A C Hayday

Author PubWeight™ 110.58‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Enhanced growth of mice lacking the cyclin-dependent kinase inhibitor function of p27(Kip1). Cell 1996 7.69
2 Regulation of cutaneous malignancy by gammadelta T cells. Science 2001 5.83
3 Complete primary structure of a heterodimeric T-cell receptor deduced from cDNA sequences. Nature 1984 5.19
4 Structure, organization, and somatic rearrangement of T cell gamma genes. Cell 1985 3.49
5 A third rearranged and expressed gene in a clone of cytotoxic T lymphocytes. Nature 1984 3.46
6 Activation of the c-myc gene by translocation: a model for translational control. Proc Natl Acad Sci U S A 1983 3.36
7 Activation of a translocated human c-myc gene by an enhancer in the immunoglobulin heavy-chain locus. Nature 1984 2.93
8 Lymphoid development in mice congenitally lacking T cell receptor alpha beta-expressing cells. Science 1992 2.90
9 T cell receptor-alpha beta-deficient mice fail to develop colitis in the absence of a microbial environment. Am J Pathol 1997 2.76
10 Electric field-mediated DNA transfer: transient and stable gene expression in human and mouse lymphoid cells. Mol Cell Biol 1986 2.51
11 Productive T-cell receptor beta-chain gene rearrangement: coincident regulation of cell cycle and clonality during development in vivo. Genes Dev 1996 2.47
12 Constitutive activation of NF-kappaB and T-cell leukemia/lymphoma in Notch3 transgenic mice. EMBO J 2000 2.41
13 Unusual organization and diversity of T-cell receptor alpha-chain genes. Nature 1985 2.36
14 Biological insights into TCRgammadelta+ and TCRalphabeta+ intraepithelial lymphocytes provided by serial analysis of gene expression (SAGE). Immunity 2001 2.29
15 T cell receptor beta chain gene rearrangement and selection during thymocyte development in adult mice. Immunity 1994 2.20
16 A novel disulfide-linked heterodimer on pre-T cells consists of the T cell receptor beta chain and a 33 kd glycoprotein. Cell 1993 2.04
17 Immunoglobulin synthesis and generalized autoimmunity in mice congenitally deficient in alpha beta(+) T cells. Nature 1994 1.94
18 T-cell alpha beta + and gamma delta + deficient mice display abnormal but distinct phenotypes toward a natural, widespread infection of the intestinal epithelium. Proc Natl Acad Sci U S A 1996 1.92
19 NF-kappa B activation by the pre-T cell receptor serves as a selective survival signal in T lymphocyte development. Immunity 2000 1.91
20 Defining the specific physiological requirements for c-Myc in T cell development. Nat Immunol 2001 1.65
21 Activation of a translocated c-myc gene: role of structural alterations in the upstream region. Proc Natl Acad Sci U S A 1984 1.61
22 Rearrangement and diversity of T cell receptor beta chain genes in thymocytes: a critical role for the beta chain in development. Cell 1993 1.59
23 In vivo manipulation of Vgamma9Vdelta2 T cells with zoledronate and low-dose interleukin-2 for immunotherapy of advanced breast cancer patients. Clin Exp Immunol 2010 1.58
24 Propagation and regulation of systemic autoimmunity by gammadelta T cells. J Immunol 1996 1.52
25 Conservation of T cell receptor conformation in epidermal gammadelta cells with disrupted primary Vgamma gene usage. Science 1998 1.51
26 Suppression of airway inflammation by a natural acute infection of the intestinal epithelium. Mucosal Immunol 2008 1.44
27 Germinal center formation, immunoglobulin class switching, and autoantibody production driven by "non alpha/beta" T cells. J Exp Med 1996 1.42
28 Murine lupus in the absence of alpha beta T cells. J Immunol 1996 1.41
29 The imprint of intrathymic self-peptides on the mature T cell receptor repertoire. Immunity 1997 1.35
30 Cytokines in T-cell development. Immunol Today 1991 1.26
31 Raf regulates positive selection. Eur J Immunol 1996 1.21
32 A tumor-suppressor function for Fas (CD95) revealed in T cell-deficient mice. J Exp Med 1996 1.20
33 Lymphocyte proliferation in mice congenitally deficient in T-cell receptor alpha beta + cells. Proc Natl Acad Sci U S A 1994 1.20
34 Developmentally regulated fetal thymic and extrathymic T-cell receptor gamma delta gene expression. Genes Dev 1990 1.16
35 Alpha beta and gamma delta T cells can share a late common precursor. Curr Biol 1995 1.15
36 Dynamic response of murine gut intraepithelial T cells after infection by the coccidian parasite Eimeria. Eur J Immunol 1993 1.13
37 Intrathymic delta selection events in gammadelta cell development. Immunity 1997 1.08
38 Germinal center formation in mice lacking alpha beta T cells. Eur J Immunol 1996 1.08
39 Developmental control of lymphokine gene expression in fetal thymocytes during T-cell ontogeny. Proc Natl Acad Sci U S A 1989 1.07
40 Regulated expression and structure of T cell receptor gamma/delta transcripts in human thymic ontogeny. EMBO J 1991 1.07
41 Gamma delta T cell help of B cells is induced by repeated parasitic infection, in the absence of other T cells. Curr Biol 1996 1.05
42 The expression in vivo of a second isoform of pT alpha: implications for the mechanism of pT alpha action. J Immunol 1998 1.05
43 TCR gene recombination and alpha beta-gamma delta lineage divergence: productive TCR-beta rearrangement is neither exclusive nor preclusive of gamma delta cell development. J Immunol 1996 1.01
44 Widespread expression of an autoantigen-GAD65 transgene does not tolerize non-obese diabetic mice and can exacerbate disease. Proc Natl Acad Sci U S A 1998 1.00
45 Loss of polyoma virus infectivity as a result of a single amino acid change in a region of polyoma virus large T-antigen which has extensive amino acid homology with simian virus 40 large T-antigen. J Virol 1983 0.98
46 Disruption of epithelial gamma delta T cell repertoires by mutation of the Syk tyrosine kinase. Proc Natl Acad Sci U S A 1996 0.98
47 Establishing humanized mice using stem cells: maximizing the potential. Clin Exp Immunol 2008 0.97
48 Pathogenesis of autoimmunity in alphabeta T cell-deficient lupus-prone mice. Clin Exp Immunol 1998 0.97
49 alpha beta T cell regulation and CD40 ligand dependence in murine systemic autoimmunity. J Immunol 1997 0.96
50 Genetic dissection of primary and secondary responses to a widespread natural pathogen of the gut, Eimeria vermiformis. Infect Immun 2000 0.95
51 Gamma delta T cells from tolerized alpha beta T cell receptor (TCR)-deficient mice inhibit contact sensitivity-effector T cells in vivo, and their interferon-gamma production in vitro. J Exp Med 1996 0.94
52 The cloning and characterization of a murine secretory leukocyte protease inhibitor cDNA. Biochem Biophys Res Commun 1997 0.92
53 Expression of the alpha beta T-cell receptor is necessary for the generation of the thymic medulla. Dev Immunol 1993 0.92
54 The biological activity of natural and mutant pTalpha alleles. J Exp Med 2001 0.90
55 An alphabeta T-cell-independent immunoprotective response towards gut coccidia is supported by gammadelta cells. Immunology 2000 0.89
56 Transcripts of functionally rearranged gamma genes in primary T cells of adult immunocompetent mice. Nature 1986 0.88
57 T cell development and repertoire of mice expressing a single T cell receptor alpha chain. Eur J Immunol 1995 0.86
58 Gamma(delta) T cells: non-classical ligands for non-classical cells. Curr Biol 2000 0.84
59 Genetic analysis of the essential components of the immunoprotective response to infection with Eimeria vermiformis. Int J Parasitol 1998 0.84
60 Immune responsiveness in mutant mice lacking T-cell receptor alpha beta+ cells. Immunology 1995 0.82
61 Gamma delta T-cell help in responses to pathogens and in the development of systemic autoimmunity. Immunol Res 1997 0.81
62 Transcriptional modulation of the human intercellular adhesion molecule gene I (ICAM-1) by retinoic acid in melanoma cells. Exp Cell Res 1995 0.80
63 Gamma delta T-cell lines isolated from intestinal epithelium respond to a B-cell lymphoma. Immunology 1993 0.78
64 Gamma/delta T cells from tolerized alpha/beta-TCR-deficient mice antigen specifically inhibit contact sensitivity in vivo and IFN-gamma production in vitro. Int Arch Allergy Immunol 1997 0.78
65 Expansion of gamma delta+ T cells in BALB/c mice infected with Leishmania major is dependent upon Th2-type CD4+ T cells. Infect Immun 1995 0.77
66 Thymic and extrathymic development of human gamma/delta T cells. Curr Top Microbiol Immunol 1991 0.76
67 Heavy-metal modulation of the human intercellular adhesion molecule (ICAM-1) gene expression. Biochim Biophys Acta 1995 0.76
68 gamma delta cells in gut infection, immunopathology, and organogenesis. Springer Semin Immunopathol 2000 0.75
69 T-cell receptor gene rearrangement in primary tumors: effect of genetic background and inducing agent. Immunogenetics 1988 0.75