PubRank

M X Sliwkowski

Author PubWeight™ 83.87‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Untangling the ErbB signalling network. Nat Rev Mol Cell Biol 2001 28.05
2 Identification of heregulin, a specific activator of p185erbB2. Science 1992 4.17
3 Targeting cyclooxygenase 2 and HER-2/neu pathways inhibits colorectal carcinoma growth. Gastroenterology 2001 3.13
4 HER-2 tyrosine kinase pathway targets estrogen receptor and promotes hormone-independent growth in human breast cancer cells. Oncogene 1995 2.84
5 The erbB3 gene product is a receptor for heregulin. J Biol Chem 1994 2.63
6 Inhibition of HER2/neu (erbB-2) and mitogen-activated protein kinases enhances tamoxifen action against HER2-overexpressing, tamoxifen-resistant breast cancer cells. Cancer Res 2000 2.24
7 Binding specificities and affinities of egf domains for ErbB receptors. FEBS Lett 1999 2.06
8 Neuregulin-3 (NRG3): a novel neural tissue-enriched protein that binds and activates ErbB4. Proc Natl Acad Sci U S A 1997 1.89
9 Axon-induced mitogenesis of human Schwann cells involves heregulin and p185erbB2. Proc Natl Acad Sci U S A 1995 1.73
10 Identification of Gas6 as a growth factor for human Schwann cells. J Neurosci 1996 1.45
11 Biologic effects of heregulin/neu differentiation factor on normal and malignant human breast and ovarian epithelial cells. Oncogene 1999 1.39
12 The influence of heregulins on human Schwann cell proliferation. J Neurosci 1995 1.34
13 Regulation of the acetylcholine receptor epsilon subunit gene by recombinant ARIA: an in vitro model for transynaptic gene regulation. Neuron 1995 1.32
14 Growth regulation of human breast and ovarian tumor cells by heregulin: Evidence for the requirement of ErbB2 as a critical component in mediating heregulin responsiveness. Cancer Res 1996 1.25
15 Genetically engineered proinsulin constitutively processed and secreted as mature, active insulin. J Biol Chem 1994 1.19
16 Formation of a high affinity heregulin binding site using the soluble extracellular domains of ErbB2 with ErbB3 or ErbB4. FEBS Lett 1998 1.17
17 CD20: a gene in search of a function. Semin Oncol 2000 1.14
18 Overexpression of HER2/neu in solid tumours: an immunohistochemical survey. Histopathology 2001 1.13
19 A naturally occurring secreted human ErbB3 receptor isoform inhibits heregulin-stimulated activation of ErbB2, ErbB3, and ErbB4. Cancer Res 2001 1.10
20 Incorporation and distribution of selenium into thiolase from Clostridium kluyveri. J Biol Chem 1985 1.10
21 Suppression of breast cancer cell growth by a monoclonal antibody targeting cleavable ErbB4 isoforms. Oncogene 2009 1.09
22 Binding interaction of the heregulinbeta egf domain with ErbB3 and ErbB4 receptors assessed by alanine scanning mutagenesis. J Biol Chem 1998 1.03
23 Gamma-heregulin: a novel heregulin isoform that is an autocrine growth factor for the human breast cancer cell line, MDA-MB-175. Oncogene 1997 1.00
24 Biological response to ErbB ligands in nontransformed cell lines correlates with a specific pattern of receptor expression. Endocrinology 1998 0.98
25 Neuregulin-1 and human epidermal growth factor receptors 2 and 3 play a role in human lung development in vitro. Am J Respir Cell Mol Biol 2000 0.95
26 Simultaneous single-step purification of thiolase and NADP-dependent 3-hydroxybutyryl-CoA dehydrogenase from Clostridium kluyveri. Anal Biochem 1984 0.94
27 Association of csk-homologous kinase (CHK) (formerly MATK) with HER-2/ErbB-2 in breast cancer cells. J Biol Chem 1997 0.94
28 Insulin regulates heregulin binding and ErbB3 expression in rat hepatocytes. J Biol Chem 1996 0.92
29 Heregulins and the ErbB-2/3/4 receptors in gliomas. J Neurooncol 1997 0.92
30 The biology of human epidermal growth factor receptor 2. Curr Oncol Rep 1999 0.92
31 Heregulin is rapidly translocated to the nucleus and its transport is correlated with c-myc induction in breast cancer cells. Oncogene 1996 0.92
32 Purification and immunological studies of selenoprotein A of the clostridial glycine reductase complex. J Biol Chem 1987 0.91
33 High-resolution solution structure of the EGF-like domain of heregulin-alpha. Biochemistry 1996 0.90
34 Serological evaluation of Escherichia coli-expressed human T-cell leukemia virus type I env, gag p24, and tax proteins. J Clin Microbiol 1990 0.89
35 A potential role for activated HER-2 in prostate cancer. Semin Oncol 2000 0.88
36 A discrete three-amino acid segment (LVI) at the C-terminal end of kinase-impaired ErbB3 is required for transactivation of ErbB2. J Biol Chem 1999 0.85
37 Development of herceptin. Breast Dis 2000 0.84
38 Selection of heregulin variants having higher affinity for the ErbB3 receptor by monovalent phage display. J Biol Chem 1998 0.84
39 Catalytic effect of sulfhydryl oxidase on the formation of three-dimensional structure in chymotrypsinogen A. Arch Biochem Biophys 1978 0.82
40 Analysis of heregulin-induced ErbB2 phosphorylation with a high-throughput Kinase receptor activation enzyme-linked immunosorbant assay. Anal Biochem 1996 0.82
41 Nonidentity of sulfhydryl oxidase and gama-glutamyltransferase in bovine milk. Arch Biochem Biophys 1981 0.80
42 Effects of in vivo heregulin beta1 treatment in wild-type and ErbB gene-targeted mice depend on receptor levels and pregnancy. Am J Pathol 2001 0.79
43 Resolution of sulphydryl oxidase from gamma-glutamyltransferase in bovine milk by covalent chromatography on cysteinylsuccinamidopropyl-glass. Biochem J 1983 0.79
44 Backbone dynamics of the EGF-like domain of heregulin-alpha. J Mol Biol 1998 0.79
45 Kinetic mechanism and specificity of bovine milk sulphydryl oxidase. Biochem J 1984 0.77
46 Structural requirements for ErbB2 transactivation. Semin Oncol 2001 0.77
47 Establishment of Schwann cell lines from normal adult and embryonic rat dorsal root ganglia. J Neurosci Methods 1996 0.77
48 Labeling of cysteine-containing peptides with 2-nitro-5-thiobenzoic acid. Anal Biochem 1985 0.75
49 Selenomethionine-containing thiolase and 3-hydroxybutyryl-CoA dehydrogenase from Clostridium kluyveri. Curr Top Cell Regul 1985 0.75
50 Assay of enzyme-catalyzed oxygen-dependent disulfide bond formation. Methods Enzymol 1987 0.75
51 Neuregulin receptor-mediated gene transfer by human epidermal growth factor receptor 2-targeted antibodies and neuregulin-1. Cancer Gene Ther 2000 0.75
52 Characterization of selenomethionine in proteins. Methods Enzymol 1984 0.75