| Rank |
Title |
Journal |
Year |
PubWeight™‹?› |
|
1
|
Comparison of carbamazepine, phenobarbital, phenytoin, and primidone in partial and secondarily generalized tonic-clonic seizures.
|
N Engl J Med
|
1985
|
2.73
|
|
2
|
Importance of the intracellular domain of NR2 subunits for NMDA receptor function in vivo.
|
Cell
|
1998
|
2.21
|
|
3
|
Impairment of synaptic vesicle clustering and of synaptic transmission, and increased seizure propensity, in synapsin I-deficient mice.
|
Proc Natl Acad Sci U S A
|
1995
|
2.00
|
|
4
|
Autoantibodies to glutamate receptor GluR3 in Rasmussen's encephalitis.
|
Science
|
1994
|
1.98
|
|
5
|
Requirement for superoxide in excitotoxic cell death.
|
Neuron
|
1996
|
1.80
|
|
6
|
Plasmapheresis in Rasmussen's encephalitis.
|
Neurology
|
1996
|
1.65
|
|
7
|
Autoimmunity to munc-18 in Rasmussen's encephalitis.
|
Neuron
|
2000
|
1.55
|
|
8
|
Limbic epilepsy in transgenic mice carrying a Ca2+/calmodulin-dependent kinase II alpha-subunit mutation.
|
Proc Natl Acad Sci U S A
|
1995
|
1.36
|
|
9
|
Immunohistochemical evidence of seizure-induced activation of trk receptors in the mossy fiber pathway of adult rat hippocampus.
|
J Neurosci
|
1999
|
1.29
|
|
10
|
Evidence implicating substantia nigra in regulation of kindled seizure threshold.
|
J Neurosci
|
1984
|
1.28
|
|
11
|
Increased dentate granule cell neurogenesis following amygdala kindling in the adult rat.
|
Neurosci Lett
|
1998
|
1.22
|
|
12
|
Antiepileptogenic effects of conventional anticonvulsants in the kindling model of epilespy.
|
Ann Neurol
|
1991
|
1.19
|
|
13
|
Cloning and expression of a novel Na(+)-dependent neutral amino acid transporter structurally related to mammalian Na+/glutamate cotransporters.
|
J Biol Chem
|
1993
|
1.16
|
|
14
|
Synaptic connections from multiple subfields contribute to granule cell hyperexcitability in hippocampal slice cultures.
|
J Neurophysiol
|
2000
|
1.15
|
|
15
|
Excitatory amino acid receptors in epilepsy.
|
Trends Pharmacol Sci
|
1990
|
1.14
|
|
16
|
Selective inhibition of kindling development by intraventricular administration of TrkB receptor body.
|
J Neurosci
|
1999
|
1.14
|
|
17
|
Induction of c-fos mRNA by kindled seizures: complex relationship with neuronal burst firing.
|
J Neurosci
|
1993
|
1.13
|
|
18
|
Benzodiazepine receptor increases after repeated seizures: evidence for localization to dentate granule cells.
|
Proc Natl Acad Sci U S A
|
1982
|
1.11
|
|
19
|
Human genetics. Did radicals strike Lou Gehrig?
|
Nature
|
1993
|
1.10
|
|
20
|
The kindling model of epilepsy: a review.
|
Prog Neurobiol
|
1980
|
1.07
|
|
21
|
Null mutation of c-fos impairs structural and functional plasticities in the kindling model of epilepsy.
|
J Neurosci
|
1996
|
1.06
|
|
22
|
Ionotropic glutamate receptor subtypes activate c-fos transcription by distinct calcium-requiring intracellular signaling pathways.
|
Neuron
|
1993
|
1.03
|
|
23
|
Seizures, cell death, and mossy fiber sprouting in kainic acid-treated organotypic hippocampal cultures.
|
Neuroscience
|
1999
|
1.01
|
|
24
|
Evidence that Substantia Nigra is crucial to neural network of kindled seizures.
|
Eur J Pharmacol
|
1983
|
0.99
|
|
25
|
Repeated seizures induce long-term increase in hippocampal benzodiazepine receptors.
|
Proc Natl Acad Sci U S A
|
1980
|
0.99
|
|
26
|
GluR3 autoantibodies destroy neural cells in a complement-dependent manner modulated by complement regulatory proteins.
|
J Neurosci
|
2000
|
0.99
|
|
27
|
Biochemical evidence that glycine allosterically regulates an NMDA receptor-coupled ion channel.
|
Eur J Pharmacol
|
1987
|
0.98
|
|
28
|
NMDA and non-NMDA receptor-mediated increase of c-fos mRNA in dentate gyrus neurons involves calcium influx via different routes.
|
J Neurosci
|
1992
|
0.98
|
|
29
|
Seizure outcome after temporal lobectomy for temporal lobe epilepsy: a Kaplan-Meier survival analysis.
|
Neurology
|
2000
|
0.97
|
|
30
|
gamma-Aminobutyric acid and benzodiazepine receptors in the kindling model of epilepsy: a quantitative radiohistochemical study.
|
J Neurosci
|
1985
|
0.95
|
|
31
|
Arrhythmogenic epilepsy: an hypothesis.
|
Am Heart J
|
1980
|
0.95
|
|
32
|
NMDA receptor dependence of kindling and mossy fiber sprouting: evidence that the NMDA receptor regulates patterning of hippocampal circuits in the adult brain.
|
J Neurosci
|
1996
|
0.95
|
|
33
|
Centronuclear myopathy: histochemistry and electron microscopy. Report of two cases.
|
Arch Pathol
|
1975
|
0.94
|
|
34
|
A physical map across chromosome 11q22-q23 containing the major locus for ataxia telangiectasia.
|
Genomics
|
1994
|
0.93
|
|
35
|
Role of neurotransmitters in seizure mechanisms in the kindling model of epilepsy.
|
Fed Proc
|
1984
|
0.93
|
|
36
|
N-methyl-D-aspartate receptor plasticity in kindling: quantitative and qualitative alterations in the N-methyl-D-aspartate receptor-channel complex.
|
Proc Natl Acad Sci U S A
|
1989
|
0.92
|
|
37
|
Kindling model of epilepsy.
|
Adv Neurol
|
1986
|
0.91
|
|
38
|
Selective enhancement of axonal branching of cultured dentate gyrus neurons by neurotrophic factors.
|
Neuroscience
|
1995
|
0.91
|
|
39
|
Altered regulation of brain-derived neurotrophic factor protein in hippocampus following slice preparation.
|
Neuroscience
|
2004
|
0.90
|
|
40
|
Changes in dynorphin, enkephalin and cholecystokinin content of hippocampus and substantia nigra after amygdala kindling.
|
Brain Res
|
1986
|
0.89
|
|
41
|
Differential expression of immediate early genes in the hippocampus in the kindling model of epilepsy.
|
Brain Res Mol Brain Res
|
1991
|
0.89
|
|
42
|
Induction of c-fos mRNA expression by afterdischarge in the hippocampus of naive and kindled rats.
|
J Neurochem
|
1990
|
0.88
|
|
43
|
Kindling enhances sensitivity of CA3 hippocampal pyramidal cells to NMDA.
|
J Neurosci
|
1992
|
0.87
|
|
44
|
A point mutation (D79N) of the alpha2A adrenergic receptor abolishes the antiepileptogenic action of endogenous norepinephrine.
|
J Neurosci
|
1998
|
0.87
|
|
45
|
Kindling induces the long-lasting expression of a novel population of NMDA receptors in hippocampal region CA3.
|
J Neurosci
|
1994
|
0.87
|
|
46
|
Anterior temporal lobectomy for complex partial seizures: evaluation, results, and long-term follow-up in 100 cases.
|
Neurology
|
1990
|
0.86
|
|
47
|
The value of carotid endarterectomy in treating transient cerebral ischemia of the posterior circulation.
|
Neurology
|
1977
|
0.86
|
|
48
|
Seizure disorders in mutant mice: relevance to human epilepsies.
|
Curr Opin Neurobiol
|
1999
|
0.86
|
|
49
|
Anti-seizure and anti-epileptogenic effect of gamma-vinyl gamma-aminobutyric acid in amygdaloid kindling.
|
Brain Res
|
1986
|
0.85
|
|
50
|
Glycine regulation of the N-methyl-D-aspartate receptor-gated ion channel in hippocampal membranes.
|
Mol Pharmacol
|
1989
|
0.85
|
|
51
|
Glutamate receptor GluR3 antibodies and death of cortical cells.
|
Neuron
|
1998
|
0.85
|
|
52
|
Increased AMPA-sensitive quisqualate receptor binding and reduced NMDA receptor binding in epileptic human hippocampus.
|
J Neurosci
|
1991
|
0.85
|
|
53
|
Kindling: an animal model of complex partial epilepsy.
|
Ann Neurol
|
1984
|
0.84
|
|
54
|
Evidence that zinc inhibits N-methyl-D-aspartate receptor-gated ion channel activation by noncompetitive antagonism of glycine binding.
|
Mol Pharmacol
|
1990
|
0.83
|
|
55
|
Activation of substantia nigra neurons: role in the propagation of seizures in kindled rats.
|
J Neurosci
|
1986
|
0.83
|
|
56
|
N-methyl-D-aspartate receptor regulation of uncompetitive antagonist binding in rat brain membranes: kinetic analysis.
|
Mol Pharmacol
|
1988
|
0.83
|
|
57
|
Myelin basic protein phosphatase activity in rat brain.
|
J Neurochem
|
1977
|
0.83
|
|
58
|
Quantitative autoradiographic analysis of mu and delta opioid binding sites in the rat hippocampal formation.
|
J Comp Neurol
|
1986
|
0.83
|
|
59
|
Pseudoepileptic seizures: methods and video analysis to aid diagnosis.
|
Ann Neurol
|
1982
|
0.83
|
|
60
|
Differences in the anatomic distribution of immediate-early gene expression in amygdala and angular bundle kindling development.
|
J Neurosci
|
1995
|
0.82
|
|
61
|
The kindling model of epilepsy: a critical review.
|
CRC Crit Rev Clin Neurobiol
|
1985
|
0.82
|
|
62
|
Muscarinic cholinergic receptors participate in the kindling model of epilepsy.
|
Brain Res
|
1978
|
0.82
|
|
63
|
Selective alterations of regional beta-adrenergic receptor binding in the kindling model of epilepsy.
|
Exp Neurol
|
1978
|
0.82
|
|
64
|
N-methyl-D-aspartate receptors activate transcription of c-fos and NGFI-A by distinct phospholipase A2-requiring intracellular signaling pathways.
|
Mol Pharmacol
|
1995
|
0.82
|
|
65
|
Mechanism of epilepsy.
|
Annu Rev Med
|
1994
|
0.82
|
|
66
|
Autoimmunity and neurological disease: antibody modulation of synaptic transmission.
|
Annu Rev Neurosci
|
1999
|
0.82
|
|
67
|
Abnormal neuronal excitability in hippocampal slices from kindled rats.
|
J Neurophysiol
|
1985
|
0.81
|
|
68
|
Prostaglandin F2alpha is required for NMDA receptor-mediated induction of c-fos mRNA in dentate gyrus neurons.
|
J Neurosci
|
1997
|
0.81
|
|
69
|
The tyrosine receptor kinase B ligand, neurotrophin-4, is not required for either epileptogenesis or tyrosine receptor kinase B activation in the kindling model.
|
Neuroscience
|
2006
|
0.81
|
|
70
|
The gene encoding the glutamate receptor subunit GluR5 is located on human chromosome 21q21.1-22.1 in the vicinity of the gene for familial amyotrophic lateral sclerosis.
|
Proc Natl Acad Sci U S A
|
1993
|
0.81
|
|
71
|
Knife cuts of entorhinal cortex: effects on development of amygdaloid kindling and seizure-induced decrease of muscarinic cholinergic receptors.
|
J Neurosci
|
1985
|
0.80
|
|
72
|
Sustained potential shifts and paroxysmal discharges in hippocampal formation.
|
J Neurophysiol
|
1985
|
0.80
|
|
73
|
Effects of age on kindling and kindled seizure-induced increase of benzodiazepine receptor binding.
|
Brain Res
|
1986
|
0.80
|
|
74
|
Alpha-2 receptors mediate an endogenous noradrenergic suppression of kindling development.
|
J Pharmacol Exp Ther
|
1987
|
0.80
|
|
75
|
Plasmapheresis in Rasmussen's encephalitis. 1996.
|
Neurology
|
2001
|
0.79
|
|
76
|
N-methyl-D-aspartate receptor autoradiography in rat brain after angular bundle kindling.
|
Brain Res
|
1989
|
0.79
|
|
77
|
Role of the substantia nigra in the kindling model of limbic epilepsy.
|
Adv Exp Med Biol
|
1986
|
0.79
|
|
78
|
Amygdala kindling induces muscarinic cholinergic receptor declines in a highly specific distribution within the limbic system.
|
Exp Neurol
|
1980
|
0.79
|
|
79
|
Epilepsy. Protease inhibitor implicated.
|
Nature
|
1996
|
0.79
|
|
80
|
Microinjection of muscimol into entopeduncular nucleus suppresses pilocarpine but not maximal electroshock seizures in rats.
|
Brain Res
|
1988
|
0.79
|
|
81
|
Kindled seizure-induced reduction of muscarinic cholinergic receptors in rat hippocampal formation: evidence for localization to dentate granule cells.
|
J Comp Neurol
|
1983
|
0.79
|
|
82
|
Decreased density, but not number, of N-methyl-D-aspartate, glycine and phencyclidine binding sites in hippocampus of senescent rats.
|
Brain Res
|
1990
|
0.79
|
|
83
|
Kindling and associated mossy fibre sprouting are not affected in mice deficient of NGFI-A/NGFI-B genes.
|
Neuroscience
|
1998
|
0.79
|
|
84
|
When do epileptic seizures really begin?
|
Neuron
|
2001
|
0.79
|
|
85
|
Evidence implicating dentate granule cells in wet dog shakes produced by kindling stimulations of entorhinal cortex.
|
Exp Neurol
|
1986
|
0.79
|
|
86
|
A radiohistochemical measure of [3H]TCP binding to the activated NMDA-receptor-gated ion channel in rat brain.
|
Brain Res
|
1990
|
0.78
|
|
87
|
Kindling reduces sensitivity of CA3 hippocampal pyramidal cells to competitive NMDA receptor antagonists.
|
Neuropharmacology
|
1994
|
0.78
|
|
88
|
Chromosomal localization of gene for human glutamate receptor subunit-7.
|
Somat Cell Mol Genet
|
1993
|
0.78
|
|
89
|
Intranigral dynorphin-1-13 suppresses kindled seizures by a naloxone-insensitive mechanism.
|
Brain Res
|
1987
|
0.78
|
|
90
|
Activation of substantia nigra pars reticulata neurons: role in the initiation and behavioral expression of kindled seizures.
|
Brain Res
|
1991
|
0.78
|
|
91
|
Pursuit of the mechanisms of kindling.
|
Trends Neurosci
|
1988
|
0.78
|
|
92
|
Experimental partial epileptogenesis.
|
Curr Opin Neurol
|
1999
|
0.78
|
|
93
|
Immunoglobulin G and complement immunoreactivity in the cerebral cortex of patients with Rasmussen's encephalitis.
|
Neurology
|
1999
|
0.78
|
|
94
|
Interstitial ion concentrations and paroxysmal discharges in hippocampal formation and spinal cord.
|
Adv Neurol
|
1986
|
0.78
|
|
95
|
Regulation of alternative splicing of NMDAR1 in the kindling model.
|
Brain Res Mol Brain Res
|
1996
|
0.77
|
|
96
|
Intradentate colchicine retards the development of amygdala kindling.
|
Ann Neurol
|
1982
|
0.77
|
|
97
|
Effect of kindling on potassium-induced electrographic seizures in vitro.
|
Neurosci Lett
|
1989
|
0.77
|
|
98
|
Lateral entorhinal cortical kindling can be established without potentiation of the entorhinal-granule cell synapse.
|
Exp Neurol
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1984
|
0.77
|
|
99
|
Electrolytic entorhinal lesions cause seizures.
|
Brain Res
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1982
|
0.77
|
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100
|
Inhibition of muscarinic-coupled phosphoinositide hydrolysis by N-methyl-D-aspartate is dependent on depolarization via channel activation.
|
J Neurochem
|
1990
|
0.77
|
|
101
|
Selective increase in L-[3H]glutamate binding to a quisqualate-sensitive site on hippocampal synaptic membranes after angular bundle kindling.
|
Eur J Pharmacol
|
1982
|
0.77
|
|
102
|
Human hypoxia and seizures: effects and interactions.
|
Adv Neurol
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1979
|
0.77
|
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103
|
The role of substantia nigra in the development of kindling: pharmacologic and lesion studies.
|
Brain Res
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1987
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0.77
|
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104
|
Evidence implicating alpha-2 adrenergic receptors in the anticonvulsant action of intranigral muscimol.
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J Pharmacol Exp Ther
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1987
|
0.77
|
|
105
|
Measurement of NMDA receptor protein subunits in discrete hippocampal regions of kindled animals.
|
Brain Res Mol Brain Res
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1998
|
0.77
|
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106
|
Evaluation of the alpha(2A)-adrenergic receptor gene in a heritable form of temporal lobe epilepsy.
|
Neurology
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1998
|
0.77
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107
|
Kindled seizures result in decreased responsiveness of benzodiazepine receptors to gamma-aminobutyric acid (GABA).
|
J Pharmacol Exp Ther
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1983
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0.77
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108
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Biochemical evidence for enhanced sensitivity to N-methyl-D-aspartate in the hippocampal formation of kindled rats.
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Brain Res
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1989
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0.77
|
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109
|
Evidence for an agonist independent down regulation of hippocampal muscarinic receptors in kindling.
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Brain Res
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1980
|
0.76
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110
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Biochemical and radiohistochemical analyses of alpha-2 adrenergic receptors in the kindling model of epilepsy.
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J Pharmacol Exp Ther
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1990
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0.76
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111
|
Congenital ichthyosis with spastic paraplegia of adult onset.
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Arch Neurol
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1975
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0.76
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112
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Evidence implicating dentate granule cells in development of entorhinal kindling.
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Exp Neurol
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1986
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0.76
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113
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Rasmussen's encephalitis: an autoimmune disorder?
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Curr Opin Neurol
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1996
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0.76
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114
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Stargazing nets new calcium channel subunit.
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Nat Genet
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1998
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0.75
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115
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Seizures down-regulate muscarinic cholinergic receptors in hippocampal formation.
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Brain Res
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1982
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0.75
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116
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An in vitro autoradiographic analysis of mu and delta opioid binding in the hippocampal formation of kindled rats.
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Brain Res
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1987
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0.75
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117
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Effects of intranigral application of clinically-effective anticonvulsants on electroshock-induced seizures.
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Neuropharmacology
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1989
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0.75
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118
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Epilepsy and all that jazz.
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Nat Med
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2001
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0.75
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119
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Spontaneous interictal spiking in the awake kindled rat.
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Electroencephalogr Clin Neurophysiol
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1979
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0.75
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120
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Clinical and electroencephalographic correlates in Rasmussen's encephalitis.
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Emergency management of the patient with seizures. 1. Generalized status epilepticus.
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Postgrad Med
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Biochemical approaches to dementia.
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123
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Uncompetitive antagonist binding: a biochemical index of activation of the NMDA receptor-coupled ion channel.
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1992
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0.75
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124
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Reduced kainic acid binding in rat hippocampal formation after limbic kindling.
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Brain Res
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1984
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0.75
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125
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Stimulation of substantia nigra pars reticulata enhances dentate granule cell excitability.
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Brain Res
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1987
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0.75
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126
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Selective and reversible increase in the number of quisqualate-sensitive glutamate binding sites on hippocampal synaptic membranes after angular bundle kindling.
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Brain Res
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1984
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0.75
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127
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Kainate and quisqualate receptor autoradiography in rat brain after angular bundle kindling.
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Neuroscience
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1990
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0.75
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128
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Radiohistochemical demonstration of NMDA/glycine-channel activation in rat hippocampus.
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Eur J Pharmacol
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1988
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0.75
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129
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Barbiturate and GABA receptors coupled to benzodiazepine receptors in rat hippocampal formation: a radiohistochemical study.
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Life Sci
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1981
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0.75
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130
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Method of lesioning brainstem determines seizure probability.
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J Neurosci Methods
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1986
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0.75
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131
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Muscarinic cholinergic regulation of epileptic spiking in kindling.
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Brain Res
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1979
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0.75
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132
|
Complex neuronal systems: approach to development of new strategies in the treatment of epilepsy.
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Adv Neurol
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1980
|
0.75
|
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133
|
Kindling, prenatal exposure to ethanol and postnatal development selectively alter responses of hippocampal pyramidal cells to NMDA.
|
Adv Exp Med Biol
|
1990
|
0.75
|
|
134
|
Intermittent claudication due to cauda equina compression.
|
N C Med J
|
1985
|
0.75
|
|
135
|
Effects of oral choline on human complex partial seizures.
|
Neurology
|
1980
|
0.75
|
|
136
|
Kindled seizures selectively reduce a subpopulation of [3H]quinuclidinyl benzilate binding sites in rat dentate gyrus.
|
J Pharmacol Exp Ther
|
1982
|
0.75
|
|
137
|
TCP binding: a tool for studying NMDA receptor-mediated neurotransmission in kindling.
|
Neurosci Biobehav Rev
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1989
|
0.75
|
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138
|
Rasmussen's encephalitis: an autoimmune disorder?
|
Curr Opin Neurobiol
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1996
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0.75
|
|
139
|
Activity of locus coeruleus neurons in amygdala kindled rats: role in the suppression of afterdischarge.
|
Brain Res
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1987
|
0.75
|
|
140
|
Emergency management of the patient with seizures. 1. Classification and treatment system, common seizure disorders.
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Postgrad Med
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1974
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0.75
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141
|
Anticonvulsant action of intranigral gamma-vinyl-GABA: role of nonadrenergic neurotransmission.
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Brain Res
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1988
|
0.75
|
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142
|
Epilepsy.
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Proc Annu Meet Med Sect Am Counc Life Insur
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1981
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0.75
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143
|
Comparison of the effects of diphenylbarbituric acid, phenobarbital, pentobarbital and secobarbital on GABA-mediated inhibition and benzodiazepine binding.
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J Pharmacol Exp Ther
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1985
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0.75
|
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144
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Clinical relevance of defects in signalling pathways.
|
Curr Opin Neurobiol
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1995
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0.75
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145
|
Microinjection of a benzodiazepine into substantia nigra elevates kindled seizure threshold.
|
Brain Res
|
1987
|
0.75
|
|
146
|
Benzodiazepine receptor declines in hippocampal formation following limbic seizures.
|
Brain Res
|
1983
|
0.75
|
|
147
|
Autoradiographic localization of benzomorphan binding sites in rat brain.
|
Eur J Pharmacol
|
1985
|
0.75
|
|
148
|
Abnormal hyperexcitability of hippocampal slices from kindled rats is transient.
|
Brain Res
|
1988
|
0.75
|
|
149
|
Biochemical evidence of decreased muscarinic cholinergic neuronal communication following amygdala-kindled seizures.
|
Brain Res
|
1981
|
0.75
|