F R Kramer

Author PubWeight™ 113.37‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Molecular beacons: probes that fluoresce upon hybridization. Nat Biotechnol 1996 21.49
2 Multicolor molecular beacons for allele discrimination. Nat Biotechnol 1998 9.40
3 Structure-independent nucleotide sequence analysis. Proc Natl Acad Sci U S A 1979 8.65
4 Molecular beacon sequence analysis for detecting drug resistance in Mycobacterium tuberculosis. Nat Biotechnol 1998 6.59
5 Detection of rifampin resistance in Mycobacterium tuberculosis in a single tube with molecular beacons. J Clin Microbiol 2001 4.89
6 Thermodynamic basis of the enhanced specificity of structured DNA probes. Proc Natl Acad Sci U S A 1999 4.46
7 Differential expression of 10 sigma factor genes in Mycobacterium tuberculosis. Mol Microbiol 1999 4.27
8 Genotypic analysis of Mycobacterium tuberculosis in two distinct populations using molecular beacons: implications for rapid susceptibility testing. Antimicrob Agents Chemother 2000 3.56
9 Autocatalytic replication of a recombinant RNA. J Mol Biol 1983 3.55
10 Multiplex detection of four pathogenic retroviruses using molecular beacons. Proc Natl Acad Sci U S A 1999 3.10
11 Multiplex detection of single-nucleotide variations using molecular beacons. Genet Anal 1999 2.99
12 Spectral genotyping of human alleles. Science 1998 2.95
13 RNA sequencing with radioactive chain-terminating ribonucleotides. Proc Natl Acad Sci U S A 1978 2.67
14 Molecular beacon probes combined with amplification by NASBA enable homogeneous, real-time detection of RNA. Nucleic Acids Res 1998 2.53
15 Novel, ligation-dependent PCR assay for detection of hepatitis C in serum. J Clin Microbiol 1996 2.19
16 Template-determined, variable rate of RNA chain elongation. Cell 1978 2.02
17 Transcription from bacteriophage T7 and SP6 RNA polymerase promoters in the presence of 3'-deoxyribonucleoside 5'-triphosphate chain terminators. Biochemistry 1985 1.88
18 Wavelength-shifting molecular beacons. Nat Biotechnol 2000 1.87
19 Complete nucleotide sequence of a replicating RNA molecule. Science 1973 1.78
20 A replicating RNA molecule suitable for a detailed analysis of extracellular evolution and replication. Proc Natl Acad Sci U S A 1972 1.55
21 Evolution in vitro: sequence and phenotype of a mutant RNA resistant to ethidium bromide. J Mol Biol 1974 1.51
22 Molecular epidemiologic evaluation of transmissibility and virulence of Mycobacterium tuberculosis. J Clin Microbiol 1999 1.43
23 Secondary structure formation during RNA synthesis. Nucleic Acids Res 1981 1.33
24 Genomic function during the lampbrush chromosome stage of amphibian oogenesis. Proc Natl Acad Sci U S A 1966 1.28
25 Terminal adenylation in the synthesis of RNA by Q beta replicase. J Biol Chem 1983 1.18
26 Extremely sensitive, background-free gene detection using binary probes and beta replicase. Proc Natl Acad Sci U S A 1996 1.15
27 N-methyl-D-aspartic acid receptor expression in the dorsolateral prefrontal cortex of elderly patients with schizophrenia. Am J Psychiatry 2001 1.08
28 Quantitative assays based on the use of replicatable hybridization probes. Clin Chem 1989 1.06
29 Synthesis of an amplifiable reporter RNA for bioassays. Nucleic Acids Res 1986 1.06
30 Evolution of the RNA coliphages: the role of secondary structures during RNA replication. Cold Spring Harb Symp Quant Biol 1987 1.06
31 Localization of the Q beta replicase recognition site in MDV-1 RNA. J Biochem 1983 0.98
32 Messenger RNA release from ribosomes during 5'-translational blockage by consecutive low-usage arginine but not leucine codons in Escherichia coli. Mol Microbiol 1997 0.97
33 RNA replication: required intermediates and the dissociation of template, product, and Q beta replicase. Biochemistry 1979 0.95
34 Modification of cytidines in a Q beta replicase template: analysis of conformation and localization of lethal nucleotide substitutions. Biochemistry 1980 0.94
35 A DNA damage signal is required for p53 to activate gadd45. Cancer Res 2000 0.92
36 Oligonucleotide arrays: new concepts and possibilities. Biotechnology (N Y) 1994 0.91
37 Amplifiable messenger RNA. Proc Natl Acad Sci U S A 1992 0.88
38 Nucleotide sequence of microvariant RNA: another small replicating molecule. Proc Natl Acad Sci U S A 1975 0.87
39 Exponential amplification of nucleic acids: new diagnostics using DNA polymerases and RNA replicases. Trends Biotechnol 1991 0.85
40 Sequencing of pools of nucleic acids on oligonucleotide arrays. Biosystems 1993 0.81
41 Comparison of pausing during transcription and replication. Nucleic Acids Res 1985 0.77
42 Coupled replication-translation of amplifiable messenger RNA. A cell-free protein synthesis system that mimics viral infection. J Biol Chem 1994 0.75
43 Amplifiable hybridization probes containing a molecular switch. Mol Cell Probes 1997 0.75