Structure-activity analysis of the interaction of curacin A, the potent colchicine site antimitotic agent, with tubulin and effects of analogs on the growth of MCF-7 breast cancer cells.

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Published in Mol Pharmacol on January 01, 1998

Authors

P Verdier-Pinard1, J Y Lai, H D Yoo, J Yu, B Marquez, D G Nagle, M Nambu, J D White, J R Falck, W H Gerwick, B W Day, E Hamel

Author Affiliations

1: Laboratory of Drug Discovery Research and Development, National Cancer Institute, Frederick Cancer Research and Development Center, Maryland 21702, USA.

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