Published in J Clin Invest on January 01, 1998
CD44 cell adhesion molecules. Mol Pathol (1999) 2.89
Higher levels of CRP, D-dimer, IL-6, and hyaluronic acid before initiation of antiretroviral therapy (ART) are associated with increased risk of AIDS or death. J Infect Dis (2011) 2.88
Hyaluronan as an immune regulator in human diseases. Physiol Rev (2011) 2.74
Antibodies to CD44 and integrin alpha4, but not L-selectin, prevent central nervous system inflammation and experimental encephalomyelitis by blocking secondary leukocyte recruitment. Proc Natl Acad Sci U S A (1999) 1.98
Interaction of CD44 and hyaluronan is the dominant mechanism for neutrophil sequestration in inflamed liver sinusoids. J Exp Med (2008) 1.84
Functional activation of lymphocyte CD44 in peripheral blood is a marker of autoimmune disease activity. J Clin Invest (1998) 1.74
Development of a peptide inhibitor of hyaluronan-mediated leukocyte trafficking. J Exp Med (2000) 1.65
RHAMM, a receptor for hyaluronan-mediated motility, compensates for CD44 in inflamed CD44-knockout mice: a different interpretation of redundancy. Proc Natl Acad Sci U S A (2004) 1.52
Exogenous and endogenous hyaluronic acid reduces HIV infection of CD4(+) T cells. Immunol Cell Biol (2014) 1.46
A role for CD44 in an antigen-induced murine model of pulmonary eosinophilia. J Clin Invest (2003) 1.36
CD44 deficiency leads to enhanced neutrophil migration and lung injury in Escherichia coli pneumonia in mice. Am J Pathol (2002) 1.28
Anti-inflammatory and chondroprotective effect of TSG-6 (tumor necrosis factor-alpha-stimulated gene-6) in murine models of experimental arthritis. Am J Pathol (2001) 1.27
The CD44-initiated pathway of T-cell extravasation uses VLA-4 but not LFA-1 for firm adhesion. J Clin Invest (2000) 1.25
Hyaluronan and hyaluronidase in genitourinary tumors. Front Biosci (2008) 1.24
Induction of resistance to diabetes in non-obese diabetic mice by targeting CD44 with a specific monoclonal antibody. Proc Natl Acad Sci U S A (2000) 1.20
Suppressor activity and potency among regulatory T cells is discriminated by functionally active CD44. Blood (2005) 1.19
Lymphotoxin-alpha contributes to lymphangiogenesis. Blood (2010) 1.19
Expression and role of the hyaluronan receptor RHAMM in inflammation after bleomycin injury. Am J Respir Cell Mol Biol (2005) 1.18
Synergistic effects of SDF-1α chemokine and hyaluronic acid release from degradable hydrogels on directing bone marrow derived cell homing to the myocardium. Biomaterials (2012) 1.18
Enforced hematopoietic cell E- and L-selectin ligand (HCELL) expression primes transendothelial migration of human mesenchymal stem cells. Proc Natl Acad Sci U S A (2011) 1.14
High-molecular-weight hyaluronan is a novel inhibitor of pulmonary vascular leakiness. Am J Physiol Lung Cell Mol Physiol (2010) 1.13
Applications and emerging trends of hyaluronic acid in tissue engineering, as a dermal filler and in osteoarthritis treatment. Acta Biomater (2013) 1.09
CD44v6 coordinates tumor matrix-triggered motility and apoptosis resistance. J Biol Chem (2011) 1.07
Proinflammatory cytokines induce hyaluronan synthesis and monocyte adhesion in human endothelial cells through hyaluronan synthase 2 (HAS2) and the nuclear factor-kappaB (NF-kappaB) pathway. J Biol Chem (2010) 1.05
Sickle red cells induce adhesion of lymphocytes and monocytes to endothelium. Blood (2008) 1.05
Layilin, a novel integral membrane protein, is a hyaluronan receptor. Mol Biol Cell (2001) 1.04
Role of hyaluronan and hyaluronan-binding proteins in lung pathobiology. Am J Physiol Lung Cell Mol Physiol (2011) 1.03
IL-1 enhances expansion, effector function, tissue localization, and memory response of antigen-specific CD8 T cells. J Exp Med (2013) 1.03
Interleukin 15 induces endothelial hyaluronan expression in vitro and promotes activated T cell extravasation through a CD44-dependent pathway in vivo. J Exp Med (1999) 0.96
Liver dysfunction after lung recruitment manoeuvres during pressure-controlled ventilation in experimental acute respiratory distress. Crit Care (2007) 0.96
Physiological contribution of CD44 as a ligand for E-Selectin during inflammatory T-cell recruitment. Am J Pathol (2011) 0.94
Distinctive properties of the hyaluronan-binding domain in the lymphatic endothelial receptor Lyve-1 and their implications for receptor function. J Biol Chem (2009) 0.93
Hyaluronan - a functional and structural sweet spot in the tissue microenvironment. Front Immunol (2015) 0.93
Differential use of chondroitin sulfate to regulate hyaluronan binding by receptor CD44 in Inflammatory and Interleukin 4-activated Macrophages. J Biol Chem (2011) 0.92
Aberrant splice variants of HAS1 (Hyaluronan Synthase 1) multimerize with and modulate normally spliced HAS1 protein: a potential mechanism promoting human cancer. J Biol Chem (2009) 0.91
CD44 increases the efficiency of distant metastasis of breast cancer. Oncotarget (2015) 0.91
Inhibition of adhesion of Plasmodium falciparum-infected erythrocytes by structurally defined hyaluronic acid dodecasaccharides. Infect Immun (2001) 0.90
Characterization of promoter elements of the human HYAL-2 gene. J Biol Chem (2005) 0.90
Idiopathic pneumonia syndrome after bone marrow transplantation: the role of pre-transplant radiation conditioning and local cytokine dysregulation in promoting lung inflammation and fibrosis. Int J Exp Pathol (2001) 0.89
A refined model for the TSG-6 link module in complex with hyaluronan: use of defined oligosaccharides to probe structure and function. J Biol Chem (2014) 0.89
Regulation of inflammatory chemokine receptors on blood T cells associated to the circulating versus liver chemokines in dengue fever. PLoS One (2012) 0.88
Interactions between CD44 and Hyaluronan in Leukocyte Trafficking. Front Immunol (2015) 0.88
CD44 and HCELL: preventing hematogenous metastasis at step 1. FEBS Lett (2011) 0.88
One-Step Multipurpose Surface Functionalization by Adhesive Catecholamine. Adv Funct Mater (2012) 0.87
A role for the endothelial glycosaminoglycan hyaluronan in neutrophil recruitment by endothelial cells cultured for prolonged periods. Exp Cell Res (2009) 0.87
Hyaluronan anchored to activated CD44 on central nervous system vascular endothelial cells promotes lymphocyte extravasation in experimental autoimmune encephalomyelitis. J Biol Chem (2012) 0.87
Hyperglycemia-Induced Changes in Hyaluronan Contribute to Impaired Skin Wound Healing in Diabetes: Review and Perspective. Int J Cell Biol (2015) 0.86
The interaction between CD44 on tumour cells and hyaluronan under physiologic flow conditions: implications for metastasis formation. Histochem Cell Biol (2012) 0.86
Molecular aspects of Plasmodium falciparum Infection during pregnancy. J Biomed Biotechnol (2007) 0.85
Matrix metalloproteinases, T cell homing and beta-cell mass in type 1 diabetes. Vitam Horm (2009) 0.85
Binding of Hyaluronan to the Native Lymphatic Vessel Endothelial Receptor LYVE-1 Is Critically Dependent on Receptor Clustering and Hyaluronan Organization. J Biol Chem (2016) 0.84
Enhanced expression of CD44 variants in human atheroma and abdominal aortic aneurysm: possible role for a feedback loop in endothelial cells. Am J Pathol (2004) 0.83
Roles of Proteoglycans and Glycosaminoglycans in Wound Healing and Fibrosis. Int J Cell Biol (2015) 0.82
Knock-down of CD44 regulates endothelial cell differentiation via NFκB-mediated chemokine production. PLoS One (2014) 0.82
Treatment with the hyaluronic Acid synthesis inhibitor 4-methylumbelliferone suppresses LPS-induced lung inflammation. Inflammation (2015) 0.81
Inhibition of HA synthase 3 mRNA expression, with a phosphodiesterase 3 inhibitor, blocks lung injury in a septic ventilated rat model. Lung (2009) 0.81
Identification of proteases employed by dendritic cells in the processing of protein purified derivative (PPD). J Immune Based Ther Vaccines (2004) 0.81
Blockade of TGF-β by catheter-based local intravascular gene delivery does not alter the in-stent neointimal response, but enhances inflammation in pig coronary arteries. Int J Cardiol (2010) 0.80
Lack of lymphatic vessel phenotype in LYVE-1/CD44 double knockout mice. J Cell Physiol (2009) 0.80
The where, when, how, and why of hyaluronan binding by immune cells. Front Immunol (2015) 0.79
Distinct kinetic and molecular requirements govern CD44 binding to hyaluronan versus fibrin(ogen). Biophys J (2012) 0.79
The role of hyaluronan in innate defense responses of the intestine. Int J Cell Biol (2015) 0.78
Acute Lung Injury Regulation by Hyaluronan. J Allergy Ther (2011) 0.78
Changes in serum hyaluronic acid levels and expression of CD44 and CD44 mRNA in hepatic sinusoidal endothelial cells after major hepatectomy in cirrhotic rats. World J Surg (2002) 0.78
IL-17 and insulin/IGF1 enhance adhesion of prostate cancer cells to vascular endothelial cells through CD44-VCAM-1 interaction. Prostate (2015) 0.77
A single molecule assay to probe monovalent and multivalent bonds between hyaluronan and its key leukocyte receptor CD44 under force. Sci Rep (2016) 0.76
A low molecular weight heparin inhibits experimental metastasis in mice independently of the endothelial glycocalyx. PLoS One (2010) 0.76
CD44 promotes the migration of bone marrow-derived mesenchymal stem cells toward glioma. Oncol Lett (2016) 0.75
Versican deficiency significantly reduces lung inflammatory response induced by polyinosine-polycytidylic acid stimulation. J Biol Chem (2016) 0.75
CD44 induced enhancement of phosphatase activity and calcium influx: Modifications of EGR-1 expression and cell proliferation. Biochem Biophys Rep (2016) 0.75
E-selectin-mediated rolling facilitates pancreatic cancer cell adhesion to hyaluronic acid. FASEB J (2017) 0.75
Traffic signals for lymphocyte recirculation and leukocyte emigration: the multistep paradigm. Cell (1994) 27.85
Analysis of enzymatically amplified beta-globin and HLA-DQ alpha DNA with allele-specific oligonucleotide probes. Nature (1986) 17.77
Leukocyte-endothelial cell recognition: three (or more) steps to specificity and diversity. Cell (1991) 13.70
Lymphocyte homing and homeostasis. Science (1996) 13.26
Leukocytes roll on a selectin at physiologic flow rates: distinction from and prerequisite for adhesion through integrins. Cell (1991) 11.89
CD44 is the principal cell surface receptor for hyaluronate. Cell (1990) 11.01
Endothelial leukocyte adhesion molecule 1: an inducible receptor for neutrophils related to complement regulatory proteins and lectins. Science (1989) 10.70
Leukocyte-endothelial adhesion molecules. Blood (1994) 8.62
Selectins and their ligands: current concepts and controversies. Blood (1996) 5.78
Mouse myelomas and lymphomas in culture. Exp Cell Res (1970) 5.12
Cytokines and endothelial cell biology. Physiol Rev (1990) 5.02
Endothelial-leukocyte adhesion molecules. Annu Rev Immunol (1993) 4.96
CD44 and its interaction with extracellular matrix. Adv Immunol (1993) 4.04
An inducible endothelial cell surface glycoprotein mediates melanoma adhesion. Science (1989) 4.01
The integrin VLA-4 supports tethering and rolling in flow on VCAM-1. J Cell Biol (1995) 3.88
Hyaluronate can function as a cell adhesion molecule and CD44 participates in hyaluronate recognition. J Exp Med (1990) 3.78
Antigen-specific development of primary and memory T cells in vivo. Science (1995) 3.41
Requirement for CD44 in activated T cell extravasation into an inflammatory site. Science (1997) 3.28
The hematopoietic and epithelial forms of CD44 are distinct polypeptides with different adhesion potentials for hyaluronate-bearing cells. EMBO J (1991) 3.20
Leukocyte adhesion molecule-1 (LAM-1, L-selectin) interacts with an inducible endothelial cell ligand to support leukocyte adhesion. J Immunol (1991) 3.05
Monoclonal antibodies to Pgp-1/CD44 block lympho-hemopoiesis in long-term bone marrow cultures. J Exp Med (1990) 3.05
Cytokine regulation of endothelial cell function. FASEB J (1992) 3.00
Neutrophils roll on E-selectin. J Immunol (1993) 2.91
CD44 and its ligand hyaluronate mediate rolling under physiologic flow: a novel lymphocyte-endothelial cell primary adhesion pathway. J Exp Med (1996) 2.37
Interaction between CD44 and hyaluronate is directly implicated in the regulation of tumor development. J Exp Med (1994) 2.37
Requirements for hyaluronic acid binding by CD44: a role for the cytoplasmic domain and activation by antibody. J Exp Med (1992) 2.30
Anti-CD44 treatment abrogates tissue oedema and leukocyte infiltration in murine arthritis. Nat Med (1995) 2.05
P-selectin mediates neutrophil rolling on histamine-stimulated endothelial cells. Biophys J (1993) 1.95
CD44 is necessary for optimal contact allergic responses but is not required for normal leukocyte extravasation. J Exp Med (1993) 1.91
E-selectin supports neutrophil rolling in vitro under conditions of flow. J Clin Invest (1993) 1.90
IL-4 increases human endothelial cell adhesiveness for T cells but not for neutrophils. J Immunol (1990) 1.86
Cytokine-regulated expression of E-selectin, intercellular adhesion molecule-1 (ICAM-1), and vascular cell adhesion molecule-1 (VCAM-1) in human microvascular endothelial cells. J Immunol (1996) 1.84
Glycosylation of CD44 negatively regulates its recognition of hyaluronan. J Exp Med (1995) 1.62
A two-step adhesion cascade for T cell/endothelial cell interactions under flow conditions. J Clin Invest (1994) 1.57
Hyaluronan binding function of CD44 is transiently activated on T cells during an in vivo immune response. J Exp Med (1994) 1.47
Turnover of hyaluronan in synovial joints: elimination of labelled hyaluronan from the knee joint of the rabbit. Exp Physiol (1991) 1.44
Expression of proteoglycans and hyaluronan during wound healing. J Histochem Cytochem (1995) 1.42
CD44 activation and associated primary adhesion is inducible via T cell receptor stimulation. J Immunol (1997) 1.40
CD44 and hyaluronan-dependent rolling interactions of lymphocytes on tonsillar stroma. J Cell Biol (1996) 1.38
Variant cell lines selected for alterations in the function of the hyaluronan receptor CD44 show differences in glycosylation. J Exp Med (1995) 1.35
Measurement of an adhesion molecule as an indicator of inflammatory disease activity. Up-regulation of the receptor for hyaluronate (CD44) in rheumatoid arthritis. Arthritis Rheum (1991) 1.35
Canine neutrophil margination mediated by lectin adhesion molecule-1 in vitro. J Immunol (1991) 1.33
Hyaluronan and the hyaluronan receptor RHAMM promote focal adhesion turnover and transient tyrosine kinase activity. J Cell Biol (1994) 1.33
Distinct cell surface ligands mediate T lymphocyte attachment and rolling on P and E selectin under physiological flow. J Cell Biol (1994) 1.31
Distribution of hyaluronate and hyaluronate receptors in the adult lung. J Cell Sci (1988) 1.31
The properties and turnover of hyaluronan. Ciba Found Symp (1986) 1.26
Circulating hyaluronic acid levels vary with physical activity in healthy subjects and in rheumatoid arthritis patients. Relationship to synovitis mass and morning stiffness. Arthritis Rheum (1987) 1.23
Hyaluronan concentration in non-inflamed and rheumatoid synovium. Br J Rheumatol (1994) 1.22
Isolation and culture of high endothelial cells from rat lymph nodes. J Cell Sci (1987) 1.22
Raised serum hyaluronate levels in scleroderma: an effect of growth factor induced activation of connective tissue cells? Ann Rheum Dis (1985) 1.20
The kinetics of hyaluronan in normal and acutely inflamed synovial joints: observations with experimental arthritis in sheep. Semin Arthritis Rheum (1993) 1.10
Hyaluronic acid-induced lymphocyte signal transduction and HA receptor (GP85/CD44)-cytoskeleton interaction. J Immunol (1993) 1.09
Dissection of murine lymphocyte-endothelial cell interaction mechanisms by SV-40-transformed mouse endothelial cell lines: novel mechanisms mediating basal binding, and alpha 4-integrin-dependent cytokine-induced adhesion. Exp Cell Res (1991) 1.04
Changes in hyaluronan concentration in tissues and body fluids in disease states. Ciba Found Symp (1989) 1.00
Beneficial actions of exogenous hyaluronic acid on wound healing. Surgery (1991) 1.00
Increased hyaluronic acid is associated with dermal delayed-type hypersensitivity. Inflammation (1982) 0.95
Studies of the modulation of MHC antigen and cell adhesion molecule expression on human dermal microvascular endothelial cells. J Invest Dermatol (1991) 0.94
Distribution of hyaluronic acid and sulfated glycosaminoglycans during blood-vessel development in the chick chorioallantoic membrane. Am J Anat (1986) 0.92
Isolation and culture of synovial microvascular endothelial cells. Characterization and assessment of adhesion molecule expression. Arthritis Rheum (1992) 0.92
Regulation of the expression of intercellular adhesion molecule 1 in cultured human endothelial cells derived from rheumatoid synovium. Arthritis Rheum (1993) 0.91
Cytokeratin expression and hyaluronic acid production in cultures of human synovial microvascular endothelial cells: influence of cytokines and growth factors. Microcirculation (1996) 0.83
High levels of hyaluronate in suction blister fluid from active psoriatic lesions. Br J Dermatol (1987) 0.83
Hyaluronan and CD44 in psoriatic skin. Intense staining for hyaluronan on dermal capillary loops and reduced expression of CD44 and hyaluronan in keratinocyte-leukocyte interfaces. Arch Dermatol Res (1994) 0.81
Circulating hyaluronate in psoriasis. Br J Dermatol (1985) 0.80
Cell surface molecule associated with lymphocyte homing is a ubiquitinated branched-chain glycoprotein. Science (1986) 3.33
Requirement for CD44 in activated T cell extravasation into an inflammatory site. Science (1997) 3.28
Novel anti-CD4 monoclonal antibodies separate human immunodeficiency virus infection and fusion of CD4+ cells from virus binding. J Exp Med (1990) 3.01
Lymphocyte homing receptors. Cell (1986) 2.70
CD44 and its ligand hyaluronate mediate rolling under physiologic flow: a novel lymphocyte-endothelial cell primary adhesion pathway. J Exp Med (1996) 2.37
Expression cloning of a lymphocyte homing receptor cDNA: ubiquitin is the reactive species. Science (1986) 2.33
The route of antigen entry determines the requirement for L-selectin during immune responses. J Exp Med (1996) 1.61
Activation and interaction of CD44 and hyaluronan in immunological systems. J Leukoc Biol (1999) 1.51
Heterogeneity of an intrastrain cross-reactive idiotype associated with anti-p-azophenylarsonate antibodies of A/J mice. J Immunol (1980) 1.51
CD44 activation and associated primary adhesion is inducible via T cell receptor stimulation. J Immunol (1997) 1.40
Sequence analysis and structure-function correlations of murine q, k, u, s, and f haplotype I-A beta cDNA clones. Proc Natl Acad Sci U S A (1986) 1.39
DNA sequence and characterization of human class II major histocompatibility complex beta chains from the DR1 haplotype. Proc Natl Acad Sci U S A (1985) 1.39
Selective requirements for leukocyte adhesion molecules in models of acute and chronic cutaneous inflammation: participation of E- and P- but not L-selectin. Blood (1999) 1.30
Detection of immunoglobulin light-chain mRNA in lymphoid tissues using a practical in situ hybridization method. Am J Pathol (1990) 1.28
The CD44-initiated pathway of T-cell extravasation uses VLA-4 but not LFA-1 for firm adhesion. J Clin Invest (2000) 1.25
Complete amino acid sequence of light chain variable regions derived from five monoclonal anti-p-azophenylarsonate antibodies differing with respect to a crossreactive idiotype. Proc Natl Acad Sci U S A (1981) 1.24
Hyaluronan anchoring and regulation on the surface of vascular endothelial cells is mediated through the functionally active form of CD44. J Biol Chem (2000) 1.19
Expression of the TAL1 proto-oncogene in cultured endothelial cells and blood vessels of the spleen. Oncogene (1993) 1.19
Adjustment of homosexual and heterosexual women. Br J Psychiatry (1972) 1.15
Somatic mutation in genes for the variable portion of the immunoglobulin heavy chain. Science (1982) 1.11
Presence of highly conserved idiotypic determinants in a family of antibodies that constitute an intrastrain cross-reactive idiotype. J Exp Med (1980) 0.99
XO-XX and XO-XY mosaicism. A study of a family. Obstet Gynecol (1972) 0.86
The relation of birth order to sexual orientation in men and women. J Biosoc Sci (1998) 0.82
Studies of genetic control and microheterogeneity of an idiotype associated with anti-P-azophenylarsonate antibodies of A/J mice. Prog Clin Biol Res (1980) 0.82
Biosynthesis pathway of gp90MEL-14, the mouse lymph node-specific homing receptor. J Immunol (1990) 0.81
Normal hematopoiesis and inflammatory responses despite discrete signaling defects in Galpha15 knockout mice. Mol Cell Biol (2000) 0.81
Adjustment of male homosexuals and heterosexuals. Arch Sex Behav (1972) 0.80
Gene rearrangements in monoclonal A/J anti-arsonate antibodies. J Immunol (1982) 0.78
Birth order and family size of homosexual men and women. J Consult Clin Psychol (1973) 0.75
The cross-reactive idiotype of A-strain mice Serological and structural analyses. Immunol Today (1982) 0.75
Parent behavior correlates of personality traits related to creativity in sons and daughters. J Consult Clin Psychol (1973) 0.75
Adjustment of homosexual and heterosexual women: a cross-national replication. Arch Sex Behav (1979) 0.75
The inability of in vitro transforming SV40 subgenomes to cause tumors in vivo. Intervirology (1984) 0.75
Primary structural analysis of monoclonal anti-p-azophenyl-arsonate antibodies. Prog Clin Biol Res (1980) 0.75
College student personality correlates of early parent-child relationship. J Consult Psychol (1965) 0.75
Parental backgrounds of homosexual and heterosexual women: a cross-national replication. Arch Sex Behav (1981) 0.75
"Origins" of extraversion-introversion. J Psychol (1968) 0.75
Psychological adjustment of homosexual and heterosexual men: a cross-national replication. Arch Sex Behav (1978) 0.75
Effect of factor XII deficiency on pregnancy and parturition. Thromb Haemost (1979) 0.75
Parental background of homosexual and heterosexual women. Br J Psychiatry (1974) 0.75
Parental background of male homosexuals and heterosexuals. Arch Sex Behav (1974) 0.75
Dimerization of CD4-C kappa chimeric molecules leads to loss of CD4 epitopes. Mol Immunol (1993) 0.75
Parental backgrounds of homosexual and heterosexual men: a cross national replication. Arch Sex Behav (1981) 0.75
Family background of alcoholics: some research considerations. Ann N Y Acad Sci (1972) 0.75