Published in RNA on November 01, 1997
Yeast exosome mutants accumulate 3'-extended polyadenylated forms of U4 small nuclear RNA and small nucleolar RNAs. Mol Cell Biol (2000) 4.57
A box H/ACA small nucleolar RNA-like domain at the human telomerase RNA 3' end. Mol Cell Biol (1999) 4.51
The biogenesis and regulation of telomerase holoenzymes. Nat Rev Mol Cell Biol (2006) 2.94
Pre-mRNA processing factors are required for nuclear export. RNA (2000) 2.76
Yeast telomerase RNA: a flexible scaffold for protein subunits. Proc Natl Acad Sci U S A (2004) 2.52
Essential functions of amino-terminal domains in the yeast telomerase catalytic subunit revealed by selection for viable mutants. Genes Dev (1999) 2.30
Dual requirement for yeast hnRNP Nab2p in mRNA poly(A) tail length control and nuclear export. EMBO J (2002) 2.07
Essential regions of Saccharomyces cerevisiae telomerase RNA: separate elements for Est1p and Est2p interaction. Mol Cell Biol (2002) 1.89
Depletion of yeast RNase III blocks correct U2 3' end formation and results in polyadenylated but functional U2 snRNA. EMBO J (1998) 1.88
Telomerase RNA function in recombinant Tetrahymena telomerase. Genes Dev (1999) 1.83
Polyadenylation of stable RNA precursors in vivo. Proc Natl Acad Sci U S A (1998) 1.81
Low abundance of telomerase in yeast: implications for telomerase haploinsufficiency. RNA (2006) 1.74
Everything you ever wanted to know about Saccharomyces cerevisiae telomeres: beginning to end. Genetics (2012) 1.56
Differential suppression of DNA repair deficiencies of Yeast rad50, mre11 and xrs2 mutants by EXO1 and TLC1 (the RNA component of telomerase). Genetics (2002) 1.51
Functional analysis of yeast snoRNA and snRNA 3'-end formation mediated by uncoupling of cleavage and polyadenylation. Mol Cell Biol (2002) 1.49
cis- and trans-Acting determinants of transcription termination by yeast RNA polymerase II. Mol Cell Biol (2006) 1.47
Biogenesis of telomerase ribonucleoproteins. RNA (2012) 1.47
U snRNP assembly in yeast involves the La protein. EMBO J (2000) 1.44
Euplotes telomerase contains an La motif protein produced by apparent translational frameshifting. EMBO J (2000) 1.38
Intracellular trafficking of yeast telomerase components. EMBO Rep (2002) 1.34
Human telomerase RNA-protein interactions. Nucleic Acids Res (2001) 1.29
Stable expression in yeast of the mature form of human telomerase RNA depends on its association with the box H/ACA small nucleolar RNP proteins Cbf5p, Nhp2p and Nop10p. Nucleic Acids Res (2001) 1.29
TLC1 RNA nucleo-cytoplasmic trafficking links telomerase biogenesis to its recruitment to telomeres. EMBO J (2008) 1.24
A template-proximal RNA paired element contributes to Saccharomyces cerevisiae telomerase activity. RNA (2003) 1.24
Heterogeneous nuclear ribonucleoproteins C1 and C2 associate with the RNA component of human telomerase. Mol Cell Biol (2000) 1.22
Two RNA subunits and POT1a are components of Arabidopsis telomerase. Proc Natl Acad Sci U S A (2010) 1.20
A genome-wide screen for essential yeast genes that affect telomere length maintenance. Nucleic Acids Res (2009) 1.20
Yeast Nrd1, Nab3, and Sen1 transcriptome-wide binding maps suggest multiple roles in post-transcriptional RNA processing. RNA (2011) 1.17
Biogenesis of yeast telomerase depends on the importin mtr10. Mol Cell Biol (2002) 1.06
Telomerase core components protect Candida telomeres from aberrant overhang accumulation. Proc Natl Acad Sci U S A (2007) 1.01
Stimulation of yeast telomerase activity by the ever shorter telomere 3 (Est3) subunit is dependent on direct interaction with the catalytic protein Est2. J Biol Chem (2011) 1.01
Cdc42p GTPase regulates the budded-to-hyphal-form transition and expression of hypha-specific transcripts in Candida albicans. Eukaryot Cell (2004) 0.98
Multiple yeast genes, including Paf1 complex genes, affect telomere length via telomerase RNA abundance. Mol Cell Biol (2008) 0.96
The C-terminal region of the exosome-associated protein Rrp47 is specifically required for box C/D small nucleolar RNA 3'-maturation. J Biol Chem (2010) 0.92
Budding yeast telomerase RNA transcription termination is dictated by the Nrd1/Nab3 non-coding RNA termination pathway. Nucleic Acids Res (2012) 0.91
Molecular characterization at the RNA and gene levels of U3 snoRNA from a unicellular green alga, Chlamydomonas reinhardtii. Nucleic Acids Res (2000) 0.91
Posttranslational phosphorylation and ubiquitination of the Saccharomyces cerevisiae Poly(A) polymerase at the S/G(2) stage of the cell cycle. Mol Cell Biol (2000) 0.87
Specific features of telomerase RNA from Hansenula polymorpha. RNA (2013) 0.83
Novel connections between DNA replication, telomere homeostasis, and the DNA damage response revealed by a genome-wide screen for TEL1/ATM interactions in Saccharomyces cerevisiae. Genetics (2013) 0.82
Identification of telomerase RNAs from filamentous fungi reveals conservation with vertebrates and yeasts. PLoS One (2013) 0.82
A trans-spliced telomerase RNA dictates telomere synthesis in Trypanosoma brucei. Cell Res (2013) 0.82
Systematic analysis of telomere length and somatic alterations in 31 cancer types. Nat Genet (2017) 0.82
The Sm complex is required for the processing of non-coding RNAs by the exosome. PLoS One (2013) 0.81
Evolution of TERT-interacting lncRNAs: expanding the regulatory landscape of telomerase. Front Genet (2015) 0.80
RNA connectivity requirements between conserved elements in the core of the yeast telomerase RNP. EMBO J (2013) 0.80
Cell cycle-dependent transcription factors control the expression of yeast telomerase RNA. RNA (2013) 0.79
Prevalent and distinct spliceosomal 3'-end processing mechanisms for fungal telomerase RNA. Nat Commun (2015) 0.78
Peculiarities of Yeasts and Human Telomerase RNAs Processing. Acta Naturae (2017) 0.75
The putative Leishmania telomerase RNA (LeishTER) undergoes trans-splicing and contains a conserved template sequence. PLoS One (2014) 0.75
The yeast telomerase RNA, TLC1, participates in two distinct modes of TLC1-TLC1 association processes in vivo. PeerJ (2016) 0.75
Crystal structure of a group I ribozyme domain: principles of RNA packing. Science (1996) 13.99
Telomerase catalytic subunit homologs from fission yeast and human. Science (1997) 12.35
Self-splicing RNA: autoexcision and autocyclization of the ribosomal RNA intervening sequence of Tetrahymena. Cell (1982) 12.12
Reverse transcriptase motifs in the catalytic subunit of telomerase. Science (1997) 10.10
Monovalent cation-induced structure of telomeric DNA: the G-quartet model. Cell (1989) 7.83
Pot1, the putative telomere end-binding protein in fission yeast and humans. Science (2001) 6.95
Secondary structure of the circular form of the Tetrahymena rRNA intervening sequence: a technique for RNA structure analysis using chemical probes and reverse transcriptase. Proc Natl Acad Sci U S A (1985) 6.48
Biological catalysis by RNA. Annu Rev Biochem (1986) 5.69
Inhibition of telomerase by G-quartet DNA structures. Nature (1991) 5.38
Secondary structure of the Tetrahymena ribosomal RNA intervening sequence: structural homology with fungal mitochondrial intervening sequences. Proc Natl Acad Sci U S A (1983) 4.78
Regulation of telomere length and function by a Myb-domain protein in fission yeast. Nature (1997) 4.49
In vitro splicing of the ribosomal RNA precursor of Tetrahymena: involvement of a guanosine nucleotide in the excision of the intervening sequence. Cell (1981) 4.42
The generality of self-splicing RNA: relationship to nuclear mRNA splicing. Cell (1986) 4.23
Defining the inside and outside of a catalytic RNA molecule. Science (1989) 3.82
The chemistry of self-splicing RNA and RNA enzymes. Science (1987) 3.72
The intervening sequence RNA of Tetrahymena is an enzyme. Science (1986) 3.71
Telomerase RNAs of different ciliates have a common secondary structure and a permuted template. Genes Dev (1994) 3.60
Saccharomyces cerevisiae telomerase is an Sm small nuclear ribonucleoprotein particle. Nature (1999) 3.59
RNA tertiary structure mediation by adenosine platforms. Science (1996) 3.40
Sequence-specific endoribonuclease activity of the Tetrahymena ribozyme: enhanced cleavage of certain oligonucleotide substrates that form mismatched ribozyme-substrate complexes. Biochemistry (1988) 3.33
Visualizing the higher order folding of a catalytic RNA molecule. Science (1991) 3.19
Structural conventions for group I introns. Nucleic Acids Res (1987) 3.12
Three Ever Shorter Telomere (EST) genes are dispensable for in vitro yeast telomerase activity. Proc Natl Acad Sci U S A (1997) 3.11
A preorganized active site in the crystal structure of the Tetrahymena ribozyme. Science (1998) 3.01
Nuclear proteins that bind the pre-mRNA 3' splice site sequence r(UUAG/G) and the human telomeric DNA sequence d(TTAGGG)n. Mol Cell Biol (1993) 2.84
Purification of telomerase from Euplotes aediculatus: requirement of a primer 3' overhang. Proc Natl Acad Sci U S A (1996) 2.80
Autocatalytic cyclization of an excised intervening sequence RNA is a cleavage-ligation reaction. Nature (1983) 2.79
Analysis of the structure of Tetrahymena nuclear RNAs in vivo: telomerase RNA, the self-splicing rRNA intron, and U2 snRNA. RNA (1995) 2.78
Catalysis of RNA cleavage by the Tetrahymena thermophila ribozyme. 1. Kinetic description of the reaction of an RNA substrate complementary to the active site. Biochemistry (1990) 2.77
RNA splicing: three themes with variations. Cell (1983) 2.76
Telomerase and DNA end replication: no longer a lagging strand problem? Science (1995) 2.67
Minor-groove recognition of double-stranded RNA by the double-stranded RNA-binding domain from the RNA-activated protein kinase PKR. Biochemistry (1996) 2.65
Metal ion catalysis in the Tetrahymena ribozyme reaction. Nature (1993) 2.62
Telomeric DNA-protein interactions of Oxytricha macronuclear DNA. Genes Dev (1987) 2.61
Reversing time: origin of telomerase. Cell (1998) 2.58
An independently folding domain of RNA tertiary structure within the Tetrahymena ribozyme. Biochemistry (1993) 2.58
Two modes of survival of fission yeast without telomerase. Science (1998) 2.57
Electron microscopy of DNA crosslinked with trimethylpsoralen: test of the secondary structure of eukaryotic inverted repeat sequences. Proc Natl Acad Sci U S A (1976) 2.57
The Tetrahymena ribozyme acts like an RNA restriction endonuclease. Nature (1987) 2.53
GAAA tetraloop and conserved bulge stabilize tertiary structure of a group I intron domain. J Mol Biol (1994) 2.50
Structural basis of the enhanced stability of a mutant ribozyme domain and a detailed view of RNA--solvent interactions. Structure (2001) 2.49
One binding site determines sequence specificity of Tetrahymena pre-rRNA self-splicing, trans-splicing, and RNA enzyme activity. Cell (1986) 2.48
A labile phosphodiester bond at the ligation junction in a circular intervening sequence RNA. Science (1984) 2.46
Essential functions of amino-terminal domains in the yeast telomerase catalytic subunit revealed by selection for viable mutants. Genes Dev (1999) 2.30
New reactions of the ribosomal RNA precursor of Tetrahymena and the mechanism of self-splicing. J Mol Biol (1986) 2.24
The beta subunit of Oxytricha telomere-binding protein promotes G-quartet formation by telomeric DNA. Cell (1993) 2.23
Aminoacyl esterase activity of the Tetrahymena ribozyme. Science (1992) 2.06
Peptide bond formation by in vitro selected ribozymes. Nature (1997) 2.05
Reverse self-splicing of the tetrahymena group I intron: implication for the directionality of splicing and for intron transposition. Cell (1989) 2.01
Ribozyme-catalyzed and nonenzymatic reactions of phosphate diesters: rate effects upon substitution of sulfur for a nonbridging phosphoryl oxygen atom. Biochemistry (1991) 1.99
Chromatin structure of the molecular ends of Oxytricha macronuclear DNA: phased nucleosomes and a telomeric complex. Cell (1984) 1.97
Specific interaction between the self-splicing RNA of Tetrahymena and its guanosine substrate: implications for biological catalysis by RNA. Nature (1984) 1.96
The anchor site of telomerase from Euplotes aediculatus revealed by photo-cross-linking to single- and double-stranded DNA primers. Mol Cell Biol (1997) 1.94
Telomerase and the maintenance of chromosome ends. Curr Opin Cell Biol (1999) 1.94
Protection of telomeres by the Ku protein in fission yeast. Mol Biol Cell (2000) 1.94
Replication of the extrachromosomal ribosomal RNA genes of Tetrahymena thermophilia. Nucleic Acids Res (1981) 1.92
The intervening sequence of the ribosomal RNA precursor is converted to a circular RNA in isolated nuclei of Tetrahymena. Cell (1981) 1.91
Direct measurement of oligonucleotide substrate binding to wild-type and mutant ribozymes from Tetrahymena. Proc Natl Acad Sci U S A (1990) 1.88
Telomerase RNA bound by protein motifs specific to telomerase reverse transcriptase. Mol Cell (2000) 1.87
Minor groove recognition of the conserved G.U pair at the Tetrahymena ribozyme reaction site. Science (1995) 1.86
Chromatin structure at the replication origins and transcription-initiation regions of the ribosomal RNA genes of Tetrahymena. Cell (1984) 1.82
Role of conserved sequence elements 9L and 2 in self-splicing of the Tetrahymena ribosomal RNA precursor. Cell (1986) 1.81
Three-dimensional model of the active site of the self-splicing rRNA precursor of Tetrahymena. Proc Natl Acad Sci U S A (1987) 1.77
Binding of the protein kinase PKR to RNAs with secondary structure defects: role of the tandem A-G mismatch and noncontiguous helixes. Biochemistry (1998) 1.76
Telomerase reverse transcriptase genes identified in Tetrahymena thermophila and Oxytricha trifallax. Proc Natl Acad Sci U S A (1998) 1.74
Tethering ribozymes to a retroviral packaging signal for destruction of viral RNA. Science (1993) 1.74
Photocrosslinking of 5-iodouracil-substituted RNA and DNA to proteins. Science (1993) 1.73
Cloning and expression of genes for the Oxytricha telomere-binding protein: specific subunit interactions in the telomeric complex. Cell (1991) 1.73
Ribozyme recognition of RNA by tertiary interactions with specific ribose 2'-OH groups. Nature (1991) 1.72
RNA substrate binding site in the catalytic core of the Tetrahymena ribozyme. Nature (1992) 1.71
Stereochemistry of RNA cleavage by the Tetrahymena ribozyme and evidence that the chemical step is not rate-limiting. Science (1989) 1.68
Effect of monovalent cation-induced telomeric DNA structure on the binding of Oxytricha telomeric protein. Nucleic Acids Res (1990) 1.67
RNA as a flexible scaffold for proteins: yeast telomerase and beyond. Cold Spring Harb Symp Quant Biol (2006) 1.65
Intermolecular exon ligation of the rRNA precursor of Tetrahymena: oligonucleotides can function as 5' exons. Cell (1985) 1.65
Catalysis of RNA cleavage by the Tetrahymena thermophila ribozyme. 2. Kinetic description of the reaction of an RNA substrate that forms a mismatch at the active site. Biochemistry (1990) 1.63
A model for the RNA-catalyzed replication of RNA. Proc Natl Acad Sci U S A (1986) 1.61
A mutant of Tetrahymena telomerase reverse transcriptase with increased processivity. J Biol Chem (2000) 1.60
Energetics and cooperativity of tertiary hydrogen bonds in RNA structure. Biochemistry (1999) 1.60
Ribozyme-mediated repair of defective mRNA by targeted, trans-splicing. Nature (1994) 1.59
A stem-loop of Tetrahymena telomerase RNA distant from the template potentiates RNA folding and telomerase activity. Biochemistry (2001) 1.58
A second catalytic metal ion in group I ribozyme. Nature (1997) 1.55
An electron microscopic study of mouse foldback DNA. Cell (1975) 1.53
Tertiary interactions with the internal guide sequence mediate docking of the P1 helix into the catalytic core of the Tetrahymena ribozyme. Biochemistry (1993) 1.52
Alternative secondary structures in the 5' exon affect both forward and reverse self-splicing of the Tetrahymena intervening sequence RNA. Biochemistry (1991) 1.51
Multiple folding pathways for the P4-P6 RNA domain. Biochemistry (2000) 1.51
Sites of circularization of the Tetrahymena rRNA IVS are determined by sequence and influenced by position and secondary structure. Nucleic Acids Res (1985) 1.50
Characterization of a G-quartet formation reaction promoted by the beta-subunit of the Oxytricha telomere-binding protein. Biochemistry (1993) 1.49
Self-splicing RNA: implications for evolution. Int Rev Cytol (1985) 1.49
An RNA internal loop acts as a hinge to facilitate ribozyme folding and catalysis. RNA (1997) 1.49
Ribozyme inhibitors: deoxyguanosine and dideoxyguanosine are competitive inhibitors of self-splicing of the Tetrahymena ribosomal ribonucleic acid precursor. Biochemistry (1986) 1.48
Iron(II)-ethylenediaminetetraacetic acid catalyzed cleavage of RNA and DNA oligonucleotides: similar reactivity toward single- and double-stranded forms. Biochemistry (1990) 1.47