Published in Structure on April 15, 1997
Alkaliphiles: some applications of their products for biotechnology. Microbiol Mol Biol Rev (1999) 2.88
New methods of structure refinement for macromolecular structure determination by NMR. Proc Natl Acad Sci U S A (1998) 1.79
Structure and dynamics of coxsackievirus B4 2A proteinase, an enyzme involved in the etiology of heart disease. J Virol (2006) 1.00
Protein dynamics and motions in relation to their functions: several case studies and the underlying mechanisms. J Biomol Struct Dyn (2013) 0.83
Insights derived from molecular dynamics simulation into the molecular motions of serine protease proteinase K. J Mol Model (2009) 0.83
New binding site conformations of the dengue virus NS3 protease accessed by molecular dynamics simulation. PLoS One (2013) 0.81
Side chain dynamics monitored by 13C-13C cross-relaxation. J Biomol NMR (2004) 0.79
Structure of the unliganded form of the proprotein convertase furin suggests activation by a substrate-induced mechanism. Proc Natl Acad Sci U S A (2016) 0.78
The effect of calciums on molecular motions of proteinase K. J Mol Model (2010) 0.77
Unique chemotactic response profile and specific expression of chemokine receptors CCR4 and CCR8 by CD4(+)CD25(+) regulatory T cells. J Exp Med (2001) 5.56
Latent and active p53 are identical in conformation. Nat Struct Biol (2001) 3.47
Slow dynamics in folded and unfolded states of an SH3 domain. J Am Chem Soc (2001) 3.14
Structural and dynamic changes of photoactive yellow protein during its photocycle in solution. Nat Struct Biol (1998) 2.66
Solution structure of the glucocorticoid receptor DNA-binding domain. Science (1990) 2.64
The DNA-binding domain of HIV-1 integrase has an SH3-like fold. Nat Struct Biol (1995) 2.53
Altered flexibility in the substrate-binding site of related native and engineered high-alkaline Bacillus subtilisins. J Mol Biol (1999) 2.13
The C-C chemokine receptors CCR4 and CCR8 identify airway T cells of allergen-challenged atopic asthmatics. J Clin Invest (2001) 2.05
Sequential resonance assignments in 1H NMR spectra of oligonucleotides by two-dimensional NMR spectroscopy. Biochemistry (1984) 1.95
Structure of the complex of lac repressor headpiece and an 11 base-pair half-operator determined by nuclear magnetic resonance spectroscopy and restrained molecular dynamics. J Mol Biol (1993) 1.92
Thiol ester-linked p-coumaric acid as a new photoactive prosthetic group in a protein with rhodopsin-like photochemistry. Biochemistry (1994) 1.89
The structure of the translational initiation factor IF1 from E.coli contains an oligomer-binding motif. EMBO J (1997) 1.82
Structure of Arc repressor in solution: evidence for a family of beta-sheet DNA-binding proteins. Nature (1990) 1.80
Solution structure of the POU-specific DNA-binding domain of Oct-1. Nature (1993) 1.79
1H NMR study of the exchangeable protons of the duplex d(GCGTTGCG).d(CGCAACGC) containing a thymine photodimer. Nucleic Acids Res (1987) 1.78
Type 1 fiber abnormalities in skeletal muscle of patients with hypertrophic and dilated cardiomyopathy: evidence of subclinical myogenic myopathy. J Am Coll Cardiol (1989) 1.76
A protein structure from nuclear magnetic resonance data. lac repressor headpiece. J Mol Biol (1985) 1.62
Effects of abciximab on microvascular integrity and left ventricular functional recovery in patients with acute infarction treated by primary coronary angioplasty. Eur Heart J (2003) 1.58
Efficacy and safety of a combination of fluvastatin and bezafibrate in patients with mixed hyperlipidaemia (FACT study). Atherosclerosis (2000) 1.48
Blood pressure independent association of microalbuminuria and left ventricular hypertrophy in hypertensive men. J Intern Med (2003) 1.46
Coronary collateral circulation behaviour and myocardial viability in chronic total occlusion treated with coronary angioplasty. Eur Heart J (1998) 1.45
The solution structure of the amino-terminal HHCC domain of HIV-2 integrase: a three-helix bundle stabilized by zinc. Curr Biol (1997) 1.44
Polyglandular autoimmune syndrome type II and rheumatoid arthritis. Clin Exp Rheumatol (1997) 1.42
Solution structure of the LexA repressor DNA binding domain determined by 1H NMR spectroscopy. EMBO J (1994) 1.41
Probing slow time scale dynamics at methyl-containing side chains in proteins by relaxation dispersion NMR measurements: application to methionine residues in a cavity mutant of T4 lysozyme. J Am Chem Soc (2001) 1.40
Complex of lac repressor headpiece with a 14 base-pair lac operator fragment studied by two-dimensional nuclear magnetic resonance. J Mol Biol (1987) 1.39
Simple immunization protocol for high frequency production of soluble antigen-specific hybridomas. Hybridoma (1983) 1.33
EYA4, a novel vertebrate gene related to Drosophila eyes absent. Hum Mol Genet (1999) 1.32
Chemokines and their receptors guiding T lymphocyte recruitment in lung inflammation. Am J Respir Crit Care Med (2001) 1.32
Localization and kinetics of pyruvate-metabolizing enzymes in relation to aerobic alcoholic fermentation in Saccharomyces cerevisiae CBS 8066 and Candida utilis CBS 621. Biochim Biophys Acta (1989) 1.32
Mapping the fMet-tRNA(f)(Met) binding site of initiation factor IF2. EMBO J (2000) 1.30
Epithelial V-like antigen (EVA), a novel member of the immunoglobulin superfamily, expressed in embryonic epithelia with a potential role as homotypic adhesion molecule in thymus histogenesis. J Cell Biol (1998) 1.28
Protection against malaria morbidity: near-fixation of the alpha-thalassemia gene in a Nepalese population. Am J Hum Genet (1991) 1.28
Solution structure and backbone dynamics of the photoactive yellow protein. Biochemistry (1998) 1.27
The structure of the C4C4 ring finger of human NOT4 reveals features distinct from those of C3HC4 RING fingers. J Biol Chem (2000) 1.25
Structure of the fMet-tRNA(fMet)-binding domain of B. stearothermophilus initiation factor IF2. EMBO J (2000) 1.24
A homeobox gene, vax2, controls the patterning of the eye dorsoventral axis. Proc Natl Acad Sci U S A (1999) 1.24
Identification and characterization of a novel serine-threonine kinase gene from the Xp22 region. Genomics (1998) 1.23
Probing the nature of the blue-shifted intermediate of photoactive yellow protein in solution by NMR: hydrogen-deuterium exchange data and pH studies. Biochemistry (2000) 1.22
Conformational changes in the oligonucleotide duplex d(GCGTTGCG) x d(CGCAACGC) induced by formation of a cis-syn thymine dimer. A two-dimensional NMR study. Eur J Biochem (1987) 1.22
Triggering receptor expressed on myeloid cells: role in the diagnosis of lung infections. Eur Respir J (2004) 1.20
The solution structure of Lac repressor headpiece 62 complexed to a symmetrical lac operator. Structure (1999) 1.19
Solution structure of the HU protein from Bacillus stearothermophilus. J Mol Biol (1995) 1.18
Calcium channel blockers, postural vasoconstriction and dependent oedema in essential hypertension. J Hum Hypertens (2001) 1.17
Improved HSQC experiments for the observation of exchange broadened signals. J Biomol NMR (1996) 1.15
Solution structure of dimeric Mnt repressor (1-76). Biochemistry (1994) 1.14
The amino-terminal domain of LexA repressor is alpha-helical but differs from canonical helix-turn-helix proteins: a two-dimensional 1H NMR study. Proc Natl Acad Sci U S A (1989) 1.14
The structure in solution of the b domain of protein disulfide isomerase. J Biomol NMR (1999) 1.13
Characterization of Cxorf5 (71-7A), a novel human cDNA mapping to Xp22 and encoding a protein containing coiled-coil alpha-helical domains. Genomics (1998) 1.11
Protein structures from NMR. Biochemistry (1988) 1.11
Alteration of cardiac function in patients with temporal lobe epilepsy: different roles of EEG-ECG monitoring and spectral analysis of RR variability. Epilepsia (1997) 1.10
Strong DNA binding by covalently linked dimeric Lac headpiece: evidence for the crucial role of the hinge helices. Proc Natl Acad Sci U S A (2001) 1.09
Sensitivity enhancement in the TROSY experiment. J Magn Reson (1998) 1.09
Refined solution structure of the C-terminal DNA-binding domain of human immunovirus-1 integrase. Proteins (1999) 1.09
Barhl1, a gene belonging to a new subfamily of mammalian homeobox genes, is expressed in migrating neurons of the CNS. Hum Mol Genet (2000) 1.08
Dose-finding study and pharmacokinetics of epirubicin and paclitaxel over 3 hours: a regimen with high activity and low cardiotoxicity in advanced breast cancer. J Clin Oncol (1997) 1.07
The tetramerization domain of the Mnt repressor consists of two right-handed coiled coils. Nat Struct Biol (1999) 1.07
"Ensemble" iterative relaxation matrix approach: a new NMR refinement protocol applied to the solution structure of crambin. Proteins (1993) 1.07
Microalbuminuria, an integrated marker of cardiovascular risk in essential hypertension. J Hum Hypertens (2002) 1.06
Letter to the editor. J Cardiovasc Electrophysiol (2013) 1.06
LexA repressor and iron uptake regulator from Escherichia coli: new members of the CAP-like DNA binding domain superfamily. Protein Eng (1994) 1.05
Nuclear magnetic resonance solution structure of the Arc repressor using relaxation matrix calculations. J Mol Biol (1994) 1.05
Formation of the hinge helix in the lac repressor is induced upon binding to the lac operator. Nat Struct Biol (1996) 1.04
High-resolution structure of the phosphorylated form of the histidine-containing phosphocarrier protein HPr from Escherichia coli determined by restrained molecular dynamics from NMR-NOE data. J Mol Biol (1995) 1.04
Mutations in the glucocorticoid receptor DNA-binding domain mimic an allosteric effect of DNA. J Mol Biol (2000) 1.04
The revised structure of bottromycin A2. J Antibiot (Tokyo) (1983) 1.03
Hinge-helix formation and DNA bending in various lac repressor-operator complexes. EMBO J (1999) 1.03
A model for the LexA repressor DNA complex. Proteins (1995) 1.02
The peroxidation of thiocyanate catalysed by myeloperoxidase and lactoperoxidase. Biochim Biophys Acta (1982) 1.01
Solution structure and DNA-binding properties of the C-terminal domain of UvrC from E.coli. EMBO J (2002) 1.00
Structural alterations of alpha-crystallin during its chaperone action. Eur J Biochem (1998) 1.00
Two-step tumour targetting in ovarian cancer patients using biotinylated monoclonal antibodies and radioactive streptavidin. Eur J Nucl Med (1992) 1.00
Structure determination of a DNA octamer in solution by NMR spectroscopy. Effect of fast local motions. Biochemistry (1991) 0.98
H NMR study of a complex between the lac repressor headpiece and a 22 base pair symmetric lac operator. Biochemistry (1989) 0.98
Dinuclear alkyldiamine platinum antitumor compounds: a structure-activity relationship study. J Med Chem (2001) 0.98
Refined structure of lac repressor headpiece (1-56) determined by relaxation matrix calculations from 2D and 3D NOE data: change of tertiary structure upon binding to the lac operator. J Mol Biol (1996) 0.98
Non-diabetic microalbuminuria, endothelial dysfunction and cardiovascular disease. Vasc Med (2001) 0.97
Hydration dynamics of the collagen triple helix by NMR. J Mol Biol (2000) 0.97
Spatial arrangement of the three alpha helices in the solution conformation of E. coli lac repressor DNA-binding domain. FEBS Lett (1984) 0.97
Treatment of intracranial human glioblastoma by direct intratumoral administration of 131I-labelled anti-tenascin monoclonal antibody BC-2. Int J Cancer (1992) 0.97
Two-dimensional 1H NMR study of two cyclobutane type photodimers of thymidylyl-(3'----5')-thymidine. Eur Biophys J (1987) 0.97
A modified 'low pH' lignocaine method to isolate human monocytes: a comparison with other separation procedures. J Immunol Methods (1981) 0.96
A new test for the laboratory diagnosis of spherocytosis. Acta Haematol (1984) 0.96
Solution structure of the sequence-specific HMG box of the lymphocyte transcriptional activator Sox-4. J Biol Chem (1995) 0.95
Characterization of a doxorubicin-resistant murine melanoma line: studies on cross-resistance and its circumvention. Br J Cancer (1986) 0.95
Rationally designed strings of promiscuous CD4(+) T cell epitopes provide help to Haemophilus influenzae type b oligosaccharide: a model for new conjugate vaccines. Eur J Immunol (2001) 0.95
Hydrogen exchange studies of the Arc repressor: evidence for a monomeric folding intermediate. Biopolymers (1995) 0.95
Microalbuminuria and pulse pressure in hypertensive and atherosclerotic men. Hypertension (2000) 0.95
Identification of the ribosome binding sites of translation initiation factor IF3 by multidimensional heteronuclear NMR spectroscopy. RNA (1999) 0.94
PhoE signal peptide inserts into micelles as a dynamic helix-break-helix structure, which is modulated by the environment. A two-dimensional 1H NMR study. Biochemistry (1995) 0.94
The small heat-shock chaperone protein, alpha-crystallin, does not recognize stable molten globule states of cytosolic proteins. Biochim Biophys Acta (2000) 0.93
Observation of inter-subunit nuclear Overhauser effects in a dimeric protein. Application to the Arc repressor. FEBS Lett (1993) 0.93
EPR studies of the photodissociation reactions of cytochrome c oxidase-nitric oxide complexes. Biochim Biophys Acta (1982) 0.93
Predicting outcome after myocardial revascularization in patients with left ventricular dysfunction. Cardiovasc Surg (1998) 0.92