Antineoplastic agents. 362. Isolation and X-ray crystal structure of dibromophakellstatin from the Indian ocean sponge Phakellia mauritiana.

PubWeight™: 0.92‹?›

🔗 View Article (PMID 9051914)

Published in J Nat Prod on February 01, 1997

Authors

G R Pettit1, J McNulty, D L Herald, D L Doubek, J C Chapuis, J M Schmidt, L P Tackett, M R Boyd

Author Affiliations

1: Department of Chemistry, Arizona State University, Tempe 85287-2404, USA.

Articles by these authors

New colorimetric cytotoxicity assay for anticancer-drug screening. J Natl Cancer Inst (1990) 23.46

Feasibility of drug screening with panels of human tumor cell lines using a microculture tetrazolium assay. Cancer Res (1988) 9.96

Evaluation of a soluble tetrazolium/formazan assay for cell growth and drug sensitivity in culture using human and other tumor cell lines. Cancer Res (1988) 8.53

Display and analysis of patterns of differential activity of drugs against human tumor cell lines: development of mean graph and COMPARE algorithm. J Natl Cancer Inst (1989) 4.97

The development of cellular stalks in bacteria. J Cell Biol (1966) 4.22

Comparison of in vitro anticancer-drug-screening data generated with a tetrazolium assay versus a protein assay against a diverse panel of human tumor cell lines. J Natl Cancer Inst (1990) 4.08

New soluble-formazan assay for HIV-1 cytopathic effects: application to high-flux screening of synthetic and natural products for AIDS-antiviral activity. J Natl Cancer Inst (1989) 4.04

Observations on the adsorption of Caulobacter bacteriophages containing ribonucleic acid. J Gen Microbiol (1966) 3.19

Prostratin: activation of latent HIV-1 expression suggests a potential inductive adjuvant therapy for HAART. Blood (2001) 2.88

Morphological and immunocytochemical characteristics of human tumor cell lines for use in a disease-oriented anticancer drug screen. Anticancer Res (1992) 2.62

Solution structure of cyanovirin-N, a potent HIV-inactivating protein. Nat Struct Biol (1998) 2.19

Antiherpesvirus activity of 9-(4-hydroxy-3-hydroxy-methylbut-1-yl)guanine (BRL 39123) in cell culture. Antimicrob Agents Chemother (1987) 2.11

Tetrazolium-based assays for cellular viability: a critical examination of selected parameters affecting formazan production. Cancer Res (1991) 2.06

Antineoplastic agents. 291. Isolation and synthesis of combretastatins A-4, A-5, and A-6(1a) J Med Chem (1995) 1.98

Development of human tumor cell line panels for use in disease-oriented drug screening. Prog Clin Biol Res (1988) 1.95

The calanolides, a novel HIV-inhibitory class of coumarin derivatives from the tropical rainforest tree, Calophyllum lanigerum. J Med Chem (1992) 1.89

Cerebrovascular reactivity and vasospasm after subarachnoid hemorrhage: a pilot study. Neurology (2006) 1.78

Isolation, structure, and synthesis of combretastatins A-1 and B-1, potent new inhibitors of microtubule assembly, derived from Combretum caffrum. J Nat Prod (1987) 1.64

Fever after subarachnoid hemorrhage: risk factors and impact on outcome. Neurology (2007) 1.61

Crystal structure of cyanovirin-N, a potent HIV-inactivating protein, shows unexpected domain swapping. J Mol Biol (1999) 1.57

Cyanovirin-N binds to gp120 to interfere with CD4-dependent human immunodeficiency virus type 1 virion binding, fusion, and infectivity but does not affect the CD4 binding site on gp120 or soluble CD4-induced conformational changes in gp120. J Virol (1999) 1.57

Interactions of tubulin with potent natural and synthetic analogs of the antimitotic agent combretastatin: a structure-activity study. Mol Pharmacol (1988) 1.54

Cytotoxic geranyl stilbenes from Macaranga schweinfurthii. J Nat Prod (1998) 1.50

Selection of an oral prodrug (BRL 42810; famciclovir) for the antiherpesvirus agent BRL 39123 [9-(4-hydroxy-3-hydroxymethylbut-l-yl)guanine; penciclovir]. Antimicrob Agents Chemother (1989) 1.48

Antineoplastic agents 322. synthesis of combretastatin A-4 prodrugs. Anticancer Drug Des (1995) 1.46

Self-consistent Karplus parametrization of 3J couplings depending on the polypeptide side-chain torsion chi1. J Am Chem Soc (2001) 1.42

Evidence for the Clara cell as a site of cytochrome P450-dependent mixed-function oxidase activity in lung. Nature (1977) 1.41

Analysis of nonnucleoside drug-resistant variants of human immunodeficiency virus type 1 reverse transcriptase. J Virol (1993) 1.41

Isolation and structures of schleicherastatins 1-7 and schleicheols 1 and 2 from the teak forest medicinal tree Schleichera oleosa. J Nat Prod (2000) 1.40

Pancratistatin: a natural anti-cancer compound that targets mitochondria specifically in cancer cells to induce apoptosis. Apoptosis (2005) 1.35

Isolation and structure of the cell growth inhibitory constituents from the western Pacific marine sponge Axinella sp. J Med Chem (1991) 1.32

Cyanovirin-N defines a new class of antiviral agent targeting N-linked, high-mannose glycans in an oligosaccharide-specific manner. Mol Pharmacol (2001) 1.31

Extrapulmonary, tissue-specific metastasis formation in nude mice injected with FEMX-I human melanoma cells. Cancer Res (1988) 1.29

Selective interactions of the human immunodeficiency virus-inactivating protein cyanovirin-N with high-mannose oligosaccharides on gp120 and other glycoproteins. J Pharmacol Exp Ther (2001) 1.28

Ultrastructural study of crossbands occurring in the stalks of Caulobacter crescentus. J Bacteriol (1973) 1.27

Effect of interferon alfa on the dynamics of hepatitis C virus turnover in vivo. Hepatology (1996) 1.27

Antineoplastic agents, 256. Cell growth inhibitory isocarbostyrils from Hymenocallis. J Nat Prod (1993) 1.26

Multiple antiviral activities of cyanovirin-N: blocking of human immunodeficiency virus type 1 gp120 interaction with CD4 and coreceptor and inhibition of diverse enveloped viruses. J Virol (2000) 1.26

Antireplicative and anticytopathic activities of prostratin, a non-tumor-promoting phorbol ester, against human immunodeficiency virus (HIV). Antiviral Res (1997) 1.26

Crystal structure of Escherichia coli HdeA. Nat Struct Biol (1998) 1.25

Oxathiin carboxanilide, a potent inhibitor of human immunodeficiency virus reproduction. Proc Natl Acad Sci U S A (1991) 1.24

Antineoplastic agents. 379. Synthesis of phenstatin phosphate. J Med Chem (1998) 1.23

Flexible alignment of small molecules. J Med Chem (2001) 1.22

A semiautomated multiparameter approach for anti-HIV drug screening. J Virol Methods (1991) 1.21

HIV inhibitory natural products. 26. Quinoline alkaloids from Euodia roxburghiana. J Nat Prod (1996) 1.19

HIV-inhibitory cembrane derivatives from a Philippines collection of the soft coral Lobophytum species. J Nat Prod (2000) 1.18

Acute pulmonary injury in rats by nitrofurantoin and modification by vitamin E, dietary fat, and oxygen. Am Rev Respir Dis (1979) 1.18

Penciclovir is a selective inhibitor of hepatitis B virus replication in cultured human hepatoblastoma cells. Antimicrob Agents Chemother (1996) 1.17

Hepatitis C virus kinetics. Antivir Ther (2000) 1.15

Lack of correlation between natural killer activity and tumor growth control in nude mice with different immune defects. Cancer Res (1984) 1.15

Flavone-8-acetic acid augments systemic natural killer cell activity and synergizes with IL-2 for treatment of murine renal cancer. J Immunol (1988) 1.15

Comparative anti-HIV evaluation of diverse HIV-1-specific reverse transcriptase inhibitor-resistant virus isolates demonstrates the existence of distinct phenotypic subgroups. Antiviral Res (1995) 1.14

Antineoplastic agents. 450. Synthesis of (+)-pancratistatin from (+)-narciclasine as relay(1a). J Org Chem (2001) 1.14

Profiles of prostaglandin biosynthesis in normal lung and tumor tissue from lung cancer patients. Cancer Res (1988) 1.13

AIDS-antiviral sulfolipids from cyanobacteria (blue-green algae). J Natl Cancer Inst (1989) 1.12

Progress in the discovery of biosynthetic anticancer drugs. J Nat Prod (1996) 1.11

Thiazolinone analogues of indolmycin with antiviral and antibacterial activity. J Med Chem (1978) 1.10

A chemical screening strategy for the dereplication and prioritization of HIV-inhibitory aqueous natural products extracts. J Nat Prod (1993) 1.10

Multidrug-resistant phenotype of disease-oriented panels of human tumor cell lines used for anticancer drug screening. Cancer Res (1992) 1.10

Antineoplastic agents 430. Isolation and structure of cribrostatins 3, 4, and 5 from the republic of maldives cribrochalina species. J Nat Prod (2000) 1.10

Guttiferone F, the first prenylated benzophenone from Allanblackia stuhlmannii. J Nat Prod (1999) 1.09

Analysis of the interaction between the HIV-inactivating protein cyanovirin-N and soluble forms of the envelope glycoproteins gp120 and gp41. Mol Pharmacol (2000) 1.09

Antineoplastic agents, 120. Pancratium littorale. J Nat Prod (1987) 1.07

Caulobacter crescentus mutants with short stalks. J Bacteriol (1969) 1.07

Siamenol, a new carbazole alkaloid from Murraya siamensis. J Nat Prod (2000) 1.07

Antineoplastic agents. 398. Isolation and structure elucidation of cephalostatins 18 and 19. J Nat Prod (1998) 1.06

Haligramides A and B, two new cytotoxic hexapeptides from the marine sponge Haliclona nigra. J Nat Prod (2000) 1.05

A pentahalogenated monoterpene from the red alga Portieria hornemannii produces a novel cytotoxicity profile against a diverse panel of human tumor cell lines. J Med Chem (1992) 1.05

Antineoplastic agents 365. Dolastatin 10 SAR probes. Anticancer Drug Des (1998) 1.04

Studies directed towards the refinement of the pancratistatin cytotoxic pharmacophore. Bioorg Med Chem Lett (2001) 1.04

Prodrugs of the selective antiherpesvirus agent 9-[4-hydroxy-3-(hydroxymethyl)but-1-yl]guanine (BRL 39123) with improved gastrointestinal absorption properties. J Med Chem (1989) 1.03

Antineoplastic agents. 340. Isolation and structural elucidation of bryostatins 16-18. J Nat Prod (1996) 1.03

Morphometric and colorimetric analyses of human tumor cell line growth and drug sensitivity in soft agar culture. Cancer Res (1991) 1.03

Ethnobotany and drug discovery: the experience of the US National Cancer Institute. Ciba Found Symp (1994) 1.03

Antineoplastic agents. 278. Isolation and structure of axinastatins 2 and 3 from a western Caroline Island marine sponge. J Med Chem (1994) 1.03

Activity of mitozolomide (NSC 353451), a new imidazotetrazine, against xenografts from human melanomas, sarcomas, and lung and colon carcinomas. Cancer Res (1985) 1.03

In vitro metabolic activation of the pulmonary toxin, 4-ipomeanol, in nonciliated bronchiolar epithelial (Clara) and alveolar type II cells isolated from rabbit lung. J Pharmacol Exp Ther (1982) 1.03

Biochemical mechanisms in chemical-induced lung injury: roles of metabolic activation. Crit Rev Toxicol (1980) 1.02

Solution structure by NMR of circulin A: a macrocyclic knotted peptide having anti-HIV activity. J Mol Biol (1999) 1.02

Recombinant production of cyanovirin-N, a potent human immunodeficiency virus-inactivating protein derived from a cultured cyanobacterium. Protein Expr Purif (1998) 1.02

Specific inhibition of the reverse transcriptase of human immunodeficiency virus type 1 and the chimeric enzymes of human immunodeficiency virus type 1 and type 2 by nonnucleoside inhibitors. Antimicrob Agents Chemother (1993) 1.01

Confirmation by chemical synthesis of the structure of 4-ipomeanol, a lung-toxic metabolite of the sweet potato, Ipomoea batatas. Nat New Biol (1972) 1.01

Chloroperoxidase. IX. The structure of compound I. J Am Chem Soc (1972) 1.01

Anti-HIV prenylated flavonoids from Monotes africanus. J Nat Prod (2001) 1.00

Conformational backbone dynamics of the cyclic decapeptide antamanide. Application of a new multiconformational search algorithm based on NMR data. Biochemistry (1993) 1.00