Tumor angiogenesis--a new therapeutic target in gliomas.

PubWeight™: 1.12‹?› | Rank: Top 10%

🔗 View Article (PMID 9482679)

Published in Acta Neurol Scand on January 01, 1998

Authors

E L Lund1, M Spang-Thomsen, H Skovgaard-Poulsen, P E Kristjansen

Author Affiliations

1: Institute of Molecular Pathology, University of Copenhagen, Denmark.

Articles by these authors

Prophylactic cranial irradiation for patients with small-cell lung cancer in complete remission. Prophylactic Cranial Irradiation Overview Collaborative Group. N Engl J Med (1999) 4.81

MCF7/LCC9: an antiestrogen-resistant MCF-7 variant in which acquired resistance to the steroidal antiestrogen ICI 182,780 confers an early cross-resistance to the nonsteroidal antiestrogen tamoxifen. Cancer Res (1997) 1.74

Epidermal growth factor receptor (EGFR) and EGFR mutations, function and possible role in clinical trials. Ann Oncol (1997) 1.61

Long-term storage of samples for flow cytometric DNA analysis. Cytometry (1983) 1.36

Loss of the retinoblastoma protein-related p130 protein in small cell lung carcinoma. Proc Natl Acad Sci U S A (1997) 1.23

Therapeutic synergy of TNP-470 and ionizing radiation: effects on tumor growth, vessel morphology, and angiogenesis in human glioblastoma multiforme xenografts. Clin Cancer Res (2000) 1.16

Expression of the proto-oncogenes c-met and c-kit and their ligands, hepatocyte growth factor/scatter factor and stem cell factor, in SCLC cell lines and xenografts. Br J Cancer (1993) 1.10

Inactivation of the transforming growth factor beta type II receptor in human small cell lung cancer cell lines. Br J Cancer (1999) 1.08

Coregulation of glucose uptake and vascular endothelial growth factor (VEGF) in two small-cell lung cancer (SCLC) sublines in vivo and in vitro. Neoplasia (2001) 1.06

Quantitation and gompertzian analysis of tumor growth. Breast Cancer Res Treat (1998) 1.05

Clonal heterogeneity of small-cell anaplastic carcinoma of the lung demonstrated by flow-cytometric DNA analysis. Cancer Res (1980) 1.05

Clinical and preclinical activity of 2',2'-difluorodeoxycytidine (gemcitabine). Cancer Treat Rev (1993) 1.02

Superiority of cisplatin or carboplatin in combination with teniposide and vincristine in the induction chemotherapy of small-cell lung cancer. A randomized trial with 5 years follow up. Ann Oncol (1996) 0.97

Growth curves of three human malignant tumors transplanted to nude mice. Exp Cell Biol (1980) 0.96

Effect of 17 beta-oestradiol on growth curves and flow cytometric DNA distribution of two human breast carcinomas grown in nude mice. Br J Cancer (1983) 0.95

Relationship between vessel density and expression of vascular endothelial growth factor and basic fibroblast growth factor in small cell lung cancer in vivo and in vitro. Clin Cancer Res (2000) 0.94

lacZ transduced human breast cancer xenografts as an in vivo model for the study of invasion and metastasis. Eur J Cancer (1992) 0.91

Comparison of characteristics of human small cell carcinoma of the lung in patients, in vitro and transplanted into nude mice. Acta Pathol Microbiol Immunol Scand A (1986) 0.91

Inter-experiment variation and dependence on culture conditions in assaying the chemosensitivity of human small cell lung cancer cell lines. Eur J Cancer Clin Oncol (1987) 0.90

Effect on growth and cell cycle kinetics of estradiol and tamoxifen on MCF-7 human breast cancer cells grown in vitro and in nude mice. Cancer Res (1989) 0.90

Genetic instability of cell lines derived from a single human small cell carcinoma of the lung. Eur J Cancer Clin Oncol (1985) 0.89

Growth suppression by transforming growth factor beta 1 of human small-cell lung cancer cell lines is associated with expression of the type II receptor. Br J Cancer (1994) 0.88

Expression of cadherin and NCAM in human small cell lung cancer cell lines and xenografts. Br J Cancer (1992) 0.88

Establishment and characterization of human uveal malignant melanoma xenografts in nude mice. Melanoma Res (2003) 0.87

Expression of the epidermal growth factor receptor in human small cell lung cancer cell lines. Cancer Res (1992) 0.87

In vitro invasion of small-cell lung cancer cell lines correlates with expression of epidermal growth factor receptor. Br J Cancer (1998) 0.87

The nude mouse as an in vivo model for human breast cancer invasion and metastasis. Breast Cancer Res Treat (1993) 0.87

Effect of endocrine therapy on growth of T61 human breast cancer xenografts is directly correlated to a specific down-regulation of insulin-like growth factor II (IGF-II). Eur J Cancer (1993) 0.87

Quantitative estimates of vascularity in solid tumors by non-invasive near-infrared spectroscopy. Neoplasia (2001) 0.86

Quantitative estimates of angiogenic and anti-angiogenic activity by laser Doppler flowmetry (LDF) and near infra-red spectroscopy (NIRS). Eur J Cancer (2001) 0.86

Abnormalities in structure and expression of the retinoblastoma gene in small cell lung cancer cell lines and xenografts in nude mice. Cancer Res (1990) 0.85

The cytotoxic activity of cisplatin, carboplatin and teniposide alone and combined determined on four human small cell lung cancer cell lines by the clonogenic assay. Eur J Cancer Clin Oncol (1988) 0.85

Transforming growth factor beta and cancer. Cancer Treat Rev (1995) 0.84

Expression of myc family oncoproteins in small-cell lung-cancer cell lines and xenografts. Int J Cancer (1993) 0.84

Expression of transforming growth factor beta (TGF beta) receptors and expression of TGF beta 1, TGF beta 2 and TGF beta 3 in human small cell lung cancer cell lines. Br J Cancer (1993) 0.84

Proliferation kinetics of a human malignant melanoma serially grown in nude mice. Cell Tissue Kinet (1984) 0.83

Treatment of newly diagnosed glioblastoma multiforme with carmustine, cisplatin and etoposide followed by radiotherapy. A phase II study. J Neurooncol (1999) 0.83

The T61 human breast cancer xenograft: an experimental model of estrogen therapy of breast cancer. Breast Cancer Res Treat (1996) 0.83

Chemotherapy of small cell lung cancer. Eur J Cancer (1991) 0.83

Spatial heterogeneity in tumor perfusion measured with functional computed tomography at 0.05 microliter resolution. Cancer Res (1994) 0.83

Disaggregation of human solid tumours by combined mechanical and enzymatic methods. Br J Cancer (1985) 0.82

Characterization of the T61 human breast carcinoma established in nude mice. Eur J Cancer Clin Oncol (1985) 0.82

Time until initiation of tumor growth is an effective measure of the anti-angiogenic effect of TNP-470 on human glioblastoma in nude mice. Oncol Rep (1999) 0.81

In vitro and in vivo evaluation of the indoloquinone EO-9 (NSC 382 459) against human small cell carcinoma of the lung. Eur J Cancer Clin Oncol (1989) 0.81

Prophylactic cranial irradiation and small cell lung cancer. Cancer Treat Rev (1988) 0.81

Second-line chemotherapy in small cell lung cancer. Cancer Treat Rev (1990) 0.81

Combined endocrine treatment of postmenopausal patients with advanced breast cancer. A randomized trial of tamoxifen vs. tamoxifen plus aminoglutethimide and hydrocortisone. Breast Cancer Res Treat (1986) 0.81

Detection of bone marrow relapse in patients with small cell carcinoma of the lung. Cancer (1986) 0.81

Northern and Southern blot analysis of human RNA and DNA in autopsy material. APMIS (1992) 0.80

Effect of tamoxifen on the receptor-positive T61 and the receptor-negative T60 human breast carcinomas grown in nude mice. Eur J Cancer Clin Oncol (1985) 0.80

Effect of single-dose X irradiation on the growth curves of a human malignant melanoma transplanted into nude mice. Radiat Res (1981) 0.80

Growth inhibition in response to estrogen withdrawal and tamoxifen therapy of human breast cancer xenografts evaluated by in vivo 31P magnetic resonance spectroscopy, creatine kinase activity, and apoptotic index. Cancer Res (1995) 0.80

Intratumoral pharmacokinetic analysis by 19F-magnetic resonance spectroscopy and cytostatic in vivo activity of gemcitabine (dFdC) in two small cell lung cancer xenografts. Ann Oncol (1993) 0.80

Dose-dependent effect of 17 beta-estradiol determined by growth curves and flow cytometric DNA analysis of a human breast carcinoma (T61) grown in nude mice. Exp Cell Biol (1985) 0.80

Overexpression of thrombospondin-1 reduces growth and vascular index but not perfusion in glioblastoma. Cancer Res (2002) 0.80

Expression and autoregulation of transforming growth factor beta receptor mRNA in small-cell lung cancer cell lines. Br J Cancer (1996) 0.80

Chemosensitivity of human small cell carcinoma of the lung detected by flow cytometric DNA analysis of drug-induced cell cycle perturbations in vitro. Cytometry (1986) 0.79

Antitumor activity of the two epipodophyllotoxin derivatives VP-16 and VM-26 in preclinical systems: a comparison of in vitro and in vivo drug evaluation. Cancer Chemother Pharmacol (1990) 0.79

Serum steroid levels in intact and endocrine ablated BALB/c nude mice and their intact littermates. J Steroid Biochem (1986) 0.79

Systemic chemotherapy of brain metastases from small-cell lung cancer: a review. J Clin Oncol (1992) 0.79

The effect of the two epipodophyllotoxin derivatives etoposide (VP-16) and teniposide (VM-26) on cell lines established from patients with small cell carcinoma of the lung. Cancer Chemother Pharmacol (1987) 0.79

Different energy metabolism in two human small cell lung cancer subpopulations examined by 31P magnetic resonance spectroscopy and biochemical analysis in vivo and in vitro. Cancer Res (1991) 0.78

Growth kinetics and in vivo radiosensitivity in nude mice of two subpopulations derived from a single human small cell carcinoma of the lung. Eur J Cancer Clin Oncol (1986) 0.78

Biochemical and physiological changes induced by nicotinamide in a C3H mouse mammary carcinoma and CDF1 mice. Int J Radiat Oncol Biol Phys (1992) 0.78

Interaction among two subpopulations of Ehrlich ascites tumor in vivo: evidence of a contact mediated immune response. Acta Pathol Microbiol Immunol Scand A (1987) 0.78

Interactions between three subpopulations of Ehrlich ascites tumor and a P388 murine leukemia in mixed solid tumors in immune competent mice. APMIS (1989) 0.78

In vitro evaluation of a new nitrosourea, TCNU, against human small cell lung cancer cell lines. Cancer Chemother Pharmacol (1987) 0.78

The role of mismatch repair in small-cell lung cancer cells. Eur J Cancer (2003) 0.78

Radiosensitivity of small-cell lung cancer xenografts compared with activity of c-myc, N-myc, L-myc, c-raf-1 and K-ras proto-oncogenes. Int J Cancer (1991) 0.77

A short-term in vitro test for tumour sensitivity to adriamycin based on flow cytometric DNA analysis. Br J Cancer (1983) 0.77

Clonal evolution demonstrated by flow cytometric DNA analysis of a human colonic carcinoma grown in nude mice. Exp Cell Biol (1982) 0.77

[Neovascularization of tumors. New therapeutic possibilities]. Ugeskr Laeger (1999) 0.77

Postincubation with aclarubicin reverses topoisomerase II mediated DNA cleavage, strand breaks, and cytotoxicity induced by VP-16. Invest New Drugs (1994) 0.77

Pulmonary absorption of instilled and inhaled DTPA in smokers. Clin Physiol (1990) 0.77

Early effects of radiotherapy in small cell lung cancer xenografts monitored by 31P magnetic resonance spectroscopy and biochemical analysis. Cancer Res (1990) 0.77

Steroid metabolism in the hormone dependent MCF-7 human breast carcinoma cell line and its two hormone resistant subpopulations MCF-7/LCC1 and MCF-7/LCC2. J Steroid Biochem Mol Biol (1998) 0.77

Cellular radiosensitivity of small-cell lung cancer cell lines. Int J Radiat Oncol Biol Phys (1997) 0.77

Migratory, invasive and metastatic capacity of NCAM transfected rat glioma cells. Int J Dev Neurosci (1993) 0.77

Endocrine therapy of human breast cancer grown in nude mice. Breast Cancer Res Treat (1987) 0.77

Effect of estrogen withdrawal on energy-rich phosphates and prediction of estrogen dependence monitored by in vivo 31P magnetic resonance spectroscopy of four human breast cancer xenografts. Cancer Res (1995) 0.76

Hypouricemia and urate excretion in small cell lung carcinoma patients with syndrome of inappropriate antidiuresis. Acta Oncol (1988) 0.76

Effect of NCAM-transfection on growth and invasion of a human cancer cell line. APMIS (1997) 0.76

Dissemination in athymic nude mice of lacZ transfected small cell lung cancer cells identified by X-gal staining. APMIS (1995) 0.76

Interaction between three subpopulations of Ehrlich carcinoma in mixed solid tumours in nude mice: evidence of contact domination. Br J Cancer (1994) 0.75

High value of the radiobiological parameter Dq correlates to expression of the transforming growth factor beta type II receptor in a panel of small cell lung cancer cell lines. Lung Cancer (1998) 0.75

Homozygous nu/nu mice with transplanted human malignant tumors. Am J Pathol (1976) 0.75

A dominated and resistant subpopulation causes regrowth after response to 1,3-bis(2-chloroethyl)-1-nitrosourea treatment of a heterogeneous small cell lung cancer xenograft in nude mice. Cancer Res (1994) 0.75

Effect of radiation therapy on small-cell lung cancer is reduced by ubiquinone intake. Folia Microbiol (Praha) (1998) 0.75

Comparison of clinical neurological function and CT response during chemotherapy for initial brain metastases from small cell lung cancer. Acta Neurol Scand (1994) 0.75

Mendelian analysis of a metastasis-prone substrain of BALB/c nude mice using a subcutaneously inoculated human tumour. APMIS (2006) 0.75

[False negative results in bone scintigraphy]. Ugeskr Laeger (1985) 0.75

Bone marrow examination in small cell lung cancer. Ann Intern Med (1987) 0.75

Syndrome of inappropriate antidiuresis in small-cell lung cancer. Classification and effect of tumor regression. Acta Med Scand (1987) 0.75