Published in Biochem Pharmacol on July 01, 1976
Oxygen-sensitive and -insensitive nitroreduction by Escherichia coli and rat hepatic microsomes. J Biol Chem (1979) 2.03
The metabolism of 2-fluorobenzoic acid. II. Studies with 18-O2. J Biol Chem (1968) 1.45
The role of catalytic superoxide formation in the O2 inhibition of nitroreductase. Biochem Biophys Res Commun (1975) 1.43
The mechanism of microsomal and mitochondrial nitroreductase. Electron spin resonance evidence for nitroaromatic free radical intermediates. Biochemistry (1975) 1.36
The effect of phenobarbital on the turnover of microsomal phospholipid in male and female rats. J Biol Chem (1968) 1.21
The pharmacokinetics of daunomycin in man. Clin Pharmacol Ther (1971) 1.16
Drug metabolism by rat and human hepatic microsomes in response to interaction with H2-receptor antagonists. Gastroenterology (1982) 1.15
The distribution of the components of mixed-function oxidase between the rough and the smooth endoplasmic reticulum of liver cells. Biochem J (1968) 1.12
Potentiation of acetaminophen hepatotoxicity by alcohol. JAMA (1980) 1.04
Inhibition of azoreductase by oxygen. The role of the azo anion free radical metabolite in the reduction of oxygen to superoxide. Mol Pharmacol (1978) 0.95
Induction of cytochrome CYPIA1 and formation of toxic metabolites of benzo[a]pyrene by rat aorta: a possible role in atherogenesis. Proc Natl Acad Sci U S A (1994) 0.94
Effect of influenza vaccine on warfarin anticoagulation. Clin Pharmacol Ther (1984) 0.88
The covalent binding of [14C]acetaminophen to mouse hepatic microsomal proteins: the specific binding to calreticulin and the two forms of the thiol:protein disulfide oxidoreductases. Chem Res Toxicol (1997) 0.88
The reported cDNA sequence for phospholipase C alpha encodes protein disulfide isomerase, isozyme Q-2 and not phospholipase-C. Biochem Biophys Res Commun (1993) 0.88
Effect of cholestyramine and colestipol on the absorption of phenytoin. Eur J Clin Pharmacol (1983) 0.87
Physiologic concentrations of homocysteine inhibit the human plasma GSH peroxidase that reduces organic hydroperoxides. J Lab Clin Med (2000) 0.87
Two sites of azo reduction in the monooxygenase system. Mol Pharmacol (1988) 0.87
The role of NADPH- and reduced glutathione-dependent enzymes in the norepinephrine modulation of the ATP-dependent, hepatic microsomal calcium pump: a new pathway for the noradrenergic regulation of cytosolic calcium in the hepatocyte. J Pharmacol Exp Ther (1987) 0.87
Iron species of hepatic microsomes from control and phenobarbital-treated rats. Arch Biochem Biophys (1974) 0.85
Ethanol induction of acetaminophen toxicity and metabolism. Life Sci (1980) 0.85
Studies on the N-demethylation and O-de-ethylation of ethylmorphine[6-3H] by male rat hepatic microsomes. J Pharmacol Exp Ther (1979) 0.84
The conversion of the carcinogen N-hydroxy-2-fluorenylacetamide to o-amidophenols by rat liver in vitro. An inducible enzymatic reaction. J Biol Chem (1969) 0.84
Phosphorylation of the androgen receptor by a nuclear cAMP-independent protein kinase. Biochem Biophys Res Commun (1984) 0.83
Effect of dietary orotic acid and adenine sulfate on hepatic microsomal enzymes in male and female rats. Biochem Pharmacol (1969) 0.83
Letter: Gentamicin and neuromuscular blockade. Ann Intern Med (1976) 0.83
The incorporation of 18-O into naphthalene in the enzymatic formation of 1,2-dihydronaphthalene-1,2-diol. J Biol Chem (1967) 0.81
Calibration of the oxygen polarograph by the depletion of oxygen with hypoxanthine-xanthine oxidase-catalase. Anal Chem (1976) 0.81
Drug-induced liver disease. Geriatrics (1981) 0.81
Interaction of flecainide with digoxin and propranolol. Am J Cardiol (1984) 0.81
Epidemiological study of urinary 6beta-hydroxycortisol to cortisol ratios and breast cancer risk. Cancer Epidemiol Biomarkers Prev (2001) 0.80
Resolution of (+/-)-propranolol. J Pharm Sci (1979) 0.80
Interaction between human serum albumin and alpha 1-acid glycoprotein in the binding of lidocaine to purified protein fractions and sera. J Pharmacol Exp Ther (1986) 0.80
The effects of several weeks of ethanol consumption on ethanol kinetics in normal men and women. Clin Pharmacol Ther (1985) 0.79
Within-person variability of the ratios of urinary 2-hydroxyestrone to 16alpha-hydroxyestrone in Caucasian women. Steroids (1999) 0.79
Pharmacokinetic interaction between isradipine and lovastatin in normal, female and male volunteers. J Pharmacol Exp Ther (1995) 0.79
The effect of phenobarbital on the synthesis of microsomal phospholipid in female and male rats. Biochem Biophys Res Commun (1966) 0.79
The kinetics of the aerobic reduction of nitrofurantoin by NADPH-cytochrome P-450 Ic) reductase. Mol Pharmacol (1981) 0.78
The conversion of the carcinogen N-hydroxy-2-fluorenylacetamide to o-amidophenols by rat liver in vitro. J Biol Chem (1972) 0.78
Metabolism of phenytoin by the gingiva of normal humans: the possible role of reactive metabolites of phenytoin in the initiation of gingival hyperplasia. Clin Pharmacol Ther (1996) 0.78
The formation of an azo anion free radical metabolite during the microsomal azo reduction of sulfonazo III. Biochem Biophys Res Commun (1977) 0.78
Effect of selenium and vitamin E deficiency on nitrofurantoin toxicity in the chick. J Nutr (1982) 0.78
Effect of methoxychlor administration to male rats on hepatic, microsomal iodothyronine 5'-deiodinase, form I. J Pharmacol Exp Ther (2000) 0.77
Role of substrate lipophilicity on the N-demethylation and type I binding of 3-O-alkylmorphine analogues. J Med Chem (1983) 0.77
No detectable reaction of the anion radical metabolite of nitrofurans with reduced glutathione or macro-molecules. Chem Biol Interact (1984) 0.77
Electron spin resonance evidence for a free radical intermediate in the cis-trans isomerization of furylfuramide by oxygen-sensitive nitroreductases. Mol Pharmacol (1979) 0.77
Effect of chronic phenobarbital administration on the turnover of hepatic microsomal protein. Biochem Pharmacol (1969) 0.77
Application of electron spin resonance to determination of serum drug concentrations. Clin Chem (1975) 0.77
Effects of ethanol and inhibitors on the binding and metabolism of acetaminophen and N-acetyl-p-benzoquinone imine by hepatic microsomes from control and ethanol-treated rats. Biochem Pharmacol (1990) 0.77
Drug-induced alterations in hepatic fatty acid desaturase activity. Biochem Pharmacol (1975) 0.77
The role of protein binding in drug therapy. Ration Drug Ther (1984) 0.77
Prostaglandins in luteal function. Recent Prog Horm Res (1972) 0.76
The temperature dependence of the components of the hepatic microsomal mixed-function oxidases. Arch Biochem Biophys (1972) 0.76
Studies on the effect of chronic consumption of moderate amounts of ethanol on male rat hepatic microsomal drug-metabolizing activity. Biochem Pharmacol (1985) 0.76
Cytochrome P450 catalyzed covalent binding of methoxychlor to rat hepatic, microsomal iodothyronine 5'-monodeiodinase, type I: does exposure to methoxychlor disrupt thyroid hormone metabolism? Arch Biochem Biophys (1995) 0.76
Inelastic laser light scattering and particle size of detergent-treated microsomes. Biochem Biophys Res Commun (1973) 0.76
The metabolism of phenytoin by isolated hepatocytes and hepatic microsomes from male rats. J Pharmacol Exp Ther (1982) 0.76
Catalysis of the cysteine conjugation and protein binding of acetaminophen by microsomes from a human lymphoblast line transfected with the cDNAs of various forms of human cytochrome P450. J Pharmacol Exp Ther (1997) 0.76
Adhesion-to-skin performance of a new transdermal nitroglycerin adhesive patch. Clin Ther (1989) 0.75
Kinetics and inelastic light-scattering studies of the role of phospholipids in the microsomal membrane structure. Drug Metab Dispos (1974) 0.75
The effect of cytochrome P-450 and reduced glutathione on the ATP-dependent calcium pump of hepatic microsomes from male rats. Arch Biochem Biophys (1986) 0.75
Studies on the N-demethylation and O-de-ethylation of ethylmorphine by hepatic microsomes from male rats. Drug Metab Dispos (1977) 0.75
Does cytochrome P-450 mediate the effects of norepinephrine in the hepatocyte? Drug Metab Rev (1989) 0.75
Spectrophotometric and radiometric studies on the in vivo binding of phenobarbital to hepatic microsomes. Arch Biochem Biophys (1976) 0.75
Studies comparing the kinetics of cysteine conjugation and protein binding of acetaminophen by hepatic microsomes from male mice. Biochim Biophys Acta (1997) 0.75
Determination of diphenylhydantoin in human serum by spin immunoassay. Clin Chem (1975) 0.75
Growth of rats fed chlortetracycline or an exhange resin. J Nutr (1965) 0.75
A convenient and sensitive in vitro radioassay of hepatic ethylmorphine N-demethylase. J Pharmacol Exp Ther (1973) 0.75
Deuterium and tritium isotope effects on the microsomal N-demethylation of ethylmorphine. Drug Metab Dispos (1975) 0.75
Effect of 4,4-dideuteration of reduced nicotinamide-adenine dinucleotide phosphate on the mixed function oxidases of hepatic microsomes. Biochemistry (1970) 0.75
Methodological causes of discrepancies in radioimmunoassay for digoxin in human serum. Clin Chem (1974) 0.75
The kinetics of ethylmorphine N-demethylation in isolated hepatocytes: the effect of drug transport and oxygen concentration. J Pharmacol Exp Ther (1982) 0.75
Kinetics of ethylmorphine N-demethylase at low substrate concentrations and its implications concerning the role of the stimulation of NADPH-cytochrome P-450 reductase activity in mixed-function oxidase activity. Biochem Pharmacol (1977) 0.75
Effect of phenobarbital induction, charcoal treatment and storage on the spectral binding characteristics and NADPH-cytochrome P-450 reductase activity of hepatic microsomes. Biochem Pharmacol (1990) 0.75
Clinical evaluation of a flat-plate membrane plasma exchange system. J Clin Apher (1983) 0.75
Metabolism of R-(+)-and S-(minus)-pentobarbital by hepatic microsomes from male rats. Drug Metab Dispos (1975) 0.75
In vivo enrichment of hepatic microsomes with isotopic iron. Anal Biochem (1974) 0.75
Inhibition of hepatic microsomal mixed function oxidases by D2O. Life Sci I (1970) 0.75
Evaluation of a parallel plate membrane plasma exchange system. J Clin Apher (1983) 0.75
The effect of exogenous intrauterine progesterone on the amount and prostaglandin F2alpha content of menstrual blood in dysmenorrheic women. J Reprod Med (1978) 0.75
Studies on the interaction of water with microsomal cytochrome P-450. Adv Exp Med Biol (1975) 0.75
The effect of phenobarbital, 3-methylcholanthrene, and pregnenolone-16 alpha-carbonitrile on the N-demethylation and O-de-ethylation of [6-H3]ethylmorphine. Drug Metab Dispos (1982) 0.75
Determination of serum morphine by the spin-label antibody technique. Drug Metab Dispos (1974) 0.75
The effect of NADH and low oxygen pressure on the hepatic microsomal ethylmorphine N-demethylase activity of the male rat. J Biol Chem (1983) 0.75
Evidence that casein kinase 2 phosphorylates hepatic microsomal calcium-binding proteins 1 and 2 but not 3. Biochemistry (1996) 0.75
Editorial: discrepancies in the radioimmunoassay for digoxin. JAMA (1975) 0.75