PubRank

W J van Blitterswijk

Author PubWeight™ 59.41‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Mitogenic action of lysophosphatidic acid and phosphatidic acid on fibroblasts. Dependence on acyl-chain length and inhibition by suramin. Biochem J 1992 2.10
2 Identification of a putative membrane receptor for the bioactive phospholipid, lysophosphatidic acid. EMBO J 1992 1.97
3 A dominant-negative mutant of raf blocks mitogen-activated protein kinase activation by growth factors and oncogenic p21ras. J Biol Chem 1993 1.74
4 Phosphatidic acid activation of protein kinase C-zeta overexpressed in COS cells: comparison with other protein kinase C isotypes and other acidic lipids. Biochem J 1994 1.64
5 Purification, cDNA-cloning and expression of human diacylglycerol kinase. FEBS Lett 1990 1.45
6 Sphingomyelin hydrolysis to ceramide during the execution phase of apoptosis results from phospholipid scrambling and alters cell-surface morphology. J Cell Biol 2000 1.38
7 The human MDR3 P-glycoprotein promotes translocation of phosphatidylcholine through the plasma membrane of fibroblasts from transgenic mice. FEBS Lett 1994 1.34
8 The biologically active phospholipid, lysophosphatidic acid, induces phosphatidylcholine breakdown in fibroblasts via activation of phospholipase D. Comparison with the response to endothelin. Biochem J 1992 1.33
9 Protein kinase Czeta is a negative regulator of protein kinase B activity. J Biol Chem 1999 1.29
10 Isolation of plasma membranes from rat and mouse livers and hepatomas. Methods Enzymol 1974 1.26
11 Lysophosphatidic acid-induced Ca2+ mobilization in human A431 cells: structure-activity analysis. Biochem J 1995 1.26
12 Quantitative contributions of cholesterol and the individual classes of phospholipids and their degree of fatty acyl (un)saturation to membrane fluidity measured by fluorescence polarization. Biochemistry 1987 1.25
13 1-O-hexadecyl-2-Q-methylglycerol, a novel inhibitor of protein kinase C, inhibits the respiratory burst in human neutrophils. J Biol Chem 1989 1.24
14 Diacylglycerol kinase is phosphorylated in vivo upon stimulation of the epidermal growth factor receptor and serine/threonine kinases, including protein kinase C-epsilon. Biochem J 1993 1.20
15 Ordering of ceramide formation, caspase activation, and mitochondrial changes during CD95- and DNA damage-induced apoptosis. J Clin Invest 1999 1.19
16 Alkyl-lysophospholipids activate the SAPK/JNK pathway and enhance radiation-induced apoptosis. Cancer Res 1999 1.18
17 Common regulation of apoptosis signaling induced by CD95 and the DNA-damaging stimuli etoposide and gamma-radiation downstream from caspase-8 activation. J Biol Chem 1999 1.10
18 Metabolic conversion of the biologically active phospholipid, lysophosphatidic acid, in fibroblasts. Biochim Biophys Acta 1992 1.08
19 Diacylglycerol kinase theta binds to and is negatively regulated by active RhoA. J Biol Chem 1999 1.08
20 Immunologic, virologic, and genetic aspects of mammary tumor virus-induced cell-surface antigens: presence of these antigens and the Thy 1.2 antigen on murine mammary gland and tumor cells. J Natl Cancer Inst 1975 1.08
21 Involvement of phosphatidylcholine-specific phospholipase C in platelet-derived growth factor-induced activation of the mitogen-activated protein kinase pathway in Rat-1 fibroblasts. J Biol Chem 1997 1.07
22 Cloning of a novel human diacylglycerol kinase (DGKtheta) containing three cysteine-rich domains, a proline-rich region, and a pleckstrin homology domain with an overlapping Ras-associating domain. J Biol Chem 1997 1.05
23 CD95 (Fas/APO-1) induces ceramide formation and apoptosis in the absence of a functional acid sphingomyelinase. J Biol Chem 1998 1.04
24 Exogenous phospholipase D generates lysophosphatidic acid and activates Ras, Rho and Ca2+ signaling pathways. Curr Biol 1998 1.03
25 Changes in membrane lipid composition of human erythrocytes after dietary supplementation of (n-3) polyunsaturated fatty acids. Maintenance of membrane fluidity. Biochim Biophys Acta 1986 1.01
26 Diacylglycerol generated by exogenous phospholipase C activates the mitogen-activated protein kinase pathway independent of Ras- and phorbol ester-sensitive protein kinase C: dependence on protein kinase C-zeta. Biochem J 1997 1.01
27 Platelet-derived growth factor activation of mitogen-activated protein kinase depends on the sequential activation of phosphatidylcholine-specific phospholipase C, protein kinase C-zeta and Raf-1. Biochem J 1997 0.99
28 Diacylglycerol kinase-alpha phosphorylation by Src on Y335 is required for activation, membrane recruitment and Hgf-induced cell motility. Oncogene 2007 0.98
29 CD95/Fas-induced ceramide formation proceeds with slow kinetics and is not blocked by caspase-3/CPP32 inhibition. J Biol Chem 1997 0.97
30 Alkyl-lysophospholipids as anticancer agents and enhancers of radiation-induced apoptosis. Int J Radiat Oncol Biol Phys 2001 0.93
31 Rigid plasma-membrane-derived vesicles, enriched in tumour-associated surface antigens (MLr), occurring in the ascites fluid of a murine leukaemia (GRSL). Int J Cancer 1979 0.92
32 Negative regulation of diacylglycerol kinase theta mediates adenosine-dependent hepatocyte preconditioning. Cell Death Differ 2010 0.91
33 The role of the stress-activated protein kinase (SAPK/JNK) signaling pathway in radiation-induced apoptosis. Radiother Oncol 1998 0.91
34 Fluorescence polarization measurements on normal and tumour cells and their corresponding plasma membranes. Biochim Biophys Acta 1979 0.90
35 Diacylglycerol kinase theta is translocated and phosphoinositide 3-kinase-dependently activated by noradrenaline but not angiotensin II in intact small arteries. Biochem J 2001 0.89
36 Diacylglycerol kinase in receptor-stimulated cells converts its substrate in a topologically restricted manner. J Biol Chem 1994 0.89
37 Studies on plasma membranes. XIX. Isolation and characterization of a plasma membrane fraction from calf thymocytes. Biochim Biophys Acta 1973 0.88
38 Glucosylceramide synthase does not attenuate the ceramide pool accumulating during apoptosis induced by CD95 or anti-cancer regimens. J Biol Chem 2000 0.87
39 Lysophosphatidic acid: a novel phospholipid with hormone- and growth factor-like activities. Cold Spring Harb Symp Quant Biol 1992 0.87
40 Hypothesis: ceramide conditionally activates atypical protein kinases C, Raf-1 and KSR through binding to their cysteine-rich domains. Biochem J 1998 0.87
41 Differences in lipid fluidity among isolated plasma membranes of normal and leukemic lympocytes and membranes exfoliated from their cell surface. Biochim Biophys Acta 1977 0.87
42 Specificity of cysteine-rich domains in diacylglycerol kinases and protein kinases C. Biochem J 1998 0.86
43 Distribution and antibody-induced redistribution of a mammary tumor virus-induced and a normal antigen on the surface of mouse leukemia cells. J Natl Cancer Inst 1975 0.83
44 Effect of overexpression of a neutral sphingomyelinase on CD95-induced ceramide production and apoptosis. Biochem Biophys Res Commun 2001 0.83
45 Consensus sequences for ATP-binding sites in protein kinases do not apply to diacylglycerol kinases. Biochem J 1994 0.82
46 Antiinvasive effect of racemic 1-O-octadecyl-2-O-methylglycero-3-phosphocholine on MO4 mouse fibrosarcoma cells in vitro. Cancer Res 1985 0.81
47 Steady-state fluorescence polarization data in membranes. Resolution into physical parameters by an extended Perrin equation for restricted rotation of fluorophores. Biochim Biophys Acta 1986 0.80
48 Catalytic hydrogenation of fatty acyl chains in plasma membranes; effect on membrane lipid fluidity and expression of cell surface antigens. Biochim Biophys Acta 1987 0.79
49 N-hexanoyl-sphingomyelin potentiates in vitro doxorubicin cytotoxicity by enhancing its cellular influx. Br J Cancer 2004 0.79
50 Radiation-induced apoptosis--the ceramide-SAPK signaling pathway and clinical aspects. Acta Oncol 1998 0.78
51 Lipid metabolism in fibroblast growth factor-stimulated L6 myoblasts: a receptor mutation (Y766F) abrogates phospholipase D and diacylglycerol kinase activities. Biochim Biophys Acta 1998 0.78
52 Structural basis and physiological control of membrane fluidity in normal and tumor cells. Subcell Biochem 1988 0.78
53 New physiological functions for drug-transporting P-glycoproteins? Drug Resist Updat 1998 0.77
54 Alterations in biosynthesis and homeostasis of cholesterol and in lipoprotein patterns in mice bearing a transplanted lymphoid tumor. Biochim Biophys Acta 1985 0.77
55 Membrane organization determines barrier properties of endothelial cells and short-chain sphingolipid-facilitated doxorubicin influx. Biochim Biophys Acta 2014 0.76
56 Changes in concanavalin A-mediated agglutination of hormone-dependent mouse mammary tumour cells during serial transplantation. Br J Cancer 1980 0.75
57 Membrane fluidity, capping of cell-surface antigens and immune response in mouse leukaemia cells. Br J Cancer 1978 0.75
58 Accumulation of HDL-like lipoproteins in the plasma low-density fractions of tumor-bearing mice. Biochim Biophys Acta 1985 0.75
59 The composition of plasma lipoproteins and erythrocyte membranes in cholesterol-fed pigs with partial ileal bypass. Artery 1987 0.75