Upregulation of the vascular endothelial growth factor/vascular endothelial growth factor receptor system in experimental background diabetic retinopathy of the rat.

PubWeight™: 1.37‹?› | Rank: Top 10%

🔗 View Article (PMID 9519746)

Published in Diabetes on March 01, 1998

Authors

H P Hammes1, J Lin, R G Bretzel, M Brownlee, G Breier

Author Affiliations

1: III Medical Department, Internal Medicine, Justus-Liebig University, Giessen, Germany. hans-peter.hammes@innere.med.uni-giessen.de

Articles citing this

Vascular endothelial growth factor in eye disease. Prog Retin Eye Res (2008) 2.73

Experimental diabetes causes breakdown of the blood-retina barrier by a mechanism involving tyrosine nitration and increases in expression of vascular endothelial growth factor and urokinase plasminogen activator receptor. Am J Pathol (2003) 1.76

Single periocular injection of celecoxib-PLGA microparticles inhibits diabetes-induced elevations in retinal PGE2, VEGF, and vascular leakage. Invest Ophthalmol Vis Sci (2006) 1.52

High glucose promotes retinal endothelial cell migration through activation of Src, PI3K/Akt1/eNOS, and ERKs. Am J Physiol Cell Physiol (2008) 1.41

Intravitreal triamcinolone acetonide inhibits breakdown of the blood-retinal barrier through differential regulation of VEGF-A and its receptors in early diabetic rat retinas. Diabetes (2008) 1.39

Genetic difference in susceptibility to the blood-retina barrier breakdown in diabetes and oxygen-induced retinopathy. Am J Pathol (2005) 1.33

Spare the rod and spoil the eye. Br J Ophthalmol (2005) 1.28

The absence of diabetic retinopathy in patients with retinitis pigmentosa: implications for pathophysiology and possible treatment. Br J Ophthalmol (2001) 1.23

Whole genome assessment of the retinal response to diabetes reveals a progressive neurovascular inflammatory response. BMC Med Genomics (2008) 1.23

Inhibition of platelet-derived growth factor promotes pericyte loss and angiogenesis in ischemic retinopathy. Am J Pathol (2004) 1.18

Transforming growth factor beta1 induction of vascular endothelial growth factor receptor 1: mechanism of pericyte-induced vascular survival in vivo. Proc Natl Acad Sci U S A (2003) 1.03

Molecular mechanisms of diabetic vascular complications. J Diabetes Investig (2010) 1.01

Pharmacologic manipulation of sphingosine kinase in retinal endothelial cells: implications for angiogenic ocular diseases. Invest Ophthalmol Vis Sci (2006) 0.99

Vasoregression linked to neuronal damage in the rat with defect of polycystin-2. PLoS One (2009) 0.93

Ablation of 4E-BP1/2 prevents hyperglycemia-mediated induction of VEGF expression in the rodent retina and in Muller cells in culture. Diabetes (2010) 0.93

RPE barrier breakdown in diabetic retinopathy: seeing is believing. J Ocul Biol Dis Infor (2011) 0.92

In vitro Therapeutic Effects of Low Level Laser at mRNA Level on the Release of Skin Growth Factors from Fibroblasts in Diabetic Mice. Avicenna J Med Biotechnol (2014) 0.92

Diabetes changes expression of genes related to glutamate neurotransmission and transport in the Long-Evans rat retina. Mol Vis (2013) 0.87

Age-related alterations in retinal neurovascular and inflammatory transcripts. Mol Vis (2011) 0.85

Reduction of experimental diabetic vascular leakage by delivery of angiostatin with a recombinant adeno-associated virus vector. Mol Vis (2007) 0.85

Involvement of the Rho/Rho kinase signaling pathway in platelet-derived growth factor BB-induced vascular endothelial growth factor expression in diabetic rat retina. Jpn J Ophthalmol (2007) 0.83

MicroRNA-152 represses VEGF and TGFβ1 expressions through post-transcriptional inhibition of (Pro)renin receptor in human retinal endothelial cells. Mol Vis (2015) 0.83

Blockade of vascular endothelial growth factor receptor 1 prevents inflammation and vascular leakage in diabetic retinopathy. J Ophthalmol (2015) 0.83

Modulation of VEGF-induced retinal vascular permeability by peroxisome proliferator-activated receptor-β/δ. Invest Ophthalmol Vis Sci (2014) 0.82

Increased intraretinal PO2 in short-term diabetic rats. Diabetes (2014) 0.81

ERK5 Contributes to VEGF Alteration in Diabetic Retinopathy. J Ophthalmol (2010) 0.80

More sugar, less blood vessels: another piece in the puzzle of increased cardiovascular risk in diabetes. Arterioscler Thromb Vasc Biol (2008) 0.80

Pazopanib, a multitargeted tyrosine kinase inhibitor, reduces diabetic retinal vascular leukostasis and leakage. Microvasc Res (2011) 0.79

Role of matrix metalloproteinase-2 and -9 in the development of diabetic retinopathy. J Ocul Biol Dis Infor (2012) 0.79

Mechanisms of Hypoxic Up-Regulation of Versican Gene Expression in Macrophages. PLoS One (2015) 0.77

Pre-B cell colony enhancing factor (PBEF/NAMPT/Visfatin) and vascular endothelial growth factor (VEGF) cooperate to increase the permeability of the human placental amnion. Placenta (2012) 0.77

Administration of pigment epithelium-derived factor delivered by adeno-associated virus inhibits blood-retinal barrier breakdown in diabetic rats. Mol Vis (2010) 0.76

The MicroRNA-21 signaling pathway is involved in prorenin receptor (PRR) -induced VEGF expression in ARPE-19 cells under a hyperglycemic condition. Mol Vis (2017) 0.75

Treadmill Exercise Training Improves Vascular Endothelial Growth Factor Expression in the Cardiac Muscle of Type I Diabetic Rats. Cardiol Res (2014) 0.75

Accelerated degradation of collagen membranes in diabetic rats is associated with increased infiltration of macrophages and blood vessels. Clin Oral Investig (2015) 0.75

The expression of the Slit-Robo signal in the retina of diabetic rats and the vitreous or fibrovascular retinal membranes of patients with proliferative diabetic retinopathy. PLoS One (2017) 0.75

Articles by these authors

(truncated to the top 100)

Effects of diet and exercise in preventing NIDDM in people with impaired glucose tolerance. The Da Qing IGT and Diabetes Study. Diabetes Care (1997) 23.95

Genome sequence of enterohaemorrhagic Escherichia coli O157:H7. Nature (2001) 23.49

Abnormal blood vessel development and lethality in embryos lacking a single VEGF allele. Nature (1996) 18.47

Normalizing mitochondrial superoxide production blocks three pathways of hyperglycaemic damage. Nature (2000) 12.33

Vascular endothelial growth factor is a potential tumour angiogenesis factor in human gliomas in vivo. Nature (1992) 10.10

The adipocyte-secreted protein Acrp30 enhances hepatic insulin action. Nat Med (2001) 9.68

ATM phosphorylates p95/nbs1 in an S-phase checkpoint pathway. Nature (2000) 5.55

The nucleotide sequence of the cloned rpoD gene for the RNA polymerase sigma subunit from E coli K12. Nucleic Acids Res (1981) 5.52

Crystal structure of TFIID TATA-box binding protein. Nature (1992) 4.85

Cytokine stimulation of energy expenditure through p38 MAP kinase activation of PPARgamma coactivator-1. Mol Cell (2001) 4.58

Obesity-related glomerulopathy: an emerging epidemic. Kidney Int (2001) 3.98

Hypoxia-induced transcriptional activation and increased mRNA stability of vascular endothelial growth factor in C6 glioma cells. J Biol Chem (1995) 3.69

The vascular endothelial growth factor receptor Flt-1 mediates biological activities. Implications for a functional role of placenta growth factor in monocyte activation and chemotaxis. J Biol Chem (1996) 3.53

Hyperglycemia inhibits endothelial nitric oxide synthase activity by posttranslational modification at the Akt site. J Clin Invest (2001) 3.46

An induced proximity model for NF-kappa B activation in the Nod1/RICK and RIP signaling pathways. J Biol Chem (2000) 3.44

Hyperglycemia-induced mitochondrial superoxide overproduction activates the hexosamine pathway and induces plasminogen activator inhibitor-1 expression by increasing Sp1 glycosylation. Proc Natl Acad Sci U S A (2000) 3.36

Aminoguanidine prevents diabetes-induced arterial wall protein cross-linking. Science (1986) 3.36

Regulation of vascular endothelial growth factor expression in cultured keratinocytes. Implications for normal and impaired wound healing. J Biol Chem (1995) 3.30

Nonenzymatic glycosylation and the pathogenesis of diabetic complications. Ann Intern Med (1984) 3.14

Phenotypic diversity and ecosystem functioning in changing environments: a theoretical framework. Proc Natl Acad Sci U S A (2001) 3.13

The stationary-phase sigma factor sigma S (RpoS) is required for a sustained acid tolerance response in virulent Salmonella typhimurium. Mol Microbiol (1995) 3.11

Apolipoprotein(a) gene accounts for greater than 90% of the variation in plasma lipoprotein(a) concentrations. J Clin Invest (1992) 3.05

Lysosome biogenesis requires Rab9 function and receptor recycling from endosomes to the trans-Golgi network. J Cell Biol (1994) 2.95

Oncogenic H-ras stimulates tumor angiogenesis by two distinct pathways. Proc Natl Acad Sci U S A (1997) 2.88

Signal transduction by the TCR for antigen. Curr Opin Immunol (2000) 2.87

Cachectin/TNF and IL-1 induced by glucose-modified proteins: role in normal tissue remodeling. Science (1988) 2.87

mdm-2 inhibits the G1 arrest and apoptosis functions of the p53 tumor suppressor protein. Mol Cell Biol (1996) 2.78

Both lumenal and cytosolic gating of the aqueous ER translocon pore are regulated from inside the ribosome during membrane protein integration. Cell (1997) 2.71

Vascular endothelial growth factor induces endothelial fenestrations in vitro. J Cell Biol (1998) 2.71

The dynamics of cocirculating influenza strains conferring partial cross-immunity. J Math Biol (1997) 2.69

A role in B cell activation for CD22 and the protein tyrosine phosphatase SHP. Science (1995) 2.68

Structural analysis of a set of proteins resulting from a bacterial genomics project. Proteins (2005) 2.59

Role of tissue factor in embryonic blood vessel development. Nature (1996) 2.54

Induction of differentiation in human promyelocytic HL-60 leukemia cells activates p21, WAF1/CIP1, expression in the absence of p53. Oncogene (1994) 2.47

Regulation of transcription functions of the p53 tumor suppressor by the mdm-2 oncogene. Mol Med (1995) 2.44

Shotgun optical maps of the whole Escherichia coli O157:H7 genome. Genome Res (2001) 2.43

Competitive binding of alpha-actinin and calmodulin to the NMDA receptor. Nature (1997) 2.41

Up-regulation of vascular endothelial growth factor and its cognate receptors in a rat glioma model of tumor angiogenesis. Cancer Res (1993) 2.39

Leptin induces mitochondrial superoxide production and monocyte chemoattractant protein-1 expression in aortic endothelial cells by increasing fatty acid oxidation via protein kinase A. J Biol Chem (2001) 2.30

Epstein-Barr virus nuclear protein 3C modulates transcription through interaction with the sequence-specific DNA-binding protein J kappa. J Virol (1995) 2.25

Inhibition of constitutively active Stat3 suppresses growth of human ovarian and breast cancer cells. Oncogene (2001) 2.25

Vascular endothelial growth factor and glioma angiogenesis: coordinate induction of VEGF receptors, distribution of VEGF protein and possible in vivo regulatory mechanisms. Int J Cancer (1994) 2.24

Up-regulation of vascular endothelial growth factor and its receptors in von Hippel-Lindau disease-associated and sporadic hemangioblastomas. Cancer Res (1995) 2.23

PartsList: a web-based system for dynamically ranking protein folds based on disparate attributes, including whole-genome expression and interaction information. Nucleic Acids Res (2001) 2.23

Vasopressin administration facilitates fluid removal during hemodialysis. Kidney Int (2006) 2.23

Regulation of the pancreatic pro-endocrine gene neurogenin3. Diabetes (2001) 2.19

Aminoguanidine treatment inhibits the development of experimental diabetic retinopathy. Proc Natl Acad Sci U S A (1991) 2.12

High-affinity-receptor-mediated uptake and degradation of glucose-modified proteins: a potential mechanism for the removal of senescent macromolecules. Proc Natl Acad Sci U S A (1985) 2.11

Completely diverted tube ileostomy compared with loop ileostomy for protection of low colorectal anastomosis: a pilot study. Colorectal Dis (2014) 2.06

Beyond synexpression relationships: local clustering of time-shifted and inverted gene expression profiles identifies new, biologically relevant interactions. J Mol Biol (2001) 2.03

An oral vaccine against NMDAR1 with efficacy in experimental stroke and epilepsy. Science (2000) 2.03

Evaluation of three hollow-fiber membrane oxygenators without integrated arterial filters for neonatal cardiopulmonary bypass. Perfusion (2011) 2.02

Thromboprophylaxis rates in US medical centers: success or failure? J Thromb Haemost (2007) 2.02

Ribose facilitates thallium-201 redistribution in patients with coronary artery disease. J Nucl Med (1991) 2.00

Prevalence of diabetes mellitus secondary to pancreatic diseases (type 3c). Diabetes Metab Res Rev (2012) 2.00

Glucose and diabetic vascular disease. FASEB J (1992) 2.00

Subcutaneous injection of a cyclic peptide antagonist of vitronectin receptor-type integrins inhibits retinal neovascularization. Nat Med (1996) 1.99

The amino-terminal domains of Epstein-Barr virus nuclear proteins 3A, 3B, and 3C interact with RBPJ(kappa). J Virol (1996) 1.97

Injecting drug use and HIV infection in southwest China. AIDS (1994) 1.91

Overexpression of glyoxalase-I in bovine endothelial cells inhibits intracellular advanced glycation endproduct formation and prevents hyperglycemia-induced increases in macromolecular endocytosis. J Clin Invest (1998) 1.90

The cotranslational integration of membrane proteins into the phospholipid bilayer is a multistep process. Cell (1996) 1.88

Hemoglobin desaturation after succinylcholine-induced apnea: a study of the recovery of spontaneous ventilation in healthy volunteers. Anesthesiology (2001) 1.84

Free radical generation by early glycation products: a mechanism for accelerated atherogenesis in diabetes. Biochem Biophys Res Commun (1990) 1.80

Mild hypothermia via selective head cooling as neuroprotective therapy in term neonates with perinatal asphyxia: an experience from a single neonatal intensive care unit. J Perinatol (2006) 1.79

An adenoviral vector deleted for all viral coding sequences results in enhanced safety and extended expression of a leptin transgene. Proc Natl Acad Sci U S A (1998) 1.76

The cellular and molecular mechanisms of diabetic complications. Endocrinol Metab Clin North Am (1996) 1.73

Mitochondrial COII sequences and modern human origins. Mol Biol Evol (1993) 1.73

Identification of vascular endothelial growth factor (VEGF) receptor-2 (Flk-1) promoter/enhancer sequences sufficient for angioblast and endothelial cell-specific transcription in transgenic mice. Blood (1999) 1.73

Still embedded together binding to membranes regulates Bcl-2 protein interactions. Oncogene (2010) 1.72

Up-regulation of vascular endothelial growth factor expression in a rat glioma is conferred by two distinct hypoxia-driven mechanisms. Cancer Res (1997) 1.70

The missing link: a single unifying mechanism for diabetic complications. Kidney Int Suppl (2000) 1.69

Hyperinsulinemia enhances transcriptional activity of nuclear factor-kappaB induced by angiotensin II, hyperglycemia, and advanced glycosylation end products in vascular smooth muscle cells. Circ Res (2000) 1.69

Essential role for p53-mediated transcription in E1A-induced apoptosis. Genes Dev (1995) 1.69

The biochemistry of the complications of diabetes mellitus. Annu Rev Biochem (1981) 1.66

US of soft-tissue foreign bodies and associated complications with surgical correlation. Radiographics (2001) 1.66

Incompatibility between human blood and isolated islets of Langerhans: a finding with implications for clinical intraportal islet transplantation? Diabetes (1999) 1.65

Nonenzymatic glycosylation in vitro and in bovine endothelial cells alters basic fibroblast growth factor activity. A model for intracellular glycosylation in diabetes. J Clin Invest (1994) 1.63

A TRP homolog in Saccharomyces cerevisiae forms an intracellular Ca(2+)-permeable channel in the yeast vacuolar membrane. Proc Natl Acad Sci U S A (2001) 1.63

Constitutive activation of stat 3 oncogene product in human ovarian carcinoma cells. Gynecol Oncol (2000) 1.61

Significant progress in porcine islet mass isolation utilizing liberase HI for enzymatic low-temperature pancreas digestion. Transplantation (1999) 1.59

Mutations of the flavin-containing monooxygenase gene (FMO3) cause trimethylaminuria, a defect in detoxication. Hum Mol Genet (1998) 1.58

Genomewide scan for prostate cancer-aggressiveness loci. Am J Hum Genet (2000) 1.57

Functional neuroanatomy of spatial working memory in children. Dev Psychol (2000) 1.57

Renal aspergilloma: an unusual cause of infection in a patient with the acquired immunodeficiency syndrome. Am J Med (1992) 1.56

Death as a complication of peripherally inserted central catheters in neonates. J Pediatr (2001) 1.56

Retinoic acid inhibits induction of c-Jun protein by ultraviolet radiation that occurs subsequent to activation of mitogen-activated protein kinase pathways in human skin in vivo. J Clin Invest (1998) 1.55

Medium for Screening Leuconostoc oenos Strains Defective in Malolactic Fermentation. Appl Environ Microbiol (1989) 1.54

Hsa-miR-9 methylation status is associated with cancer development and metastatic recurrence in patients with clear cell renal cell carcinoma. Oncogene (2010) 1.53

Pessimism correlates with leukocyte telomere shortness and elevated interleukin-6 in post-menopausal women. Brain Behav Immun (2008) 1.53

Osteopenia in HIV-infected women prior to highly active antiretroviral therapy. J Infect (2003) 1.52

A genome screen of multiplex sibships with prostate cancer. Am J Hum Genet (2000) 1.51

Myocardial injury and left ventricular performance after subarachnoid hemorrhage. Stroke (1999) 1.51

Oral folate enhances endothelial function in hyperhomocysteinaemic subjects. Eur J Clin Invest (1999) 1.51

Change in failure stress on the southern san andreas fault system caused by the 1992 magnitude = 7.4 landers earthquake. Science (1992) 1.51

African Americans and participation in clinical trials: differences in beliefs and attitudes by gender. Contemp Clin Trials (2006) 1.51

Percutaneous trans-hepatic cholangioscopy and lithotripsy in the treatment of intrahepatic stones: a study with 5 year follow-up. Gastrointest Endosc (1995) 1.50

Incidence and temporal pattern of hospital readmissions for patients with atrial fibrillation. Curr Med Res Opin (2009) 1.50

Covalent attachment of soluble proteins by nonenzymatically glycosylated collagen. Role in the in situ formation of immune complexes. J Exp Med (1983) 1.49

Faecal tumour M2 pyruvate kinase: a new, sensitive screening tool for colorectal cancer. Br J Cancer (2004) 1.48

Elevated phosphorylation and activation of PDK-1/AKT pathway in human breast cancer. Br J Cancer (2005) 1.48