Published in Methods Enzymol on January 01, 1998
The small heat shock protein Hsp27 affects assembly dynamics and structure of keratin intermediate filament networks. Biophys J (2013) 0.93
Withaferin A induces proteasome inhibition, endoplasmic reticulum stress, the heat shock response and acquisition of thermotolerance. PLoS One (2012) 0.85
Small heat shock proteins prevent aggregation of citrate synthase and bind to the N-terminal region which is absent in thermostable forms of citrate synthase. Extremophiles (2007) 0.80
Proteasome inhibition induces hsp30 and hsp70 gene expression as well as the acquisition of thermotolerance in Xenopus laevis A6 cells. Cell Stress Chaperones (2009) 0.78
MAPKAP kinase 2 is essential for LPS-induced TNF-alpha biosynthesis. Nat Cell Biol (1999) 5.75
Small heat shock proteins are molecular chaperones. J Biol Chem (1993) 5.62
The p38 MAP kinase pathway signals for cytokine-induced mRNA stabilization via MAP kinase-activated protein kinase 2 and an AU-rich region-targeted mechanism. EMBO J (1999) 5.47
Crystal structures of two Sm protein complexes and their implications for the assembly of the spliceosomal snRNPs. Cell (1999) 4.57
Identification of MAPKAP kinase 2 as a major enzyme responsible for the phosphorylation of the small mammalian heat shock proteins. FEBS Lett (1992) 3.07
Binding of non-native protein to Hsp25 during heat shock creates a reservoir of folding intermediates for reactivation. EMBO J (1997) 2.92
Regulation of Hsp27 oligomerization, chaperone function, and protective activity against oxidative stress/tumor necrosis factor alpha by phosphorylation. J Biol Chem (1999) 2.85
Leptomycin B-sensitive nuclear export of MAPKAP kinase 2 is regulated by phosphorylation. EMBO J (1998) 2.82
Hsp26: a temperature-regulated chaperone. EMBO J (1999) 2.51
Interleukin-10 targets p38 MAPK to modulate ARE-dependent TNF mRNA translation and limit intestinal pathology. EMBO J (2001) 1.93
Analysis of chaperone function using citrate synthase as nonnative substrate protein. Methods Enzymol (1998) 1.84
cDNA sequence coding for a translationally controlled human tumor protein. Nucleic Acids Res (1989) 1.83
Structure and assembly of the spliceosomal small nuclear ribonucleoprotein particles. Curr Opin Struct Biol (1999) 1.79
CREB is activated by UVC through a p38/HOG-1-dependent protein kinase. EMBO J (1997) 1.78
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Stress-induced phosphorylation of STAT1 at Ser727 requires p38 mitogen-activated protein kinase whereas IFN-gamma uses a different signaling pathway. Proc Natl Acad Sci U S A (1999) 1.72
3pK, a novel mitogen-activated protein (MAP) kinase-activated protein kinase, is targeted by three MAP kinase pathways. Mol Cell Biol (1996) 1.63
Constitutive activation of mitogen-activated protein kinase-activated protein kinase 2 by mutation of phosphorylation sites and an A-helix motif. J Biol Chem (1995) 1.62
MAPKAP kinase 2 phosphorylates serum response factor in vitro and in vivo. J Biol Chem (1999) 1.58
p38 mitogen activated protein kinase regulates endothelial VCAM-1 expression at the post-transcriptional level. Biochem Biophys Res Commun (1997) 1.42
The growth-related protein P23 of the Ehrlich ascites tumor: translational control, cloning and primary structure. Biochem Int (1989) 1.33
Crystal structure of the actin-binding region of utrophin reveals a head-to-tail dimer. Structure (1999) 1.24
Alpha A-crystallin confers cellular thermoresistance. FEBS Lett (1994) 1.23
The dynamics of Hsp25 quaternary structure. Structure and function of different oligomeric species. J Biol Chem (1999) 1.20
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The MAP kinase-activated protein kinase 2 contains a proline-rich SH3-binding domain. FEBS Lett (1993) 1.19
Inactivation of protein-tyrosine phosphatases as mechanism of UV-induced signal transduction. J Biol Chem (1999) 1.16
Small heat-shock protein family: function in health and disease. Ann N Y Acad Sci (1998) 1.15
Stress-induced stimulation of early growth response gene-1 by p38/stress-activated protein kinase 2 is mediated by a cAMP-responsive promoter element in a MAPKAP kinase 2-independent manner. J Biol Chem (1999) 1.14
Structure and assembly of the spliceosomal snRNPs. Novartis Medal Lecture. Biochem Soc Trans (2001) 1.11
Abnormal migration phenotype of mitogen-activated protein kinase-activated protein kinase 2-/- neutrophils in Zigmond chambers containing formyl-methionyl-leucyl-phenylalanine gradients. J Immunol (2001) 1.09
Supramolecular structure of the recombinant murine small heat shock protein hsp25. FEBS Lett (1991) 1.05
Hypo-osmotic cell swelling activates the p38 MAP kinase signalling cascade. FEBS Lett (1996) 1.05
Stress induced gene expression: a direct role for MAPKAP kinases in transcriptional activation of immediate early genes. Nucleic Acids Res (2010) 1.04
TLR7 ligand prevents allergen-induced airway hyperresponsiveness and eosinophilia in allergic asthma by a MYD88-dependent and MK2-independent pathway. Am J Physiol Lung Cell Mol Physiol (2005) 1.02
MAPKAP kinase 2 is activated by heat shock and TNF-alpha: in vivo phosphorylation of small heat shock protein results from stimulation of the MAP kinase cascade. J Cell Biochem (1995) 1.01
PMA-induced activation of the p42/44ERK- and p38RK-MAP kinase cascades in HL-60 cells is PKC dependent but not essential for differentiation to the macrophage-like phenotype. J Cell Physiol (1997) 1.01
Development and tissue-specific distribution of mouse small heat shock protein hsp25. Dev Genet (1993) 1.01
FRET-based detection of different conformations of MK2. EMBO Rep (2001) 0.99
Heat shock protein 27 is a substrate of cGMP-dependent protein kinase in intact human platelets: phosphorylation-induced actin polymerization caused by HSP27 mutants. J Biol Chem (2001) 0.99
The electric potential profile across the erythrocyte membrane. J Theor Biol (1982) 0.96
Characterization of the proline-rich region of mouse MAPKAP kinase 2: influence on catalytic properties and binding to the c-abl SH3 domain in vitro. Biochem Biophys Res Commun (1994) 0.95
Mouse Hsp25, a small shock protein. The role of its C-terminal extension in oligomerization and chaperone action. Eur J Biochem (2000) 0.94
Over-expression of the small heat-shock protein, hsp25, inhibits growth of Ehrlich ascites tumor cells. FEBS Lett (1992) 0.94
Thiol/disulfide exchange between small heat shock protein 25 and glutathione. Biochim Biophys Acta (1998) 0.91
The effect of the intersubunit disulfide bond on the structural and functional properties of the small heat shock protein Hsp25. Int J Biol Macromol (1998) 0.91
Increased expression of heat-shock protein 27 kDa in Alzheimer disease: a preliminary study. Neuroreport (1993) 0.90
Analysis of the role of Hsp25 phosphorylation reveals the importance of the oligomerization state of this small heat shock protein in its protective function against TNFalpha- and hydrogen peroxide-induced cell death. J Cell Biochem (1998) 0.89
Comparison of the homologous carboxy-terminal domain and tail of alpha-crystallin and small heat shock protein. Mol Biol Rep (1993) 0.89
Purification of Hsp90 partner proteins Hop/p60, p23, and FKBP52. Methods Enzymol (1998) 0.88
Preoperative treatment of rectal cancer with radiation, chemotherapy and hyperthermia: analysis of treatment efficacy and heat-shock response. Radiat Res (1999) 0.87
The 5'-untranslated region of p23 mRNA from the Ehrlich ascites tumor is involved in translation control of the growth related protein p23. Biomed Biochim Acta (1991) 0.87
Deficiency of MAPK-activated protein kinase 2 (MK2) prevents adverse remodelling and promotes endothelial healing after arterial injury. Thromb Haemost (2014) 0.85
1H NMR spectroscopy reveals that mouse Hsp25 has a flexible C-terminal extension of 18 amino acids. FEBS Lett (1995) 0.85
Analysis of chaperone properties of small Hsp's. Methods Mol Biol (2000) 0.84
Dimer structure as a minimum cooperative subunit of small heat-shock proteins. Biochim Biophys Acta (1995) 0.84
Bispecific antibody-producing hybrid hybridomas selected by a fluorescence activated cell sorter. J Immunol Methods (1987) 0.84
Structural and functional homology between periplasmic bacterial molecular chaperones and small heat shock proteins. FEMS Immunol Med Microbiol (1995) 0.83
Phosphorylation is not essential for protection of L929 cells by Hsp25 against H2O2-mediated disruption actin cytoskeleton, a protection which appears related to the redox change mediated by Hsp25. Cell Stress Chaperones (1998) 0.83
Purification and characterization of prokaryotic and eukaryotic Hsp90. Methods Enzymol (1998) 0.83
Adenosine increases calcium sensitivity via receptor-independent activation of the p38/MK2 pathway in mesenteric arteries. Acta Physiol (Oxf) (2007) 0.83
Molecular cloning and characterization of the primary structure of the alkane hydroxylating cytochrome P-450 from the yeast Candida maltosa. Biochem Biophys Res Commun (1989) 0.82
The single-ring Thermoanaerobacter brockii chaperonin 60 (Tbr-EL7) dimerizes to Tbr-EL14.Tbr-ES7 under protein folding conditions. Biochemistry (1995) 0.82
p38/SAPK2-dependent gene expression in Jurkat T cells. Biol Chem (2000) 0.81
Analysis of small Hsp phosphorylation. Methods Mol Biol (2000) 0.80
Evidence for a hsp25-specific mechanism involved in transcriptional activation by heat shock. Exp Cell Res (1998) 0.80
Simple preparative two-step purification of interleukin-2 from culture medium of lectin stimulated normal human lymphocytes. J Immunol Methods (1986) 0.79
S. cerevisiae and sulfur: a unique way to deal with the environment. FASEB J (1997) 0.79
Noradrenaline enhances angiotensin II responses via p38 MAPK activation after hypoxia/re-oxygenation in renal interlobar arteries. Acta Physiol (Oxf) (2015) 0.78
Generation of antibodies against human hsp27 and murine hsp25 by immunization with a chimeric small heat shock protein. Biomed Biochim Acta (1991) 0.77
Retracted Interleukin-3 and granulocyte-macrophage colony-stimulating factor induce activation of the MAPKAP kinase 2 resulting in in vitro serine phosphorylation of the small heat shock protein (Hsp 27). Blood (1994) 0.76
The anti-cancer drug cisplatin induces H25 in Ehrlich ascites tumor cells by a mechanism different from transcriptional stimulation influencing predominantly H25 translation. Int J Cancer (1996) 0.76
Expression of heat shock protein 25,000 in rat uterus during pregnancy and pseudopregnancy. Biol Reprod (1996) 0.76
The electric potential across the erythrocyte membrane: a mathematical model. Acta Biol Med Ger (1981) 0.75
The influence of Ca2+ on the lateral lipid distribution and phase transition in phosphatidylethanolamine/phosphatidylserine vesicles. Biochim Biophys Acta (1984) 0.75
Use of fluorescence-activated cell sorting to select hybrid hybridomas producing bispecific monoclonal antibodies. Haematol Blood Transfus (1987) 0.75
Production and characterization of four monoclonal antibodies specific for human interferon-alpha-1 and -alpha-2. Biomed Biochim Acta (1989) 0.75
A theoretical approach to cluster formation in biological membranes. Biosystems (1984) 0.75
The protein kinase inhibitor SB203580 uncouples PMA-induced differentiation of HL-60 cells from phosphorylation of Hsp27. Cell Stress Chaperones (1997) 0.75
Lateral lipid distribution and phase transition in phosphatidylethanolamine/phosphatidylserine vesicles. A cross-linking study. Biochim Biophys Acta (1983) 0.75