I T Huhtaniemi

Author PubWeight™ 65.23‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Mutations of gonadotropins and gonadotropin receptors: elucidating the physiology and pathophysiology of pituitary-gonadal function. Endocr Rev 2000 2.63
2 Late-onset hypogonadism and mortality in aging men. J Clin Endocrinol Metab 2013 1.77
3 Preputial separation as an external sign of pubertal development in the male rat. Biol Reprod 1977 1.72
4 Chronic widespread pain is associated with slower cognitive processing speed in middle-aged and older European men. Pain 2010 1.58
5 Expression and regulation of transcription factors GATA-4 and GATA-6 in developing mouse testis. Endocrinology 1999 1.42
6 Men homozygous for an inactivating mutation of the follicle-stimulating hormone (FSH) receptor gene present variable suppression of spermatogenesis and fertility. Nat Genet 1997 1.30
7 Expression and hormonal regulation of transcription factors GATA-4 and GATA-6 in the mouse ovary. Endocrinology 1997 1.25
8 The effects of neurokinin B upon gonadotrophin release in male rodents. J Neuroendocrinol 2009 1.22
9 Age-associated changes in hypothalamic-pituitary-testicular function in middle-aged and older men are modified by weight change and lifestyle factors: longitudinal results from the European Male Ageing Study. Eur J Endocrinol 2013 1.17
10 Gonadal tumorigenesis in transgenic mice bearing the mouse inhibin alpha-subunit promoter/simian virus T-antigen fusion gene: characterization of ovarian tumors and establishment of gonadotropin-responsive granulosa cell lines. Mol Endocrinol 1995 1.08
11 Elevated luteinizing hormone induces expression of its receptor and promotes steroidogenesis in the adrenal cortex. J Clin Invest 2000 1.04
12 Ontogeny of follicle-stimulating hormone receptor gene expression in the rat testis and ovary. Mol Cell Endocrinol 1995 0.98
13 HCG binding and stimulation of testosterone biosynthesis in the human fetal testis. J Clin Endocrinol Metab 1977 0.97
14 Worldwide frequency of a common genetic variant of luteinizing hormone: an international collaborative research. International Collaborative Research Group. Fertil Steril 1997 0.96
15 Influence of age and sex steroids on bone density and geometry in middle-aged and elderly European men. Osteoporos Int 2010 0.94
16 Investigating the determinants of international differences in the prevalence of chronic widespread pain: evidence from the European Male Ageing Study. Ann Rheum Dis 2008 0.93
17 Assessment of mechanisms of thyroid hormone action in mouse Leydig cells: regulation of the steroidogenic acute regulatory protein, steroidogenesis, and luteinizing hormone receptor function. Endocrinology 2001 0.92
18 Attenuated adenosine R-site effect in adipocytes in obesity. Metabolism 1986 0.90
19 A new contributing factor to polycystic ovary syndrome: the genetic variant of luteinizing hormone. J Clin Endocrinol Metab 1999 0.90
20 Ovarian and adrenal steroid production: regulatory role of LH/HCG. Hum Reprod 2002 0.89
21 Development of luteinizing hormone action in the perinatal rat ovary. Biol Reprod 1996 0.88
22 Molecular mechanisms of thyroid hormone-stimulated steroidogenesis in mouse leydig tumor cells. Involvement of the steroidogenic acute regulatory (StAR) protein. J Biol Chem 1999 0.88
23 Reciprocal changes in the expression of transcription factors GATA-4 and GATA-6 accompany adrenocortical tumorigenesis in mice and humans. Mol Med 1999 0.86
24 Functional assessment of the calcium messenger system in cultured mouse Leydig tumor cells: regulation of human chorionic gonadotropin-induced expression of the steroidogenic acute regulatory protein. Endocrinology 1999 0.86
25 Adrenocortical tumorigenesis in transgenic mice: the role of luteinizing hormone receptor and transcription factors GATA-4 and GATA-61. Reprod Biol 2001 0.86
26 Differential binding affinities of rat testis luteinizing hormone (LH) receptors for human chorionic gonadotropin, human LH, and ovine LH. Endocrinology 1981 0.86
27 Luteinizing hormone-receptor interaction in the testis: progressive decrease in reversibility of the hormone-receptor complex. Endocrinology 1980 0.85
28 Inhibin binding sites and proteins in pituitary, gonadal, adrenal and bone cells. Mol Cell Endocrinol 2001 0.84
29 Disparate response of wild-type and variant forms of LH to GnRH stimulation in individuals heterozygous for the LHbeta variant allele. Hum Reprod 2001 0.84
30 Transplantation of newborn rat testis under the kidney capsule of adult host as a model to study the structure and function of Leydig cells. J Androl 1990 0.84
31 Novel epididymal proteins as targets for the development of post-testicular male contraception. Reproduction 2009 0.83
32 Inhibition of adenosine 3',5'-monophosphate accumulation and lipolysis by adenosine analogs in human subcutaneous adipocytes. J Clin Endocrinol Metab 1984 0.83
33 Cloning and functional expression of the luteinizing hormone receptor complementary deoxyribonucleic acid from the marmoset monkey testis: absence of sequences encoding exon 10 in other species. Endocrinology 1997 0.83
34 Regulation and function of the primate fetal adrenal gland and gonad. Recent Prog Horm Res 1981 0.83
35 Content of chorionic gonadotropin in human fetal tissues. J Clin Endocrinol Metab 1978 0.83
36 Absence of gonadotropin-releasing hormone receptors in human gonadal tissue. Nature 1982 0.82
37 Molecular mechanisms of reappearance of luteinizing hormone receptor expression and function in rat testis after selective Leydig cell destruction by ethylene dimethane sulfonate. Endocrinology 1997 0.82
38 Functional maturation of the pituitary-gonadal axis in the neonatal female rat. Biol Reprod 1995 0.82
39 Ontogeny of gonadotropin receptors in the fetal and neonatal rat testis. Endocrinology 1984 0.82
40 Gonadal sex steroid status and bone health in middle-aged and elderly European men. Osteoporos Int 2009 0.81
41 Acquisition of regulatory mechanisms for gonadotropin receptors and steroidogenesis in the maturing rat testis. Endocrinology 1982 0.81
42 Improved technique for detection of enhanced green fluorescent protein in transgenic mice. Biotechniques 2001 0.80
43 Induction and maintenance of gonadotropin and lactogen receptors in hypoprolactinemic rats. Endocrinology 1981 0.80
44 Transgenic mouse models for gonadal tumorigenesis. Mol Cell Endocrinol 1998 0.80
45 Luteinizing hormone, its beta-subunit variant, and epithelial ovarian cancer: the gonadotropin hypothesis revisited. Am J Epidemiol 2001 0.79
46 Thyroid hormones and male sexual function. Int J Androl 2012 0.79
47 Biphasic action of prolactin in the regulation of murine Leydig tumor cell functions. Endocrinology 2001 0.79
48 Gonadotropin-induced positive regulation of testicular luteinizing hormone receptors. Endocrinology 1981 0.79
49 Inactivating FSH receptor mutations and gonadal dysfunction. Mol Cell Endocrinol 1998 0.79
50 Follicle-stimulating hormone ligand and receptor mutations, and gonadal dysfunction. Arch Med Res 2000 0.79
51 Transcriptional and translational regulation of LH, prolactin and their testicular receptors by hCG and bromocriptine treatments in adult and neonatal rats. Mol Cell Endocrinol 1994 0.79
52 Ovarian tumorigenesis in mice transgenic for murine inhibin alpha subunit promoter-driven Simian Virus 40 T-antigen: ontogeny, functional characteristics, and endocrine effects. Biol Reprod 2001 0.79
53 Interaction of thyroid hormone and steroidogenic acute regulatory (StAR) protein in the regulation of murine Leydig cell steroidogenesis. J Steroid Biochem Mol Biol 2001 0.79
54 Frailty Is Associated with Impaired Quality of Life and Falls in Middle-Aged and Older European Men. J Frailty Aging 2013 0.78
55 Effect of postnatal treatment with a gonadotropin-releasing hormone antagonist on sexual maturation of male rats. Biol Reprod 1986 0.78
56 Many LH peaks are needed to physiologically stimulate testosterone secretion: modulation by fasting and NPY. Am J Physiol 1999 0.78
57 Effects of endurance training on hormonal responses to prolonged physical exercise in males. Acta Endocrinol (Copenh) 1993 0.78
58 Regulation of luteinizing-hormone-receptors and steroidogenesis in the neonatal rat testis. Endocrinology 1981 0.77
59 Mechanisms of desensitization of follicle-stimulating hormone (FSH) action in a murine granulosa cell line stably transfected with the human FSH receptor complementary deoxyribonucleic acid. Mol Cell Endocrinol 1998 0.77
60 Pituitary-testicular function in immature rats after treatment with GnRH antagonist, GnRH antiserum and bromocriptine. Mol Cell Endocrinol 1984 0.77
61 Regulation of LH receptors and steroidogenesis in the foetal rat testis in vivo. Acta Endocrinol (Copenh) 1987 0.77
62 New insights into the role of follicle-stimulating hormone in reproduction. Ann Med 1997 0.77
63 Reproductive hormones, cancers, and conditions in relation to a common genetic variant of luteinizing hormone. Hum Reprod 2000 0.77
64 Pituitary-gonadal response to gonadotropin-releasing hormone stimulation is enhanced in men after strenuous physical exercise. Acta Endocrinol (Copenh) 1993 0.76
65 Newborn and immature rat testes contain gonadotropin-releasing hormone (GnRH) receptors, and their testosterone production is stimulated by a GnRH agonist in vitro. Mol Cell Endocrinol 1985 0.76
66 Comparison of oestrogen and GnRH agonist analogue-induced inhibition of the pituitary-testicular function in rat. Acta Endocrinol (Copenh) 1983 0.76
67 Luteinizing hormone and different genetic variants, as indicators of frailty in healthy elderly men. J Clin Endocrinol Metab 1999 0.76
68 Investigating the role of pain-modulating pathway genes in musculoskeletal pain. Eur J Pain 2012 0.76
69 Blockade of rat testicular gonadotropin releasing hormone (GnRH) receptors by infusion of a GnRH antagonist has no major effects of Leydig cell function in vivo. Mol Cell Endocrinol 1987 0.76
70 Epidemiological evidence against a role for C-reactive protein causing leptin resistance. Eur J Endocrinol 2012 0.76
71 Development of gonadal feedback regulation of gonadotropin gene expression and secretion in female rats. Acta Endocrinol (Copenh) 1992 0.76
72 Gonadotropin binding and Leydig cell activation in the rat testis in vivo. Endocrinology 1982 0.76
73 Functional maturation of rat testis Leydig cells. Ann N Y Acad Sci 1984 0.75
74 [Prevalence of genetic variants of luteinizing hormone in the Czech Republic]. Cas Lek Cesk 1999 0.75
75 Carbohydrate ingestion during prolonged running exercise results in an increase of serum cortisol and decrease of gonadotrophins. Acta Physiol Scand 1991 0.75
76 Gonadotropin-releasing hormone agonist analog-induced steroidogenic lesion in the neonatal rat testis: evidence for direct gonadal action. Endocrinology 1984 0.75
77 Persistence of biological activity of biotinylated human chorionic gonadotropin and its use for visualization of rat luteinizing hormone receptors in tissue sections. J Histochem Cytochem 1998 0.75
78 Effects of gonadotropin-releasing hormone receptor blockade on rat testicular gonadotropin and lactogen receptors, steroidogenesis, and responses to human chorionic gonadotropin stimulation. Endocrinology 1985 0.75
79 Stimulation of pituitary-testicular function with gonadotropin-releasing hormone in fetal and infant monkeys. Endocrinology 1979 0.75
80 Gonadotrophin receptors: correlates with normal and pathological functions of the human ovary and testis. Clin Endocrinol Metab 1983 0.75
81 Physiological role of putative testicular gonadotrophin releasing hormone (GnRH). Med Biol 1986 0.75
82 Measurement of plasma free luteinizing hormone beta-subunit in women. J Clin Endocrinol Metab 2000 0.75
83 'Andrology'- the New Journal of the American Society of Andrology and the European Academy of Andrology. Int J Androl 2012 0.75
84 Catabolism of human [125I]iodochorionic gonadotropin in rat testis. Endocrinology 1979 0.75
85 Absence of gonadotropin-induced desensitization of testosterone production in the neonatal rat testis. Mol Cell Endocrinol 1983 0.75
86 Genetic variant of luteinizing hormone: impact on gonadal steroid sex hormones in women. Physiol Res 2001 0.75
87 The effect of ski training at altitude and racing on pituitary, adrenal and testicular function in men. Eur J Appl Physiol Occup Physiol 1993 0.75
88 Kinetic and autoradiographic studies on binding of hCG to the testicular LH receptors of neonatal rats. J Reprod Fertil 1986 0.75
89 Salivary progesterone measurements reveal corpus luteum defects which respond poorly to hormonal treatments in operated mild and moderate endometriosis. Hum Reprod 1991 0.75
90 [Gonadotropin-releasing hormone and its clinical use]. Duodecim 1981 0.75
91 Development of heterologous down-regulation of lactogen receptors in the rat testis. Mol Cell Endocrinol 1983 0.75
92 Gonadal tumors of mice double transgenic for inhibin-alpha promoter-driven simian virus 40 T-antigen and herpes simplex virus thymidine kinase are sensitive to ganciclovir treatment. J Endocrinol 2001 0.75
93 Ontogeny of gonadotropin action in the rat ovary. J Physiol Pharmacol 1992 0.75
94 Gonadotrophin-releasing hormone and human chorionic gonadotrophin tests reveal that both hypothalamic and testicular endocrine functions are suppressed during acute prolonged physical exercise. Clin Endocrinol (Oxf) 1990 0.75
95 Genetic variant of luteinizing hormone in Czech Republic. Endocr Regul 1999 0.75
96 Effect of treatment with GnRH antagonist, GnRH antiserum and bromocriptine on pituitary-testicular function of adult rats. Mol Cell Endocrinol 1984 0.75
97 The FSH beta-subunit promoter directs the expression of Herpes simplex virus type 1 thymidine kinase to the testis of transgenic mice. Mol Cell Endocrinol 1993 0.75
98 Evaluation of the 5'-flanking regions of murine glutathione peroxidase five and cysteine-rich secretory protein-1 genes for directing transgene expression in mouse epididymis. Biol Reprod 2001 0.75
99 Regulation of infant and developing rat testicular gonadotropin and prolactin receptors and steroidogenesis by treatments with human chorionic gonadotropin, gonadotropin-releasing hormone analogs, bromocriptine, prolactin, and estrogen. Biol Reprod 1985 0.75