Published in Ophthalmology on February 01, 1997
A common haplotype in the complement regulatory gene factor H (HF1/CFH) predisposes individuals to age-related macular degeneration. Proc Natl Acad Sci U S A (2005) 13.44
Age-related macular degeneration. Lancet (2008) 3.34
Age-related macular degeneration--emerging pathogenetic and therapeutic concepts. Ann Med (2006) 2.99
Early drusen formation in the normal and aging eye and their relation to age related maculopathy: a clinicopathological study. Br J Ophthalmol (1999) 1.54
Prevalence and morphology of druse types in the macula and periphery of eyes with age-related maculopathy. Invest Ophthalmol Vis Sci (2008) 1.24
Age-related macular degeneration in the aspect of chronic low-grade inflammation (pathophysiological parainflammation). Mediators Inflamm (2014) 1.20
Identification of lesion components that influence visual function in age related macular degeneration. Br J Ophthalmol (2003) 1.12
Assessment of multifocal electroretinogram abnormalities and their relation to morphologic characteristics in patients with large drusen. Arch Ophthalmol (2003) 1.08
Progress in defining the molecular biology of age related macular degeneration. Hum Genet (2007) 1.01
The APO(*)E3-Leiden mouse as an animal model for basal laminar deposit. Br J Ophthalmol (2000) 0.99
Microstructure of subretinal drusenoid deposits revealed by adaptive optics imaging. Biomed Opt Express (2014) 0.90
Innate immune network in the retina activated by optic nerve crush. Invest Ophthalmol Vis Sci (2013) 0.88
Age-related macular degeneration and changes in the extracellular matrix. Med Sci Monit (2014) 0.88
Glycoproteins of drusen and drusen-like lesions. J Mol Histol (2007) 0.79
Comparison of lectin binding of drusen, RPE, Bruch's membrane, and photoreceptors. Mol Vis (2009) 0.78
An integrated hypothesis that considers drusen as biomarkers of immune-mediated processes at the RPE-Bruch's membrane interface in aging and age-related macular degeneration. Prog Retin Eye Res (2001) 8.38
Localization of mitochondria in living cells with rhodamine 123. Proc Natl Acad Sci U S A (1980) 7.31
Complement activation and inflammatory processes in Drusen formation and age related macular degeneration. Exp Eye Res (2001) 4.38
Monitoring of relative mitochondrial membrane potential in living cells by fluorescence microscopy. J Cell Biol (1981) 3.97
A single EFEMP1 mutation associated with both Malattia Leventinese and Doyne honeycomb retinal dystrophy. Nat Genet (1999) 3.32
Variations in the complement regulatory genes factor H (CFH) and factor H related 5 (CFHR5) are associated with membranoproliferative glomerulonephritis type II (dense deposit disease). J Med Genet (2005) 2.92
Structure and composition of drusen associated with glomerulonephritis: implications for the role of complement activation in drusen biogenesis. Eye (Lond) (2001) 2.85
PEDF: a pigment epithelium-derived factor with potent neuronal differentiative activity. Exp Eye Res (1991) 2.71
A potential role for immune complex pathogenesis in drusen formation. Exp Eye Res (2000) 2.58
Disc morphogenesis in vertebrate photoreceptors. J Comp Neurol (1980) 2.57
Mutations in the novel protocadherin PCDH15 cause Usher syndrome type 1F. Hum Mol Genet (2001) 2.48
Location, substructure, and composition of basal laminar drusen compared with drusen associated with aging and age-related macular degeneration. Am J Ophthalmol (2000) 2.27
Pigment epithelium-derived factor: neurotrophic activity and identification as a member of the serine protease inhibitor gene family. Proc Natl Acad Sci U S A (1993) 2.15
Vitronectin is a constituent of ocular drusen and the vitronectin gene is expressed in human retinal pigmented epithelial cells. FASEB J (1999) 2.00
Apolipoprotein E allele-dependent pathogenesis: a model for age-related retinal degeneration. Proc Natl Acad Sci U S A (2005) 1.92
Renewal of the terminal bronchiolar epithelium in the rat following exposure to NO2 or O3. Lab Invest (1976) 1.85
Morphological recovery in the reattached retina. Invest Ophthalmol Vis Sci (1986) 1.79
Autosomal dominant Stargardt-like macular dystrophy: founder effect and reassessment of genetic heterogeneity. Arch Ophthalmol (2001) 1.65
Local cellular sources of apolipoprotein E in the human retina and retinal pigmented epithelium: implications for the process of drusen formation. Am J Ophthalmol (2001) 1.64
Neuronal differentiation of retinoblastoma cells induced by medium conditioned by human RPE cells. Invest Ophthalmol Vis Sci (1989) 1.63
Individuals homozygous for the age-related macular degeneration risk-conferring variant of complement factor H have elevated levels of CRP in the choroid. Proc Natl Acad Sci U S A (2006) 1.63
Retinal degeneration 6 (rd6): a new mouse model for human retinitis punctata albescens. Invest Ophthalmol Vis Sci (2000) 1.61
The TB structural genomics consortium: a resource for Mycobacterium tuberculosis biology. Tuberculosis (Edinb) (2003) 1.55
Expression, secretion, and age-related downregulation of pigment epithelium-derived factor, a serpin with neurotrophic activity. J Neurosci (1995) 1.55
Laccase-mediated detoxification of phenolic compounds. Appl Environ Microbiol (1988) 1.55
Molecular genetics of age-related macular degeneration. Hum Mol Genet (2001) 1.55
Specific binding of peanut lectin to a class of retinal photoreceptor cells. A species comparison. Invest Ophthalmol Vis Sci (1984) 1.53
Selective lectin binding of the developing mouse retina. J Comp Neurol (1983) 1.52
Mammalian cones: disc shedding, phagocytosis, and renewal. Invest Ophthalmol Vis Sci (1978) 1.50
The interphotoreceptor matrix mediates primate retinal adhesion. Arch Ophthalmol (1995) 1.49
Probing mitochondria in living cells with rhodamine 123. Cold Spring Harb Symp Quant Biol (1982) 1.46
Retinal detachment in the cat: the outer nuclear and outer plexiform layers. Invest Ophthalmol Vis Sci (1983) 1.45
Crystal structure of alpha 1: implications for protein design. Science (1990) 1.44
Complete sequence and organization of the human cardiac beta-myosin heavy chain gene. Nucleic Acids Res (1990) 1.42
Retinal detachment in the cat: the pigment epithelial-photoreceptor interface. Invest Ophthalmol Vis Sci (1983) 1.33
Mouse model for Usher syndrome: linkage mapping suggests homology to Usher type I reported at human chromosome 11p15. Proc Natl Acad Sci U S A (1995) 1.33
Application of acrylamide as an embedding medium in studies of lectin and antibody binding in the vertebrate retina. Curr Eye Res (1984) 1.26
The onset of pigment epithelial proliferation after retinal detachment. Invest Ophthalmol Vis Sci (1981) 1.26
Intraretinal proliferation induced by retinal detachment. Invest Ophthalmol Vis Sci (1991) 1.21
Vitronectin receptor expression and distribution at the photoreceptor-retinal pigment epithelial interface. J Comp Neurol (1995) 1.21
Anomie and alcohol use. Drinking patterns in Mexican American and Anglo neighborhoods. J Stud Alcohol (1978) 1.20
Glial fibrillary acidic protein increases in Müller cells after retinal detachment. Exp Eye Res (1987) 1.17
Transmembrane assemblage of the photoreceptor connecting cilium and motile cilium transition zone contain a common immunologic epitope. Cell Motil Cytoskeleton (1990) 1.17
Molecular cloning and expression of a MAP kinase homologue from pea. Plant Mol Biol (1993) 1.15
Rapid changes in the expression of glial cell proteins caused by experimental retinal detachment. Am J Ophthalmol (1994) 1.13
Centrosymmetric bilayers in the 0.75 A resolution structure of a designed alpha-helical peptide, D,L-Alpha-1. Protein Sci (1999) 1.11
Interphotoreceptor matrix domains ensheath vertebrate cone photoreceptor cells. Invest Ophthalmol Vis Sci (1986) 1.10
Transforming growth factor beta 2 is the predominant isoform in the neural retina, retinal pigment epithelium-choroid and vitreous of the monkey eye. Exp Eye Res (1994) 1.10
The relationship of primate foveal cones to the pigment epithelium. J Ultrastruct Res (1979) 1.10
Vascular atrophy in the retinal degenerative rd mouse. J Comp Neurol (1986) 1.10
The genetics of age-related macular degeneration. Mol Vis (1999) 1.09
Pulmonary lesions due to opportunist mycobacteria. (Review includes 30 cases of M. kansasii infections). Clin Radiol (1975) 1.06
Optic disc, foveal, and extrafoveal damage due to surgical separation of the vitreous. Arch Ophthalmol (2001) 1.05
Changes in the expression of specific Müller cell proteins during long-term retinal detachment. Exp Eye Res (1989) 1.05
Recovery of photoreceptor outer segment length and analysis of membrane assembly rates in regenerating primate photoreceptor outer segments. Invest Ophthalmol Vis Sci (1993) 1.04
Retinal adhesiveness is weakened by enzymatic modification of the interphotoreceptor matrix in vivo. Invest Ophthalmol Vis Sci (1990) 1.02
A cooperative model for receptor recognition and cell adhesion: evidence from the molecular packing in the 1.6-A crystal structure of the pheromone Er-1 from the ciliated protozoan Euplotes raikovi. Proc Natl Acad Sci U S A (1995) 1.01
Rod and cone disc shedding in the rhesus monkey retina: a quantitative study. Exp Eye Res (1980) 1.00
Xyloside-induced disruption of interphotoreceptor matrix proteoglycans results in retinal detachment. Invest Ophthalmol Vis Sci (1992) 0.99
Both rod and cone disc shedding are related to light onset in the cat. Invest Ophthalmol Vis Sci (1983) 0.98
Decreased uptake and retention of rhodamine 123 by mitochondria in feline sarcoma virus-transformed mink cells. Cell (1982) 0.97
Use of the MIB-1 antibody for detecting proliferating cells in the retina. Invest Ophthalmol Vis Sci (1995) 0.97
Genomic organization and mutation analysis of the gene encoding lecithin retinol acyltransferase in human retinal pigment epithelium. Invest Ophthalmol Vis Sci (2001) 0.97
Interfaces. Eur J Ophthalmol (2000) 0.97
Basic fibroblast growth factor: a potential regulator of proliferation and intermediate filament expression in the retina. J Neurosci (1992) 0.97
In situ characterization of the human hyalocyte. Arch Ophthalmol (1994) 0.96
Cell renewal in the lungs of rats exposed to low levels of ozone. Exp Mol Pathol (1976) 0.96
Crystal structure of phospholipase A2 from Indian cobra reveals a trimeric association. Proc Natl Acad Sci U S A (1993) 0.96
Distribution of glycoconjugates in the human retinal internal limiting membrane. Invest Ophthalmol Vis Sci (1991) 0.94
Sequestration of basic fibroblast growth factor in the primate retinal interphotoreceptor matrix. Proc Natl Acad Sci U S A (1991) 0.94
The photoreceptors of diurnal squirrels: outer segment structure, disc shedding, and protein renewal. J Ultrastruct Res (1976) 0.93
Human ocular drusen possess novel core domains with a distinct carbohydrate composition. J Histochem Cytochem (1999) 0.93
Neurotrophic activity of interphotoreceptor matrix on human Y79 retinoblastoma cells. J Comp Neurol (1992) 0.93
Characterization of glucose transporter isoforms in the adult and developing human eye. Endocrinology (1993) 0.91
Biochemical characterization of the major peanut-agglutinin-binding glycoproteins in vertebrate retinae. J Comp Neurol (1986) 0.91
Retinal degeneration in motor neuron degeneration: a mouse model of ceroid lipofuscinosis. Invest Ophthalmol Vis Sci (1994) 0.90
Disc shedding in rodlike and conelike photoreceptors of tree squirrels. Science (1975) 0.89
Packed protein bilayers in the 0.90 A resolution structure of a designed alpha helical bundle. Protein Sci (1999) 0.89
Selective sequestration of an oviductal fluid glycoprotein in the perivitelline space of mouse oocytes and embryos. J Exp Zool (1986) 0.89
Ocular toxicity of fluorouracil after vitrectomy. Am J Ophthalmol (1983) 0.89
Stage-specific binding of peanut agglutinin to aggregates of degenerating photoreceptor cells in the rd mouse retina. Exp Eye Res (1993) 0.89
Expression of the glaucoma gene myocilin (MYOC) in the human optic nerve head. FASEB J (2001) 0.89
Scotopic and photopic vision in the California ground squirrel: physiological and anatomical evidence. J Comp Neurol (1976) 0.89
Changes in intermediate filament immunolabeling occur in response to retinal detachment and reattachment in primates. Invest Ophthalmol Vis Sci (1990) 0.89
Vitronectin gene expression in the adult human retina. Invest Ophthalmol Vis Sci (1999) 0.89
Photoreceptor degeneration and altered distribution of interphotoreceptor matrix proteoglycans in the mucopolysaccharidosis VII mouse. Exp Eye Res (1993) 0.88
Fluorouracil therapy for proliferative vitreoretinopathy after vitrectomy. Am J Ophthalmol (1983) 0.88
Opsin distribution and protein incorporation in photoreceptors after experimental retinal detachment. Exp Eye Res (1991) 0.88