P Schirmacher

Author PubWeight™ 119.07‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Expression of an ASCL2 related stem cell signature and IGF2 in colorectal cancer liver metastases with 11p15.5 gain. Gut 2010 3.24
2 Dysregulation of growth factor signaling in human hepatocellular carcinoma. Oncogene 2006 2.49
3 Molecular characterisation of pancreatic ductal adenocarcinoma in patients under 40. J Clin Pathol 2006 2.33
4 Perforation of the esophagus after dilation treatment for dysphagia in a patient with eosinophilic esophagitis. Endoscopy 2006 2.24
5 Assembly of the major and the minor capsid protein of human papillomavirus type 33 into virus-like particles and tubular structures in insect cells. Virology 1994 1.89
6 Detection of hepatitis C virus in paraffin-embedded liver biopsies of patients negative for viral RNA in serum. Hepatology 1999 1.79
7 [Prophylaxis, diagnosis and therapy of hepatitis C virus (HCV) infection: the German guidelines on the management of HCV infection]. Z Gastroenterol 2010 1.76
8 Binding and internalization of human papillomavirus type 33 virus-like particles by eukaryotic cells. J Virol 1995 1.70
9 TGF-beta1 in liver fibrosis: an inducible transgenic mouse model to study liver fibrogenesis. Am J Physiol 1999 1.69
10 Chromosome alterations in human hepatocellular carcinomas correlate with aetiology and histological grade--results of an explorative CGH meta-analysis. Br J Cancer 2005 1.64
11 Proinflammatory cytokines cause FAT10 upregulation in cancers of liver and colon. Oncogene 2008 1.59
12 VHL alterations in human clear cell renal cell carcinoma: association with advanced tumor stage and a novel hot spot mutation. Cancer Res 2000 1.58
13 Mediastinal angiomyolipomas in a male patient affected by tuberous sclerosis. Eur Respir J 2008 1.55
14 Expression of a dominant negative type II TGF-beta receptor in mouse skin results in an increase in carcinoma incidence and an acceleration of carcinoma development. Oncogene 1998 1.43
15 [Participation and support of clinical studies and other scientific investigations. Statement of the German Society for Pathology]. Pathologe 2013 1.42
16 Tenascin C and annexin II expression in the process of pancreatic carcinogenesis. J Pathol 2006 1.41
17 [Remove polyps and discard. Way or wrong way?]. Pathologe 2015 1.39
18 Woodchuck hepatitis virus X protein is present in chronically infected woodchuck liver and woodchuck hepatocellular carcinomas which are permissive for viral replication. J Virol 1996 1.35
19 Hepatocellular expression of a dominant-negative mutant TGF-beta type II receptor accelerates chemically induced hepatocarcinogenesis. Oncogene 2001 1.33
20 [Prophylaxis, diagnosis and therapy of hepatitis B virus infection - the German guideline]. Z Gastroenterol 2011 1.24
21 Minilaparoscopy in the diagnosis of cirrhosis: superiority in patients with Child-Pugh A and macronodular disease. Endoscopy 2003 1.24
22 Prediction of progressive liver fibrosis in hepatitis C infection by serum and tissue levels of transforming growth factor-beta. J Viral Hepat 2001 1.23
23 Expression and functional interaction of hepatocyte growth factor-scatter factor and its receptor c-met in mammalian brain. J Cell Biol 1994 1.21
24 Keratinocyte-derived granulocyte-macrophage colony stimulating factor accelerates wound healing: Stimulation of keratinocyte proliferation, granulation tissue formation, and vascularization. J Invest Dermatol 2001 1.17
25 Increased expression of ALCAM/CD166 in pancreatic cancer is an independent prognostic marker for poor survival and early tumour relapse. Br J Cancer 2009 1.16
26 Overexpression of bone morphogenetic protein-6 (BMP-6) in the epidermis of transgenic mice: inhibition or stimulation of proliferation depending on the pattern of transgene expression and formation of psoriatic lesions. J Cell Biol 1996 1.13
27 Extramedullary expansion of hematopoietic progenitor cells in interleukin (IL)-6-sIL-6R double transgenic mice. J Exp Med 1997 1.13
28 Methotrexate specifically modulates cytokine production by T cells and macrophages in murine collagen-induced arthritis (CIA): a mechanism for methotrexate-mediated immunosuppression. Clin Exp Immunol 1999 1.13
29 Hepatocyte growth factor-stimulated invasiveness of monocytes. Blood 2000 1.08
30 Helicobacter pylori genotyping in gastric adenocarcinoma and MALT lymphoma by multiplex PCR analyses of paraffin wax embedded tissues. Mol Pathol 2003 1.07
31 Disrupted IGF2 promoter control by silencing of promoter P1 in human hepatocellular carcinoma. Cancer Res 1997 1.05
32 Neoexpression of the c-met/hepatocyte growth factor-scatter factor receptor gene in activated monocytes. Blood 1997 1.04
33 c-myc amplifications in primary breast carcinomas and their local recurrences. J Clin Pathol 2006 1.04
34 Heterozygosity for the hemochromatosis gene in liver diseases--prevalence and effects on liver histology. Liver 2000 0.99
35 Combined interleukin 6 and soluble interleukin 6 receptor accelerates murine liver regeneration. Gastroenterology 2000 0.99
36 Hepatoma-derived integrated HBV DNA causes multi-stage transformation in vitro. Oncogene 1996 0.99
37 Expression of mutated hepatitis B virus X genes in human hepatocellular carcinomas. Int J Cancer 1999 0.99
38 Functional characterisation of decoy receptor 3 in Crohn's disease. Gut 2008 0.98
39 Expression and localization of scatter factor/hepatocyte growth factor in human astrocytomas. Neuro Oncol 2001 0.97
40 Chemoradiation in patients with unresectable extrahepatic and hilar cholangiocarcinoma or at high risk for disease recurrence after resection : Analysis of treatment efficacy and failure in patients receiving postoperative or primary chemoradiation. Strahlenther Onkol 2012 0.96
41 Frequent genomic imbalances suggest commonly altered tumour genes in human hepatocarcinogenesis. Br J Cancer 2001 0.96
42 Real-time tissue elastography versus FibroScan for noninvasive assessment of liver fibrosis in chronic liver disease. Ultraschall Med 2009 0.94
43 Bile duct epithelia as target cells in primary biliary cirrhosis and primary sclerosing cholangitis. Virchows Arch 1997 0.94
44 Intensity modulated radiotherapy as neoadjuvant chemoradiation for the treatment of patients with locally advanced pancreatic cancer. Outcome analysis and comparison with a 3D-treated patient cohort. Strahlenther Onkol 2013 0.94
45 Fut2 genotype is a risk factor for dominant stenosis and biliary candida infections in primary sclerosing cholangitis. Aliment Pharmacol Ther 2014 0.93
46 Podocalyxin-like protein 1 expression in primary hepatic tumours and tumour-like lesions. Histopathology 2006 0.93
47 Sequential control of hepatitis B virus in a mouse model of acute, self-resolving hepatitis B. J Viral Hepat 2011 0.93
48 Detection of the ASPSCR1-TFE3 gene fusion in paraffin-embedded alveolar soft part sarcomas. Histopathology 2007 0.93
49 Overexpression of bone morphogenetic protein-6 (BMP-6) in murine epidermis suppresses skin tumor formation by induction of apoptosis and downregulation of fos/jun family members. Oncogene 2001 0.92
50 New concepts on the histogenesis of eccrine neoplasia from keratin expression in the normal eccrine gland, syringoma and poroma. Br J Dermatol 2008 0.92
51 [Diagnosis of and therapy for hepatocellular carcinoma]. Z Gastroenterol 2013 0.91
52 Induction of bone morphogenetic protein-6 in skin wounds. Delayed reepitheliazation and scar formation in BMP-6 overexpressing transgenic mice. J Invest Dermatol 1998 0.91
53 [Histopathological diagnosis of non-alcoholic and alcoholic fatty liver disease. Grade 2 consensus-based guidelines]. Pathologe 2010 0.90
54 Soluble IL-6 receptor leads to a paracrine modulation of the IL-6-induced hepatic acute phase response in double transgenic mice. J Immunol 1997 0.90
55 Prognostic impact of tumour-infiltrating immune cells on biliary tract cancer. Br J Cancer 2013 0.90
56 Prophylaxis, diagnosis and therapy of hepatitis B virus (HBV) infection: the German guidelines for the management of HBV infection. Z Gastroenterol 2007 0.89
57 Interstitial fibrosis in the heart: differences in extracellular matrix proteins and matrix metalloproteinases in end-stage dilated, ischaemic and valvular cardiomyopathy. Histopathology 2006 0.89
58 Inverse regulation of vascular endothelial growth factor and VHL tumor suppressor gene in sporadic renal cell carcinomas is correlated with vascular growth: an in vivo study on 29 tumors. J Mol Med (Berl) 1999 0.88
59 Molecular characterisation of non-absorptive and absorptive enterocytes in human small intestine. Gut 2006 0.88
60 Viral and host factors in the prediction of response to interferon-alpha therapy in chronic hepatitis C after long-term follow-up. J Viral Hepat 1998 0.88
61 The designer cytokine hyper-IL-6 mediates growth inhibition and GM-CSF-dependent rejection of B16 melanoma cells. Oncogene 2001 0.87
62 Oval cell lines OC/CDE 6 and OC/CDE 22 give rise to cholangio-cellular and undifferentiated carcinomas after transformation. Lab Invest 1994 0.87
63 [Enteroparesis caused by progressive fibrosis of the muscularis propria]. Z Gastroenterol 1998 0.86
64 Glycated and carbamylated albumin are more "nephrotoxic" than unmodified albumin in the amphibian kidney. Am J Physiol Renal Physiol 2011 0.86
65 [Virtual microscopy in pathology teaching and postgraduate training (continuing education)]. Pathologe 2008 0.86
66 Progressive focal nodular hyperplasia of the liver in a patient with genetic hemochromatosis--growth promotion by iron overload? Dig Dis Sci 2000 0.85
67 Interleukin-6 and the soluble interleukin-6 receptor induce stem cell factor and Flt-3L expression in vivo and in vitro. Exp Hematol 2001 0.84
68 Expression of c-Met in developing rat hippocampus: evidence for HGF as a neurotrophic factor for calbindin D-expressing neurons. Eur J Neurosci 2000 0.84
69 [Tissue bank of the National Centre for Tumour Disease. An innovative platform for translational tumour]. Pathologe 2008 0.84
70 Epidermal overexpression of granulocyte-macrophage colony-stimulating factor induces both keratinocyte proliferation and apoptosis. Cell Growth Differ 2000 0.83
71 Pathological aspects of cholangiocarcinoma. HPB (Oxford) 2008 0.83
72 Invasion front-specific overexpression of tissue inhibitor of metalloproteinase-1 in liver metastases from colorectal cancer. Anticancer Res 2008 0.83
73 A novel rat model of chronic fibrosing cholangitis induced by local administration of a hapten reagent into the dilated bile duct is associated with increased TNF-alpha production and autoantibodies. J Hepatol 2000 0.83
74 [Clonal association of flat epithelial atypia and tubular breast cancer]. Pathologe 2008 0.82
75 Liver-specific expression of interferon gamma following adenoviral gene transfer controls hepatitis B virus replication in mice. Gene Ther 2005 0.82
76 Up- and down-regulation of granulocyte/macrophage-colony stimulating factor activity in murine skin increase susceptibility to skin carcinogenesis by independent mechanisms. Cancer Res 2001 0.82
77 Combined therapy with azathioprine, prednisolone, and ursodiol in patients with primary sclerosing cholangitis. A case series. Ann Intern Med 1999 0.82
78 Concentrations of hepatocyte growth factor in cerebrospinal fluid under normal and different pathological conditions. Cytokine 2001 0.82
79 [The anti-diabetic drug troglitazone sensitizes colon cancer cells to TRAIL-induced apoptosis by down-regulating FLIP]. Verh Dtsch Ges Pathol 2007 0.82
80 [Histopathological diagnosis and differential diagnosis of colorectal serrated polys: findings of a consensus conference of the working group "gastroenterological pathology of the German Society of Pathology"]. Pathologe 2011 0.82
81 [Villous adenoma within an urachal diverticulum associated with long-term mucusuria]. Pathologe 2008 0.81
82 Coeliac disease is associated with impaired expression of acyl-CoA-synthetase 5. Int J Colorectal Dis 2005 0.81
83 [Reduced expression of the E3-ubiquitin ligase seven in absentia homologue (SIAH)-1 in human hepatocellular carcinoma]. Verh Dtsch Ges Pathol 2007 0.81
84 Tumour necrosis factor (TNF) production by T cell receptor-primed T lymphocytes is a target for low dose methotrexate in rheumatoid arthritis. Clin Exp Immunol 1999 0.81
85 The role of insulin-like growth factor II in the malignant transformation of rat liver oval cells. Hepatology 1997 0.81
86 Structural requirements of research tissue banks derived from standardized project surveillance. Virchows Arch 2012 0.81
87 Cyclospora cayetanensis: first imported infections in Germany. Infection 1997 0.80
88 [Lobular carcinoma in situ (LCIS): risk factor and precursor of invasive lobular breast cancer]. Verh Dtsch Ges Pathol 2007 0.80
89 Establishment and characterization of a nontumorigenic cell line derived from a human hepatocellular adenoma expressing hepatocyte-specific markers. Exp Cell Res 1997 0.80
90 T cell receptor Vbeta chain restriction and preferred CDR3 motifs of liver-kidney microsomal antigen (LKM-1)-reactive T cells from autoimmune hepatitis patients. Liver 2001 0.80
91 Signaling networks in human hepatocarcinogenesis--novel aspects and therapeutic options. Prog Mol Biol Transl Sci 2010 0.80
92 [Special research field SFB/TRR77: liver cancer. From molecular pathology to targeted therapy]. Pathologe 2013 0.80
93 Absence of therapeutically relevant c-erbB-2 expression in human hepatocellular carcinomas. Oncol Rep 2001 0.80
94 Possible involvement of the retinoblastoma gene in undifferentiated sinonasal carcinoma. Cancer 1990 0.80
95 [BRAF mutation detection in metastatic melanoma]. Pathologe 2012 0.79
96 The German guideline for the management of hepatitis B virus infection: short version. J Viral Hepat 2008 0.79
97 [Prophylaxis, Diagnosis and Therapy of Hepatitis-B-Virus-(HBV-)Infection: upgrade of the guideline, AWMF-Register 021/011]. Z Gastroenterol 2007 0.79
98 Large-scale N-terminal deletions but not point mutations stabilize beta-catenin in small bowel carcinomas, suggesting divergent molecular pathways of small and large intestinal carcinogenesis. J Pathol 2008 0.78
99 Gains of chromosome region 3q26 in intraepithelial neoplasia and invasive squamous cell carcinoma of the vulva are frequent and independent of HPV status. J Clin Pathol 2008 0.78
100 Expression of acyl-CoA synthetase 5 in human endometrium and in endometrioid adenocarcinomas. Histopathology 2005 0.78
101 Differentiated expression patterns of growth factors in routine formalin-fixed endomyocardial biopsies in the early postoperative phase after heart transplantation. Transplant Proc 2007 0.78
102 [Renal oncocytoma with metastasis from breast carcinoma: a contribution to the differential diagnosis of tumourous lesions of the kidney]. Pathologe 2006 0.78
103 Circulating ICAM-1 (sCD54) and LFA-3 (sCD58) in chronic hepatitis B--a longitudinal study in patients treated with interferon-alpha. Z Gastroenterol 1997 0.78
104 [Insulin-like growth factor (IGF)-signalling pathway components are potential therapeutic targets in the treatment of human hepatocellular carcinoma]. Verh Dtsch Ges Pathol 2007 0.78
105 An institutional study on thymomas and thymic carcinomas: experience in 77 patients. Thorac Cardiovasc Surg 2008 0.78
106 [Malignant lymphomas of the liver: new diagnostic algorithms]. Pathologe 2006 0.78
107 [Lipid droplet-associated proteins in steatosis. Effects of induction and siRNA-mediated downregulation of PAT proteins in cell culture models of hepatocyte steatosis]. Pathologe 2010 0.77
108 [Recent developments in biopsy diagnosis of early and undefined liver tumors]. Z Gastroenterol 2009 0.77
109 [Evaluation of her-2/neu amplification/overexpression in OSCC with fluorescence in situ hybridization (FISH) and immunohistochemistry]. Mund Kiefer Gesichtschir 2003 0.77
110 Antisense phosphorothioate oligonucleotides to the p65 subunit of NF-kappaB abrogate fulminant septic shock induced by S. typhimurium in mice. Scand J Immunol 2001 0.77
111 Colonization of adrenal glands and ovaries of mice by variants of HSV 1 and 2. II. Histopathological, immunohistochemical and in situ hybridization studies. Arch Virol 1991 0.77
112 Anti-neutrophil cytoplasmic antibodies in a rat model of trinitrobenzenesulphonic acid-induced liver injury. Eur J Clin Invest 1999 0.77
113 [Guidelines of the German Society of Digestive and Metabolic Diseases for diagnosis and therapy of hepatocellular carcinoma. German Society of Digestive and Metabolic Diseases]. Z Gastroenterol 1999 0.77
114 [Molecular pathogenesis of hepatocellular carcinoma: new therapeutic approaches and predictive pathology]. Pathologe 2007 0.77
115 Hepatitis C virus associated primary hepatocellular carcinoma in a noncirrhotic liver. Clin Investig 1993 0.77
116 [The PEA-15 protein induces resistance against glucose deprivation-induced cell death via the ERK/MAP kinase pathway]. Verh Dtsch Ges Pathol 2007 0.77
117 [Chromosomal instability, microsatellite instability and CpG island methylator phenotype: roles in small intestinal carcinogenesis]. Pathologe 2011 0.77
118 [Primary sarcomas and sarcoma metastases in the liver: morphological and molecular aspects]. Pathologe 2006 0.76
119 Nonparenchymal cells in chronically hyperinsulinemic liver acini of diabetic rats, with special regard to hepatic stellate cells. J Hepatol 1998 0.76
120 In PSC with colitis treated with UDCA, most colonic carcinomas develop in the first years after the start of treatment. Dig Dis Sci 2011 0.76
121 [S100 protein positive sustentacular cells in pulmonary carcinoids and thoracic paragangliomas: differential diagnostic and prognostic evaluation]. Pathologe 2010 0.76
122 The early immune response in the liver of BALB/c mice infected with S. typhimurium. Scand J Immunol 2000 0.76
123 De novo CSF3R mutation associated with transformation of myeloproliferative neoplasm to atypical CML. Ann Hematol 2015 0.76
124 [Liver biopsy in chronic hepatitis C. Histopathology, molecular diagnostic analysis, and implications for therapeutic management]. Pathologe 2001 0.75
125 [Frozen section diagnostics in visceral surgery. Liver, bile ducts and pancreas]. Pathologe 2012 0.75
126 [Comment on the consensus report, "Treatment of chronic B/D viral hepatitis and acute and chronic C virus hepatitis"]. Z Gastroenterol 1998 0.75
127 Characterization of metaplastic and heterotopic epithelia in the human gastrointestinal tract by the expression pattern of acyl-CoA synthetase 5. Histol Histopathol 2005 0.75
128 Hepatocellular carcinoma in a patient with hereditary hemochromatosis and noncirrhotic liver. A case report. Pathol Res Pract 1999 0.75
129 Two malignant tumours in the anterior mediastinum positive for CD5. BMJ Case Rep 2010 0.75
130 Vitamin A-induced cholestatic hepatitis: a case report. Z Gastroenterol 2007 0.75
131 Complete reversal of FK 506 induced diabetes in a liver transplant recipient by change of immunosuppression to cyclosporine A. Z Gastroenterol 1996 0.75
132 [Histopathological diagnose of non-alcoholic and alcoholic fatty liver disease]. Z Gastroenterol 2010 0.75
133 Clinical picture: Bacterial translocation in neutropenic sepsis. Lancet 2001 0.75
134 Amyotrophic lateral sclerosis: evidence for intact hepatocyte growth factor/met signalling axis. Cytokine 2001 0.75
135 [Pleomorphic high-grade soft tissue sarcomas: is the subclassification up to date?]. Pathologe 2011 0.75
136 Hepatic manifestation of hemolytic uremic syndrome in an allogeneic bone marrow transplant recipient. Z Gastroenterol 1995 0.75
137 [Expression of lectin binding sites as a prognostic parameter in mouth mucosa carcinomas]. Mund Kiefer Gesichtschir 2001 0.75
138 [Pathology: pacemaker of advances in medicine]. Dtsch Med Wochenschr 2013 0.75
139 [Hepatitis C virus and autoimmune hepatitis: coincidence or causal relationship?]. Verh Dtsch Ges Pathol 1996 0.75
140 Impact of apoptosis in acute rejection episodes after heart transplantation: immunohistochemical examination of right ventricular myocardial biopsies. Transplant Proc 2008 0.75
141 [Pathogenesis and pathomorphology of chronic viral hepatitis]. Verh Dtsch Ges Pathol 2005 0.75
142 [Isolated tuberculosis of the liver coincident with renal cell carcinoma]. Aktuelle Radiol 1997 0.75
143 [Insulin-like growth factor (IGF)-II in human hepatocarcinogenesis--a potential therapeutic target?]. Verh Dtsch Ges Pathol 2005 0.75
144 [Primary sclerosing cholangitis - challenges for all. The German Study Group PSC]. Z Gastroenterol 2011 0.75
145 [The morphologic variants of KSHV/HHV 8-associated lymphoproliferations]. Pathologe 2007 0.75
146 [Molecular pathology of sarcomas. Update on the research group "Molecular Diagnosis of Sarcomas"]. Pathologe 2010 0.75
147 Sustained elimination of hepatitis B virus from serum induced in a patient with chronic hepatitis B and advanced human immunodeficiency virus infection. Clin Investig 1994 0.75
148 [Persistent pulmonary opacification as a sequela of portopulmonary shunt in portal vein thrombosis]. Z Gastroenterol 1998 0.75
149 Persistent expression of hepatitis C virus genome in primary tumor and adrenal metastasis of a hepatocellular carcinoma developed in a non-cirrhotic liver. J Hepatol 1996 0.75
150 [Hepatocellular carcinoma: novel molecular aspects for differential diagnosis and therapy]. Verh Dtsch Ges Pathol 2006 0.75
151 [Significance of cyclooxygenase-2 as a chemotherapeutic target in hepatocellular carcinoma]. Verh Dtsch Ges Pathol 2007 0.75
152 [Student Academy of the German Society of Pathology]. Pathologe 2013 0.75
153 A critical function of USF in HGF gene regulation mediated by a multiconsensus region. Biochem Biophys Res Commun 2002 0.75
154 [The rise of hepato-oncology]. Z Gastroenterol 2009 0.75
155 [Bilateral kidney enlargement with kidney failure. Manifestation of primary extranodal B-cell lymphoma after long-term immunosuppression]. Med Klin (Munich) 1994 0.75
156 Herpes simplex virus hepatitis and related problems. Int Rev Exp Pathol 1994 0.75
157 [Neoplasms of the skin]. Pathologe 2015 0.75
158 [Quality and quantity in hepatopathology. Diagnostic and clinically relevant grading for non-tumourous liver diseases]. Pathologe 2008 0.75