Published in Biochim Biophys Acta on April 22, 1998
Fatty acid-binding proteins: role in metabolic diseases and potential as drug targets. Nat Rev Drug Discov (2008) 5.78
Lack of macrophage fatty-acid-binding protein aP2 protects mice deficient in apolipoprotein E against atherosclerosis. Nat Med (2001) 5.74
Selective cooperation between fatty acid binding proteins and peroxisome proliferator-activated receptors in regulating transcription. Mol Cell Biol (2002) 2.58
Fatty acid binding proteins--the evolutionary crossroads of inflammatory and metabolic responses. J Nutr (2004) 2.00
Adipocyte fatty acid-binding protein, aP2, alters late atherosclerotic lesion formation in severe hypercholesterolemia. Arterioscler Thromb Vasc Biol (2002) 1.94
Structural basis for activation of fatty acid-binding protein 4. J Mol Biol (2007) 1.52
Mammalian triacylglycerol metabolism: synthesis, lipolysis, and signaling. Chem Rev (2011) 1.28
Fatty Acid-Binding Protein 4 (FABP4): Pathophysiological Insights and Potent Clinical Biomarker of Metabolic and Cardiovascular Diseases. Clin Med Insights Cardiol (2015) 1.19
Metabolic syndrome and insulin resistance: underlying causes and modification by exercise training. Compr Physiol (2013) 1.17
Heart-type fatty acid-binding protein is essential for efficient brown adipose tissue fatty acid oxidation and cold tolerance. J Biol Chem (2010) 1.11
Functional analysis of peroxisome-proliferator-responsive element motifs in genes of fatty acid-binding proteins. Biochem J (2004) 1.09
Uterocalin, a lipocalin provisioning the preattachment equine conceptus: fatty acid and retinol binding properties, and structural characterization. Biochem J (2001) 0.99
Elevated circulating adipocyte-fatty acid binding protein levels predict incident cardiovascular events in a community-based cohort: a 12-year prospective study. J Am Heart Assoc (2013) 0.97
Pathways of polyunsaturated fatty acid utilization: implications for brain function in neuropsychiatric health and disease. Brain Res (2014) 0.94
Transcriptome survey of the anhydrobiotic tardigrade Milnesium tardigradum in comparison with Hypsibius dujardini and Richtersius coronifer. BMC Genomics (2010) 0.93
Serum liver fatty acid binding protein levels correlate positively with obesity and insulin resistance in Chinese young adults. PLoS One (2012) 0.92
Enterocyte fatty acid-binding proteins (FABPs): different functions of liver and intestinal FABPs in the intestine. Prostaglandins Leukot Essent Fatty Acids (2014) 0.91
Uncoupling lipid metabolism from inflammation through fatty acid binding protein-dependent expression of UCP2. Mol Cell Biol (2015) 0.91
Gestational diabetes mellitus causes changes in the concentrations of adipocyte fatty acid-binding protein and other adipocytokines in cord blood. Diabetes Care (2011) 0.91
Fatty acid induced remodeling within the human liver fatty acid-binding protein. J Biol Chem (2011) 0.89
FABP4 dynamics in obesity: discrepancies in adipose tissue and liver expression regarding circulating plasma levels. PLoS One (2012) 0.88
Association of serum adipocyte-specific Fatty Acid binding protein with Fatty liver index as a predictive indicator of nonalcoholic Fatty liver disease. Endocrinol Metab (Seoul) (2013) 0.86
The structure and NO binding properties of the nitrophorin-like heme-binding protein from Arabidopsis thaliana gene locus At1g79260.1. Proteins (2010) 0.86
Localization of epidermal-type fatty acid binding protein in macrophages in advanced atretic follicles of adult mice. J Mol Histol (2006) 0.84
Serum adipocyte fatty acid-binding protein levels are associated with nonalcoholic fatty liver disease in type 2 diabetic patients. Diabetes Care (2008) 0.84
Expression of epidermal fatty acid binding protein (E-FABP) in septoclasts in the growth plate cartilage of mice. J Mol Histol (2014) 0.83
The Mediterranean diet: effects on proteins that mediate fatty acid metabolism in the colon. Nutr Rev (2011) 0.82
Fatty acid signalling in a mouse enteroendocrine cell line involves fatty acid aggregates rather than free fatty acids. J Physiol (2002) 0.81
Hepatic fat accumulation and regulation of FAT/CD36: an effect of hepatic irradiation. Int J Clin Exp Pathol (2014) 0.81
Localization of brain-type fatty acid-binding protein in Kupffer cells of mice and its transient decrease in response to lipopolysaccharide. Histochem Cell Biol (2003) 0.80
Recent insights into the biological functions of liver fatty acid binding protein 1. J Lipid Res (2015) 0.79
The Antiobesity Effect of Polygonum aviculare L. Ethanol Extract in High-Fat Diet-Induced Obese Mice. Evid Based Complement Alternat Med (2013) 0.79
The polyprotein and FAR lipid binding proteins of nematodes: shape and monomer/dimer states in ligand-free and bound forms. Eur Biophys J (2003) 0.78
Unique mode of lipogenic activation in rat preputial sebocytes. J Nutr Metab (2011) 0.78
Macrophage Apoptosis and Efferocytosis in the Pathogenesis of Atherosclerosis. Circ J (2016) 0.77
Serum A-FABP is increased and closely associated with elevated NT-proBNP levels in type 2 diabetic patients treated with rosiglitazone. PLoS One (2011) 0.77
FABP3 protein promotes α-synuclein oligomerization associated with 1-methyl-1,2,3,6-tetrahydropiridine-induced neurotoxicity. J Biol Chem (2014) 0.77
Neurophysiologic measures of auditory function in fish consumers: associations with long chain polyunsaturated fatty acids and methylmercury. Neurotoxicology (2012) 0.77
Autocrine secretion of 15d-PGJ2 mediates simvastatin-induced apoptotic burst in human metastatic melanoma cells. Br J Pharmacol (2014) 0.77
Localization of fatty acid binding protein of epidermal type common to dendritic cells and presumptive macrophages in Peyer's patches and epithelial M cells of mouse intestine. Histochem Cell Biol (2009) 0.77
Specific localization of epidermal-type fatty acid binding protein in dendritic cells of splenic white pulp. Histochem Cell Biol (2003) 0.76
Positive regulations of adipogenesis by Italian ryegrass [Lolium multiflorum] in 3T3-L1 cells. BMC Biotechnol (2014) 0.76
Structure of the human-heart fatty-acid-binding protein 3 in complex with the fluorescent probe 1-anilinonaphthalene-8-sulphonic acid. J Synchrotron Radiat (2013) 0.76
Inflammatory profile in LRRK2-associated prodromal and clinical PD. J Neuroinflammation (2016) 0.76
Subcutaneous Construction of Engineered Adipose Tissue with Fat Lobule-Like Structure Using Injectable Poly-Benzyl-L-Glutamate Microspheres Loaded with Adipose-Derived Stem Cells. PLoS One (2015) 0.75
Clinical significance of elevated serum A-FABP and free fatty acid in neonates with hypoxic ischemic brain damage. Exp Ther Med (2016) 0.75
The two sides of a lipid-protein story. Biophys Rev (2016) 0.75
Genetics and molecular biology: a role for adipocyte lipid-binding protein in atherosclerosis. Curr Opin Lipidol (2002) 0.75
Identification of KMU-3, a novel derivative of gallic acid, as an inhibitor of adipogenesis. PLoS One (2014) 0.75
Fatty acid-binding protein 5 function in hepatocellular carcinoma through induction of epithelial-mesenchymal transition. Cancer Med (2017) 0.75
Knockdown of lncRNA MIR31HG inhibits adipocyte differentiation of human adipose-derived stem cells via histone modification of FABP4. Sci Rep (2017) 0.75
Adipocyte fatty acid binding protein during refeeding of female patients with anorexia nervosa. Eur J Nutr (2009) 0.75
Expression of specific mRNAs during adipose differentiation: identification of an mRNA encoding a homologue of myelin P2 protein. Proc Natl Acad Sci U S A (1984) 2.98
Evidence for an increase in transcription of specific mRNAs during differentiation of 3T3-L1 preadipocytes. J Biol Chem (1985) 2.75
Lipid-binding proteins: a family of fatty acid and retinoid transport proteins. Adv Protein Chem (1994) 2.53
The mammalian fatty acid-binding protein multigene family: molecular and genetic insights into function. Trends Endocrinol Metab (2000) 2.13
Targeted disruption of the adipocyte lipid-binding protein (aP2 protein) gene impairs fat cell lipolysis and increases cellular fatty acid levels. J Lipid Res (1999) 1.99
The up-and-down beta-barrel proteins. FASEB J (1994) 1.77
Tissue specific expression of p422 protein, a putative lipid carrier, in mouse adipocytes. Biochem Biophys Res Commun (1985) 1.66
Human adipocyte lipid-binding protein: purification of the protein and cloning of its complementary DNA. Biochemistry (1989) 1.32
The adipocyte lipid-binding protein at 1.6-A resolution. Crystal structures of the apoprotein and with bound saturated and unsaturated fatty acids. J Biol Chem (1993) 1.31
Identification of a functional peroxisome proliferator-responsive element in the murine fatty acid transport protein gene. J Biol Chem (1999) 1.29
Lipid-binding proteins modulate ligand-dependent trans-activation by peroxisome proliferator-activated receptors and localize to the nucleus as well as the cytoplasm. J Lipid Res (2000) 1.28
Interaction of rat hormone-sensitive lipase with adipocyte lipid-binding protein. Proc Natl Acad Sci U S A (1999) 1.26
Mouse fatty acid transport protein 4 (FATP4): characterization of the gene and functional assessment as a very long chain acyl-CoA synthetase. Gene (2001) 1.24
Surface properties of adipocyte lipid-binding protein: Response to lipid binding, and comparison with homologous proteins. Proteins (1998) 1.22
The fatty acid transport protein (FATP1) is a very long chain acyl-CoA synthetase. J Biol Chem (1999) 1.22
A simple assay for intracellular lipid-binding proteins using displacement of 1-anilinonaphthalene 8-sulfonic acid. Anal Biochem (1996) 1.18
Characterization of the functional interaction of adipocyte lipid-binding protein with hormone-sensitive lipase. J Biol Chem (2001) 1.17
Adipocyte lipid-binding protein complexed with arachidonic acid. Titration calorimetry and X-ray crystallographic studies. J Biol Chem (1994) 1.14
Purification of murine adipocyte lipid-binding protein. Characterization as a fatty acid- and retinoic acid-binding protein. J Biol Chem (1988) 1.13
X-ray crystallographic structures of adipocyte lipid-binding protein complexed with palmitate and hexadecanesulfonic acid. Properties of cavity binding sites. Biochemistry (1994) 1.10
Cloning, sequencing and chromosomal assignment of a gene from Saccharomyces cerevisiae which is negatively regulated by glucose and positively by lipids. Gene (1990) 1.09
Crystal structure of recombinant murine adipocyte lipid-binding protein. Biochemistry (1992) 1.05
Reaction of Bacillus subtilis glutamine phosphoribosylpyrophosphate amidotransferase with oxygen: chemistry and regulation by ligands. Biochemistry (1981) 1.03
Regulation of Bacillus subtilis glutamine phosphoribosylpyrophosphate amidotransferase inactivation in vivo. J Bacteriol (1983) 1.03
Expression, purification, and crystallization of the adipocyte lipid binding protein. J Biol Chem (1991) 1.03
Biochemical and crystallographic analyses of a portal mutant of the adipocyte lipid-binding protein. J Biol Chem (1997) 1.01
Synthesis of phosphotyrosine-containing peptides and their use as substrates for protein tyrosine phosphatases. Biochemistry (1993) 1.00
Intracellular fatty acid trafficking and the role of cytosolic lipid binding proteins. Prog Lipid Res (1989) 0.98
Modulation of ligand binding affinity of the adipocyte lipid-binding protein by selective mutation. Analysis in vitro and in situ. J Biol Chem (1993) 0.98
Structural and functional characterization of the phosphorylated adipocyte lipid-binding protein (pp15). Biochemistry (1992) 0.97
Biochemical and biophysical analysis of the intracellular lipid binding proteins of adipocytes. Mol Cell Biochem (1999) 0.97
The molecular basis for inhibition of adipose conversion of murine 3T3-L1 cells by retinoic acid. Differentiation (1990) 0.96
Purification and properties of glutamine phosphoribosylpyrophosphate amidotransferase from Bacillus subtilis. Biochemistry (1981) 0.93
Regulation of adipocyte gene expression by polyunsaturated fatty acids. Mol Cell Biochem (1998) 0.92
Fatty acid transporters in animal cells. Front Biosci (1997) 0.90
Mechanism of fluorescent fatty acid transfer from adipocyte fatty acid binding protein to membranes. Biochemistry (1993) 0.90
In vitro phosphorylation of the adipocyte lipid-binding protein (p15) by the insulin receptor. Effects of fatty acid on receptor kinase and substrate phosphorylation. J Biol Chem (1991) 0.89
Surface lysine residues modulate the collisional transfer of fatty acid from adipocyte fatty acid binding protein to membranes. Biochemistry (1995) 0.87
Expression, purification, and ligand-binding analysis of recombinant keratinocyte lipid-binding protein (MAL-1), an intracellular lipid-binding found overexpressed in neoplastic skin cells. Biochemistry (1996) 0.87
Regulation of fatty acid transporters in mammalian cells. Prog Lipid Res (2000) 0.87
Identification of the adipocyte acid phosphatase as a PAO-sensitive tyrosyl phosphatase. Protein Sci (1992) 0.86
Upregulation of bone morphogenetic protein GDF-3/Vgr-2 expression in adipose tissue of FABP4/aP2 null mice. Cytokine (2001) 0.85
Analysis of a series of phenylalanine 57 mutants of the adipocyte lipid-binding protein. Biochemistry (1998) 0.84
Adenovirus-mediated gene transfer in primary murine adipocytes. J Lipid Res (2000) 0.84
Regulation of transcription factor mRNA accumulation during 3T3-L1 preadipocyte differentiation by antagonists of adipogenesis. Mol Cell Biochem (1993) 0.83
Analysis of the ACP1 gene product: classification as an FMN phosphatase. Biochem Biophys Res Commun (1992) 0.83
Regulation of the murine adipocyte fatty acid transporter gene by insulin. Mol Endocrinol (1996) 0.82
In situ labeling of the adipocyte lipid binding protein with 3-[125I]iodo-4-azido-N-hexadecylsalicylamide. Evidence for a role of fatty acid binding proteins in lipid uptake. J Biol Chem (1990) 0.82
Cloning of murine adipocyte lipid binding protein in Escherichia coli. Its purification, ligand binding properties, and phosphorylation by the adipocyte insulin receptor. J Biol Chem (1989) 0.81
Characterization of the murine fatty acid transport protein gene and its insulin response sequence. J Biol Chem (1998) 0.81
Fatty acid binding sites of rodent adipocyte and heart fatty acid binding proteins: characterization using fluorescent fatty acids. Biochemistry (1990) 0.78
Fatty acid uptake in diabetic rat adipocytes. Mol Cell Biochem (1997) 0.77
Modification of the adipocyte lipid binding protein by sulfhydryl reagents and analysis of the fatty acid binding domain. Biochemistry (1990) 0.77
Purification of adipocyte lipid-binding protein from human and murine cells. Methods Enzymol (1990) 0.76
The purification and characterization of a fatty acid binding protein specific to pig (Sus domesticus) adipose tissue. Biochem J (1990) 0.75
Cloning and chromosomal location of the murine keratinocyte lipid-binding protein gene. Gene (1998) 0.75
In vitro association of the phosphatidylinositol 3-kinase regulatory subunit (p85) with the human insulin receptor. Int J Pept Protein Res (1995) 0.75
Identification of a class of Saccharomyces cerevisiae mutants defective in fatty acid repression of gene transcription and analysis of the frm2 gene. Yeast (1996) 0.75
In situ binding of fatty acids to the liver fatty acid binding protein: analysis using 3-[125I]iodo-4-azido-N-hexadecylsalicylamide. Biochem Biophys Res Commun (1991) 0.75
Chemical phosphorylation of proteins by zinc-ATP. Biochem Biophys Res Commun (1989) 0.75
Inactivation of glutamine: 5-phosphoribosyl 1-pyrophosphate amidotransferase in Bacillus subtilis: oxidation of an essential Fe-S centre precedes selective degradation. Biochem Soc Trans (1982) 0.75