Published in Development on June 01, 1997
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A novel class of evolutionarily conserved genes defined by piwi are essential for stem cell self-renewal. Genes Dev (1998) 6.74
Specific association of Piwi with rasiRNAs derived from retrotransposon and heterochromatic regions in the Drosophila genome. Genes Dev (2006) 6.60
Specialized piRNA pathways act in germline and somatic tissues of the Drosophila ovary. Cell (2009) 6.39
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Drosophila PIWI associates with chromatin and interacts directly with HP1a. Genes Dev (2007) 3.46
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A germ cell specific gene of the ARGONAUTE family is essential for the progression of premeiotic mitosis and meiosis during sporogenesis in rice. Plant Cell (2007) 1.97
MILI, a PIWI-interacting RNA-binding protein, is required for germ line stem cell self-renewal and appears to positively regulate translation. J Biol Chem (2008) 1.93
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Drosophila Piwi functions downstream of piRNA production mediating a chromatin-based transposon silencing mechanism in female germ line. Proc Natl Acad Sci U S A (2011) 1.85
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PIWI proteins and PIWI-interacting RNAs in the soma. Nature (2014) 1.53
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Separation of stem cell maintenance and transposon silencing functions of Piwi protein. Proc Natl Acad Sci U S A (2011) 1.48
Bam and Bgcn antagonize Nanos-dependent germ-line stem cell maintenance. Proc Natl Acad Sci U S A (2009) 1.47
A conserved germline multipotency program. Development (2010) 1.42
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Identification of piRNAs in the central nervous system. RNA (2011) 1.39
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The Drosophila pumilio gene encodes two functional protein isoforms that play multiple roles in germline development, gonadogenesis, oogenesis and embryogenesis. Genetics (1999) 1.36
Pumilio facilitates miRNA regulation of the E2F3 oncogene. Genes Dev (2012) 1.36
Drosophila follicle cells: morphogenesis in an eggshell. Semin Cell Dev Biol (2008) 1.36
Pumilio 1 suppresses multiple activators of p53 to safeguard spermatogenesis. Curr Biol (2012) 1.34
The Yb body, a major site for Piwi-associated RNA biogenesis and a gateway for Piwi expression and transport to the nucleus in somatic cells. J Biol Chem (2010) 1.30
Human Pumilio proteins recruit multiple deadenylases to efficiently repress messenger RNAs. J Biol Chem (2012) 1.27
The Yb protein defines a novel organelle and regulates male germline stem cell self-renewal in Drosophila melanogaster. J Cell Biol (2009) 1.26
The Drosophila melanogaster translational repressor pumilio regulates neuronal excitability. Genetics (2002) 1.26
A Caenorhabditis elegans PUF protein family with distinct RNA binding specificity. RNA (2008) 1.25
DmGTSF1 is necessary for Piwi-piRISC-mediated transcriptional transposon silencing in the Drosophila ovary. Genes Dev (2013) 1.24
Mouse spermatogenic stem cells continually interconvert between equipotent singly isolated and syncytial states. Cell Stem Cell (2014) 1.20
The malaria parasite Plasmodium falciparum encodes members of the Puf RNA-binding protein family with conserved RNA binding activity. Nucleic Acids Res (2002) 1.17
The RNA-binding protein Musashi is required intrinsically to maintain stem cell identity. Proc Natl Acad Sci U S A (2006) 1.16
Beyond transposons: the epigenetic and somatic functions of the Piwi-piRNA mechanism. Curr Opin Cell Biol (2013) 1.16
Conservation of a Pumilio-Nanos complex from Drosophila germ plasm to human germ cells. Dev Genes Evol (2003) 1.14
A regulatory network of Drosophila germline stem cell self-renewal. Dev Cell (2014) 1.13
A conserved upstream motif orchestrates autonomous, germline-enriched expression of Caenorhabditis elegans piRNAs. PLoS Genet (2013) 1.13
PIWI Expression and Function in Cancer. Front Genet (2012) 1.12
Caenorhabditis elegans as a model for stem cell biology. Dev Dyn (2010) 1.11
shutdown is a component of the Drosophila piRNA biogenesis machinery. RNA (2012) 1.10
DjPiwi-1, a member of the PAZ-Piwi gene family, defines a subpopulation of planarian stem cells. Dev Genes Evol (2006) 1.10
The PIWI protein acts as a predictive marker for human gastric cancer. Int J Clin Exp Pathol (2012) 1.09
piRNA clusters and open chromatin structure. Mob DNA (2014) 1.08
The Drosophila cystoblast differentiation factor, benign gonial cell neoplasm, is related to DExH-box proteins and interacts genetically with bag-of-marbles. Genetics (2000) 1.08
Transition of Plasmodium sporozoites into liver stage-like forms is regulated by the RNA binding protein Pumilio. PLoS Pathog (2011) 1.06
Two Piwi proteins, Xiwi and Xili, are expressed in the Xenopus female germline. RNA (2009) 1.05
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A three-hybrid screen identifies mRNAs controlled by a regulatory protein. RNA (2006) 1.03
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Somatic and germline expression of piwi during development and regeneration in the marine polychaete annelid Capitella teleta. Evodevo (2011) 1.03
Function of Piwi, a nuclear Piwi/Argonaute protein, is independent of its slicer activity. Proc Natl Acad Sci U S A (2013) 1.00
The posterior determinant gene nanos is required for the maintenance of the adult germline stem cells during Drosophila oogenesis. Genetics (1999) 1.00
The exon junction complex controls transposable element activity by ensuring faithful splicing of the piwi transcript. Genes Dev (2014) 0.99
A PIWI homolog is one of the proteins expressed exclusively during macronuclear development in the ciliate Stylonychia lemnae. Nucleic Acids Res (2002) 0.98
Untangling the web: the diverse functions of the PIWI/piRNA pathway. Mol Reprod Dev (2013) 0.98
Drosophila Pumilio protein contains multiple autonomous repression domains that regulate mRNAs independently of Nanos and brain tumor. Mol Cell Biol (2011) 0.98
Architectural epigenetics: mitotic retention of mammalian transcriptional regulatory information. Mol Cell Biol (2010) 0.97
PUF3 acceleration of deadenylation in vivo can operate independently of CCR4 activity, possibly involving effects on the PAB1-mRNP structure. J Mol Biol (2010) 0.97
Control of signaling in a MAP-kinase pathway by an RNA-binding protein. PLoS One (2007) 0.96
HILI inhibits TGF-β signaling by interacting with Hsp90 and promoting TβR degradation. PLoS One (2012) 0.95
Slicing and Binding by Ago3 or Aub Trigger Piwi-Bound piRNA Production by Distinct Mechanisms. Mol Cell (2015) 0.95
Small noncoding RNAs in the germline. Cold Spring Harb Perspect Biol (2011) 0.94
Tinkering evolution of post-transcriptional RNA regulons: puf3p in fungi as an example. PLoS Genet (2010) 0.94
Arginine methylation of RNA-binding proteins regulates cell function and differentiation. Mol Reprod Dev (2012) 0.94
Somatic piRNA biogenesis. EMBO J (2010) 0.93
piRNA involvement in genome stability and human cancer. J Hematol Oncol (2015) 0.93
Nora virus persistent infections are not affected by the RNAi machinery. PLoS One (2009) 0.93
Drosophila piwi mutants exhibit germline stem cell tumors that are sustained by elevated Dpp signaling. Curr Biol (2013) 0.92
A eukaryotic translation initiation factor 4E-binding protein promotes mRNA decapping and is required for PUF repression. Mol Cell Biol (2012) 0.92
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Transposition of cloned P elements into Drosophila germ line chromosomes. Science (1982) 16.85
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A niche maintaining germ line stem cells in the Drosophila ovary. Science (2000) 5.04
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decapentaplegic is essential for the maintenance and division of germline stem cells in the Drosophila ovary. Cell (1998) 4.18
Preferential transposition of Drosophila P elements to nearby chromosomal sites. Genetics (1993) 3.67
The Drosophila fusome, a germline-specific organelle, contains membrane skeletal proteins and functions in cyst formation. Development (1994) 3.40
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The organization and amplification of two chromosomal domains containing Drosophila chorion genes. Cell (1981) 2.34
The Drosophila endocycle is controlled by Cyclin E and lacks a checkpoint ensuring S-phase completion. Genes Dev (1996) 2.33
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Efficient and dispersed local P element transposition from Drosophila females. Genetics (1993) 2.04
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