Published in Semin Cancer Biol on June 01, 1997
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An ABC transporter controls export of a Drosophila germ cell attractant. Science (2009) 2.02
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Bile formation and secretion. Compr Physiol (2013) 1.32
MDR1 Ala893 polymorphism is associated with inflammatory bowel disease. Am J Hum Genet (2003) 1.26
Safety of fluralaner, a novel systemic antiparasitic drug, in MDR1(-/-) Collies after oral administration. Parasit Vectors (2014) 1.25
Multidrug resistance 1 gene in inflammatory bowel disease: a meta-analysis. World J Gastroenterol (2006) 1.18
Evolutionary conservation of vertebrate blood-brain barrier chemoprotective mechanisms in Drosophila. J Neurosci (2009) 1.17
The multidrug transporter, P-glycoprotein, actively mediates cholesterol redistribution in the cell membrane. Proc Natl Acad Sci U S A (2002) 1.15
HMG-CoA reductase inhibitors and P-glycoprotein modulation. Br J Pharmacol (2001) 1.15
The mechanism of action of multidrug-resistance-linked P-glycoprotein. J Bioenerg Biomembr (2001) 1.13
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Plasma pharmacokinetic profile of fluralaner (Bravecto™) and ivermectin following concurrent administration to dogs. Parasit Vectors (2015) 1.06
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P-glycoprotein regulates blood-testis barrier dynamics via its effects on the occludin/zonula occludens 1 (ZO-1) protein complex mediated by focal adhesion kinase (FAK). Proc Natl Acad Sci U S A (2011) 1.05
MDR1 synonymous polymorphisms alter transporter specificity and protein stability in a stable epithelial monolayer. Cancer Res (2013) 1.04
MDR1 genotypes do not influence the absorption of a single oral dose of 1 mg digoxin in healthy white males. Br J Clin Pharmacol (2002) 0.99
Co-administration of GF120918 significantly increases the systemic exposure to oral paclitaxel in cancer patients. Br J Cancer (2001) 0.99
ATP-binding cassette efflux transporters in human placenta. Curr Pharm Biotechnol (2011) 0.98
Cholesterol asymmetry in synaptic plasma membranes. J Neurochem (2011) 0.96
Role of blood-brain barrier P-glycoprotein in limiting brain accumulation and sedative side-effects of asimadoline, a peripherally acting analgaesic drug. Br J Pharmacol (1999) 0.96
Polymorphism in the P-glycoprotein drug transporter MDR1 gene in colon cancer patients. Eur J Clin Pharmacol (2005) 0.96
Chemotoxicity of doxorubicin and surface expression of P-glycoprotein (MDR1) is regulated by the Pseudomonas aeruginosa toxin Cif. Am J Physiol Cell Physiol (2008) 0.94
Small molecules that dramatically alter multidrug resistance phenotype by modulating the substrate specificity of P-glycoprotein. Proc Natl Acad Sci U S A (2001) 0.93
Exploiting nanotechnology to overcome tumor drug resistance: Challenges and opportunities. Adv Drug Deliv Rev (2013) 0.92
The multidrug resistance 1 (MDR1) gene polymorphism G-rs3789243-A is not associated with disease susceptibility in Norwegian patients with colorectal adenoma and colorectal cancer; a case control study. BMC Med Genet (2009) 0.91
The effects of the cyclosporin A, a P-glycoprotein inhibitor, on the pharmacokinetics of baicalein in the rat: a microdialysis study. Br J Pharmacol (2002) 0.89
Genes that act downstream of sensory neurons to influence longevity, dauer formation, and pathogen responses in Caenorhabditis elegans. PLoS Genet (2012) 0.86
Choroid plexus transport: gene deletion studies. Fluids Barriers CNS (2011) 0.85
Managing drug-resistant epilepsy: challenges and solutions. Neuropsychiatr Dis Treat (2016) 0.85
YC-1, a novel potential anticancer agent, inhibit multidrug-resistant protein via cGMP-dependent pathway. Invest New Drugs (2010) 0.84
In silico analysis of the binding of anthelmintics to Caenorhabditis elegansP-glycoprotein 1. Int J Parasitol Drugs Drug Resist (2016) 0.83
Aβ1-42 reduces P-glycoprotein in the blood-brain barrier through RAGE-NF-κB signaling. Cell Death Dis (2014) 0.83
Gene-wide characterization of common quantitative trait loci for ABCB1 mRNA expression in normal liver tissues in the Chinese population. PLoS One (2012) 0.81
High frequency of a single nucleotide substitution (c.-6-180T>G) of the canine MDR1/ABCB1 gene associated with phenobarbital-resistant idiopathic epilepsy in Border Collie dogs. Dis Markers (2013) 0.80
Modulation of cytochrome P450 metabolism and transport across intestinal epithelial barrier by ginger biophenolics. PLoS One (2014) 0.80
Vascularisation of the central nervous system. Mech Dev (2015) 0.80
Effect of ABCB1 C3435T polymorphism on docetaxel pharmacokinetics according to menopausal status in breast cancer patients. Br J Cancer (2010) 0.79
The association between polymorphisms in the MDR1 gene and risk of cancer: a systematic review and pooled analysis of 52 case-control studies. Cancer Cell Int (2013) 0.79
P-Glycoprotein/MDR1 regulates pokemon gene transcription through p53 expression in human breast cancer cells. Int J Mol Sci (2010) 0.79
Keratinocyte growth factor-2 stimulates P-glycoprotein expression and function in intestinal epithelial cells. Am J Physiol Gastrointest Liver Physiol (2013) 0.78
Treatment of MDR1 mutant dogs with macrocyclic lactones. Curr Pharm Biotechnol (2012) 0.78
Enhanced brain disposition and effects of Δ9-tetrahydrocannabinol in P-glycoprotein and breast cancer resistance protein knockout mice. PLoS One (2012) 0.78
ABCB1 C3435T polymorphism is associated with leukemia susceptibility: evidence from a meta-analysis. Onco Targets Ther (2015) 0.78
P-glycoprotein-activity measurements in multidrug resistant cell lines: single-cell versus single-well population fluorescence methods. Biomed Res Int (2013) 0.77
Increased activity of Pgp multidrug transporter in patients with Helicobacter pylori infection. World J Gastroenterol (2005) 0.77
Lactobacillus acidophilus stimulates intestinal P-glycoprotein expression via a c-Fos/c-Jun-dependent mechanism in intestinal epithelial cells. Am J Physiol Gastrointest Liver Physiol (2016) 0.76
Genetic update on inflammatory factors in ulcerative colitis: Review of the current literature. World J Gastrointest Pathophysiol (2014) 0.76
Multidrug resistance gene 1 C1236T polymorphism and susceptibility to leukemia: A meta-analysis. Biomed Rep (2014) 0.76
ABCB1 polymorphism and susceptibility to acute lymphoblastic leukemia: a meta analysis. Int J Clin Exp Med (2015) 0.75
Low heritability in pharmacokinetics of talinolol: a pharmacogenetic twin study on the heritability of the pharmacokinetics of talinolol, a putative probe drug of MDR1 and other membrane transporters. Genome Med (2016) 0.75
Astroglial expression of the P-glycoprotein is controlled by intracellular CNTF. BMC Cell Biol (2002) 0.75
Evaluation of multidrug resistance-1 gene C>T polymorphism frequency in patients with asthma. Clinics (Sao Paulo) (2015) 0.75
Drug Interactions in Neurocritical Care. Neurocrit Care (2017) 0.75