Clonal genetic alterations in the lungs of current and former smokers.

PubWeight™: 3.03‹?› | Rank: Top 1%

🔗 View Article (PMID 9196251)

Published in J Natl Cancer Inst on June 18, 1997

Authors

L Mao1, J S Lee, J M Kurie, Y H Fan, S M Lippman, J J Lee, J Y Ro, A Broxson, R Yu, R C Morice, B L Kemp, F R Khuri, G L Walsh, W N Hittelman, W K Hong

Author Affiliations

1: Department of Thoracic/Head and Neck Medical Oncology, The University of Texas M.D. Anderson Cancer Center, Houston 77030, USA.

Articles citing this

Aberrant methylation of p16(INK4a) is an early event in lung cancer and a potential biomarker for early diagnosis. Proc Natl Acad Sci U S A (1998) 3.80

Evolution of neoplastic cell lineages in Barrett oesophagus. Nat Genet (1999) 3.30

Molecular damage in the bronchial epithelium of current and former smokers. J Natl Cancer Inst (1997) 2.83

EMT and stem cell-like properties associated with miR-205 and miR-200 epigenetic silencing are early manifestations during carcinogen-induced transformation of human lung epithelial cells. Cancer Res (2011) 2.32

Widely dispersed p53 mutation in respiratory epithelium. A novel mechanism for field carcinogenesis. J Clin Invest (1997) 2.30

Reversible and permanent effects of tobacco smoke exposure on airway epithelial gene expression. Genome Biol (2007) 2.20

A comprehensive survey of clonal diversity measures in Barrett's esophagus as biomarkers of progression to esophageal adenocarcinoma. Cancer Prev Res (Phila) (2010) 1.89

The field of tissue injury in the lung and airway. Cancer Prev Res (Phila) (2008) 1.77

Genetic, biochemical, and crystallographic characterization of Fhit-substrate complexes as the active signaling form of Fhit. Proc Natl Acad Sci U S A (1998) 1.68

Chromosomal imbalances in Barrett's adenocarcinoma and the metaplasia-dysplasia-carcinoma sequence. Am J Pathol (2000) 1.57

Randomized, double-blind, placebo-controlled, phase III chemoprevention trial of selenium supplementation in patients with resected stage I non-small-cell lung cancer: ECOG 5597. J Clin Oncol (2013) 1.54

Pathogenesis of lung cancer: 100 year report. Am J Respir Cell Mol Biol (2005) 1.44

Oral epithelium as a surrogate tissue for assessing smoking-induced molecular alterations in the lungs. Cancer Prev Res (Phila) (2008) 1.32

Smoking and lung cancer: the role of inflammation. Proc Am Thorac Soc (2008) 1.31

Lung cancer. 9: Molecular biology of lung cancer: clinical implications. Thorax (2003) 1.28

Molecular analysis of microdissected tumors and preneoplastic intraductal lesions in pancreatic carcinoma. Am J Pathol (2000) 1.28

Deregulated EGFR signaling during lung cancer progression: mutations, amplicons, and autocrine loops. Cancer Prev Res (Phila) (2008) 1.25

Sequence of the FRA3B common fragile region: implications for the mechanism of FHIT deletion. Proc Natl Acad Sci U S A (1997) 1.24

Fhit interaction with ferredoxin reductase triggers generation of reactive oxygen species and apoptosis of cancer cells. J Biol Chem (2008) 1.22

Fhit tumor suppressor: guardian of the preneoplastic genome. Future Oncol (2008) 1.21

Declining cellular fitness with age promotes cancer initiation by selecting for adaptive oncogenic mutations. Biochim Biophys Acta (2007) 1.21

Elevated epithelial insulin-like growth factor expression is a risk factor for lung cancer development. Cancer Res (2009) 1.15

Molecular changes in the bronchial epithelium of patients with small cell lung cancer. Clin Cancer Res (2000) 1.14

Impact of smoking status on the biological behavior of lung cancer. Surg Today (2007) 1.14

Impact of smoking cessation on global gene expression in the bronchial epithelium of chronic smokers. Cancer Prev Res (Phila) (2008) 1.13

The oral cavity as a molecular mirror of lung carcinogenesis. Cancer Prev Res (Phila) (2008) 1.12

Pulmonary adenocarcinoma: a renewed entity in 2011. Respirology (2012) 1.09

Genetic heterogeneity in saliva from patients with oral squamous carcinomas: implications in molecular diagnosis and screening. J Mol Diagn (2001) 1.07

Evolving concepts in lung carcinogenesis. Semin Respir Crit Care Med (2011) 1.03

The BATTLE to personalize lung cancer prevention through reverse migration. Cancer Prev Res (Phila) (2011) 1.02

Preneoplastic lesions of the lung. Respir Res (2002) 1.01

The FHIT gene product: tumor suppressor and genome "caretaker". Cell Mol Life Sci (2014) 1.01

Laser capture microdissection in the genomic and proteomic era: targeting the genetic basis of cancer. Int J Clin Exp Pathol (2008) 1.00

Genomic impact of cigarette smoke, with application to three smoking-related diseases. Crit Rev Toxicol (2012) 1.00

Early glandular neoplasia of the lung. Respir Res (2000) 0.98

The molecular basis of lung cancer: molecular abnormalities and therapeutic implications. Respir Res (2003) 0.97

Following mitochondrial footprints through a long mucosal path to lung cancer. PLoS One (2009) 0.97

Airway gene expression in chronic obstructive pulmonary disease. Proc Am Thorac Soc (2009) 0.95

Lung cancer . 3: Fluorescence bronchoscopy: clinical dilemmas and research opportunities. Thorax (2003) 0.95

Characterizing the molecular spatial and temporal field of injury in early-stage smoker non-small cell lung cancer patients after definitive surgery by expression profiling. Cancer Prev Res (Phila) (2012) 0.92

Survivin expression in normal human bronchial epithelial cells: an early and critical step in tumorigenesis induced by tobacco exposure. Carcinogenesis (2008) 0.87

Enriching the molecular definition of the airway "field of cancerization:" establishing new paradigms for the patient at risk for lung cancer. Cancer Prev Res (Phila) (2012) 0.84

Passenger mutations as a marker of clonal cell lineages in emerging neoplasia. Semin Cancer Biol (2010) 0.83

Preclinical Murine Models for Lung Cancer: Clinical Trial Applications. Biomed Res Int (2015) 0.83

Microsatellite mutations in buccal cells are associated with aging and head and neck carcinoma. Br J Cancer (2008) 0.82

Smoking, COPD, and 3-nitrotyrosine levels of plasma proteins. Environ Health Perspect (2011) 0.82

Personalizing lung cancer prevention through a reverse migration strategy. Top Curr Chem (2013) 0.82

Combined MET inhibition and topoisomerase I inhibition block cell growth of small cell lung cancer. Mol Cancer Ther (2013) 0.81

Allelic imbalance in 1p, 7q, 9p, 11p, 12q and 16q regions in non-small cell lung carcinoma and its clinical association: a pilot study. Mol Biol Rep (2013) 0.80

Significant frequency of allelic imbalance in 3p region covering RARβ and MLH1 loci seems to be essential in molecular non-small cell lung cancer diagnosis. Med Oncol (2013) 0.79

Detection of codon 12 K-ras mutations in non-neoplastic mucosa from bronchial carina in patients with lung adenocarcinomas. Br J Cancer (2000) 0.79

Topographical distributions of allelic loss in individual non-small-cell lung cancers. Am J Pathol (2000) 0.79

Updates and controversies in the rapidly evolving field of lung cancer screening, early detection, and chemoprevention. Cancers (Basel) (2014) 0.79

Mammalian nitrilase 1 homologue Nit1 is a negative regulator in T cells. Int Immunol (2009) 0.78

Update on biomarkers for the detection of lung cancer. Lung Cancer (Auckl) (2012) 0.77

The smoking gun and the damage done: genetic alterations in the lungs of smokers. J Natl Cancer Inst (1997) 0.77

PPARγ in head and neck cancer prevention. Oral Oncol (2014) 0.77

Frequent expression of MAGE1 tumor antigens in bronchial epithelium of smokers without lung cancer. Exp Ther Med (2010) 0.76

Genetics and pulmonary medicine. 7. Somatic mutations in the development of lung cancer. Thorax (1998) 0.76

Can Peto's paradox be used as the null hypothesis to identify the role of evolution in natural resistance to cancer? A critical review. BMC Cancer (2015) 0.76

Lung cancer. 1: prevention of lung cancer. Thorax (2002) 0.76

CT Characteristic of Early Local Recurrence After Resection of the Squamous Cell Carcinoma: Comparison With CT Characteristics of Stump Deformity or Granulation Tissue at Stump Site. Medicine (Baltimore) (2015) 0.75

The Chinese medicine JC-001 enhances the chemosensitivity of Lewis lung tumors to cisplatin by modulating the immune response. BMC Complement Altern Med (2017) 0.75

Analysis of microsatellite mutations in buccal cells from a case-control study for lung cancer. Cancer Epidemiol (2011) 0.75

Smoking and risk of myocardial infarction. Statistical and biological interactions should not be confused. BMJ (1998) 0.75

Articles by these authors

Primary structure, gene organization and polypeptide expression of poliovirus RNA. Nature (1981) 16.61

The effect of celecoxib, a cyclooxygenase-2 inhibitor, in familial adenomatous polyposis. N Engl J Med (2000) 7.54

Randomized phase III trial of docetaxel versus vinorelbine or ifosfamide in patients with advanced non-small-cell lung cancer previously treated with platinum-containing chemotherapy regimens. The TAX 320 Non-Small Cell Lung Cancer Study Group. J Clin Oncol (2000) 6.88

Head and neck cancer. N Engl J Med (1993) 6.33

The mouse Fused locus encodes Axin, an inhibitor of the Wnt signaling pathway that regulates embryonic axis formation. Cell (1997) 6.10

A randomized trial comparing perioperative chemotherapy and surgery with surgery alone in resectable stage IIIA non-small-cell lung cancer. J Natl Cancer Inst (1994) 4.21

a controlled trial of intratumoral ONYX-015, a selectively-replicating adenovirus, in combination with cisplatin and 5-fluorouracil in patients with recurrent head and neck cancer. Nat Med (2000) 4.15

The AGAMOUS-LIKE 20 MADS domain protein integrates floral inductive pathways in Arabidopsis. Genes Dev (2000) 3.90

Multi-institutional melanoma lymphatic mapping experience: the prognostic value of sentinel lymph node status in 612 stage I or II melanoma patients. J Clin Oncol (1999) 3.74

Transgenic mice expressing a human poliovirus receptor: a new model for poliomyelitis. Cell (1990) 3.70

Prevention of second primary tumors with isotretinoin in squamous-cell carcinoma of the head and neck. N Engl J Med (1990) 3.69

Differentiation therapy of acute promyelocytic leukemia with tretinoin (all-trans-retinoic acid). N Engl J Med (1991) 3.52

Everything you have ever wanted to know about Yin Yang 1...... Biochim Biophys Acta (1997) 3.48

Autofluorescence bronchoscopy in the detection of squamous metaplasia and dysplasia in current and former smokers. J Natl Cancer Inst (1998) 3.17

Retracted Non-steroidal anti-inflammatory drugs and the risk of oral cancer: a nested case-control study. Lancet (2005) 3.13

Coronectomy: a technique to protect the inferior alveolar nerve. J Oral Maxillofac Surg (2004) 3.11

Emerging invasive liver abscess caused by K1 serotype Klebsiella pneumoniae in Korea. J Infect (2006) 3.04

Reversible loss of gravitropic sensitivity in maize roots after tip application of calcium chelators. Science (1983) 3.04

Micropapillary variant of transitional cell carcinoma of the urinary bladder. Histologic pattern resembling ovarian papillary serous carcinoma. Am J Surg Pathol (1994) 3.00

Antibiotic resistance patterns of gram-negative bacteria isolated from environmental sources. Appl Environ Microbiol (1978) 3.00

Primary mucinous adenocarcinoma of the lung with signet-ring cells: a histochemical comparison with signet-ring cell carcinomas of other sites. Hum Pathol (1989) 2.97

The retinoblastoma protein acts as a transcriptional coactivator required for osteogenic differentiation. Mol Cell (2001) 2.93

Sarcomatoid differentiation in renal cell carcinoma: a study of 101 cases. Am J Surg Pathol (2001) 2.91

Effect of operative volume on morbidity, mortality, and hospital use after esophagectomy for cancer. J Thorac Cardiovasc Surg (2000) 2.88

Immunohistochemical analysis of P-glycoprotein expression correlated with chemotherapy resistance in locally advanced breast cancer. Hum Pathol (1990) 2.88

Jasmonic acid carboxyl methyltransferase: a key enzyme for jasmonate-regulated plant responses. Proc Natl Acad Sci U S A (2001) 2.84

Nilotinib vs imatinib in patients with newly diagnosed Philadelphia chromosome-positive chronic myeloid leukemia in chronic phase: ENESTnd 3-year follow-up. Leukemia (2012) 2.80

Two vivax malaria cases detected in Korea. Korean J Parasitol (1994) 2.69

Plasma levels of insulin-like growth factor-I and lung cancer risk: a case-control analysis. J Natl Cancer Inst (1999) 2.68

Complexes formed by (pyrimidine)n . (purine)n DNAs on lowering the pH are three-stranded. Nucleic Acids Res (1979) 2.62

Integrated therapy for locally advanced bladder cancer: final report of a randomized trial of cystectomy plus adjuvant M-VAC versus cystectomy with both preoperative and postoperative M-VAC. J Clin Oncol (2001) 2.56

Extraskeletal osteosarcoma. A clinicopathologic review of 26 cases. Cancer (1990) 2.56

bcl-2 and p53 oncoprotein expression during colorectal tumorigenesis. Cancer Res (1995) 2.56

Poly(pyrimidine) . poly(purine) synthetic DNAs containing 5-methylcytosine form stable triplexes at neutral pH. Nucleic Acids Res (1984) 2.55

cDNA clones coding for the heavy chain of human HLA-DR antigen. Proc Natl Acad Sci U S A (1982) 2.51

Retrovirus-mediated wild-type p53 gene transfer to tumors of patients with lung cancer. Nat Med (1996) 2.51

Thoracic sequelae and complications of tuberculosis. Radiographics (2001) 2.47

Role of auxin-induced reactive oxygen species in root gravitropism. Plant Physiol (2001) 2.45

Review: ethidium fluorescence assays. Part 1. Physicochemical studies. Nucleic Acids Res (1979) 2.42

Primary adenocarcinoma of the urinary bladder. A clinicopathologic analysis of 72 cases. Cancer (1991) 2.41

Hypermethylation of the death-associated protein (DAP) kinase promoter and aggressiveness in stage I non-small-cell lung cancer. J Natl Cancer Inst (2000) 2.39

Molecular characterization and phylogenetic studies of a wound-inducible proteinase inhibitor I gene in Lycopersicon species. Proc Natl Acad Sci U S A (1986) 2.37

Prevalence of diabetes and impaired fasting glucose in Korea: Korean National Health and Nutrition Survey 2001. Diabetes Care (2006) 2.35

Differential expression of DNA topoisomerases I and II during the eukaryotic cell cycle. Proc Natl Acad Sci U S A (1988) 2.34

Predicting cancer development in oral leukoplakia: ten years of translational research. Clin Cancer Res (2000) 2.34

Repair of tobacco carcinogen-induced DNA adducts and lung cancer risk: a molecular epidemiologic study. J Natl Cancer Inst (2000) 2.33

Expression of IL-5 in thymocytes/T cells leads to the development of a massive eosinophilia, extramedullary eosinophilopoiesis, and unique histopathologies. J Immunol (1997) 2.30

Frequent microsatellite alterations at chromosomes 9p21 and 3p14 in oral premalignant lesions and their value in cancer risk assessment. Nat Med (1996) 2.29

Is follow-up of lung cancer patients after resection medically indicated and cost-effective? Ann Thorac Surg (1995) 2.25

The product of hedgehog autoproteolytic cleavage active in local and long-range signalling. Nature (1995) 2.24

Stimulation of megakaryocyte and platelet production by a single dose of recombinant human thrombopoietin in patients with cancer. Ann Intern Med (1997) 2.22

Microbiological evaluation of Pacific shrimp processing. Appl Microbiol (1969) 2.21

Endobronchial ultrasound-guided transbronchial needle aspiration in the diagnosis of lymphoma. Thorax (2007) 2.20

Cancer mortality among cadmium production workers. Ann N Y Acad Sci (1976) 2.20

Metabolic consequences of adenosine deaminase deficiency in mice are associated with defects in alveogenesis, pulmonary inflammation, and airway obstruction. J Exp Med (2000) 2.19

Effects of N-(4-hydroxyphenyl)retinamide on hTERT expression in the bronchial epithelium of cigarette smokers. J Natl Cancer Inst (2001) 2.18

Virus-specific messenger RNAs in permissive cells infected by avian sarcoma virus. J Biol Chem (1979) 2.18

Sequence of an HLA-DR alpha-chain cDNA clone and intron-exon organization of the corresponding gene. Nature (1982) 2.18

Case-control study of the D2 dopamine receptor gene and smoking status in lung cancer patients. J Natl Cancer Inst (1998) 2.16

Human epidermal cell cultures: growth and differentiation in the absence of differentiation in the absence of dermal components or medium supplements. Proc Natl Acad Sci U S A (1979) 2.16

Mutagen sensitivity as a risk factor for second malignant tumors following malignancies of the upper aerodigestive tract. J Natl Cancer Inst (1994) 2.15

Usual interstitial pneumonia in rheumatoid arthritis-associated interstitial lung disease. Eur Respir J (2009) 2.14

Long-term impact of smoking on lung epithelial proliferation in current and former smokers. J Natl Cancer Inst (2001) 2.13

Sarcomatoid renal cell carcinoma. A treatable entity. Cancer (1987) 2.12

Identification and characterization of a novel line of Drosophila Schneider S2 cells that respond to wingless signaling. J Biol Chem (1998) 2.11