Published in J Mol Evol on January 01, 1998
A functional-phylogenetic classification system for transmembrane solute transporters. Microbiol Mol Biol Rev (2000) 5.65
Communicating with calcium Plant Cell (1999) 3.96
Alpha-synuclein is part of a diverse and highly conserved interaction network that includes PARK9 and manganese toxicity. Nat Genet (2009) 3.59
Identification of a family of zinc transporter genes from Arabidopsis that respond to zinc deficiency. Proc Natl Acad Sci U S A (1998) 3.41
CopA: An Escherichia coli Cu(I)-translocating P-type ATPase. Proc Natl Acad Sci U S A (2000) 2.75
P-type ATPase heavy metal transporters with roles in essential zinc homeostasis in Arabidopsis. Plant Cell (2004) 2.49
Identification of ion-selectivity determinants in heavy-metal transport P1B-type ATPases. J Membr Biol (2003) 2.14
Inventory of the superfamily of P-type ion pumps in Arabidopsis. Plant Physiol (2001) 2.14
Genomic comparison of P-type ATPase ion pumps in Arabidopsis and rice. Plant Physiol (2003) 1.97
Structural biology of copper trafficking. Chem Rev (2009) 1.89
Identification of a calmodulin-regulated Ca2+-ATPase in the endoplasmic reticulum. Plant Physiol (1999) 1.84
Families of soft-metal-ion-transporting ATPases. J Bacteriol (1999) 1.83
The complete genome sequence of Cupriavidus metallidurans strain CH34, a master survivalist in harsh and anthropogenic environments. PLoS One (2010) 1.78
The functional role of beta subunits in oligomeric P-type ATPases. J Bioenerg Biomembr (2001) 1.75
Structure of a copper pump suggests a regulatory role for its metal-binding domain. Structure (2008) 1.74
Mechanism of Cu+-transporting ATPases: soluble Cu+ chaperones directly transfer Cu+ to transmembrane transport sites. Proc Natl Acad Sci U S A (2008) 1.65
AtHMA3, a P1B-ATPase allowing Cd/Zn/Co/Pb vacuolar storage in Arabidopsis. Plant Physiol (2008) 1.59
Identification of Thlaspi caerulescens genes that may be involved in heavy metal hyperaccumulation and tolerance. Characterization of a novel heavy metal transporting ATPase. Plant Physiol (2004) 1.58
The ACA4 gene of Arabidopsis encodes a vacuolar membrane calcium pump that improves salt tolerance in yeast. Plant Physiol (2000) 1.54
A structural overview of the plasma membrane Na+,K+-ATPase and H+-ATPase ion pumps. Nat Rev Mol Cell Biol (2011) 1.52
A gold standard set of mechanistically diverse enzyme superfamilies. Genome Biol (2006) 1.52
Whole-genome transcriptional analysis of heavy metal stresses in Caulobacter crescentus. J Bacteriol (2005) 1.49
Reconstitution of phospholipid translocase activity with purified Drs2p, a type-IV P-type ATPase from budding yeast. Proc Natl Acad Sci U S A (2009) 1.47
The plant plasma membrane proton pump ATPase: a highly regulated P-type ATPase with multiple physiological roles. Pflugers Arch (2008) 1.46
Phospholipid flippases: building asymmetric membranes and transport vesicles. Biochim Biophys Acta (2011) 1.46
A calcium-dependent protein kinase can inhibit a calmodulin-stimulated Ca2+ pump (ACA2) located in the endoplasmic reticulum of Arabidopsis. Proc Natl Acad Sci U S A (2000) 1.45
Chilling tolerance in Arabidopsis involves ALA1, a member of a new family of putative aminophospholipid translocases. Plant Cell (2000) 1.45
Regulation of HMG-CoA reductase degradation requires the P-type ATPase Cod1p/Spf1p. J Cell Biol (2000) 1.43
Structure of the two transmembrane Cu+ transport sites of the Cu+ -ATPases. J Biol Chem (2008) 1.43
Response of gram-positive bacteria to copper stress. J Biol Inorg Chem (2009) 1.42
Plasma membrane Ca2+ ATPases as dynamic regulators of cellular calcium handling. Ann N Y Acad Sci (2007) 1.41
Cod1p/Spf1p is a P-type ATPase involved in ER function and Ca2+ homeostasis. J Cell Biol (2002) 1.36
Structural similarities of Na,K-ATPase and SERCA, the Ca(2+)-ATPase of the sarcoplasmic reticulum. Biochem J (2001) 1.33
Arabidopsis HMA2, a divalent heavy metal-transporting P(IB)-type ATPase, is involved in cytoplasmic Zn2+ homeostasis. Plant Physiol (2004) 1.28
Plasma-membrane Ca(2+) pumps: structural diversity as the basis for functional versatility. Biochem Soc Trans (2007) 1.25
At-ACA8 encodes a plasma membrane-localized calcium-ATPase of Arabidopsis with a calmodulin-binding domain at the N terminus. Plant Physiol (2000) 1.22
Cd2+, Mn2+, Ni2+ and Se2+ toxicity to Saccharomyces cerevisiae lacking YPK9p the orthologue of human ATP13A2. Biochem Biophys Res Commun (2009) 1.21
Heteromeric interactions required for abundance and subcellular localization of human CDC50 proteins and class 1 P4-ATPases. J Biol Chem (2010) 1.20
ECA3, a Golgi-localized P2A-type ATPase, plays a crucial role in manganese nutrition in Arabidopsis. Plant Physiol (2007) 1.20
The transport mechanism of bacterial Cu+-ATPases: distinct efflux rates adapted to different function. Biometals (2011) 1.18
Identification of residues defining phospholipid flippase substrate specificity of type IV P-type ATPases. Proc Natl Acad Sci U S A (2012) 1.18
Yeast genes controlling responses to topogenic signals in a model transmembrane protein. Mol Biol Cell (2002) 1.15
The funnel approach to the precrystallization production of membrane proteins. J Mol Biol (2008) 1.15
Rice P1B-type heavy-metal ATPase, OsHMA9, is a metal efflux protein. Plant Physiol (2007) 1.14
Bacterial transition metal P(1B)-ATPases: transport mechanism and roles in virulence. Biochemistry (2011) 1.13
CDC50 proteins are critical components of the human class-1 P4-ATPase transport machinery. J Biol Chem (2010) 1.13
Pollen development and fertilization in Arabidopsis is dependent on the MALE GAMETOGENESIS IMPAIRED ANTHERS gene encoding a type V P-type ATPase. Genes Dev (2005) 1.12
Ancestral Ca2+ signaling machinery in early animal and fungal evolution. Mol Biol Evol (2011) 1.12
Horizontal gene transfer of PIB-type ATPases among bacteria isolated from radionuclide- and metal-contaminated subsurface soils. Appl Environ Microbiol (2006) 1.11
Diverse functional consequences of mutations in the Na+/K+-ATPase alpha2-subunit causing familial hemiplegic migraine type 2. J Biol Chem (2008) 1.11
Repeated evolution of the pyrrolizidine alkaloid-mediated defense system in separate angiosperm lineages. Plant Cell (2004) 1.11
Energization of transport processes in plants. roles of the plasma membrane H+-ATPase. Plant Physiol (2004) 1.09
Voltage dependence of the apparent affinity for external Na(+) of the backward-running sodium pump. J Gen Physiol (2001) 1.07
Intracellular targeting signals and lipid specificity determinants of the ALA/ALIS P4-ATPase complex reside in the catalytic ALA alpha-subunit. Mol Biol Cell (2010) 1.06
ATP13A2 regulates mitochondrial bioenergetics through macroautophagy. Neurobiol Dis (2011) 1.06
Protons and how they are transported by proton pumps. Pflugers Arch (2008) 1.05
Two distinctly localized p-type ATPases collaborate to maintain organelle homeostasis required for glycoprotein processing and quality control. Mol Biol Cell (2002) 1.04
Whole genome duplication and enrichment of metal cation transporters revealed by de novo genome sequencing of extremely halotolerant black yeast Hortaea werneckii. PLoS One (2013) 1.04
Purification and membrane reconstitution of catalytically active Menkes copper-transporting P-type ATPase (MNK; ATP7A). Biochem J (2007) 1.03
Intermediate phosphorylation reactions in the mechanism of ATP utilization by the copper ATPase (CopA) of Thermotoga maritima. J Biol Chem (2008) 1.03
A bimodular mechanism of calcium control in eukaryotes. Nature (2012) 1.02
Phosphosite mapping of P-type plasma membrane H+-ATPase in homologous and heterologous environments. J Biol Chem (2011) 1.02
Bioinformatic characterization of p-type ATPases encoded within the fully sequenced genomes of 26 eukaryotes. J Membr Biol (2009) 1.01
PMR1/SPCA Ca2+ pumps and the role of the Golgi apparatus as a Ca2+ store. Pflugers Arch (2003) 1.01
Cytotoxicity of hydrogen peroxide produced by Enterococcus faecium. Infect Immun (2004) 1.00
Chaperone-mediated Cu+ delivery to Cu+ transport ATPases: requirement of nucleotide binding. J Biol Chem (2009) 0.99
Role of flippases, scramblases and transfer proteins in phosphatidylserine subcellular distribution. Traffic (2014) 0.99
Transcriptional and functional analysis of oxalyl-coenzyme A (CoA) decarboxylase and formyl-CoA transferase genes from Lactobacillus acidophilus. Appl Environ Microbiol (2006) 0.99
A P-type ATPase importer that discriminates between essential and toxic transition metals. Proc Natl Acad Sci U S A (2009) 0.99
Cellular function and pathological role of ATP13A2 and related P-type transport ATPases in Parkinson's disease and other neurological disorders. Front Mol Neurosci (2014) 0.98
Evolution of plant p-type ATPases. Front Plant Sci (2012) 0.98
Characterization and structure of a Zn2+ and [2Fe-2S]-containing copper chaperone from Archaeoglobus fulgidus. J Biol Chem (2007) 0.97
The Ca2+ pumps of the endoplasmic reticulum and Golgi apparatus. Cold Spring Harb Perspect Biol (2011) 0.97
P4-ATPases: lipid flippases in cell membranes. Pflugers Arch (2014) 0.97
A combined zinc/cadmium sensor and zinc/cadmium export regulator in a heavy metal pump. J Biol Chem (2010) 0.96
Zn²⁺ dyshomeostasis caused by loss of ATP13A2/PARK9 leads to lysosomal dysfunction and alpha-synuclein accumulation. Hum Mol Genet (2013) 0.96
Nucleotide recognition by CopA, a Cu+-transporting P-type ATPase. EMBO J (2009) 0.95
Novel p-type ATPases mediate high-affinity potassium or sodium uptake in fungi. Eukaryot Cell (2004) 0.95
Molecular evidence for the evolution of metal homeostasis genes by lateral gene transfer in bacteria from the deep terrestrial subsurface. Appl Environ Microbiol (2004) 0.95
Diversity of the metal-transporting P1B-type ATPases. J Biol Inorg Chem (2014) 0.94
The putative aminophospholipid translocases, DNF1 and DNF2, are not required for 7-nitrobenz-2-oxa-1,3-diazol-4-yl-phosphatidylserine flip across the plasma membrane of Saccharomyces cerevisiae. J Biol Chem (2008) 0.93
Regulatory role of the N terminus of the vacuolar calcium-ATPase in cauliflower. Plant Physiol (2000) 0.93
Identification of a calmodulin-regulated soybean Ca(2+)-ATPase (SCA1) that is located in the plasma membrane. Plant Cell (2000) 0.93
New findings on evolution of metal homeostasis genes: evidence from comparative genome analysis of bacteria and archaea. Appl Environ Microbiol (2005) 0.93
Role for a P-type H+-ATPase in the acidification of the endocytic pathway of Trypanosoma cruzi. Biochem J (2005) 0.92
Plasma membrane calcium ATPases as novel candidates for therapeutic agent development. J Pharm Pharm Sci (2013) 0.91
The beta subunit of the Na+/K+-ATPase follows the conformational state of the holoenzyme. J Gen Physiol (2005) 0.91
Tracing cytoplasmic Ca(2+) ion and water access points in the Ca(2+)-ATPase. Biophys J (2012) 0.90
An unexpectedly high degree of specialization and a widespread involvement in sterol metabolism among the C. elegans putative aminophospholipid translocases. BMC Dev Biol (2008) 0.90
Identification of a hemerythrin-like domain in a P1B-type transport ATPase. Biochemistry (2010) 0.90
Characterization of cellular protective effects of ATP13A2/PARK9 expression and alterations resulting from pathogenic mutants. J Neurosci Res (2012) 0.89
Type IV P-type ATPases distinguish mono- versus diacyl phosphatidylserine using a cytofacial exit gate in the membrane domain. J Biol Chem (2013) 0.89
Comprehensive analysis of co-occurring domain sets in yeast proteins. BMC Genomics (2007) 0.89
A plasma membrane Ca2+ ATPase isoform at the postsynaptic density. Neuroscience (2010) 0.89
Modeling a dehalogenase fold into the 8-A density map for Ca(2+)-ATPase defines a new domain structure. Biophys J (2000) 0.89
ATP11B mediates platinum resistance in ovarian cancer. J Clin Invest (2013) 0.88
Cadmium accumulation and DNA homology with metal resistance genes in sulfate-reducing bacteria. Appl Environ Microbiol (2005) 0.88
Characterization of a Listeria monocytogenes Ca(2+) pump: a SERCA-type ATPase with only one Ca(2+)-binding site. J Biol Chem (2010) 0.88
ATP13A2/PARK9 regulates secretion of exosomes and α-synuclein. J Neurosci (2014) 0.88
Regulation of salt tolerance by Torulaspora delbrueckii calcineurin target Crz1p. Eukaryot Cell (2006) 0.88
Inventory of the superfamily of P-type ion pumps in Arabidopsis. Plant Physiol (2001) 2.14
Binding of 14-3-3 protein to the plasma membrane H(+)-ATPase AHA2 involves the three C-terminal residues Tyr(946)-Thr-Val and requires phosphorylation of Thr(947). J Biol Chem (1999) 1.87
Functional expression of plant plasma membrane H(+)-ATPase in yeast endoplasmic reticulum. J Biol Chem (1992) 1.68
A novel calmodulin-regulated Ca2+-ATPase (ACA2) from Arabidopsis with an N-terminal autoinhibitory domain. J Biol Chem (1998) 1.67
The 14-3-3 proteins associate with the plant plasma membrane H(+)-ATPase to generate a fusicoccin binding complex and a fusicoccin responsive system. Plant J (1998) 1.62
The 14-3-3 protein interacts directly with the C-terminal region of the plant plasma membrane H(+)-ATPase. Plant Cell (1997) 1.60
The ACA4 gene of Arabidopsis encodes a vacuolar membrane calcium pump that improves salt tolerance in yeast. Plant Physiol (2000) 1.54
Molecular aspects of higher plant P-type Ca(2+)-ATPases. Biochim Biophys Acta (2000) 1.53
C-terminal deletion analysis of plant plasma membrane H(+)-ATPase: yeast as a model system for solute transport across the plant plasma membrane. Plant Cell (1995) 1.46
Chilling tolerance in Arabidopsis involves ALA1, a member of a new family of putative aminophospholipid translocases. Plant Cell (2000) 1.45
A calmodulin-stimulated Ca2+-ATPase from plant vacuolar membranes with a putative regulatory domain at its N-terminus. FEBS Lett (1997) 1.41
14-3-3 proteins activate a plant calcium-dependent protein kinase (CDPK). FEBS Lett (1998) 1.22
At-ACA8 encodes a plasma membrane-localized calcium-ATPase of Arabidopsis with a calmodulin-binding domain at the N terminus. Plant Physiol (2000) 1.22
Metabolic modulation of transport coupling ratio in yeast plasma membrane H(+)-ATPase. J Biol Chem (1995) 1.11
Molecular dissection of the C-terminal regulatory domain of the plant plasma membrane H+-ATPase AHA2: mapping of residues that when altered give rise to an activated enzyme. Biochemistry (1999) 1.10
Protons and how they are transported by proton pumps. Pflugers Arch (2008) 1.05
Modified plant plasma membrane H(+)-ATPase with improved transport coupling efficiency identified by mutant selection in yeast. Plant J (1996) 0.99
Flippases: still more questions than answers. Cell Mol Life Sci (2008) 0.98
The regulatory domain of fungal and plant plasma membrane H(+)-ATPase. Acta Physiol Scand Suppl (1992) 0.97
Two-dimensional crystallization of a membrane protein on a detergent-resistant lipid monolayer. J Mol Biol (2001) 0.94
Abolishment of proton pumping and accumulation in the E1P conformational state of a plant plasma membrane H+-ATPase by substitution of a conserved aspartyl residue in transmembrane segment 6. J Biol Chem (2000) 0.86
Purification of a histidine-tagged plant plasma membrane H+-ATPase expressed in yeast. Protein Expr Purif (1998) 0.83
Phosphorylation-independent interaction between 14-3-3 protein and the plant plasma membrane H+-ATPase. Biochem Soc Trans (2002) 0.82
Mechanism of proton transport by plant plasma membrane proton ATPases. J Plant Res (2003) 0.82
A putative proton binding site of plasma membrane H(+)-ATPase identified through homology modelling. FEBS Lett (2001) 0.82
Expression of the sarcoplasmic reticulum Ca(2+)-ATPase in yeast. FEBS Lett (1994) 0.81
Large scale expression, purification and 2D crystallization of recombinant plant plasma membrane H+-ATPase. J Mol Biol (2001) 0.80
Studies of the plasma membrane H(+)-ATPase of yeast and plants. Biochem Soc Trans (1992) 0.79
Activation of the plant plasma membrane H+-ATPase. Is there a direct interaction between lysophosphatidylcholine and the C-terminal part of the enzyme? FEBS Lett (1996) 0.79
P-type H(+)- and Ca(2+)-ATPases in plant cells. Ann N Y Acad Sci (1997) 0.78
Purification of heterologously expressed plant plasma membrane H(+)-ATPase by Ni(2+)-affinity chromatography. Ann N Y Acad Sci (1997) 0.77
Activation of plant plasma membrane H(+)-ATPase by the non-ionic detergent Brij 58. Biochim Biophys Acta (1994) 0.76
Mutagenic study of residues in transmembrane helix 4, 5, and 6 of the plant plasma membrane P-type H+-ATPase. Ann N Y Acad Sci (2003) 0.75
Heterologous expression and purification of membrane-bound pyrophosphatases. Protein Expr Purif (2011) 0.75