PubRank

L F Povirk

Author PubWeight™ 47.76‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 3'-phosphodiesterase activity of human apurinic/apyrimidinic endonuclease at DNA double-strand break ends. Nucleic Acids Res 1997 1.72
2 DNA double-strand breaks and alkali-labile bonds produced by bleomycin. Nucleic Acids Res 1977 1.68
3 Endonuclease-resistant apyrimidinic sites formed by neocarzinostatin at cytosine residues in DNA: evidence for a possible role in mutagenesis. Proc Natl Acad Sci U S A 1985 1.66
4 Accurate in vitro end joining of a DNA double strand break with partially cohesive 3'-overhangs and 3'-phosphoglycolate termini: effect of Ku on repair fidelity. J Biol Chem 2001 1.57
5 Induction of apoptotic DNA fragmentation and cell death in HL-60 human promyelocytic leukemia cells by pharmacological inhibitors of protein kinase C. Cancer Res 1994 1.41
6 Bleomycin-induced DNA lesions at mutational hot spots: implications for the mechanism of double-strand cleavage. Proc Natl Acad Sci U S A 1990 1.37
7 The effect of 313 nanometer light on initiation of replicons in mammalian cell DNA containing bromodeoxyuridine. Biochim Biophys Acta 1976 1.37
8 Neocarzinostatin chromophore binds to deoxyribonucleic acid by intercalation. Biochemistry 1981 1.17
9 Binding of bleomycin to DNA: intercalation of the bithiazole rings. Biochemistry 1979 1.15
10 p53-Dependent accelerated senescence induced by ionizing radiation in breast tumour cells. Int J Radiat Biol 2005 1.10
11 Localization of inhibition of replicon initiation to damaged regions of DNA. J Mol Biol 1977 1.08
12 Small deletion and insertion mutations induced by the topoisomerase II inhibitor teniposide in CHO cells and comparison with sites of drug-stimulated DNA cleavage in vitro. J Mol Biol 1993 1.03
13 Spontaneous cleavage of bleomycin-induced abasic sites in chromatin and their mutagenicity in mammalian shuttle vectors. Biochemistry 1993 1.03
14 Covalent adducts of DNA and the nonprotein chromophore of neocarzinostatin contain a modified deoxyribose. Proc Natl Acad Sci U S A 1982 1.02
15 Construction of a vector containing a site-specific DNA double-strand break with 3'-phosphoglycolate termini and analysis of the products of end-joining in CV-1 cells. Int J Radiat Biol 1996 1.01
16 Competition between anaerobic covalent linkage of neocarzinostatin chromophore to deoxyribose in DNA and oxygen-dependent strand breakage and base release. Biochemistry 1984 0.99
17 Binding of the nonprotein chromophore of neocarzinostatin to deoxyribonucleic acid. Biochemistry 1980 0.98
18 End-joining of free radical-mediated DNA double-strand breaks in vitro is blocked by the kinase inhibitor wortmannin at a step preceding removal of damaged 3' termini. J Biol Chem 1996 0.96
19 Rate of DNA chain elongation in ultraviolet light-irradiated mammalian cells as estimated by a bromodeoxyuridine photolysis method. Biophys J 1976 0.95
20 Base substitution mutations induced in the cI gene of lambda phage by neocarzinostatin chromophore: correlation with depyrimidination hotspots at the sequence AGC. Nucleic Acids Res 1986 0.94
21 Effect of in vitro cleavage of apurinic/apyrimidinic sites on bleomycin-induced mutagenesis of repackaged lambda phage. Mutat Res 1990 0.93
22 Copper(II).bleomycin, iron(III).bleomycin, and copper(II).phleomycin: comparative study of deoxyribonucleic acid binding. Biochemistry 1981 0.93
23 A precise interchromosomal reciprocal exchange between hot spots for cleavable complex formation by topoisomerase II in amsacrine-treated Chinese hamster ovary cells. Cancer Res 1997 0.93
24 Catalytic release of deoxyribonucleic acid bases by oxidation and reduction of an iron.bleomycin complex. Biochemistry 1979 0.92
25 Highly conservative reciprocal translocations formed by apparent joining of exchanged DNA double-strand break ends. Proc Natl Acad Sci U S A 1997 0.92
26 Action of bleomycin on structural mimics of intermediates in DNA double-strand cleavage. Chem Res Toxicol 1998 0.91
27 Bleomycin-induced mutagenesis in repackaged lambda phage: base substitution hotspots at the sequence C-G-C-C. Mutat Res 1987 0.89
28 Specificity and kinetics of interstrand and intrastrand bifunctional alkylation by nitrogen mustards at a G-G-C sequence. Nucleic Acids Res 1997 0.88
29 Homogeneous preparations of 3'-phosphoglycolate-terminated oligodeoxynucleotides from bleomycin-treated DNA as verified by electrospray ionization Fourier transform ion cyclotron resonance mass spectrometry. Anal Biochem 2001 0.87
30 Specificity of DNA base release by bleomycin. Biochim Biophys Acta 1978 0.86
31 Implication of DNA-dependent protein kinase in an early, essential, local phosphorylation event during end-joining of DNA double-strand breaks in vitro. Biochemistry 1998 0.86
32 Stoichiometric uptake of molecular oxygen and consumption of sulfhydryl groups by neocarzinostatin chromophore bound to DNA. J Biol Chem 1983 0.86
33 Detection of neocarzinostatin chromophore-deoxyribose adducts as exonuclease-resistant sites in defined-sequence DNA. Biochemistry 1985 0.85
34 Interaction of DNA-dependent protein kinase and poly(ADP-ribose) polymerase with radiation-induced DNA strand breaks. Radiat Res 1997 0.85
35 Molecular mechanism of novel DNA sugar damage by an antitumour protein antibiotic. Drugs Exp Clin Res 1986 0.85
36 Neocarzinostatin chromophore-DNA adducts: evidence for a covalent linkage to the oxidized C-5' of deoxyribose. Nucleic Acids Res 1982 0.85
37 Effects of bryostatin 1 and other pharmacological activators of protein kinase C on 1-[beta-D-arabinofuranosyl]cytosine-induced apoptosis in HL-60 human promyelocytic leukemia cells. Biochem Pharmacol 1994 0.84
38 Thermolabile adenine adducts and A.T base pair substitutions induced by nitrogen mustard analogues in an SV40-based shuttle plasmid. Biochemistry 1991 0.83
39 Melphalan-induced mutagenesis in an SV40-based shuttle vector: predominance of A.T----T.A transversions. Cancer Res 1990 0.83
40 DNA damage induced by bleomycin, neocarzinostatin, and melphalan in a precisely positioned nucleosome. Asymmetry in protection at the periphery of nucleosome-bound DNA. J Biol Chem 1994 0.81
41 DNA sequence analysis of mutations induced by melphalan in the CHO aprt locus. Cancer Genet Cytogenet 1992 0.80
42 Targeted base substitutions and small deletions induced by neocarzinostatin at the APRT locus in plateau-phase CHO cells. Mutat Res 1997 0.80
43 Inhibition of mammalian deoxyribonucleic acid synthesis by neocarzinostatin: selective effect on replicon initiation in CHO cells and resistant synthesis in ataxia telangiectasia fibroblasts. Biochemistry 1982 0.79
44 Effect of distamycin on chlorambucil-induced mutagenesis in pZ189: evidence of a role for minor groove alkylation at adenine N-3. Mutagenesis 1994 0.78
45 Influence of amsacrine (m-AMSA) on bulk and gene-specific DNA damage and c-myc expression in MCF-7 breast tumor cells. Biochem Pharmacol 1994 0.77
46 Dissociation between bulk damage to DNA and the antiproliferative activity of teniposide (VM-26) in the MCF-7 breast tumor cell line: evidence for induction of gene-specific damage and alterations in gene expression. Cancer Res 1993 0.76
47 Ionizing radiation-induced DNA strand breakage and rejoining in specific genomic regions as determined by an alkaline unwinding/Southern blotting method. Int J Radiat Biol 1995 0.75
48 Deletion/insertion mutation that causes biotinidase deficiency may result from the formation of a quasipalindromic structure. Hum Mol Genet 1996 0.75
49 Expression of protein-associated DNA damage in the alkaline elution assay in the absence of enzymatic deproteinization. Cancer Commun 1989 0.75
50 A combined alkaline unwinding/Southern blotting assay for measuring low levels of cellular DNA breakage within specific genomic regions. Oncol Res 1992 0.75
51 Inhibition of protein kinase C activator-mediated induction of p21CIP1 and p27KIP1 by deoxycytidine analogs in human leukemia cells: relationship to apoptosis and differentiation. Biochem Pharmacol 1999 0.75
52 Enhanced amsacrine-induced mutagenesis in plateau-phase Chinese hamster ovary cells, with targeting of +1 frameshifts to free 3' ends of topoisomerase II cleavable complexes. Cancer Res 1999 0.75
53 Monofunctional adenine N-3 adducts of melphalan: occurrence at a mutational hotspot sequence and resistance to removal by AlkA protein. Environ Mol Mutagen 1998 0.75
54 Mapping of the cleavage-associated bleomycin binding site on DNA with a new method based on site-specific blockage of the minor groove with N2-isobutyrylguanine. Biochemistry 1997 0.75
55 Selective damage to the active X chromosome by camptothecin and amsacrine as determined by an allele-specific alkaline unwinding assay. Biochem Pharmacol 1995 0.75