Differential modulation of the uptake currents by redox interconversion of cysteine residues in the human neuronal glutamate transporter EAAC1.

PubWeight™: 0.77‹?›

🔗 View Article (PMID 9421181)

Published in Eur J Neurosci on October 01, 1997

Authors

D Trotti1, S Nussberger, A Volterra, M A Hediger

Author Affiliations

1: Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02115, USA.

Articles by these authors

Cloning and characterization of a mammalian proton-coupled metal-ion transporter. Nature (1997) 9.98

Cloning and characterization of an extracellular Ca(2+)-sensing receptor from bovine parathyroid. Nature (1993) 7.89

Knockout of glutamate transporters reveals a major role for astroglial transport in excitotoxicity and clearance of glutamate. Neuron (1996) 7.20

A novel duodenal iron-regulated transporter, IREG1, implicated in the basolateral transfer of iron to the circulation. Mol Cell (2000) 5.31

CXCR4-activated astrocyte glutamate release via TNFalpha: amplification by microglia triggers neurotoxicity. Nat Neurosci (2001) 4.12

Prostaglandins stimulate calcium-dependent glutamate release in astrocytes. Nature (1998) 4.03

Primary structure and functional characterization of a high-affinity glutamate transporter. Nature (1992) 3.69

Expression cloning of a mammalian proton-coupled oligopeptide transporter. Nature (1994) 3.54

A family of mammalian Na+-dependent L-ascorbic acid transporters. Nature (1999) 3.40

The human kidney low affinity Na+/glucose cotransporter SGLT2. Delineation of the major renal reabsorptive mechanism for D-glucose. J Clin Invest (1994) 3.30

Intracellular calcium oscillations in astrocytes: a highly plastic, bidirectional form of communication between neurons and astrocytes in situ. J Neurosci (1997) 3.18

CaT1 manifests the pore properties of the calcium-release-activated calcium channel. Nature (2001) 2.98

An iron-regulated ferric reductase associated with the absorption of dietary iron. Science (2001) 2.90

Molecular cloning, primary structure, and characterization of two members of the mammalian electroneutral sodium-(potassium)-chloride cotransporter family expressed in kidney. J Biol Chem (1994) 2.89

The preprotein translocation channel of the outer membrane of mitochondria. Cell (1998) 2.65

Expression cloning and characterization of a renal electrogenic Na+/HCO3- cotransporter. Nature (1997) 2.57

Human intestinal H+/peptide cotransporter. Cloning, functional expression, and chromosomal localization. J Biol Chem (1995) 2.32

Lipoxygenase metabolites of arachidonic acid as second messengers for presynaptic inhibition of Aplysia sensory cells. Nature (1987) 2.32

Polycystin-L is a calcium-regulated cation channel permeable to calcium ions. Nature (1999) 2.17

Molecular cloning and characterization of a channel-like transporter mediating intestinal calcium absorption. J Biol Chem (1999) 2.16

Primary structure and functional expression of a cDNA encoding the thiazide-sensitive, electroneutral sodium-chloride cotransporter. Proc Natl Acad Sci U S A (1993) 2.15

DNA sequence of the lactose operon: the lacA gene and the transcriptional termination region. Proc Natl Acad Sci U S A (1985) 2.05

Molecular characterization of a broad selectivity neutral solute channel. J Biol Chem (1998) 2.00

Cloning and functional expression of rNBC, an electrogenic Na(+)-HCO3- cotransporter from rat kidney. Am J Physiol (1998) 1.86

Cloning and characterization of the vasopressin-regulated urea transporter. Nature (1993) 1.84

The TOM core complex: the general protein import pore of the outer membrane of mitochondria. J Cell Biol (1999) 1.73

Iron-dependent regulation of the divalent metal ion transporter. FEBS Lett (2001) 1.68

Cloning of a rat kidney cDNA that stimulates dibasic and neutral amino acid transport and has sequence similarity to glucosidases. Proc Natl Acad Sci U S A (1992) 1.66

Glutamate transporters are oxidant-vulnerable: a molecular link between oxidative and excitotoxic neurodegeneration? Trends Pharmacol Sci (1998) 1.65

Characterization of a Na+/glucose cotransporter cloned from rabbit small intestine. J Membr Biol (1989) 1.64

Cellular and subcellular localization of the vasopressin- regulated urea transporter in rat kidney. Proc Natl Acad Sci U S A (1996) 1.51

Polycystin-2 is a novel cation channel implicated in defective intracellular Ca(2+) homeostasis in polycystic kidney disease. Biochem Biophys Res Commun (2001) 1.48

A novel system A isoform mediating Na+/neutral amino acid cotransport. J Biol Chem (2000) 1.47

A neuron-glia signalling network in the active brain. Curr Opin Neurobiol (2001) 1.44

Differential distribution of the glutamate transporters GLT-1 and GLAST in tanycytes of the third ventricle. J Comp Neurol (2001) 1.39

Molecular cloning of PEPT 2, a new member of the H+/peptide cotransporter family, from human kidney. Biochim Biophys Acta (1995) 1.39

Cloning of a human kidney cDNA with similarity to the sodium-glucose cotransporter. Am J Physiol (1992) 1.38

Molecular characteristics of Na(+)-coupled glucose transporters in adult and embryonic rat kidney. J Biol Chem (1995) 1.38

Electrogenic properties of the epithelial and neuronal high affinity glutamate transporter. J Biol Chem (1995) 1.37

Functional and molecular characterization of the human neutral solute channel aquaporin-9. Am J Physiol (1999) 1.37

Stoichiometry and pH dependence of the rabbit proton-dependent oligopeptide transporter PepT1. J Physiol (1997) 1.36

Cloning and characterization of a potassium-coupled amino acid transporter. Proc Natl Acad Sci U S A (1998) 1.34

Direct modulation of Aplysia S-K+ channels by a 12-lipoxygenase metabolite of arachidonic acid. Nature (1989) 1.34

Yeast SMF1 mediates H(+)-coupled iron uptake with concomitant uncoupled cation currents. J Biol Chem (1999) 1.33

Human calcium transport protein CaT1. Biochem Biophys Res Commun (2000) 1.33

Cloning and functional expression of a urea transporter from human bone marrow cells. J Biol Chem (1994) 1.33

SOD1 mutants linked to amyotrophic lateral sclerosis selectively inactivate a glial glutamate transporter. Nat Neurosci (1999) 1.32

The high affinity Na+/glucose cotransporter. Re-evaluation of function and distribution of expression. J Biol Chem (1994) 1.31

Tom40, the pore-forming component of the protein-conducting TOM channel in the outer membrane of mitochondria. J Cell Biol (2001) 1.31

Characterization of a rat Na+-dicarboxylate cotransporter. J Biol Chem (1998) 1.28

Comparative analysis of glutamate transporter expression in rat brain using differential double in situ hybridization. Anat Embryol (Berl) (1998) 1.27

Colonic epithelial hPepT1 expression occurs in inflammatory bowel disease: transport of bacterial peptides influences expression of MHC class 1 molecules. Gastroenterology (2001) 1.26

Expression of size-selected mRNA encoding the intestinal Na/glucose cotransporter in Xenopus laevis oocytes. Proc Natl Acad Sci U S A (1987) 1.25

Diurnal rhythmicity in intestinal SGLT-1 function, V(max), and mRNA expression topography. Am J Physiol Gastrointest Liver Physiol (2001) 1.22

Human vitamin C (L-ascorbic acid) transporter SVCT1. Biochem Biophys Res Commun (2000) 1.22

Peroxynitrite inhibits glutamate transporter subtypes. J Biol Chem (1996) 1.21

Cloning and regulation of expression of the rat kidney urea transporter (rUT2). J Clin Invest (1995) 1.18

Expression of mRNA (D2) encoding a protein involved in amino acid transport in S3 proximal tubule. Am J Physiol (1992) 1.18

Localization of the Na+/glucose cotransporter gene SGLT2 to human chromosome 16 close to the centromere. Genomics (1993) 1.17

Amyotrophic lateral sclerosis-linked glutamate transporter mutant has impaired glutamate clearance capacity. J Biol Chem (2001) 1.17

Expression cloning using Xenopus laevis oocytes. Methods Enzymol (1998) 1.16

CaT1 expression correlates with tumor grade in prostate cancer. Biochem Biophys Res Commun (2001) 1.16

Distribution of the glutamate transporters GLAST and GLT-1 in rat circumventricular organs, meninges, and dorsal root ganglia. J Comp Neurol (2000) 1.14

Recognition of preproteins by the isolated TOM complex of mitochondria. EMBO J (2000) 1.12

Focal degeneration of astrocytes in amyotrophic lateral sclerosis. Cell Death Differ (2008) 1.11

Na/HCO3 cotransporters in rat brain: expression in glia, neurons, and choroid plexus. J Neurosci (2000) 1.10

Functional roles of histidine and tyrosine residues in the H(+)-peptide transporter PepT1. Biochem Biophys Res Commun (2000) 1.10

Symmetry of H+ binding to the intra- and extracellular side of the H+-coupled oligopeptide cotransporter PepT1. J Biol Chem (1997) 1.09

A rat kidney-specific calcium transporter in the distal nephron. J Biol Chem (2000) 1.08

hPepT1-mediated epithelial transport of bacteria-derived chemotactic peptides enhances neutrophil-epithelial interactions. J Clin Invest (1998) 1.08

A new family of neurotransmitter transporters: the high-affinity glutamate transporters. FASEB J (1993) 1.08

Molecular and functional analysis of SDCT2, a novel rat sodium-dependent dicarboxylate transporter. J Clin Invest (1999) 1.07

Cloning and chromosomal localization of a human kidney cDNA involved in cystine, dibasic, and neutral amino acid transport. J Clin Invest (1993) 1.07

Small intestine hexose transport in experimental diabetes. Increased transporter mRNA and protein expression in enterocytes. J Clin Invest (1994) 1.07

Complete amino acid sequence of steer liver microsomal NADH-cytochrome b5 reductase. J Biol Chem (1985) 1.06

The 4F2 antigen heavy chain induces uptake of neutral and dibasic amino acids in Xenopus oocytes. J Biol Chem (1992) 1.06

Transport function of the naturally occurring pathogenic polycystin-2 mutant, R742X. Biochem Biophys Res Commun (2001) 1.06

Molecular characteristics of mammalian and insect amino acid transporters: implications for amino acid homeostasis. J Exp Biol (1997) 1.05

Distribution of peptide transporter PEPT2 mRNA in the rat nervous system. Anat Embryol (Berl) (1999) 1.04

Expression and characterization of the intestinal Na+/glucose cotransporter in COS-7 cells. Biochim Biophys Acta (1990) 1.03

Cloning and characterization of the urea transporter UT3: localization in rat kidney and testis. J Clin Invest (1997) 1.02

Synaptic modulation by astrocytes via Ca2+-dependent glutamate release. Neuroscience (2008) 1.01

Segmental localization of urea transporter mRNAs in rat kidney. Am J Physiol (1997) 1.01

Astrocytes as active participants of glutamatergic function and regulators of its homeostasis. Adv Exp Med Biol (1999) 1.00

Neuronal and glial glutamate transporters possess an SH-based redox regulatory mechanism. Eur J Neurosci (1997) 1.00

The amino acid transport system y+L/4F2hc is a heteromultimeric complex. FASEB J (1998) 1.00

The neuronal and epithelial human high affinity glutamate transporter. Insights into structure and mechanism of transport. J Biol Chem (1994) 1.00

Mammalian ion-coupled solute transporters. J Physiol (1995) 0.99

Metal ion transporters in mammals: structure, function and pathological implications. J Physiol (1999) 0.99

Non-synaptic localization of the glutamate transporter EAAC1 in cultured hippocampal neurons. Eur J Neurosci (1997) 0.99

Immunogold detection of L-glutamate and D-serine in small synaptic-like microvesicles in adult hippocampal astrocytes. Cereb Cortex (2011) 0.99

Molecular cloning and characterization of the vasopressin-regulated urea transporter of rat kidney collecting ducts. J Clin Invest (1996) 0.99

Structural conservation of the genes encoding CaT1, CaT2, and related cation channels. Genomics (2001) 0.99

Stoichiometry and kinetics of the high-affinity H+-coupled peptide transporter PepT2. J Biol Chem (1999) 0.97

The elusive transporters with a high affinity for glutamate. Trends Neurosci (1993) 0.97