PubRank

D O Calligaro

Author PubWeight™ 30.22‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Radioreceptor binding profile of the atypical antipsychotic olanzapine. Neuropsychopharmacology 1996 2.18
2 Xanomeline: a novel muscarinic receptor agonist with functional selectivity for M1 receptors. J Pharmacol Exp Ther 1994 1.09
3 Characterization of LY344864 as a pharmacological tool to study 5-HT1F receptors: binding affinities, brain penetration and activity in the neurogenic dural inflammation model of migraine. Life Sci 1997 1.00
4 Olanzapine: a basic science update. Br J Psychiatry Suppl 1999 0.98
5 In vitro and in vivo biochemistry of olanzapine: a novel, atypical antipsychotic drug. J Clin Psychiatry 1997 0.97
6 Muscarinic receptor agonists decrease cocaine self-administration rates in drug-naive mice. Eur J Pharmacol 2000 0.95
7 Xanomeline compared to other muscarinic agents on stimulation of phosphoinositide hydrolysis in vivo and other cholinomimetic effects. Brain Res 1998 0.94
8 Antagonism by olanzapine of dopamine D1, serotonin2, muscarinic, histamine H1 and alpha 1-adrenergic receptors in vitro. Schizophr Res 1999 0.94
9 Arachidonic acid release in cell lines transfected with muscarinic receptors: a simple functional assay to determine response of agonists. Cell Signal 1999 0.89
10 Unexpected antipsychotic-like activity with the muscarinic receptor ligand (5R,6R)6-(3-propylthio-1,2,5-thiadiazol-4-yl)-1-azabicyclo[3.2.1]octane . Eur J Pharmacol 1998 0.88
11 1,2,5-Thiadiazole analogues of aceclidine as potent m1 muscarinic agonists. J Med Chem 1998 0.87
12 Muscarinic receptor agonists, like dopamine receptor antagonist antipsychotics, inhibit conditioned avoidance response in rats. J Pharmacol Exp Ther 1999 0.86
13 The muscarinic receptor agonist BuTAC, a novel potential antipsychotic, does not impair learning and memory in mouse passive avoidance. Schizophr Res 2001 0.86
14 Butylthio[2.2.2] (NNC 11-1053/LY297802): an orally active muscarinic agonist analgesic. J Pharmacol Exp Ther 1997 0.85
15 Potential role of muscarinic receptors in schizophrenia. Life Sci 1999 0.85
16 1-(1,2,5-Thiadiazol-4-yl)-4-azatricyclo[2.2.1.0(2,6)]heptanes as new potent muscarinic M1 agonists: structure-activity relationship for 3-aryl-2-propyn-1-yloxy and 3-aryl-2-propyn-1-ylthio derivatives. J Med Chem 1999 0.85
17 Preclinical studies on LY237733, a potent and selective serotonergic antagonist. J Pharmacol Exp Ther 1992 0.84
18 DL-tetrazol-5-ylglycine, a highly potent NMDA agonist: its synthesis and NMDA receptor efficacy. J Med Chem 1992 0.84
19 In vivo pharmacology of butylthio[2.2.2] (LY297802 / NNC11-1053), an orally acting antinociceptive muscarinic agonist. Life Sci 1997 0.84
20 5,7-Dichlorokynurenic acid, a potent and selective competitive antagonist of the glycine site on NMDA receptors. Neurosci Lett 1990 0.83
21 The novel 5-Hydroxytryptamine(1A) antagonist LY426965: effects on nicotine withdrawal and interactions with fluoxetine. J Pharmacol Exp Ther 2000 0.83
22 Functionally selective M1 muscarinic agonists. 3. Side chains and azacycles contributing to functional muscarinic selectivity among pyrazinylazacycles. J Med Chem 1995 0.82
23 Muscarinic agonists with antipsychotic-like activity: structure-activity relationships of 1,2,5-thiadiazole analogues with functional dopamine antagonist activity. J Med Chem 1998 0.81
24 Synthesis and excitatory amino acid pharmacology of a series of heterocyclic-fused quinoxalinones and quinazolinones. J Med Chem 1992 0.81
25 Neurochemical effects of the M1 muscarinic agonist xanomeline (LY246708/NNC11-0232). J Pharmacol Exp Ther 1994 0.79
26 Muscarinic analgesics with potent and selective effects on the gastrointestinal tract: potential application for the treatment of irritable bowel syndrome. J Med Chem 1997 0.79
27 High affinity binding of [3H] cocaine to rat liver microsomes. Life Sci 1988 0.78
28 A current review of olanzapine's safety in the geriatric patient: from pre-clinical pharmacology to clinical data. Int J Geriatr Psychiatry 2001 0.78
29 N-[3-(2-Dimethylaminoethyl)-2-methyl-1H- indol-5-yl]-4-fluorobenzamide: a potent, selective, and orally active 5-HT(1F) receptor agonist potentially useful for migraine therapy. J Med Chem 2001 0.78
30 Preclinical studies on LY228729: a potent and selective serotonin1A agonist. J Pharmacol Exp Ther 1993 0.77
31 Pharmacology of butylthio[2.2.2] (LY297802/NNC11-1053): a novel analgesic with mixed muscarinic receptor agonist and antagonist activity. J Pharmacol Exp Ther 1997 0.76
32 Conformationally constrained analogues of the muscarinic agonist 3-(4-(methylthio)-1,2,5-thiadiazol-3-yl)-1,2,5,6-tetrahydro-1-methylpyr idine. Synthesis, receptor affinity, and antinociceptive activity. J Med Chem 1998 0.76
33 Receptor reserve of phosphoinositide-coupled muscarinic receptors in mouse hippocampus in vivo. Brain Res 2001 0.76
34 Muscarinic agonists exhibit functional dopamine antagonism in unilaterally 6-OHDA lesioned rats. Neuroreport 1998 0.76
35 Allosteric regulation by sodium of the binding of [3H]cocaine and [3H]GBR 12935 to rat and bovine striata. Membr Biochem 1993 0.75
36 Synthesis and structure-activity relationships of potent and orally active 5-HT4 receptor antagonists: indazole and benzimidazolone derivatives. J Med Chem 1998 0.75
37 3-Phenyl-4-hydroxyquinolin-2(1H)-ones: potent and selective antagonists at the strychnine-insensitive glycine site on the N-methyl-D-aspartate receptor complex. J Med Chem 1992 0.75
38 Comparative 5-HT2-receptor antagonist activity of amesergide and its active metabolite 4-hydroxyamesergide in rats and rabbits. J Pharm Pharmacol 1994 0.75
39 Direct pharmacological comparison of the muscarinic receptors mediating relaxation and contraction in the rabbit thoracic aorta. Gen Pharmacol 1999 0.75
40 Pharmacological characterization of LY293284: A 5-HT1A receptor agonist with high potency and selectivity. J Pharmacol Exp Ther 1994 0.75
41 Muscarinic agonists as analgesics. Antinociceptive activity versus M1 activity: SAR of alkylthio-TZTP's and related 1,2,5-thiadiazole analogs. Life Sci 1995 0.75
42 General pharmacology of a new potent 5-hydroxytryptamine antagonist. Arzneimittelforschung 1991 0.75
43 Identification of side chains on 1,2,5-thiadiazole-azacycles optimal for muscarinic m1 receptor activation. Bioorg Med Chem Lett 1998 0.75