diffusion. J Invest Dermatol 1970 0.80
92 The lipid composition of porcine epidermis and oral epithelium. Arch Oral Biol 1986 0.80
93 Glucosylsterol and acylglucosylsterol of snake epidermis: structure determination. J Lipid Res 1987 0.80
94 Changes in the relative amounts of endogenous and exogenous fatty acids in sebaceous lipids during early adolescence. J Invest Dermatol 1989 0.80
95 Lipid composition of cultured murine keratinocytes. J Invest Dermatol 1986 0.80
96 The fatty acids of human sebaceous gland phosphatidylcholine. Biochim Biophys Acta 1978 0.80
97 Proportions of various straight and branched fatty acid chain types in the sebaceous wax esters of young children. J Invest Dermatol 1985 0.80
98 Lipids are covalently attached to rigid corneocyte protein envelopes existing predominantly as beta-sheets: a solid-state nuclear magnetic resonance study. J Invest Dermatol 1995 0.80
99 Estimation of sebum production rates in man by measurement of the squalene content of skin biopsies. J Invest Dermatol 1981 0.79
100 The omega-hydroxyceramides of pig epidermis are attached to corneocytes solely through omega-hydroxyl groups. J Lipid Res 2001 0.79
101 The effect of 13-cis-retinoic acid on sebaceous glands. Arch Dermatol 1987 0.79
102 Metabolism of topically applied fatty acid methyl esters in BALB/C mouse epidermis. J Dermatol Sci 1990 0.79
103 Skin surface lipids of the mole Scalopus aquaticus. Comp Biochem Physiol B 1987 0.79
104 The role of the aerobic microflora in the genesis of fatty acids in human surface lipids. J Invest Dermatol 1970 0.78
105 Analysis of soluble proteins in comedones. Acta Derm Venereol 1977 0.78
106 Freeze-fracture electron microscopic and osmotic water permeability studies of epidermal lipid liposomes derived from stratum corneum lipids of porcine epidermis. Acta Derm Venereol 1993 0.78
107 Interaction between corneocytes and stratum corneum lipid liposomes in vitro. Biochim Biophys Acta 1990 0.78
108 Cholesterol sulfate protects Candida albicans from inhibition by sphingosine in vitro. J Invest Dermatol 1996 0.78
109 Lamellar structures formed by stratum corneum lipids in vitro: a deuterium nuclear magnetic resonance (NMR) study. Pharm Res 1992 0.78
110 Suppression of sebum secretion with 13-cis-retinoic acid: effect on individual skin surface lipids and implications for their anatomic origin. J Invest Dermatol 1984 0.78
111 Stabilization of amphipathic alpha-helical and beta-helical conformations in synthetic peptides in the presence and absence of ionic interactions. J Pept Res 1998 0.77
112 Hydroxyacid derivatives in human epidermis. Lipids 1988 0.77
113 Beta-glucosidase activity in porcine epidermis. Biochim Biophys Acta 1989 0.77
114 Sebaceous gland activity and serum dehydroepiandrosterone sulfate levels in boys and girls. Arch Dermatol 1992 0.77
115 Occurrence of squalene in skin surface lipids of the otter, the beaver and the kinkajou. Lipids 1980 0.76
116 A survey of polar and non-polar lipids of mouse organs. Comp Biochem Physiol B 1985 0.76
117 Skin surface lipids of the horse. Lipids 1980 0.76
118 A survey of polar and nonpolar lipids from epidermis and epidermal appendages of the chicken (Gallus domesticus). Comp Biochem Physiol B 1986 0.76
119 Sclerosing lipogranuloma of the male genitalia containing vitamin E: a comparison with classical "paraffinoma". J Am Acad Dermatol 1983 0.76
120 The time-course of lipid biosynthesis in horse skin. Biochim Biophys Acta 1985 0.76
121 Changes in sebum secretion and the sebaceous gland. Dermatol Clin 1986 0.76
122 omega-Hydroxyacid derivatives in the epidermis of several mammalian species. Comp Biochem Physiol B 1989 0.75
123 Evaluation of a method for measuring the sustainable rate of sebaceous wax ester secretion. Arch Dermatol Res 1987 0.75
124 Effect of cyproterone acetate-ethinyl estradiol treatment on the proportions of linoleic and sebaleic acids in various skin surface lipid classes. Arch Dermatol Res 1986 0.75
125 Linoleate content of epidermal acylglucosylceramide in newborn, growing and mature mice. Biochim Biophys Acta 1986 0.75
126 Polar lipid composition of mammalian hair. Comp Biochem Physiol B 1987 0.75
127 Skin lipids of the Florida indigo snake. Lipids 1974 0.75
128 Structural requirements of acetylenic fatty acids for inhibition of soybean lipoxygenase and prostaglandin synthetase. Biochim Biophys Acta 1972 0.75
129 Glucosylceramides of pig epidermis: structure determination. J Lipid Res 1983 0.75
130 Membrane structural alterations in murine stratum corneum: relationship to the localization of polar lipids and phospholipases. J Invest Dermatol 1989 0.75
131 Structures of the dienoic lactones of horse sebum. Comp Biochem Physiol B 1984 0.75
132 Comparison of acetate and glucose incorporation into rat and horse skin lipids. Biochim Biophys Acta 1985 0.75
133 Skin surface lipids of the mink. Comp Biochem Physiol B 1986 0.75
134 Trans-unsaturated fatty acids in human skin surface lipids. J Invest Dermatol 1976 0.75
135 Comparison of the hydroxyacids from the epidermis and from the sebaceous glands of the horse. Comp Biochem Physiol B 1983 0.75
136 Skin surface lipids of the guinea pig. Biochim Biophys Acta 1976 0.75
137 Skin surface lipids of the cow. Comp Biochem Physiol B 1982 0.75
138 Effects of Na2SO4 on hydrophobic and electrostatic interactions between amphipathic alpha-helices. J Pept Res 2001 0.75
139 Methylation of fatty acids by pyrolysis of their tetramethylammonium salts in the gas chromatograph. Anal Chem 1968 0.75
140 Double bond positions in the unsaturated fatty acids of vernix caseosa. J Invest Dermatol 1968 0.75
141 Skin lipids and acne. Annu Rev Med 1975 0.75
142 Uropygiols: confirmation of structure by proton magnetic resonance. J Lipid Res 1985 0.75
143 Nutritional influences of pellagra on sebum composition. Br J Dermatol 1977 0.75
144 Cholesteryl sulfate: the major polar lipid of horse hoof. J Lipid Res 1984 0.75
145 Unusual cholesterol esters in the sebum of young children. J Invest Dermatol 1990 0.75
146 Possible genetic control of the proportions of branched-chain fatty acids in human sebaceous wax esters. J Invest Dermatol 1986 0.75
147 The effect of lipids on transepidermal water permeation in snakes. Comp Biochem Physiol A Comp Physiol 1985 0.75
148 Variables associated with skin dryness in the elderly. Nurs Res 1986 0.75
149 Surface lipid composition in children with protein-calorie malnutrition. Am J Clin Nutr 1978 0.75
150 Acylglucosylceramide causes flattening and stacking of liposomes. An analogy for assembly of the epidermal permeability barrier. Biochim Biophys Acta 1984 0.75
151 Variation in skin surface lipid composition among the Equidae. Comp Biochem Physiol B 1983 0.75
152 The role of skin lipids in acne. Cutis 1976 0.75
153 The time course of sebum secretion in the guinea-pig. Comp Biochem Physiol B 1985 0.75
154 Measurement of the time between biosynthesis and surface excretion of sebaceous lipids in the horse. Biochim Biophys Acta 1985 0.75
155 Lipolysis by human skin surface debris in organic solvents. J Invest Dermatol 1970 0.75
156 The polar lipids from keratinized tissues of some vertebrates. Comp Biochem Physiol B 1982 0.75