The Losartan Intervention For Endpoint reduction (LIFE) in Hypertension study: rationale, design, and methods. The LIFE Study Group.

PubWeight™: 1.28‹?› | Rank: Top 10%

🔗 View Article (PMID 9234823)

Published in Am J Hypertens on July 01, 1997

Authors

B Dahlöf1, R Devereux, U de Faire, F Fyhrquist, T Hedner, H Ibsen, S Julius, S Kjeldsen, K Kristianson, O Lederballe-Pedersen, L H Lindholm, M S Nieminen, P Omvik, S Oparil, H Wedel

Author Affiliations

1: Ostra University Hospital, Göteborg, Sweden.

Articles citing this

Angiotensin-receptor blockade and risk of cancer: meta-analysis of randomised controlled trials. Lancet Oncol (2010) 9.28

Race and ethnicity in trials of antihypertensive therapy to prevent cardiovascular outcomes: a systematic review. Ann Fam Med (2007) 1.54

Underdiagnosis of hypertension using electronic health records. Am J Hypertens (2011) 1.04

Determinants of discrepancies in detection and comparison of the prognostic significance of left ventricular hypertrophy by electrocardiogram and cardiac magnetic resonance imaging. Am J Cardiol (2014) 0.96

Metabolic syndrome and left ventricular hypertrophy in the prediction of cardiovascular events: the Strong Heart Study. Nutr Metab Cardiovasc Dis (2008) 0.91

Marked regional left ventricular heterogeneity in hypertensive left ventricular hypertrophy patients: a losartan intervention for endpoint reduction in hypertension (LIFE) cardiovascular magnetic resonance and echocardiographic substudy. Hypertension (2008) 0.89

Enhanced angiotensin II-mediated central sympathoexcitation in streptozotocin-induced diabetes: role of superoxide anion. Am J Physiol Regul Integr Comp Physiol (2010) 0.87

Current cardiac imaging techniques for detection of left ventricular mass. Cardiovasc Ultrasound (2010) 0.82

Flow propagation velocity is not a simple index of diastolic function in early filling. A comparative study of early diastolic strain rate and strain rate propagation, flow and flow propagation in normal and reduced diastolic function. Cardiovasc Ultrasound (2003) 0.80

Increasing complexity: which drug class to choose for treatment of hypertension in the elderly? Clin Interv Aging (2014) 0.79

Left Ventricular Hypertrophy. Curr Treat Options Cardiovasc Med (1999) 0.78

Left ventricular geometric patterns and adaptations to hemodynamics are similar in elderly men and women. BMC Cardiovasc Disord (2011) 0.77

Fixed combination of losartan and hydrochlorothiazide and reduction of risk of stroke. Vasc Health Risk Manag (2007) 0.77

Regional Heterogeneity in 3D Myocardial Shortening in Hypertensive Left Ventricular Hypertrophy: A Cardiovascular CMR Tagging Substudy to the Life Study. J Biomed Sci Eng (2015) 0.75

Pharmacological Modulation of Calcium Homeostasis in Familial Dilated Cardiomyopathy: An In Vitro Analysis From an RBM20 Patient-Derived iPSC Model. Clin Transl Sci (2016) 0.75

Marketing trials, marketing tricks - how to spot them and how to stop them. Trials (2017) 0.75

Systematic review: antihypertensive drug therapy in patients of African and South Asian ethnicity. Intern Emerg Med (2016) 0.75

Articles by these authors

Combination of 16S rRNA-targeted oligonucleotide probes with flow cytometry for analyzing mixed microbial populations. Appl Environ Microbiol (1990) 34.40

Effects of intensive blood-pressure lowering and low-dose aspirin in patients with hypertension: principal results of the Hypertension Optimal Treatment (HOT) randomised trial. HOT Study Group. Lancet (1998) 26.64

Recommendations for quantitation of the left ventricle by two-dimensional echocardiography. American Society of Echocardiography Committee on Standards, Subcommittee on Quantitation of Two-Dimensional Echocardiograms. J Am Soc Echocardiogr (1990) 25.24

Estimation of ten-year risk of fatal cardiovascular disease in Europe: the SCORE project. Eur Heart J (2003) 17.80

Meta-analysis of how well measures of bone mineral density predict occurrence of osteoporotic fractures. BMJ (1996) 11.60

Molecular and microscopic identification of sulfate-reducing bacteria in multispecies biofilms. Appl Environ Microbiol (1992) 10.81

Morbidity and mortality in the Swedish Trial in Old Patients with Hypertension (STOP-Hypertension) Lancet (1991) 9.57

Randomised trial of old and new antihypertensive drugs in elderly patients: cardiovascular mortality and morbidity the Swedish Trial in Old Patients with Hypertension-2 study. Lancet (1999) 7.65

Effect of nesiritide in patients with acute decompensated heart failure. N Engl J Med (2011) 7.62

Serological evidence of an association of a novel Chlamydia, TWAR, with chronic coronary heart disease and acute myocardial infarction. Lancet (1988) 7.59

Effect of angiotensin-converting-enzyme inhibition compared with conventional therapy on cardiovascular morbidity and mortality in hypertension: the Captopril Prevention Project (CAPPP) randomised trial. Lancet (1999) 7.56

Genetic susceptibility to death from coronary heart disease in a study of twins. N Engl J Med (1994) 7.47

Effects of controlled-release metoprolol on total mortality, hospitalizations, and well-being in patients with heart failure: the Metoprolol CR/XL Randomized Intervention Trial in congestive heart failure (MERIT-HF). MERIT-HF Study Group. JAMA (2000) 5.49

Intense metabolic control by means of insulin in patients with diabetes mellitus and acute myocardial infarction (DIGAMI 2): effects on mortality and morbidity. Eur Heart J (2005) 5.40

Effect on mortality of metoprolol in acute myocardial infarction. A double-blind randomised trial. Lancet (1981) 4.75

Rationale and design for the Antihypertensive and Lipid Lowering Treatment to Prevent Heart Attack Trial (ALLHAT). ALLHAT Research Group. Am J Hypertens (1996) 4.66

Randomized trial of insulin-glucose infusion followed by subcutaneous insulin treatment in diabetic patients with acute myocardial infarction (DIGAMI study): effects on mortality at 1 year. J Am Coll Cardiol (1995) 4.50

Randomised trial of effects of calcium antagonists compared with diuretics and beta-blockers on cardiovascular morbidity and mortality in hypertension: the Nordic Diltiazem (NORDIL) study. Lancet (2000) 4.09

Association between dental health and acute myocardial infarction. BMJ (1989) 3.94

Effects of the early administration of enalapril on mortality in patients with acute myocardial infarction. Results of the Cooperative New Scandinavian Enalapril Survival Study II (CONSENSUS II) N Engl J Med (1992) 3.87

Coronary heart-disease after treatment of hypertension. Lancet (1978) 3.78

Essential hypertension. Part I: definition and etiology. Circulation (2000) 3.59

Genetic and environmental influences on serum lipid levels in twins. N Engl J Med (1993) 3.43

Glycometabolic state at admission: important risk marker of mortality in conventionally treated patients with diabetes mellitus and acute myocardial infarction: long-term results from the Diabetes and Insulin-Glucose Infusion in Acute Myocardial Infarction (DIGAMI) study. Circulation (1999) 3.20

Multivariate analysis of risk factors for coronary heart disease. Circulation (1973) 3.04

Risk factors for cardiovascular disease in systemic lupus erythematosus. Circulation (2001) 2.72

Comparison of Escherichia coli from bacteriuric patients with those from feces of healthy schoolchildren. J Infect Dis (1977) 2.72

Chlamydia pneumoniae-specific circulating immune complexes in patients with chronic coronary heart disease. Circulation (1993) 2.70

Beta-blockers versus diuretics in hypertensive men: main results from the HAPPHY trial. J Hypertens (1987) 2.59

Changes in glomerular filtration rate during long-term treatment with propranolol in patients with arterial hypertension. Clin Sci (1973) 2.52

Prospective randomized open blinded end-point (PROBE) study. A novel design for intervention trials. Prospective Randomized Open Blinded End-Point. Blood Press (1992) 2.49

Smokeless tobacco use and increased cardiovascular mortality among Swedish construction workers. Am J Public Health (1994) 2.41

Lipoprotein changes and reduction in the incidence of major coronary heart disease events in the Scandinavian Simvastatin Survival Study (4S) Circulation (1998) 2.40

Increased plasma levels of a rapid inhibitor of tissue plasminogen activator in young survivors of myocardial infarction. N Engl J Med (1985) 2.39

Reduced cardiovascular morbidity and mortality in hypertensive diabetic patients on first-line therapy with an ACE inhibitor compared with a diuretic/beta-blocker-based treatment regimen: a subanalysis of the Captopril Prevention Project. Diabetes Care (2001) 2.39

Antibodies to cardiolipin in young survivors of myocardial infarction: an association with recurrent cardiovascular events. Lancet (1986) 2.38

Erythropoietin, aluminium, and anaemia in patients on haemodialysis. Lancet (1990) 2.35

Cost-effectiveness of cholesterol lowering. Results from the Scandinavian Simvastatin Survival Study (4S) Eur Heart J (1996) 2.31

Genomic complexity and plasticity of Burkholderia cepacia. FEMS Microbiol Lett (1996) 2.24

Plasma tumour necrosis factor-alpha and early carotid atherosclerosis in healthy middle-aged men. Eur Heart J (2002) 2.24

Cholesterol lowering and the use of healthcare resources. Results of the Scandinavian Simvastatin Survival Study. Circulation (1996) 2.23

Plasminogen activator inhibitor in plasma: risk factor for recurrent myocardial infarction. Lancet (1987) 2.23

Blood pressure crisis following withdrawal of clonidine (Catapres, Catapresan), with special reference to arterial and urinary catecholamine levels, and suggestions for acute management. Am Heart J (1973) 2.17

Body weight and weight gain during adult life in men in relation to coronary heart disease and mortality. A prospective population study. Eur Heart J (1999) 2.16

Home blood pressure determination. Value in borderline ("labile") hypertension. JAMA (1974) 2.16

Comparative effects of ramipril on ambulatory and office blood pressures: a HOPE Substudy. Hypertension (2001) 2.15

Plasma atrial natriuretic peptide in cardiac disease and during infusion in healthy volunteers. Lancet (1985) 2.12

Reduction in incidence of diabetes, hypertension and lipid disturbances after intentional weight loss induced by bariatric surgery: the SOS Intervention Study. Obes Res (1999) 2.11

Cardiomyocyte apoptosis and progression of heart failure to transplantation. Eur J Clin Invest (1999) 2.06

Accuracy of bedside diagnosis in stroke. Stroke (1981) 2.06

The 1993 guidelines for the management of mild hypertension: memorandum from a WHO/ISH meeting. Blood Press (1993) 2.03

Reference values for self-recorded blood pressure: a meta-analysis of summary data. Arch Intern Med (1998) 2.01

Renal function and intensive lowering of blood pressure in hypertensive participants of the hypertension optimal treatment (HOT) study. J Am Soc Nephrol (2001) 1.94

Practice guidelines for primary care physicians: 2003 ESH/ESC hypertension guidelines. J Hypertens (2003) 1.93

Cessation of smoking after myocardial infarction. Effects on mortality after 10 years. Br Heart J (1983) 1.90

Morphine-3-glucuronide may functionally antagonize morphine-6-glucuronide induced antinociception and ventilatory depression in the rat. Pain (1992) 1.89

Prevention of the angiographic progression of coronary and vein-graft atherosclerosis by gemfibrozil after coronary bypass surgery in men with low levels of HDL cholesterol. Lopid Coronary Angiography Trial (LOCAT) Study Group. Circulation (1997) 1.89

The multifactor primary prevention trial in Göteborg, Sweden. Eur Heart J (1986) 1.85

Direct in vivo evidence demonstrating neointimal migration of adventitial fibroblasts after balloon injury of rat carotid arteries. Circulation (2000) 1.84

Dietary changes favorably affect bone remodeling in older adults. J Am Diet Assoc (1999) 1.84

Safety and efficacy of a novel calcium sensitizer, levosimendan, in patients with left ventricular failure due to an acute myocardial infarction. A randomized, placebo-controlled, double-blind study (RUSSLAN). Eur Heart J (2002) 1.83

Effects of insulin treatment on cause-specific one-year mortality and morbidity in diabetic patients with acute myocardial infarction. DIGAMI Study Group. Diabetes Insulin-Glucose in Acute Myocardial Infarction. Eur Heart J (1996) 1.83

Effects of increased consumption of fluid milk on energy and nutrient intake, body weight, and cardiovascular risk factors in healthy older adults. J Am Diet Assoc (2000) 1.82

A comparison between participants and non-participants in a primary preventive trial. J Chronic Dis (1976) 1.80

Cost effectiveness of simvastatin treatment to lower cholesterol levels in patients with coronary heart disease. Scandinavian Simvastatin Survival Study Group. N Engl J Med (1997) 1.79

Felodipine--a new vasodilator, in addition to beta-receptor blockade in hypertension. Eur J Clin Pharmacol (1983) 1.77

Seasonal changes in the relative abundance of uncultivated sulfate-reducing bacteria in a salt marsh sediment and in the rhizosphere of Spartina alterniflora. Appl Environ Microbiol (1997) 1.76

Psychosocial factors and venous thromboembolism: a long-term follow-up study of Swedish men. J Thromb Haemost (2007) 1.74

Home blood pressure monitoring. Arch Intern Med (2000) 1.71

Compartmentalization of angiotensin II generation in the dog heart. Evidence for independent mechanisms in intravascular and interstitial spaces. J Clin Invest (1997) 1.71

Heart rate variability and progression of coronary atherosclerosis. Arterioscler Thromb Vasc Biol (1999) 1.70

Prognostic value of angiographic indices of coronary artery disease from the Coronary Artery Surgery Study (CASS). J Clin Invest (1983) 1.70

Safety and tolerability of cholesterol lowering with simvastatin during 5 years in the Scandinavian Simvastatin Survival Study. Arch Intern Med (1996) 1.68

Decreases by magnesium of QT dispersion and ventricular arrhythmias in patients with acute myocardial infarction. Eur Heart J (1999) 1.67

Stable carbon isotope analysis of nucleic acids to trace sources of dissolved substrates used by estuarine bacteria. Appl Environ Microbiol (1990) 1.67

The reaction of salivary substances with bacteria. J Oral Pathol (1975) 1.66

Is abdominal body fat distribution a major explanation for the sex difference in the incidence of myocardial infarction? The study of men born in 1913 and the study of women, Göteborg, Sweden. Am J Epidemiol (1992) 1.66

Exercise hemodynamics and myocardial metabolism during long-term beta-adrenergic blockade in severe heart failure. J Am Coll Cardiol (1991) 1.66

Stressful life events, social support, and mortality in men born in 1933. BMJ (1993) 1.66

A validation of cause-of-death certification in 1,156 deaths. Acta Med Scand (1976) 1.65

Oxidative stress, human genetic variation, and disease. Arch Biochem Biophys (2001) 1.65

Spironolactone reduces severity of obstructive sleep apnoea in patients with resistant hypertension: a preliminary report. J Hum Hypertens (2009) 1.64

Survival in treated hypertension: follow up study after two decades. BMJ (1998) 1.64

Diet and exercise are equally effective in reducing risk for cardiovascular disease. Results of a randomized controlled study in men with slightly to moderately raised cardiovascular risk factors. Atherosclerosis (1993) 1.63

Treatment of hypertensive crisis. N Engl J Med (1990) 1.63

[There is no reason to avoid calcium antagonists in hypertension]. Lakartidningen (1996) 1.62

High heart rate: a risk factor for cardiovascular death in elderly men. Arch Intern Med (1999) 1.62

Coronary heart disease, cancer and mortality in male middle-aged light smokers. J Intern Med (1992) 1.62

Radioimmunoassay of plasma renin activity. Clin Chem (1976) 1.62

Trends in the incidence of chronic Philadelphia chromosome negative (Ph-) myeloproliferative disorders in the city of Göteborg, Sweden, during 1983-99. J Intern Med (2004) 1.62

Low-dose metoprolol CR/XL and fluvastatin slow progression of carotid intima-media thickness: Main results from the Beta-Blocker Cholesterol-Lowering Asymptomatic Plaque Study (BCAPS). Circulation (2001) 1.62

Phylogenetic and physiological comparisons of PAH-degrading bacteria from geographically diverse soils. Antonie Van Leeuwenhoek (1997) 1.60

A randomized trial of improved weight loss with a prepared meal plan in overweight and obese patients: impact on cardiovascular risk reduction. Arch Intern Med (2000) 1.58