| Rank |
Title |
Journal |
Year |
PubWeight™‹?› |
|
1
|
Osteoprotegerin ligand is a cytokine that regulates osteoclast differentiation and activation.
|
Cell
|
1998
|
17.76
|
|
2
|
Osteoprotegerin: a novel secreted protein involved in the regulation of bone density.
|
Cell
|
1997
|
15.96
|
|
3
|
OPGL is a key regulator of osteoclastogenesis, lymphocyte development and lymph-node organogenesis.
|
Nature
|
1999
|
12.32
|
|
4
|
osteoprotegerin-deficient mice develop early onset osteoporosis and arterial calcification.
|
Genes Dev
|
1998
|
7.81
|
|
5
|
TRAF6 deficiency results in osteopetrosis and defective interleukin-1, CD40, and LPS signaling.
|
Genes Dev
|
1999
|
6.93
|
|
6
|
Tumor necrosis factor receptor family member RANK mediates osteoclast differentiation and activation induced by osteoprotegerin ligand.
|
Proc Natl Acad Sci U S A
|
1999
|
5.78
|
|
7
|
RANK is the intrinsic hematopoietic cell surface receptor that controls osteoclastogenesis and regulation of bone mass and calcium metabolism.
|
Proc Natl Acad Sci U S A
|
2000
|
3.95
|
|
8
|
The roles of osteoprotegerin and osteoprotegerin ligand in the paracrine regulation of bone resorption.
|
J Bone Miner Res
|
2000
|
3.38
|
|
9
|
The ligand for osteoprotegerin (OPGL) directly activates mature osteoclasts.
|
J Cell Biol
|
1999
|
2.78
|
|
10
|
Stimulation of osteoprotegerin ligand and inhibition of osteoprotegerin production by glucocorticoids in human osteoblastic lineage cells: potential paracrine mechanisms of glucocorticoid-induced osteoporosis.
|
Endocrinology
|
1999
|
2.69
|
|
11
|
Interleukin-1beta and tumor necrosis factor-alpha, but not interleukin-6, stimulate osteoprotegerin ligand gene expression in human osteoblastic cells.
|
Bone
|
1999
|
2.69
|
|
12
|
Estrogen stimulates gene expression and protein production of osteoprotegerin in human osteoblastic cells.
|
Endocrinology
|
1999
|
2.27
|
|
13
|
Osteoprotegerin reverses osteoporosis by inhibiting endosteal osteoclasts and prevents vascular calcification by blocking a process resembling osteoclastogenesis.
|
J Exp Med
|
2000
|
2.20
|
|
14
|
Osteoprotegerin inhibits the development of osteolytic bone disease in multiple myeloma.
|
Blood
|
2001
|
1.83
|
|
15
|
The effect of a single dose of osteoprotegerin in postmenopausal women.
|
J Bone Miner Res
|
2001
|
1.57
|
|
16
|
Bone morphogenetic protein 2 (BMP-2) enhances BMP-3, BMP-4, and bone cell differentiation marker gene expression during the induction of mineralized bone matrix formation in cultures of fetal rat calvarial osteoblasts.
|
Calcif Tissue Int
|
1997
|
1.51
|
|
17
|
A chimeric form of osteoprotegerin inhibits hypercalcemia and bone resorption induced by IL-1beta, TNF-alpha, PTH, PTHrP, and 1, 25(OH)2D3.
|
J Bone Miner Res
|
1999
|
1.47
|
|
18
|
Osteoprotegerin inhibits osteolysis and decreases skeletal tumor burden in syngeneic and nude mouse models of experimental bone metastasis.
|
Cancer Res
|
2001
|
1.44
|
|
19
|
The expression of osteoprotegerin and RANK ligand and the support of osteoclast formation by stromal-osteoblast lineage cells is developmentally regulated.
|
Endocrinology
|
2000
|
1.43
|
|
20
|
OPG and PTH-(1-34) have additive effects on bone density and mechanical strength in osteopenic ovariectomized rats.
|
Endocrinology
|
2001
|
1.41
|
|
21
|
Measurement of bone in the os calcis: a clinical evaluation.
|
J Bone Miner Res
|
1989
|
1.39
|
|
22
|
Difficult airway alert.
|
Anaesthesia
|
2003
|
1.38
|
|
23
|
Osteoprotegerin production by human osteoblast lineage cells is stimulated by vitamin D, bone morphogenetic protein-2, and cytokines.
|
Biochem Biophys Res Commun
|
1998
|
1.33
|
|
24
|
E-cadherin expression in human breast cancer cells suppresses the development of osteolytic bone metastases in an experimental metastasis model.
|
Cancer Res
|
1996
|
1.30
|
|
25
|
The ratio of circulating osteoprotegerin to RANKL in early rheumatoid arthritis predicts later joint destruction.
|
Arthritis Rheum
|
2006
|
1.25
|
|
26
|
Quantitative bone histology: a new method.
|
Pathology
|
1980
|
1.15
|
|
27
|
Bone resorption caused by three periodontal pathogens in vivo in mice is mediated in part by prostaglandin.
|
Infect Immun
|
1998
|
1.14
|
|
28
|
Osteoprotegerin and osteoprotegerin ligand effects on osteoclast formation from human peripheral blood mononuclear cell precursors.
|
J Cell Biochem
|
1999
|
1.07
|
|
29
|
Osteoprotegerin prevents and reverses hypercalcemia in a murine model of humoral hypercalcemia of malignancy.
|
Cancer Res
|
2000
|
1.03
|
|
30
|
Serum osteoprotegerin levels are increased in patients with advanced prostate cancer.
|
Clin Cancer Res
|
2001
|
1.03
|
|
31
|
Recovery from steroid-induced osteoporosis.
|
Ann Intern Med
|
1987
|
1.01
|
|
32
|
Immobilisation hypercalcemia.
|
Miner Electrolyte Metab
|
1984
|
0.97
|
|
33
|
Bone loss after liver transplantation.
|
Hepatology
|
1991
|
0.97
|
|
34
|
Lack of metabolic bone disease in patients with fracture of the femoral neck.
|
Aust N Z J Med
|
1981
|
0.96
|
|
35
|
Effects of immunosuppressants on receptor activator of NF-kappaB ligand and osteoprotegerin production by human osteoblastic and coronary artery smooth muscle cells.
|
Biochem Biophys Res Commun
|
2001
|
0.96
|
|
36
|
Osteoprotegerin mitigates tail suspension-induced osteopenia.
|
Bone
|
2000
|
0.94
|
|
37
|
RANK ligand.
|
Int J Biochem Cell Biol
|
2006
|
0.92
|
|
38
|
Adenoviral delivery of osteoprotegerin ameliorates bone resorption in a mouse ovariectomy model of osteoporosis.
|
Mol Ther
|
2001
|
0.92
|
|
39
|
Unique microstructural design of ceramic scaffolds for bone regeneration under load.
|
Acta Biomater
|
2013
|
0.92
|
|
40
|
Combined treatment with PTH (1-34) and OPG increases bone volume and uniformity of mineralization in aged ovariectomized rats.
|
Bone
|
2005
|
0.91
|
|
41
|
Quantitative bone histology in the hypercalcemia of malignant disease.
|
J Clin Endocrinol Metab
|
1982
|
0.90
|
|
42
|
The effect of age on bone composition and viability in the femoral head.
|
J Bone Joint Surg Am
|
1985
|
0.90
|
|
43
|
Tumor necrosis factor enhances parathyroid hormone-related protein-induced hypercalcemia and bone resorption without inhibiting bone formation in vivo.
|
Cancer Res
|
1997
|
0.90
|
|
44
|
Effect of aluminum on normal and uremic rats: tissue distribution, vitamin D metabolites, and quantitative bone histology.
|
Calcif Tissue Int
|
1983
|
0.88
|
|
45
|
The effect of osteoprotegerin administration on the intra-tibial growth of the osteoblastic LuCaP 23.1 prostate cancer xenograft.
|
Clin Exp Metastasis
|
2004
|
0.88
|
|
46
|
Bone metabolism in chronic renal failure.
|
Miner Electrolyte Metab
|
1982
|
0.88
|
|
47
|
Growth retardation and renal osteodystrophy in children with chronic renal failure.
|
J Pediatr
|
1983
|
0.84
|
|
48
|
The effect of low-dose cyclical etidronate and calcium on bone mass in early postmenopausal women.
|
Osteoporos Int
|
1993
|
0.84
|
|
49
|
Repairing a critical-sized bone defect with highly porous modified and unmodified baghdadite scaffolds.
|
Acta Biomater
|
2012
|
0.84
|
|
50
|
The pathogenesis of osteoarthritis of the hip. Evidence for primary osteocyte death.
|
Clin Orthop Relat Res
|
1987
|
0.83
|
|
51
|
Bone histology in young adult osteoporosis.
|
J Clin Pathol
|
1989
|
0.81
|
|
52
|
The determination of bone viability: a histochemical method for identification of lactate dehydrogenase activity in osteocytes in fresh calcified and decalcified sections of human bone.
|
Pathology
|
1982
|
0.81
|
|
53
|
Osteoprotegerin ameliorates sciatic nerve crush induced bone loss.
|
J Orthop Res
|
2001
|
0.81
|
|
54
|
Quantitative bone histology in children with chronic renal failure.
|
Kidney Int
|
1982
|
0.81
|
|
55
|
Pathologic fracture due to severe osteomalacia following low-dose diphosphonate treatment of Paget's disease of bone.
|
Aust N Z J Med
|
1983
|
0.81
|
|
56
|
The effects of osteoprotegerin on the mechanical properties of rat bone.
|
J Mater Sci Mater Med
|
2001
|
0.80
|
|
57
|
Bone metabolism in systemic mastocytosis. A case report.
|
J Bone Joint Surg Am
|
1981
|
0.79
|
|
58
|
Effects of human tumor cell lines on local new bone formation in vivo.
|
Calcif Tissue Int
|
1997
|
0.79
|
|
59
|
The effect of long-term low-dose diphosphonate treatment on rat bone.
|
Clin Orthop Relat Res
|
1982
|
0.77
|
|
60
|
Effect of aluminum and parathyroid hormone on osteoblasts and bone mineralization in chronic renal failure.
|
Calcif Tissue Int
|
1984
|
0.76
|
|
61
|
Treatment of hemodialysis bone disease with 24,25-(OH)2D3 and 1,25-(OH)2D3 alone or in combination.
|
Miner Electrolyte Metab
|
1985
|
0.76
|
|
62
|
The pathogenesis of idiopathic hypercalciuria: evidence for parathyroid hyperfunction.
|
Q J Med
|
1984
|
0.76
|
|
63
|
Adult osteosclerosis.
|
Metab Bone Dis Relat Res
|
1984
|
0.76
|
|
64
|
Metabolic studies in kidney stone disease.
|
Q J Med
|
1992
|
0.76
|
|
65
|
Mathematical modeling of postmenopausal osteoporosis and its treatment by the anti-catabolic drug denosumab.
|
Int J Numer Method Biomed Eng
|
2013
|
0.76
|
|
66
|
Bone metabolism in idiopathic juvenile osteoporosis: a case report.
|
Calcif Tissue Int
|
1983
|
0.75
|
|
67
|
Immobilization hypercalcaemia due to low bone formation and responding to intravenous sodium sulphate.
|
Postgrad Med J
|
1986
|
0.75
|
|
68
|
Treatment of Paget's disease of bone with a combination of intranasal salmon calcitonin and oral calcium and thiazide.
|
Calcif Tissue Int
|
1991
|
0.75
|
|
69
|
Aluminium-related bone disease presenting with calcaneal stress fractures.
|
Br J Rheumatol
|
1993
|
0.75
|
|
70
|
Long-term experience with a calcium-thiazide treatment for Paget's disease of bone.
|
Miner Electrolyte Metab
|
1982
|
0.75
|
|
71
|
Mitogenic lectin concanavalin A induces calvarial bone formation in vivo via indomethacin-sensitive pathway.
|
Calcif Tissue Int
|
1997
|
0.75
|
|
72
|
Treatment of childhood renal osteodystrophy with calcitriol or ergocalciferol.
|
Clin Nephrol
|
1985
|
0.75
|
|
73
|
Aluminum and renal bone disease in Australia.
|
Kidney Int Suppl
|
1986
|
0.75
|
|
74
|
Change from continuous epidural infusion to patient-controlled epidural analgesia on the labour ward of a large district general hospital.
|
Int J Obstet Anesth
|
2006
|
0.75
|
|
75
|
Quantitative bone histology in end-stage renal failure.
|
Prog Biochem Pharmacol
|
1980
|
0.75
|
|
76
|
The pathogenesis of renal osteodystrophy: role of vitamin D, aluminium, parathyroid hormone, calcium and phosphorus.
|
Q J Med
|
1985
|
0.75
|
|
77
|
Prurigo nodularis and aluminium overload in maintenance haemodialysis.
|
Lancet
|
1992
|
0.75
|