L Cusan

Author PubWeight™ 64.53‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Screening decreases prostate cancer death: first analysis of the 1988 Quebec prospective randomized controlled trial. Prostate 1999 4.12
2 The impact of family history on early detection of prostate cancer. Nat Med 1995 2.14
3 Beneficial effect of combination hormonal therapy administered prior and following external beam radiation therapy in localized prostate cancer. Int J Radiat Oncol Biol Phys 1997 2.10
4 Marked decline in serum concentrations of adrenal C19 sex steroid precursors and conjugated androgen metabolites during aging. J Clin Endocrinol Metab 1997 1.96
5 Serum prostate specific antigen as pre-screening test for prostate cancer. J Urol 1992 1.84
6 Changes in serum concentrations of conjugated and unconjugated steroids in 40- to 80-year-old men. J Clin Endocrinol Metab 1994 1.66
7 New hormonal therapy in prostatic carcinoma: combined treatment with an LHRH agonist and an antiandrogen. Clin Invest Med 1982 1.65
8 Diagnosis of advanced or noncurable prostate cancer can be practically eliminated by prostate-specific antigen. Urology 1996 1.56
9 Incidence of liver toxicity associated with the use of flutamide in prostate cancer patients. Am J Med 1992 1.50
10 Important prognostic value of standardized objective criteria of response in stage D2 prostatic carcinoma. Eur J Cancer Clin Oncol 1988 1.38
11 DHEA and the intracrine formation of androgens and estrogens in peripheral target tissues: its role during aging. Steroids 1998 1.35
12 Comparison of residual C-19 steroids in plasma and prostatic tissue of human, rat and guinea pig after castration: unique importance of extratesticular androgens in men. J Steroid Biochem 1989 1.18
13 Physiological changes in dehydroepiandrosterone are not reflected by serum levels of active androgens and estrogens but of their metabolites: intracrinology. J Clin Endocrinol Metab 1997 1.10
14 Effect of neoadjuvant endocrine therapy (combined androgen blockade) on normal prostate and prostatic carcinoma. A randomized study. Am J Surg Pathol 1996 1.08
15 Effect of 12-month dehydroepiandrosterone replacement therapy on bone, vagina, and endometrium in postmenopausal women. J Clin Endocrinol Metab 1997 1.02
16 Prolonged neoadjuvant combined androgen blockade leads to a further reduction of prostatic tumor volume: three versus six months of endocrine therapy. Urology 1999 1.00
17 Evaluation of prostatic specific antigen and digital rectal examination as screening tests for prostate cancer. Prostate 2000 0.99
18 Downstaging of localized prostate cancer by neoadjuvant therapy with flutamide and lupron: the first controlled and randomized trial. Clin Invest Med 1993 0.96
19 EM-652 (SCH 57068), a third generation SERM acting as pure antiestrogen in the mammary gland and endometrium. J Steroid Biochem Mol Biol 1999 0.94
20 Response to flutamide withdrawal in advanced prostate cancer in progression under combination therapy. J Urol 1993 0.92
21 Metabolic effects of 12-month percutaneous dehydroepiandrosterone replacement therapy in postmenopausal women. J Endocrinol 1996 0.89
22 Inhibition of spermatogenesis in the rat by treatment with [D-Ala6, Des-Gly-NH210] LHRH ethylamide. Endocrinology 1978 0.89
23 Beta-endorphin: stimulation of growth hormone release in vivo. Proc Natl Acad Sci U S A 1977 0.89
24 Cellular localization of the Mn2+-dependent adenylyl cyclase in the human testis. Arch Androl 1982 0.87
25 Intravaginal dehydroepiandrosterone (prasterone), a highly efficient treatment of dyspareunia. Climacteric 2011 0.86
26 Neoadjuvant hormonal therapy: the Canadian experience. Urology 1997 0.85
27 Inhibitory effects of long term treatment with a luteinizing hormone-releasing hormone agonist on the pituitary-gonadal axis in male and female rats. Endocrinology 1979 0.85
28 Additive inhibitory effects of treatment with an LHRH agonist and an antiandrogen on androgen-dependent tissues in the rat. Mol Cell Endocrinol 1981 0.85
29 Optimized strategy for detection of early stage, curable prostate cancer: role of prescreening with prostate-specific antigen. Clin Invest Med 1993 0.84
30 Potent prolactin and growth hormone releasing activity of more analogues of Met-enkephalin. Nature 1977 0.84
31 Influence of diet on plasma steroids and sex hormone-binding globulin levels in adult men. J Steroid Biochem 1989 0.84
32 Analysis of the androgenic activity of synthetic "progestins" currently used for the treatment of prostate cancer. J Steroid Biochem 1987 0.82
33 Steroid glucuronides: human circulatory levels and formation by LNCaP cells. J Steroid Biochem Mol Biol 1991 0.82
34 Bioavailability and metabolism of oral and percutaneous dehydroepiandrosterone in postmenopausal women. J Steroid Biochem Mol Biol 2007 0.81
35 [Validation of a French adaptation of the international prostatic symptom score]. Prog Urol 1996 0.80
36 Simultaneous liver and lung toxicity related to the nonsteroidal antiandrogen nilutamide (Anandron): a case report. Am J Med 1992 0.80
37 Plasma levels of hydroxy-flutamide in patients with prostatic cancer receiving the combined hormonal therapy: an LHRH agonist and flutamide. Prostate 1988 0.80
38 Ovarian progestins, androgens and estrogen throughout the 4-day estrous cycle in the rat. Biol Reprod 1981 0.80
39 Changes in plasma lipoproteins during various androgen suppression therapies in men with prostatic carcinoma: effects of orchiectomy, estrogen, and combination treatment with luteinizing hormone-releasing hormone agonist and flutamide. J Clin Endocrinol Metab 1988 0.80
40 Extremely rapid degradation of [3H] methionine-enkephalin by various rat tissues in vivo and in vitro. Life Sci 1977 0.80
41 Downstaging by combination therapy with flutamide and an LHRH agonist before radical prostatectomy. Cancer Surv 1995 0.79
42 Hormonal and biochemical changes during treatment of endometriosis with the luteinizing hormone-releasing hormone (LH-RH) agonist [D-Trp6,des-Gly-NH2(10)]LH-RH ethylamide. Fertil Steril 1990 0.79
43 Combination therapy with flutamide and the LHRH agonist [D-Trp6, des-Gly-NH(2)10]LHRH ethylamide in stage C prostatic carcinoma. Br J Urol 1993 0.78
44 Characterization of protein carboxyl methylase activities in rat testis: presence of testis specific charge isomers. Arch Androl 1981 0.78
45 Anti-hormone treatment for prostate cancer relapsing after treatment with flutamide and castration. Addition of aminoglutethimide and low dose hydrocortisone to combination therapy. Br J Urol 1989 0.78
46 Antifertility effects of LHRH agonists in the male rat and inhibition of testicular steroidogenesis in man. Int J Fertil 1980 0.78
47 Effects of flutamide and aminoglutethimide on plasma 5 alpha-reduced steroid glucuronide concentrations in castrated patients with cancer of the prostate. J Steroid Biochem 1987 0.77
48 Inhibitory effects of treatment with LHRH or its agonists on ovarian receptor levels and function. Adv Exp Med Biol 1979 0.77
49 New hormonal therapy in prostate cancer: combined use of a pure antiandrogen and an LHRH agonist. Horm Res 1983 0.77
50 Inhibition of ovarian luteinizing hormone (LH) and follicle-stimulating hormone receptor levels with an LH-releasing hormone agonist during the estrous cycle in the rat. Fertil Steril 1978 0.77
51 Stratification of stage D2 prostate cancer patients by a disease aggressiveness score and its use in evaluating disease response and outcome to combination hormonal treatment (GnRH-A plus flutamide). Anticancer Res 1994 0.77
52 Inhibitory effect of a luteinizing hormone (LH)-releasing hormone agonist on rat ovarian LH and follicle-stimulating hormone receptor levels during pregnancy. Fertil Steril 1978 0.77
53 Impairment of pituitary and gonadal functions in alloxan-induced diabetic male rats. Mol Cell Endocrinol 1980 0.77
54 Androgen receptor modulation in benign human prostatic tissue and prostatic adenocarcinoma during neoadjuvant endocrine combination therapy. Prostate 1996 0.77
55 Combination therapy with castration and flutamide: today's treatment of choice for prostate cancer. J Steroid Biochem 1989 0.76
56 Rat sperm enzymes during epididymal transit. J Reprod Fertil 1982 0.76
57 Combination therapy with flutamide and [D-Trp6]LHRH ethylamide for stage C prostatic carcinoma. Eur J Cancer Clin Oncol 1988 0.76
58 beta-Endorphin and met-enkephalins: their distribution, modulation by estrogens and haloperidol, and role in neuroendocrine control. Fed Proc 1980 0.76
59 Relative importance of the adenohypophyseal and gonadal sites in inhibitory action of LHRH agonists. Biol Reprod 1981 0.76
60 Stimulation of prolactin release in the rat by intraventricular injection of beta-endorphin and methionine-enkephalin. Biochem Biophys Res Commun 1977 0.76
61 Effect of an LHRH analog on growth and hormone receptor levels in DMBA-induced mammary tumors in the rat. J Recept Res 1981 0.76
62 Complete response to combination therapy with an LHRH agonist and flutamide in metastatic male breast cancer: a case report. Clin Invest Med 1990 0.76
63 Combination therapy with flutamide and castration (LHRH agonist or orchiectomy) in previously untreated patients with clinical stage D2 prostate cancer: today's therapy of choice. J Steroid Biochem 1988 0.76
64 Combination therapy with flutamide and castration: its benefits at various stages of prostate cancer. Prog Clin Biol Res 1989 0.75
65 Adenylyl cyclase and protein carboxyl methylase in human spermatozoa. Arch Androl 1982 0.75
66 Changes in plasma lipoprotein and apolipoprotein composition in relation to oral versus percutaneous administration of estrogen alone or in cyclic association with utrogestan in menopausal women. J Clin Endocrinol Metab 1991 0.75
67 Prostate specific antigen and prostatic acid phosphatase for monitoring therapy of carcinoma of the prostate. J Urol 1991 0.75
68 Increased testicular 5 alpha-androstane-3 alpha, 17 beta-diol formation induced by treatment with [D-Ser (TBU) 6, des-Gly-NH2(10)] LHRH ethylamide in the rat. Steroids 1980 0.75
69 New hormonal treatment in cancer of the prostate: combined administration of an LHRH agonist and an antiandrogen. J Steroid Biochem 1983 0.75
70 [Inhibition of testicular steroidogenesis in the rat following administration of an LHRH agonist]. Union Med Can 1980 0.75
71 Combination therapy in stage C and D prostatic cancer: rationale and five year clinical experience. Cancer Metastasis Rev 1987 0.75
72 [Inhibition of gonadal function by LHRH and their agonists in the male and female rat]. Union Med Can 1978 0.75
73 Contraception with LHRH agonists, a new physiological approach. Reproduccion 1982 0.75
74 Physiological role of endorphins in neuroendocrinology. Acta Physiol Pol 1981 0.75
75 Octreotide and bromocriptine in patients with stage D2 prostate cancer who relapsed during treatment with flutamide and castration. Eur J Cancer 1990 0.75
76 Combination therapy with flutamide and castration (orchiectomy or LH-RH agonist) in untreated patients with advanced prostate cancer. Recent Results Cancer Res 1992 0.75
77 Effects of castration, sex steroids, LHRH and glucocorticoids on LHRH binding in the anterior pituitary of male rats. Int J Androl 1981 0.75
78 Antifertility effects of luteinizing hormone-releasing hormone (LHRH) agonists. Prog Clin Biol Res 1981 0.75
79 [Total androgen blockade: an argument in favor]. Union Med Can 1989 0.75
80 Regulation of steroidogenesis and steroid action in Leydig cells. J Steroid Biochem 1981 0.75
81 Evidence for a role of endorphins in stress- and suckling-induced prolactin release in the rat. Mol Cell Endocrinol 1978 0.75
82 Protein carboxylmethylase and germ cell adenylyl cyclase at specific stages of the spermatogenic cycle of the rat. Biol Reprod 1981 0.75
83 Combination of screening and preoperative endocrine therapy: the potential for an important decrease in prostate cancer mortality. J Clin Endocrinol Metab 1995 0.75
84 Combination therapy with flutamide and medical (LHRH agonist) or surgical castration in advanced prostate cancer: 7-year clinical experience. J Steroid Biochem Mol Biol 1990 0.75
85 Endocrine effects of combined treatment with an LHRH agonist in association with flutamide in metastatic prostatic carcinoma. Clin Invest Med 1988 0.75
86 Major advantages of "early" administration of endocrine combination therapy in advanced prostate cancer. Clin Invest Med 1993 0.75
87 [Inhibitory effects of LHRH on LH receptors in the rat testis]. C R Acad Sci Hebd Seances Acad Sci D 1978 0.75
88 Combination therapy with flutamide and [D-Trp6, des-Gly-NH2(10)]LHRH ethylamide in stage C and D prostate cancer: today's therapy of choice--rationale and 5-year clinical experience. Prog Clin Biol Res 1988 0.75
89 Stimulatory effect of luteinizing hormone and human chorionic gonadotropin on testicular prolactin receptor levels. Biol Reprod 1980 0.75
90 Effect of an LHRH agonist and hCG on testicular steroidogenesis in the adult rat. Biol Reprod 1980 0.75
91 Desensitization of FSH-responsive adenylyl cyclase in cultured immature Sertoli cells by homologous hormone. Arch Androl 1982 0.75
92 Comparative endocrinological and clinical effects of percutaneous estradiol and oral conjugated estrogens as replacement therapy in menopausal women. Maturitas 1991 0.75
93 Changes in protein carboxyl-methylase isoenzymes during testicular development in the rat. Arch Androl 1982 0.75