1
|
A review of the plants of the genus Phyllanthus: their chemistry, pharmacology, and therapeutic potential.
|
Med Res Rev
|
1998
|
1.90
|
2
|
Naturally occurring antinociceptive substances from plants.
|
Phytother Res
|
2000
|
1.63
|
3
|
Antinociceptive activity of I3,II8-binaringenin, a biflavonoid present in plants of the guttiferae.
|
Planta Med
|
2000
|
1.54
|
4
|
Further studies on analgesic activity of cyclic imides.
|
Farmaco
|
1998
|
1.18
|
5
|
Analgesic effects of callus culture extracts from selected species of Phyllanthus in mice.
|
J Pharm Pharmacol
|
1994
|
1.18
|
6
|
Antibacterial activity and phytochemical analysis of Vochysia divergens (Vochysiaceae).
|
J Ethnopharmacol
|
1995
|
1.01
|
7
|
A sesquiterpene drimane with antinociceptive activity from Drimys winteri bark.
|
Phytochemistry
|
2001
|
0.96
|
8
|
Antinociceptive action of 2-(4-bromobenzoyl)-3-methyl-4,6-dimethoxy benzofuran, a novel xanthoxyline derivative on chemical and thermal models of nociception in mice.
|
J Pharmacol Exp Ther
|
1996
|
0.96
|
9
|
Antinociceptive properties of the new alkaloid, cis-8, 10-di-N-propyllobelidiol hydrochloride dihydrate isolated from Siphocampylus verticillatus: evidence for the mechanism of action.
|
J Pharmacol Exp Ther
|
1999
|
0.95
|
10
|
Analgesic potential of marrubiin derivatives, a bioactive diterpene present in Marrubium vulgare (Lamiaceae).
|
Farmaco
|
2005
|
0.94
|
11
|
Study of the antinociceptive action of the ethanolic extract and the triterpene 24-hydroxytormentic acid isolated from the stem bark of Ocotea suaveolens.
|
Planta Med
|
1999
|
0.93
|
12
|
Chemical composition and antimicrobial activity of Croton urucurana Baillon (Euphorbiaceae).
|
J Ethnopharmacol
|
1997
|
0.91
|
13
|
The selective antagonism of bradykinin action on rat isolated uterus by crude Mandevilla velutina extract.
|
Br J Pharmacol
|
1985
|
0.91
|
14
|
Chemical and pharmacological examination of antinociceptive constituents of Wedelia paludosa.
|
J Ethnopharmacol
|
1998
|
0.91
|
15
|
Chemical and preliminary analgesic evaluation of geraniin and furosin isolated from Phyllanthus sellowianus.
|
Planta Med
|
1996
|
0.89
|
16
|
Effect of crude extracts from Leonotis nepetaefolia (Labiatae) on rat and guinea-pig smooth muscle and rat cardiac muscle.
|
J Pharm Pharmacol
|
1991
|
0.88
|
17
|
Additional evidence for the anti-inflammatory and anti-allergic properties of the sesquiterpene polygodial.
|
Life Sci
|
2001
|
0.88
|
18
|
Antinociceptive properties of the methanolic extract and two triterpenes isolated from Epidendrum Mosenii stems (Orchidaceae).
|
Life Sci
|
2000
|
0.88
|
19
|
Anti-hyperalgesic properties of the extract and of the main sesquiterpene polygodial isolated from the barks of Drymis winteri (Winteraceae).
|
Life Sci
|
1998
|
0.87
|
20
|
Antispasmodic effects of an alkaloid extracted from Phyllanthus sellowianus: a comparative study with papaverine.
|
Braz J Med Biol Res
|
1984
|
0.87
|
21
|
Relation between lipophilicity of alkyl gallates and antifungal activity against yeasts and filamentous fungi.
|
Bioorg Med Chem Lett
|
2009
|
0.86
|
22
|
Antinociceptive properties of the methanolic extract obtained from Ipomoea pes-caprae (L.) R. Br.
|
J Ethnopharmacol
|
2000
|
0.85
|
23
|
Phytochemical analysis and analgesic properties of Curcuma zedoaria grown in Brazil.
|
Phytomedicine
|
2002
|
0.85
|
24
|
Analgesic triterpenes from Sebastiania schottiana roots.
|
Phytomedicine
|
1999
|
0.84
|
25
|
Assessment of mechanisms involved in antinociception caused by sesquiterpene polygodial.
|
J Pharmacol Exp Ther
|
2000
|
0.84
|
26
|
Quantitative structure-odor relationships of aliphatic esters using topological indices.
|
J Agric Food Chem
|
2000
|
0.83
|
27
|
Antifungal activity of sterols and triterpenes isolated from Ganoderma annulare.
|
Fitoterapia
|
2003
|
0.83
|
28
|
Isolation and identification of compounds with antinociceptive action from Ipomoea pes-caprae (L.) R. Br.
|
Pharmazie
|
1999
|
0.82
|
29
|
Antinociceptive activity of niga-ichigoside F1 from Rubus imperialis.
|
J Nat Prod
|
1999
|
0.82
|
30
|
Isolation of biflavonoids with analgesic activity from Rheedia gardneriana leaves.
|
Phytomedicine
|
1997
|
0.82
|
31
|
Antinociceptive and anti-oedematogenic properties of astilbin, taxifolin and some related compounds.
|
Arzneimittelforschung
|
2000
|
0.82
|
32
|
Isolation and identification of active compounds from Drimys winteri barks.
|
J Ethnopharmacol
|
1998
|
0.81
|
33
|
Analysis of the mechanisms underlying the antinociceptive effect of the extracts of plants from the genus Phyllanthus.
|
Gen Pharmacol
|
1995
|
0.81
|
34
|
The competitive antagonistic effect of compounds from Mandevilla velutina on kinin-induced contractions of rat uterus and guinea-pig ileum in vitro.
|
Br J Pharmacol
|
1988
|
0.81
|
35
|
Isolation of a C-Glycoside Flavonoid with Antinociceptive Action from Aleurites moluccana Leaves.
|
Planta Med
|
1999
|
0.81
|
36
|
Kinin antagonist activity of compounds from Mandevilla velutina in the rat isolated uterus.
|
Br J Pharmacol
|
1987
|
0.81
|
37
|
Chemical composition and analgesic activity of Calophyllum brasiliense leaves.
|
Therapie
|
2001
|
0.81
|
38
|
Evidence for the involvement of glutamatergic receptors in the antinociception caused in mice by the sesquiterpene drimanial.
|
Neuropharmacology
|
2002
|
0.80
|
39
|
Mechanisms underlying the relaxation caused by the sesquiterpene polygodial in vessels from rabbit and guinea-pig.
|
Eur J Pharmacol
|
1999
|
0.80
|
40
|
Antinociception caused by the extract of Hedyosmum brasiliense and its active principle, the sesquiterpene lactone 13-hydroxy-8,9-dehydroshizukanolide.
|
Planta Med
|
1999
|
0.80
|
41
|
Semi-empirical topological method for the prediction of the chromatographic retention of cis- and trans-alkene isomers and alkanes.
|
J Chromatogr A
|
1999
|
0.80
|
42
|
Antinociceptive properties of extracts of new species of plants of the genus Phyllanthus (Euphorbiaceae).
|
J Ethnopharmacol
|
2000
|
0.80
|
43
|
Action of polygodial on agonist-induced contractions of the rat portal vein in vitro.
|
J Cardiovasc Pharmacol
|
2000
|
0.80
|
44
|
Potent antinociceptive activity of a hydroalcoholic extract of Phyllanthus corcovadensis.
|
J Pharm Pharmacol
|
1993
|
0.79
|
45
|
Triterpenes from the resin of Protium heptaphyllum.
|
Fitoterapia
|
2001
|
0.79
|
46
|
Correlation of activity of 2-(X-benzyloxy)-4,6-dimethoxyacetophenones with topological indices and with the Hansch equation.
|
Farmaco
|
1999
|
0.79
|
47
|
The involvement of K+ channels and Gi/o protein in the antinociceptive action of the gallic acid ethyl ester.
|
Eur J Pharmacol
|
1999
|
0.79
|
48
|
Antifungal activity of fractions and two pure compounds of flowers from Wedelia paludosa (Acmela brasiliensis) (Asteraceae).
|
Pharmazie
|
2003
|
0.78
|
49
|
Filicene obtained from Adiantum cuneatum interacts with the cholinergic, dopaminergic, glutamatergic, GABAergic, and tachykinergic systems to exert antinociceptive effect in mice.
|
Pharmacol Biochem Behav
|
2009
|
0.78
|
50
|
Hypolipidaemic activity of methanol extract of Aleurites moluccana.
|
Phytother Res
|
2002
|
0.78
|
51
|
Two new 11alpha,12alpha-epoxy-ursan-28,13beta-olides and other triterpenes from Cecropia catharinensis.
|
Nat Prod Res
|
2008
|
0.78
|
52
|
Effect of a crude extract of Mandevilla velutina on contractions induced by bradykinin and [des-Arg9]-bradykinin in isolated vessels of the rabbit.
|
Br J Pharmacol
|
1986
|
0.78
|
53
|
Analysis of the mechanisms underlying the contractile response induced by the hydroalcoholic extract of Phyllanthus urinaria in the guinea-pig urinary bladder in-vitro.
|
J Pharm Pharmacol
|
1995
|
0.78
|
54
|
Anti-allergic effects and oedema inhibition caused by the extract of Drymis winteri.
|
Inflamm Res
|
1997
|
0.78
|
55
|
Antibacterial activity of N-phenylmaleimides, N-phenylsuccinimides and related compounds. Structure-activity relationships.
|
Farmaco
|
1994
|
0.78
|
56
|
Antinociceptive action of extracts and fractions from Rubus imperialis (Rosaceae).
|
Therapie
|
2002
|
0.77
|
57
|
Chemical and pharmacological studies of Phyllanthus caroliniensis in mice.
|
J Pharm Pharmacol
|
1996
|
0.77
|
58
|
A circular dichroism study of the structure of Apis mellifera melittin.
|
Arch Biochem Biophys
|
1982
|
0.77
|
59
|
Phytochemical and pharmacognositc investigation of Bauhinia forficata Link (Leguminosae).
|
Z Naturforsch C
|
2000
|
0.77
|
60
|
Pharmacological activity and chemical composition of callus culture extracts from selected species of Phyllanthus.
|
Pharmazie
|
2000
|
0.77
|
61
|
Effect of compounds from Mandevilla velutina on bradykinin-mediated contractile and relaxant responses of the isolated guinea pig trachea.
|
Agents Actions
|
1992
|
0.77
|
62
|
Antagonism of kinin-induced contraction of isolated rat uterus by the crude hydroalcoholic extract from Mandevilla illustris.
|
Gen Pharmacol
|
1991
|
0.77
|
63
|
Action of polygodial, a sesquiterpene isolated from Drymis winteri, in the guinea-pig ileum and trachea 'in vitro'.
|
Eur J Pharmacol
|
1998
|
0.77
|
64
|
Antinociceptive properties of steroids isolated from Phyllanthus corcovadensis in mice.
|
Planta Med
|
1995
|
0.77
|
65
|
Mechanisms involved in the contractile responses induced by the hydroalcoholic extract of Phyllanthus urinaria on the guinea pig isolated trachea: evidence for participation of tachykinins and influx of extracellular Ca2+ sensitive to ruthenium red.
|
Gen Pharmacol
|
1996
|
0.77
|
66
|
Preliminary phytochemical and pharmacological studies of Aleurites moluccana leaves [L.] Willd.
|
Phytomedicine
|
1998
|
0.77
|
67
|
Antinociceptive properties of the hydroalcoholic extract and preliminary study of a xanthone isolated from Polygala cyparissias (Polygalaceae).
|
Life Sci
|
1997
|
0.77
|
68
|
Structure-activity relationships for the analgesic activity of gallic acid derivatives.
|
Farmaco
|
2001
|
0.77
|
69
|
Pharmacological and phytochemical investigations of different parts of Calophyllum brasiliense (Clusiaceae).
|
Pharmazie
|
2004
|
0.76
|
70
|
The relaxant effect of extract of Phyllanthus urinaria in the guinea-pig isolated trachea. Evidence for involvement of ATP-sensitive potassium channels.
|
J Pharm Pharmacol
|
1996
|
0.76
|
71
|
Chemical and pharmacological studies on Talauma ovata St. Hil. (Magnoliaceae).
|
J Ethnopharmacol
|
1989
|
0.76
|
72
|
I3-naringenin-II8--4'OMe-eriodictyol: a new potential analgesic agent isolated from Rheedia gardneriana leaves.
|
Z Naturforsch C
|
2001
|
0.76
|
73
|
Phytochemical and pharmacological analysis of Bauhinia microstachya (Raddi) Macbr. (Leguminosae).
|
Z Naturforsch C
|
2002
|
0.76
|
74
|
Differential effects of Mandevilla velutina compounds on paw oedema induced by phospholipase A2 and phospholipase C.
|
Eur J Pharmacol
|
1993
|
0.76
|
75
|
A triterpene and phenolic compounds from leaves and stems of Phyllanthus sellowianus.
|
Planta Med
|
1995
|
0.75
|
76
|
Phyllanthimide, a new alkaloid from Phyllanthus sellowianus.
|
J Nat Prod
|
1988
|
0.75
|
77
|
Extract and compounds obtained from Mandevilla velutina inhibit arachidonic acid-induced ear oedema in mice, but not rat stomach contraction.
|
Prostaglandins
|
1991
|
0.75
|
78
|
Inhibition of rat paw oedema and pleurisy by the extract from Mandevilla velutina.
|
Agents Actions
|
1991
|
0.75
|
79
|
The mechanisms underlying the relaxant effect of methyl and ethyl gallates in the guinea pig trachea in vitro: contribution of potassium channels.
|
Naunyn Schmiedebergs Arch Pharmacol
|
1999
|
0.75
|
80
|
Triterpenes from Phyllanthus sellowianus roots.
|
Planta Med
|
1998
|
0.75
|
81
|
Structure-activity relationships for a collection of structurally diverse inhibitors of purine nucleoside phosphorylase.
|
Chem Pharm Bull (Tokyo)
|
2001
|
0.75
|
82
|
Antinociceptive activity of a hydroalcoholic extract obtained from aerial parts of Sebastiania schottiana (Euphorbiaceae).
|
Pharmazie
|
2000
|
0.75
|
83
|
Action of pregnane compounds from Mandevilla illustris against contractions induced by kinins and other oxytocics in the rat isolated uterus.
|
Gen Pharmacol
|
1991
|
0.75
|
84
|
Separation of biflavonoids from Rheedia gardneriana using chitin-Fe complex as stationary phase.
|
Pharmazie
|
2000
|
0.75
|
85
|
Antispasmodic activity of xanthoxyline derivatives: structure-activity relationships.
|
J Pharm Sci
|
1995
|
0.75
|
86
|
In vitro effect of the extract and the 1,7-dihydroxy-2,3-dimethoxy xanthone from Polygala cyparissias on the contractions induced by inflammatory mediators and ovalbumin in normal and actively sensitised trachea from guinea pig.
|
Inflamm Res
|
1999
|
0.75
|
87
|
Action of 2-hydroxy-4,6-dimethoxyacetophenone isolated from Sebastiania schottiana.
|
Planta Med
|
1990
|
0.75
|
88
|
Phytochemical and pharmacological investigations of Virola oleifera leaves.
|
Z Naturforsch C
|
2001
|
0.75
|
89
|
A comparative chemical study of Maytenus ilicifolia mart. reiss and Maytenus robusta reiss (Celastraceae).
|
Z Naturforsch C
|
2001
|
0.75
|
90
|
Blockade of kinin-induced responses of the guinea-pig isolated urinary bladder by the extract of Mandevilla velutina.
|
Gen Pharmacol
|
1990
|
0.75
|
91
|
Development of a predictive statistical model for the analgesic activity of a family of imides.
|
Pharmazie
|
1999
|
0.75
|
92
|
Evaluation of the antinociceptive action caused by ether fraction and a triterpene isolated from resin of Protium kleinii.
|
Life Sci
|
2001
|
0.75
|
93
|
Analgesic compounds from Epidendrum mosenii stems.
|
Pharmazie
|
1998
|
0.75
|
94
|
Blockade of the bradykinin-evoked diphasic response of isolated rat duodenum by the crude extract of and compounds obtained from Mandevilla velutina.
|
Braz J Med Biol Res
|
1988
|
0.75
|
95
|
Natural bradykinin antagonists.
|
Mem Inst Oswaldo Cruz
|
1991
|
0.75
|
96
|
Antinociceptive properties of morusin, a prenylflavonoid isolated from Morus nigra root bark.
|
Z Naturforsch C
|
2000
|
0.75
|
97
|
Action of the extract of Drymis winteri on contraction induced by inflammatory mediators, compound 48/80 and ovalbumin of the guinea-pig trachea in vitro.
|
Gen Pharmacol
|
1997
|
0.75
|
98
|
Fungicide and fungiostatic effects of xanthoxyline.
|
J Ethnopharmacol
|
1996
|
0.75
|
99
|
Demonstration of anti-bradykinin compounds in callus cultures of Mandevilla velutina.
|
Braz J Med Biol Res
|
1989
|
0.75
|
100
|
Compounds extracted from Phyllantus and Jatropha elliptica inhibit the binding of [3H]glutamate and [3H]GMP-PNP in rat cerebral cortex membrane.
|
Neurochem Res
|
2000
|
0.75
|
101
|
Analgesic activity of cyclic imides: 1,8-naphthalimide and 1,4,5,8-naphthalenediimide derivatives.
|
Farmaco
|
2000
|
0.75
|
102
|
In vitro antifungal evaluation and studies on the mode of action of xanthoxyline derivatives.
|
Arzneimittelforschung
|
1999
|
0.75
|
103
|
Pharmacological analysis of the methanolic extract and sorocein A, a new Diels-Alder compound isolated from the roots of Sorocea bonplandii Bailon in the isolated rat uterus and guinea pig ileum.
|
Gen Pharmacol
|
1993
|
0.75
|
104
|
Antinociceptive properties of N-aryl-glutaramic acids and N-aryl-glutarimides.
|
Pharmazie
|
2000
|
0.75
|
105
|
Effects of Sebastiana schottiana extracts on isolated smooth muscle contraction.
|
Planta Med
|
1986
|
0.75
|
106
|
Mechanisms involved in the antinociceptive effect in mice of the hydroalcoholic extract of Siphocampylus verticillatus.
|
J Pharm Pharmacol
|
1997
|
0.75
|
107
|
Antagonistic effect of Mandevilla velutina extract on kinin-induced contractions of guinea-pig and cat ileum longitudinal smooth muscle.
|
Gen Pharmacol
|
1988
|
0.75
|
108
|
Analgesic activity of 3,4-dichloromaleimides: structure-activity relationships.
|
Pharmazie
|
1998
|
0.75
|