Published in Infect Immun on July 01, 1997
Enteroaggregative Escherichia coli. Emerg Infect Dis (1998) 1.98
Antibodies to recombinant Clostridium difficile toxins A and B are an effective treatment and prevent relapse of C. difficile-associated disease in a hamster model of infection. Infect Immun (1998) 1.63
Caspase and bid involvement in Clostridium difficile toxin A-induced apoptosis and modulation of toxin A effects by glutamine and alanyl-glutamine in vivo and in vitro. Infect Immun (2006) 1.18
Regulation of the NK-1 receptor gene expression in human macrophage cells via an NF-kappa B site on its promoter. Proc Natl Acad Sci U S A (2003) 1.15
Clostridium difficile Infection and Inflammatory Bowel Disease: A Review. Gastroenterol Res Pract (2011) 1.11
The enterotoxicity of Clostridium difficile toxins. Toxins (Basel) (2010) 1.07
Effect of novel A2A adenosine receptor agonist ATL 313 on Clostridium difficile toxin A-induced murine ileal enteritis. Infect Immun (2006) 1.05
Clostridium difficile and inflammatory bowel disease: role in pathogenesis and implications in treatment. World J Gastroenterol (2013) 1.03
The antimicrobial peptide cathelicidin modulates Clostridium difficile-associated colitis and toxin A-mediated enteritis in mice. Gut (2012) 1.02
Essential role of the glucosyltransferase activity in Clostridium difficile toxin-induced secretion of TNF-alpha by macrophages. Microb Pathog (2009) 0.99
Clostridium difficile toxins A and B directly stimulate human mast cells. Infect Immun (2007) 0.97
Human monoclonal antibodies against Clostridium difficile toxins A and B inhibit inflammatory and histologic responses to the toxins in human colon and peripheral blood monocytes. Antimicrob Agents Chemother (2013) 0.89
Effects of toxin A from Clostridium difficile on mast cell activation and survival. Infect Immun (1998) 0.86
MAPK-activated protein kinase 2 contributes to Clostridium difficile-associated inflammation. Infect Immun (2012) 0.85
Down-regulation of interleukin-16 in human mast cells HMC-1 by Clostridium difficile toxins A and B. Naunyn Schmiedebergs Arch Pharmacol (2011) 0.84
The roles of host and pathogen factors and the innate immune response in the pathogenesis of Clostridium difficile infection. Mol Immunol (2014) 0.81
Intestinal secretory factor released by macrophages stimulated with Clostridium difficile toxin A: role of interleukin 1beta. Infect Immun (1998) 0.80
The expression of cytokine genes in the peritoneal macrophages and splenic CD4- and CD8-positive lymphocytes of the nonobese diabetic mice. J Clin Immunol (2004) 0.79
The pharmacological profile of ovalbumin-induced paw oedema in rats. Mediators Inflamm (2002) 0.78
Glutamine depletion potentiates leucocyte-dependent inflammatory events induced by carrageenan or Clostridium difficile toxin A in rats. Immunology (2005) 0.78
Clostridium difficile infection in patients with inflammatory bowel disease. Prz Gastroenterol (2014) 0.77
Clostridium difficile-induced colitis in mice is independent of leukotrienes. Anaerobe (2014) 0.75
Clostridium difficile toxin B differentially affects GPCR-stimulated Ca2+ responses in macrophages: independent roles for Rho and PLA2. J Leukoc Biol (2010) 0.75
Clostridium difficile colitis. N Engl J Med (1994) 9.31
Leukotriene B, a potent chemokinetic and aggregating substance released from polymorphonuclear leukocytes. Nature (1980) 9.25
Clostridium difficile: its disease and toxins. Clin Microbiol Rev (1988) 7.26
Studies on the mediators of the acute inflammatory response induced in rats in different sites by carrageenan and turpentine. J Pathol (1971) 6.97
Purification and characterization of toxins A and B of Clostridium difficile. Infect Immun (1982) 6.88
Effects of Clostridium difficile toxins given intragastrically to animals. Infect Immun (1985) 5.44
Comparison of two toxins produced by Clostridium difficile. Infect Immun (1981) 5.16
Biological activities of toxins A and B of Clostridium difficile. Infect Immun (1982) 4.62
Mast cells as a source of both preformed and immunologically inducible TNF-alpha/cachectin. Nature (1990) 4.21
Molecular characterization of the Clostridium difficile toxin A gene. Infect Immun (1990) 4.06
The formation of a structure with the features of synovial lining by subcutaneous injection of air: an in vivo tissue culture system. J Pathol (1981) 3.99
New concepts about the mast cell. N Engl J Med (1993) 3.43
Nucleotide sequence of Clostridium difficile toxin B gene. Nucleic Acids Res (1990) 2.93
Neuronal involvement in the intestinal effects of Clostridium difficile toxin A and Vibrio cholerae enterotoxin in rat ileum. Gastroenterology (1994) 2.28
Biochemical characterization and biologic actions of two toxins (D-1 and D-2) from Clostridium difficile. Rev Infect Dis (1984) 2.26
CP-96,345, a substance P antagonist, inhibits rat intestinal responses to Clostridium difficile toxin A but not cholera toxin. Proc Natl Acad Sci U S A (1994) 2.22
Endotoxin, septic shock and acute lung injury: neutrophils, macrophages and inflammatory mediators. Br J Surg (1992) 2.13
Increased inflammatory reactivity in newly formed lining tissue. J Pathol (1983) 2.01
Cytokine response by human monocytes to Clostridium difficile toxin A and toxin B. Infect Immun (1991) 1.87
Recombinant interleukin-1 and tumor necrosis factor induce neutrophil migration "in vivo" by indirect mechanisms. Agents Actions (1990) 1.71
Neutrophil recruitment by tumor necrosis factor from mast cells in immune complex peritonitis. Science (1992) 1.62
Clostridium difficile toxin A and its effects on cells. Toxicon (1991) 1.54
IL-8 causes in vivo neutrophil migration by a cell-dependent mechanism. Immunology (1991) 1.54
Anti-inflammatory drugs, prostaglandins and leucocyte migration. Agents Actions (1976) 1.45
Blockade by antimacrophage serum of the migration of PMN neutrophils into the inflamed peritoneal cavity. Agents Actions (1985) 1.45
Indomethacin inhibition of Salmonella typhimurium, Shigella flexneri, and cholera-mediated rabbit ileal secretion. J Infect Dis (1974) 1.44
Clostridium difficile toxin A stimulates intracellular calcium release and chemotactic response in human granulocytes. J Clin Invest (1988) 1.41
Ketotifen inhibits Clostridium difficile toxin A-induced enteritis in rat ileum. Gastroenterology (1993) 1.36
Comparative study of Clostridium difficile toxin A and cholera toxin in rabbit ileum. Gastroenterology (1989) 1.30
Clostridium difficile colitis and diarrhea. Gastroenterol Clin North Am (1993) 1.19
Macrophage-dependent stimulation of T cell-depleted spleen cells by Clostridium difficile toxin A and calcium ionophore. Cell Immunol (1990) 1.15
Neutrophil migration induced by inflammatory stimuli is reduced by macrophage depletion. Agents Actions (1988) 1.13
The release of a neutrophil chemotactic factor from peritoneal macrophages by endotoxin: inhibition by glucocorticoids. Eur J Pharmacol (1986) 1.12
Chemotactic and mitogenic components of the alveolar macrophage response to particles ad neutrophil chemoattractant. Am J Pathol (1982) 1.09
Nitric oxide inhibits rat intestinal secretion by Clostridium difficile toxin A but not Vibrio cholerae enterotoxin. Gastroenterology (1996) 0.98
The subcutaneous air pouch model of synovium and the inflammatory response to heat aggregated gammaglobulin. Agents Actions (1986) 0.98
Enhanced production of monokines by canine alveolar macrophages in response to endotoxin-induced shock. Proc Soc Exp Biol Med (1988) 0.96
Recombinant gamma interferon causes neutrophil migration mediated by the release of a macrophage neutrophil chemotactic factor. Int J Exp Pathol (1990) 0.94
Role of platelet activating factor in the inflammatory and secretory effects of Clostridium difficile toxin A. J Lipid Mediat Cell Signal (1995) 0.87
Clostridium difficile toxin A. Interactions with mucus and early sequential histopathologic effects in rabbit small intestine. Lab Invest (1989) 0.84
Failure of PAF-acether to induce in vivo neutrophil migration. Agents Actions (1988) 0.78
Cyclic adenosine monophosphate and alteration of Chinese hamster ovary cell morphology: a rapid, sensitive in vitro assay for the enterotoxins of Vibrio cholerae and Escherichia coli. Infect Immun (1974) 12.51
Effects of Clostridium difficile toxins given intragastrically to animals. Infect Immun (1985) 5.44
Induction of a novel morphological response in Chinese hamster ovary cells by pertussis toxin. Infect Immun (1983) 5.03
Biological activities of toxins A and B of Clostridium difficile. Infect Immun (1982) 4.62
Campylobacteriosis in man: pathogenic mechanisms and review of 91 bloodstream infections. Am J Med (1978) 4.56
Role of toxigenic and invasive bacteria in acute diarrhea of childhood. N Engl J Med (1975) 4.23
Molecular characterization of the Clostridium difficile toxin A gene. Infect Immun (1990) 4.06
Prospective study of diarrheal illnesses in northeastern Brazil: patterns of disease, nutritional impact, etiologies, and risk factors. J Infect Dis (1983) 3.65
Role of cyclic GMP in the action of heat-stable enterotoxin of Escherichia coli. Nature (1978) 3.60
Role of adherence in cytopathogenic mechanisms of Entamoeba histolytica. Study with mammalian tissue culture cells and human erythrocytes. J Clin Invest (1981) 3.50
Enzyme-linked immunosorbent assay for Clostridium difficile toxin A. J Clin Microbiol (1983) 3.40
Association of early childhood diarrhea and cryptosporidiosis with impaired physical fitness and cognitive function four-seven years later in a poor urban community in northeast Brazil. Am J Trop Med Hyg (1999) 3.25
Cytopathogenic mechanisms of Entamoeba histolytica. J Exp Med (1980) 3.06
Urea protects Helicobacter (Campylobacter) pylori from the bactericidal effect of acid. Gastroenterology (1990) 3.04
Epidemic diarrhea at Crater Lake from enterotoxigenic Escherichia coli. A large waterborne outbreak. Ann Intern Med (1977) 2.80
Household epidemiology of Cryptosporidium parvum infection in an urban community in northeast Brazil. Ann Intern Med (1994) 2.66
Enteroaggregative Escherichia coli produce intestinal inflammation and growth impairment and cause interleukin-8 release from intestinal epithelial cells. J Infect Dis (1998) 2.59
Activation of intestinal guanylate cyclase by heat-stable enterotoxin of Escherichia coli: studies of tissue specificity, potential receptors, and intermediates. J Infect Dis (1980) 2.52
Intestinal adenyl-cyclase activity in canine cholera: correlation with fluid accumulation. J Infect Dis (1972) 2.46
Monoclonal and specific polyclonal antibodies for immunoassay of Clostridium difficile toxin A. J Clin Microbiol (1985) 2.46
Interaction between Entamoeba histolytica and human polymorphonuclear neutrophils. J Infect Dis (1981) 2.26
Effect of Escherichia coli on fluid transport across canine small bowel. Mechanism and time-course with enterotoxin and whole bacterial cells. J Clin Invest (1973) 2.25
Diarrhoea and catch-up growth. Lancet (1990) 2.24
Measurement of fecal lactoferrin as a marker of fecal leukocytes. J Clin Microbiol (1992) 2.12
The enterotoxin of Bacteroides fragilis is a metalloprotease. Infect Immun (1995) 2.06
Persistent diarrhea signals a critical period of increased diarrhea burdens and nutritional shortfalls: a prospective cohort study among children in northeastern Brazil. J Infect Dis (2000) 2.01
Characterization of toxins A and B of Clostridium difficile with monoclonal antibodies. Infect Immun (1986) 2.01
Effects of Clostridium difficile toxins A and B in rabbit small and large intestine in vivo and on cultured cells in vitro. Infect Immun (1988) 2.00
Enteroaggregative Escherichia coli. Emerg Infect Dis (1998) 1.98
Purification and characterization of an enterotoxin from Bacteroides fragilis. Infect Immun (1992) 1.97
Enteroaggregative Escherichia coli expresses a novel flagellin that causes IL-8 release from intestinal epithelial cells. J Clin Invest (2000) 1.96
Entamoeba histolytica and Entamoeba dispar infection in children in Bangladesh. J Infect Dis (1997) 1.95
Commercial latex test for Clostridium difficile toxin A does not detect toxin A. J Clin Microbiol (1986) 1.92
Early childhood diarrhoea and helminthiases associate with long-term linear growth faltering. Int J Epidemiol (2001) 1.85
Etiology and epidemiology of persistent diarrhea in northeastern Brazil: a hospital-based, prospective, case-control study. J Pediatr Gastroenterol Nutr (1995) 1.82
Protozoal agents: what are the dangers for the public water supply? Annu Rev Med (1997) 1.80
Potential role of adherence traits of Escherichia coli in persistent diarrhea in an urban Brazilian slum. Pediatr Infect Dis J (1991) 1.75
Multicenter evaluation of a new screening test that detects Clostridium difficile in fecal specimens. J Clin Microbiol (2004) 1.71
Metronidazole susceptibility testing for Helicobacter pylori: comparison of disk, broth, and agar dilution methods and their clinical relevance. J Clin Microbiol (1993) 1.70
Fecal lactoferrin, interleukin-1beta, and interleukin-8 are elevated in patients with severe Clostridium difficile colitis. Clin Diagn Lab Immunol (1997) 1.68
N-Acetyl-D-galactosamine-inhibitable adherence lectin of Entamoeba histolytica. I. Partial purification and relation to amoebic virulence in vitro. J Infect Dis (1985) 1.67
Deletions in the repeating sequences of the toxin A gene of toxin A-negative, toxin B-positive Clostridium difficile strains. FEMS Microbiol Lett (1999) 1.66
Longitudinal study of Cryptosporidium infection in children in northeastern Brazil. J Infect Dis (1999) 1.64
Proteolytic activity of the Bacteroides fragilis enterotoxin causes fluid secretion and intestinal damage in vivo. Infect Immun (1995) 1.59
Efficacy of a glutamine-based oral rehydration solution on the electrolyte and water absorption in a rabbit model of secretory diarrhea induced by cholera toxin. J Pediatr Gastroenterol Nutr (1998) 1.58
Toxins of Vibrio cholerae and Escherichia coli stimulate adenyl cyclase in rat fat cells. Nature (1974) 1.58
Value of examination for fecal leukocytes in the early diagnosis of shigellosis. Am J Trop Med Hyg (1979) 1.57
Adherence of Entamoeba histolytica trophozoites to rat and human colonic mucosa. Infect Immun (1985) 1.50
Effects of Escherichia coli heat-stable enterotoxin STb on intestines of mice, rats, rabbits, and piglets. Infect Immun (1984) 1.49
Prevalence of Campylobacter species, Helicobacter pylori and Arcobacter species in stool samples from the Venda region, Limpopo, South Africa: studies using molecular diagnostic methods. J Infect (2006) 1.47
Comparative pharmacology of josamycin and erythromycin stearate. Antimicrob Agents Chemother (1976) 1.46
High frequency of strains multiply resistant to ampicillin, trimethoprim-sulfamethoxazole, streptomycin, chloramphenicol, and tetracycline isolated from patients with shigellosis in northeastern Brazil during the period 1988 to 1993. Antimicrob Agents Chemother (1995) 1.45
Toxigenic bacterial diarrhea: nursery outbreak involving multiple bacterial strains. J Pediatr (1976) 1.44
Cryptosporidium species: preliminary descriptions of the prevalence and genotype distribution among school children and hospital patients in the Venda region, Limpopo Province, South Africa. Exp Parasitol (2006) 1.43
Selective surveillance for nosocomial infections in a Brazilian hospital. Infect Control Hosp Epidemiol (1993) 1.43
A 20-minute breath test for helicobacter pylori. Am J Gastroenterol (1991) 1.43
In vivo and in vitro effects of a novel enterotoxin, STb, produced by Escherichia coli. J Infect Dis (1986) 1.41
Regulation of intestinal epithelial barrier function by TGF-beta 1. Evidence for its role in abrogating the effect of a T cell cytokine. J Immunol (1994) 1.39
Evaluation of formalin-inactivated Clostridium difficile vaccines administered by parenteral and mucosal routes of immunization in hamsters. Infect Immun (1995) 1.35
Production of type II heat-labile enterotoxin by Escherichia coli isolated from food and human feces. Infect Immun (1986) 1.35
Small-bowel colonization alone is a cause of diarrhea. Infect Immun (1987) 1.35
Diminished neutrophil oxidative metabolism after phagocytosis of virulent Salmonella typhi. Infect Immun (1981) 1.34
Comparison of culture, cytotoxicity assays, and enzyme-linked immunosorbent assay for toxin A and toxin B in the diagnosis of Clostridium difficile-related enteric disease. Diagn Microbiol Infect Dis (1986) 1.34
Characterization of the Chinese hamster ovary cell assay for the enterotoxins of Vibrio cholerae and Escherichia coli and for specific antisera, and toxoid. J Infect Dis (1977) 1.33
Evaluation of an antigen capture enzyme-linked immunosorbent assay for detection of Cryptosporidium oocysts. J Clin Microbiol (1993) 1.32
Cryptosporidiosis: an update. Lancet Infect Dis (2001) 1.32
Evaluation and diagnosis of acute infectious diarrhea. Am J Med (1985) 1.32
Giardia lamblia infection of suckling mice. J Infect Dis (1983) 1.29
Genetic characterization of toxin A-negative, toxin B-positive Clostridium difficile isolates by PCR. J Clin Microbiol (2000) 1.28
A review of the parasite cellular mechanisms involved in the pathogenesis of amebiasis. Rev Infect Dis (1983) 1.28
Reversible atrioventricular block in myxedema. Chest (1973) 1.24
A rapid test for infectious and inflammatory enteritis. Arch Intern Med (1995) 1.23
Feasibility and efficacy of in-home water chlorination in rural North-eastern Brazil. J Hyg (Lond) (1985) 1.23
A prospective study of persistent diarrhea among children in an urban Brazilian slum. Patterns of occurrence and etiologic agents. Am J Epidemiol (1990) 1.23
STb enterotoxin of Escherichia coli: cyclic nucleotide-independent secretion. Ciba Found Symp (1985) 1.23
Characterization of binding of Escherichia coli strains which are enteropathogens to small-bowel mucin. Infect Immun (1990) 1.23
Cryptosporidiosis in northeastern Brazil: association with sporadic diarrhea. J Infect Dis (1985) 1.22
Infection and immunity mediated by the carbohydrate recognition domain of the Entamoeba histolytica Gal/GalNAc lectin. J Infect Dis (1999) 1.22
Importance of serratia protease in the pathogenesis of experimental Serratia marcescens pneumonia. Infect Immun (1983) 1.22
Reduction of the secretory response to Escherichia coli heat-stable enterotoxin by thiol and disulfide compounds. Infect Immun (1983) 1.21
Social, behavioral, and practical factors affecting antibiotic use worldwide: report of Task Force 4. Rev Infect Dis (1987) 1.21
Fecal screening tests in the approach to acute infectious diarrhea: a scientific overview. Pediatr Infect Dis J (1996) 1.20
Murine model of Clostridium difficile infection with aged gnotobiotic C57BL/6 mice and a BI/NAP1 strain. J Infect Dis (2010) 1.19
Persistent diarrhea in children: epidemiology, risk factors, pathophysiology, nutritional impact, and management. Epidemiol Rev (1992) 1.18
Net fluid secretion and impaired villous function induced by colonization of the small intestine by nontoxigenic colonizing Escherichia coli. Infect Immun (1990) 1.17
High frictional anisotropy of periodic and aperiodic directions on a quasicrystal surface. Science (2005) 1.17
Effect of antagonists of calcium and phospholipase A on the cytopathogenicity of Entamoeba histolytica. J Infect Dis (1985) 1.17
Prevalence of intestinal parasitic and bacterial pathogens in diarrhoeal and non-diarroeal human stools from Vhembe district, South Africa. J Health Popul Nutr (2009) 1.17