Published in Am J Pathol on May 01, 1997
TGF-β in progression of liver disease. Cell Tissue Res (2011) 2.22
Robustly detecting differential expression in RNA sequencing data using observation weights. Nucleic Acids Res (2014) 2.10
Inhibition of integrin alphavbeta6 on cholangiocytes blocks transforming growth factor-beta activation and retards biliary fibrosis progression. Gastroenterology (2008) 1.69
Liver fibrosis causes downregulation of miRNA-150 and miRNA-194 in hepatic stellate cells, and their overexpression causes decreased stellate cell activation. Am J Physiol Gastrointest Liver Physiol (2009) 1.63
Is liver fibrosis reversible? Gut (2000) 1.52
Dynamic changes of type I,III and IV collagen synthesis and distribution of collagen-producing cells in carbon tetrachloride-induced rat liver fibrosis. World J Gastroenterol (1999) 1.47
Altered balance between matrix metalloproteinases and their inhibitors in experimental biliary fibrosis. Am J Pathol (1998) 1.38
Proliferating bile duct epithelial cells are a major source of connective tissue growth factor in rat biliary fibrosis. Am J Pathol (2001) 1.32
Pentoxifylline downregulates profibrogenic cytokines and procollagen I expression in rat secondary biliary fibrosis. Gut (2002) 1.29
Inhibiting effect of antisense oligonucleotides phosphorthioate on gene expression of TIMP-1 in rat liver fibrosis. World J Gastroenterol (2001) 1.15
Dose dependent and divergent effects of superoxide anion on cell death, proliferation, and migration of activated human hepatic stellate cells. Gut (2005) 1.13
Antidiabetic thiazolidinediones inhibit invasiveness of pancreatic cancer cells via PPARgamma independent mechanisms. Gut (2004) 1.12
Oxidative and nitrosative stress and fibrogenic response. Clin Liver Dis (2008) 1.09
Matrix metalloproteinase-2 and tissue inhibitor of metalloproteinase-1 expression in fibrotic rat liver. World J Gastroenterol (2000) 1.05
Methodologic research on TIMP-1, TIMP-2 detection as a new diagnostic index for hepatic fibrosis and its significance. World J Gastroenterol (2002) 0.99
A role for thrombin in liver fibrosis. Gut (2004) 0.95
Fibrogenesis and fibrolysis in collagenous colitis. Patterns of procollagen types I and IV, matrix-metalloproteinase-1 and -13, and TIMP-1 gene expression. Am J Pathol (1999) 0.94
Endothelin receptor antagonist TAK-044 arrests and reverses the development of carbon tetrachloride induced cirrhosis in rats. Gut (2004) 0.90
Bioconjugation of oligonucleotides for treating liver fibrosis. Oligonucleotides (2007) 0.88
The performance of enhanced liver fibrosis (ELF) test for the staging of liver fibrosis: a meta-analysis. PLoS One (2014) 0.87
Stage-specific expression, immunolocalization of Clonorchis sinensis lysophospholipase and its potential role in hepatic fibrosis. Parasitol Res (2012) 0.85
Differential expression of matrix metalloproteinases and tissue inhibitors of metalloproteinases in thioacetamide-induced chronic liver injury. J Korean Med Sci (2010) 0.85
Effects of augmentation of liver regeneration recombinant plasmid on rat hepatic fibrosis. World J Gastroenterol (2005) 0.84
Effect of interleukin-10 and platelet-derived growth factor on expressions of matrix metalloproteinases-2 and tissue inhibitor of metalloproteinases-1 in rat fibrotic liver and cultured hepatic stellate cells. World J Gastroenterol (2004) 0.84
Collagen type XVIII/endostatin is differentially expressed in primary and metastatic colorectal cancers and ovarian carcinomas. Br J Cancer (2001) 0.83
Dietary copper triggers onset of fulminant hepatitis in the Long-Evans cinnamon rat model. World J Gastroenterol (2012) 0.83
Inhibitory effect of emodin on tissue inhibitor of metalloproteinases-1 (TIMP-1) expression in rat hepatic stellate cells. Dig Dis Sci (2006) 0.80
Rat model of fractionated (2 Gy/day) 60 Gy irradiation of the liver: long-term effects. Radiat Environ Biophys (2013) 0.80
Adiponectin reduces hepatic stellate cell migration by promoting tissue inhibitor of metalloproteinase-1 (TIMP-1) secretion. J Biol Chem (2015) 0.77
Expression of tissue inhibitors of metalloproteinases (TIMPs) in hepatocellular carcinoma. Korean J Intern Med (2000) 0.77
Anchoring hepatic gene expression with development of fibrosis and neoplasia in a toxicant-induced fish model of liver injury. Toxicol Pathol (2012) 0.76
Herbal compound 861 regulates mRNA expression of collagen synthesis- and degradation-related genes in human hepatic stellate cells. World J Gastroenterol (2008) 0.76
Tissue Inhibitor of Metalloproteinase-2 Suppresses Collagen Synthesis in Cultured Keloid Fibroblasts. Plast Reconstr Surg Glob Open (2015) 0.75
Curcumin targets multiple pathways to halt hepatic stellate cell activation: updated mechanisms in vitro and in vivo. Dig Dis Sci (2014) 0.75
Rutin Attenuates Hepatotoxicity in High-Cholesterol-Diet-Fed Rats. Oxid Med Cell Longev (2016) 0.75
Is the neutrophil to lymphocyte ratio associated with liver fibrosis in patients with chronic hepatitis B? World J Gastroenterol (2015) 0.75
Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal Biochem (1987) 281.19
Various rat adult tissues express only one major mRNA species from the glyceraldehyde-3-phosphate-dehydrogenase multigenic family. Nucleic Acids Res (1985) 10.76
A matrix metalloproteinase expressed on the surface of invasive tumour cells. Nature (1994) 9.31
Matrix metalloproteinases and their inhibitors in connective tissue remodeling. FASEB J (1991) 8.29
Sequence of human tissue inhibitor of metalloproteinases and its identity to erythroid-potentiating activity. Nature (1985) 3.97
Proteolytic remodeling of extracellular matrix. Curr Opin Cell Biol (1995) 3.39
In situ hybridization for procollagen types I, III and IV mRNA in normal and fibrotic rat liver: evidence for predominant expression in nonparenchymal liver cells. Hepatology (1989) 2.34
Tissue cooperation in a proteolytic cascade activating human interstitial collagenase. Proc Natl Acad Sci U S A (1989) 2.26
Metalloproteinases mediate extracellular matrix degradation by cells from mouse blastocyst outgrowths. Development (1992) 2.19
Stromal expression of 72 kda type IV collagenase (MMP-2) and TIMP-2 mRNAs in colorectal neoplasia. Am J Pathol (1992) 2.17
Tissue inhibitor of metalloproteinases-2 (TIMP-2) mRNA expression in tumor cell lines and human tumor tissues. J Biol Chem (1990) 1.98
Lipocytes from normal rat liver release a neutral metalloproteinase that degrades basement membrane (type IV) collagen. J Clin Invest (1989) 1.95
The synthesis of proteoglycans in fat-storing cells of rat liver. Hepatology (1987) 1.84
Expression of tissue inhibitor of metalloproteinases 1 and 2 is increased in fibrotic human liver. Gastroenterology (1996) 1.79
Procollagen expression by nonparenchymal rat liver cells in experimental biliary fibrosis. Gastroenterology (1990) 1.77
Structure of the human type IV collagenase gene. J Biol Chem (1990) 1.68
Expression of platelet-derived growth factor and its receptors in normal human liver and during active hepatic fibrogenesis. Am J Pathol (1996) 1.68
Differential expression of matrix-metalloproteinase-1 and -2 genes in normal and fibrotic human liver. Am J Pathol (1994) 1.64
Human hepatic lipocytes synthesize tissue inhibitor of metalloproteinases-1. Implications for regulation of matrix degradation in liver. J Clin Invest (1992) 1.62
Interleukin-6 induces the synthesis of tissue inhibitor of metalloproteinases-1/erythroid potentiating activity (TIMP-1/EPA). J Biol Chem (1991) 1.58
Transforming growth factors beta 1 and beta 2 are differentially expressed in fibrotic liver disease. Am J Pathol (1991) 1.55
The stellate cell (Ito-cell, fat-storing cell, lipocyte, perisinusoidal cell) of the liver. New insights into pathophysiology of an intriguing cell. Virchows Arch B Cell Pathol Incl Mol Pathol (1991) 1.49
Distinct localization of collagenase and tissue inhibitor of metalloproteinases expression in wound healing associated with ulcerative pyogenic granuloma. J Clin Invest (1992) 1.45
Increase in type I and type III collagens in human alcoholic liver cirrhosis. Proc Natl Acad Sci U S A (1976) 1.41
Regulation of the autoactivation of human 72-kDa progelatinase by tissue inhibitor of metalloproteinases-2. J Biol Chem (1991) 1.40
Regulation of the expression of tissue inhibitor of metalloproteinases and collagenase by retinoids and glucocorticoids in human fibroblasts. J Clin Invest (1987) 1.35
Regulation of extracellular matrix synthesis by transforming growth factor beta 1 in human fat-storing cells. Gastroenterology (1993) 1.35
Stromelysin and tissue inhibitor of metalloproteinases gene expression in rheumatoid arthritis synovium. Am J Pathol (1992) 1.34
Distribution of collagenase and tissue inhibitor of metalloproteinases (TIMP) in colorectal tumours. Int J Cancer (1991) 1.34
Structure and expression in breast tumors of human TIMP-3, a new member of the metalloproteinase inhibitor family. Cancer Res (1994) 1.30
Cellular sources of noncollagenous matrix proteins: role of fat-storing cells in fibrogenesis. Semin Liver Dis (1990) 1.28
Increased expression of matrix metalloproteinase-II in experimental liver fibrosis in rats. Hepatology (1995) 1.26
Transforming growth factor-beta 1 and type I procollagen transcripts during regeneration and early fibrosis of rat liver. Lab Invest (1990) 1.22
Preferential inhibition of 72- and 92-kDa gelatinases by tissue inhibitor of metalloproteinases-2. J Biol Chem (1991) 1.18
Temporal and spatial patterns of transin/stromelysin RNA expression following toxic injury in rat liver. Virchows Arch B Cell Pathol Incl Mol Pathol (1991) 1.14
Human progelatinase A can be activated by matrilysin. FEBS Lett (1994) 1.10
The complex between a tissue inhibitor of metalloproteinases (TIMP-2) and 72-kDa progelatinase is a metalloproteinase inhibitor. Eur J Biochem (1991) 1.08
Identification of a serum- and phorbol ester-responsive element in the murine tissue inhibitor of metalloproteinase gene. J Biol Chem (1991) 1.06
Matrix degradation in the liver. Semin Liver Dis (1990) 1.05
Kupffer cell-derived 95-kd type IV collagenase/gelatinase B: characterization and expression in cultured cells. Hepatology (1995) 1.03
Temporal and spatial patterns of proto-oncogene expression at early stages of toxic liver injury in the rat. Lab Invest (1991) 0.93
TIMP-1 protein expression is stimulated by IL-1 beta and IL-6 in primary rat hepatocytes. FEBS Lett (1994) 0.92
Synthesis of tissue inhibitor of metalloproteinase-1 (TIMP-1) in human hepatoma cells (HepG2). Up-regulation by interleukin-6 and transforming growth factor beta 1. FEBS Lett (1992) 0.86
Large inhibitor of metalloproteinases (LIMP) contains tissue inhibitor of metalloproteinases (TIMP)-2 bound to 72,000-M(r) progelatinase. Biochem J (1992) 0.86
Basal expression of the gene (TIMP) encoding the murine tissue inhibitor of metalloproteinases is mediated through AP1- and CCAAT-binding factors. Gene (1992) 0.85
Expression of TIMP in fetal and adult mouse tissues studied by in situ hybridization. Matrix Suppl (1992) 0.78
Identification of tissue transglutaminase as the autoantigen of celiac disease. Nat Med (1997) 7.42
Vascular invasion and histopathologic grading determine outcome after liver transplantation for hepatocellular carcinoma in cirrhosis. Hepatology (2001) 3.26
Italian cross-sectional growth charts for height, weight and BMI (2 to 20 yr). J Endocrinol Invest (2006) 3.17
Retracted Long-term results and risk factors influencing outcome of major bile duct injuries following cholecystectomy. Br J Surg (2005) 3.06
Extensive genetic polymorphism in the human CYP2B6 gene with impact on expression and function in human liver. Pharmacogenetics (2001) 3.05
Extended resections for hilar cholangiocarcinoma. Ann Surg (1999) 2.93
The role of liver transplantation in hepatobiliary malignancy. A retrospective analysis of 95 patients with particular regard to tumor stage and recurrence. Ann Surg (1989) 2.71
Autoantibodies to tissue transglutaminase as predictors of celiac disease. Gastroenterology (1998) 2.68
The phosphorylation of liver ribosomal proteins in vivo. Evidence that only a single small subunit protein (S6) is phosphorylated. J Biol Chem (1974) 2.40
In situ hybridization for procollagen types I, III and IV mRNA in normal and fibrotic rat liver: evidence for predominant expression in nonparenchymal liver cells. Hepatology (1989) 2.34
Sexual segregation in ungulates: a comparative test of three hypotheses. Biol Rev Camb Philos Soc (2002) 2.34
Neurofibromatosis type 1 growth charts. Am J Med Genet (1999) 2.32
The hedgehog pathway regulates remodelling responses to biliary obstruction in rats. Gut (2008) 2.26
A randomized, controlled study to assess the conversion from calcineurin-inhibitors to everolimus after liver transplantation--PROTECT. Am J Transplant (2012) 2.24
The genetic determinants of the CYP3A5 polymorphism. Pharmacogenetics (2001) 2.21
The impact of carbon dioxide pneumoperitoneum on liver regeneration after liver resection in a rat model. Surg Endosc (2009) 2.16
Maternal triglyceride levels and newborn weight in pregnant women with normal glucose tolerance. Diabet Med (2005) 2.10
Herbal medicine in the treatment of liver diseases. Dig Liver Dis (2007) 2.02
Chloracne due to o-dichlorobenzene in a laboratory worker. Contact Dermatitis (2005) 2.02
[Results of a S2k-Consensus Conference of the German Society of Gastroenterolgy, Digestive- and Metabolic Diseases (DGVS) in conjunction with the German Coeliac Society (DZG) regarding coeliac disease, wheat allergy and wheat sensitivity]. Z Gastroenterol (2014) 2.02
Increased expression of monocyte chemotactic protein-1 during active hepatic fibrogenesis: correlation with monocyte infiltration. Am J Pathol (1998) 2.01
P-selectin induces the expression of tissue factor on monocytes. Proc Natl Acad Sci U S A (1994) 2.00
Normalised intrinsic mortality risk in liver transplantation: European Liver Transplant Registry study. Lancet (2000) 1.99
Hepatitis B virus with antigenically altered hepatitis B surface antigen is selected by high-dose hepatitis B immune globulin after liver transplantation. Hepatology (1998) 1.98
Practical implications of coexistent different technologies in clinical chemical laboratories. Solid phase chemistry and conventional analysis. Eur J Clin Chem Clin Biochem (1991) 1.96
Successful prevention of hepatitis C virus (HCV) liver graft reinfection by silibinin mono-therapy. J Hepatol (2010) 1.95
Thyroid function differently affects serum cystatin C and creatinine concentrations. J Endocrinol Invest (2005) 1.86
Delayed introduction of reduced-dose tacrolimus, and renal function in liver transplantation: the 'ReSpECT' study. Am J Transplant (2008) 1.86
Liver tumors: comparison of MR imaging with Gd-EOB-DTPA and Gd-DTPA. Radiology (1996) 1.86
Modulation of transforming growth factor beta response and signaling during transdifferentiation of rat hepatic stellate cells to myofibroblasts. Hepatology (2000) 1.84
The synthesis of proteoglycans in fat-storing cells of rat liver. Hepatology (1987) 1.84
Management and outcome of patients with combined bile duct and hepatic arterial injuries after laparoscopic cholecystectomy. Surgery (2004) 1.82
Differential expression of collagen types I, III, and IV by fat-storing (Ito) cells in vitro. Gastroenterology (1992) 1.78
Procollagen expression by nonparenchymal rat liver cells in experimental biliary fibrosis. Gastroenterology (1990) 1.77
Treatment of "stable" vitiligo by Timedsurgery and transplantation of cultured epidermal autografts. Arch Dermatol (2000) 1.74
Methylprednisolone therapy in deceased donors reduces inflammation in the donor liver and improves outcome after liver transplantation: a prospective randomized controlled trial. Ann Surg (2008) 1.74
Fat-storing cells as liver-specific pericytes. Spatial dynamics of agonist-stimulated intracellular calcium transients. J Clin Invest (1992) 1.71
Expression of platelet-derived growth factor and its receptors in normal human liver and during active hepatic fibrogenesis. Am J Pathol (1996) 1.68
Alemtuzumab (Campath-1H) and tacrolimus monotherapy after renal transplantation: results of a prospective randomized trial. Am J Transplant (2008) 1.67
Neonatal anthropometric charts: what they are, what they are not. Arch Dis Child Fetal Neonatal Ed (2007) 1.66
Endothelin 1 is overexpressed in human cirrhotic liver and exerts multiple effects on activated hepatic stellate cells. Gastroenterology (1996) 1.66
Differential expression of matrix-metalloproteinase-1 and -2 genes in normal and fibrotic human liver. Am J Pathol (1994) 1.64
Silymarin retards collagen accumulation in early and advanced biliary fibrosis secondary to complete bile duct obliteration in rats. Hepatology (1997) 1.64
C4d in acute rejection after liver transplantation--a valuable tool in differential diagnosis to hepatitis C recurrence. Am J Transplant (2006) 1.62
Activation of rat liver perisinusoidal lipocytes by transforming growth factors derived from myofibroblastlike cells. A potential mechanism of self perpetuation in liver fibrogenesis. J Clin Invest (1992) 1.62
An oral endothelin-A receptor antagonist blocks collagen synthesis and deposition in advanced rat liver fibrosis. Gastroenterology (2000) 1.60
The integrated value of serum procollagen III peptide over time predicts hepatic hydroxyproline content and stainable collagen in a model of dietary cirrhosis in the rat. Hepatology (1989) 1.60
Autologous fibrin-cultured limbal stem cells permanently restore the corneal surface of patients with total limbal stem cell deficiency. Transplantation (2001) 1.60
Hepatocellular carcinoma in association with hepatic focal nodular hyperplasia. Acta Radiol (2006) 1.59
Prolonged n-3 polyunsaturated fatty acid supplementation ameliorates hepatic steatosis in patients with non-alcoholic fatty liver disease: a pilot study. Aliment Pharmacol Ther (2006) 1.58
Transforming growth factors beta 1 and beta 2 are differentially expressed in fibrotic liver disease. Am J Pathol (1991) 1.55
Production and characterisation of a monoclonal antibody to a cell-surface, glucomannoprotein constituent of Candida albicans and other pathogenic Candida species. J Med Microbiol (1988) 1.54
[S3-Guidelines "Exocrine pancreatic cancer" 2007]. Z Gastroenterol (2007) 1.52
Hepatocellular carcinoma: evaluation with dynamic and static gadobenate dimeglumine-enhanced MR imaging and histopathologic correlation. Radiology (1997) 1.52
Enhanced release of cytokines, interleukin-2 receptors, and neopterin after long-distance running. Clin Immunol Immunopathol (1992) 1.51
Radical resection and liver grafting as the two main components of surgical strategy in the treatment of proximal bile duct cancer. World J Surg (1988) 1.51
Differentiation between benign and malignant adrenal mass using contrast-enhanced ultrasound. Ultraschall Med (2011) 1.50
Big endothelin-1 and endothelin-1 plasma levels are correlated with the severity of primary pulmonary hypertension. Chest (2001) 1.49
Initially unresectable hilar cholangiocarcinoma: hepatic regeneration after transarterial embolization. Radiology (1998) 1.49
Transarterial chemoembolization for hepatocellular carcinoma: volumetric and morphologic CT criteria for assessment of prognosis and therapeutic success-results from a liver transplantation center. Radiology (2000) 1.48
Liver graft-transmitted glioblastoma multiforme. A case report and experience with 13 multiorgan donors suffering from primary cerebral neoplasia. Transpl Int (1996) 1.47
The laparoscopic Janeway gastrostomy. An alternative technique when percutaneous endoscopic gastrostomy is impractical. Endoscopy (2001) 1.46
Magnetic resonance imaging including magnetic resonance cholangiopancreatography for tumor localization and therapy planning in malignant hilar obstructions. Acta Radiol (2005) 1.46
Management and outcomes of haemorrhage after pancreatogastrostomy versus pancreatojejunostomy. Br J Surg (2011) 1.46
Italian cross-sectional growth charts for height, weight and BMI (6-20 y). Eur J Clin Nutr (2002) 1.46
Improved survival in liver transplant recipients receiving prolonged-release tacrolimus in the European Liver Transplant Registry. Am J Transplant (2015) 1.46
Experiences with liver transplantation in Hannover. Hepatology (1984) 1.45
Bone loss in response to long-term glucocorticoid therapy. Bone Miner (1990) 1.44
Reliability of transient elastography for the diagnosis of advanced fibrosis in chronic hepatitis C. Gut (2008) 1.43
Venous complications after orthotopic liver transplantation. Clin Transplant (2000) 1.43
A histone deacetylase inhibitor, trichostatin A, suppresses myofibroblastic differentiation of rat hepatic stellate cells in primary culture. Hepatology (1999) 1.40
Do Behçet's syndrome patients with acne and arthritis comprise a true subset? Comment on the article by Hatemi et al. Arthritis Rheum (2009) 1.40
Liver transplantation after organ preservation with normothermic extracorporeal perfusion. Ann Surg (2001) 1.40
Diagnosis of enteroceles by dynamic anorectal endosonography. Dis Colon Rectum (2000) 1.40
[Simulation of a colon carcinoma: diuretic-induced ulcerative-stricturing ischemic colitis]. Dtsch Med Wochenschr (2004) 1.39
Deflazacort versus methylprednisolone in polymyalgia rheumatica: clinical equivalence and relative antiinflammatory potency of different treatment regimens. J Rheumatol (1995) 1.39
[The clinical value of laminin determination in advanced liver cirrhosis]. Dtsch Med Wochenschr (1996) 1.39
Donor criteria in hepatic transplantation. Langenbecks Arch Chir (1994) 1.38
[Mesenteric artery occlusion as a rare complication of thromboangiitis obliterans]. Chirurg (2002) 1.38
[Indications for liver biopsy in liver tumors]. Dtsch Med Wochenschr (2000) 1.38
Prospective randomized trial to assess the value of preemptive oral therapy for CMV infection following liver transplantation. Transplantation (2001) 1.38
High expression of RelA/p65 is associated with activation of nuclear factor-kappaB-dependent signaling in pancreatic cancer and marks a patient population with poor prognosis. Br J Cancer (2007) 1.37
Unilateral posterior crossbite is not associated with TMJ clicking in young adolescents. J Dent Res (2007) 1.37
Characterization of integrin receptors in normal and neoplastic human brain. Am J Pathol (1993) 1.37
Clinical extracorporeal hybrid liver support--phase I study with primary porcine liver cells. Xenotransplantation (2003) 1.35
Immunological measurement of transforming growth factor-beta 1 (TGF-beta1) in blood; assay development and comparison. Clin Chem (1997) 1.35
Regulation of extracellular matrix synthesis by transforming growth factor beta 1 in human fat-storing cells. Gastroenterology (1993) 1.35
Proliferating bile duct epithelial cells are a major source of connective tissue growth factor in rat biliary fibrosis. Am J Pathol (2001) 1.32