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L Ratner

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Top papers

Rank Title Journal Year PubWeight™‹?›
1 Complete nucleotide sequence of the AIDS virus, HTLV-III. Nature 1985 30.62
2 A molecular clone of HTLV-III with biological activity. Nature 1985 8.30
3 Myristoylation-dependent replication and assembly of human immunodeficiency virus 1. Proc Natl Acad Sci U S A 1990 8.23
4 Complete nucleotide sequences of functional clones of the AIDS virus. AIDS Res Hum Retroviruses 1987 7.85
5 The Vpr protein of human immunodeficiency virus type 1 influences nuclear localization of viral nucleic acids in nondividing host cells. Proc Natl Acad Sci U S A 1994 7.85
6 Sensitivity of human immunodeficiency virus type 1 to the fusion inhibitor T-20 is modulated by coreceptor specificity defined by the V3 loop of gp120. J Virol 2000 6.71
7 The sor gene of HIV-1 is required for efficient virus transmission in vitro. Science 1987 6.16
8 Identification of a determinant within the human immunodeficiency virus 1 surface envelope glycoprotein critical for productive infection of primary monocytes. Proc Natl Acad Sci U S A 1991 5.26
9 Macrophage tropism determinants of human immunodeficiency virus type 1 in vivo. J Virol 1992 5.19
10 Infectious mutants of HTLV-III with changes in the 3' region and markedly reduced cytopathic effects. Science 1986 4.17
11 Human immunodeficiency virus type 1 viral protein R localization in infected cells and virions. J Virol 1993 4.16
12 Identification of human immunodeficiency virus type 1 Gag protein domains essential to membrane binding and particle assembly. J Virol 1994 3.85
13 Human immunodeficiency virus type 1 negative factor is a transcriptional silencer. Proc Natl Acad Sci U S A 1989 3.65
14 Relationship of human immunodeficiency virus type 1 sequence heterogeneity to stage of disease. Proc Natl Acad Sci U S A 1992 3.19
15 Transactivation induced by human T-lymphotropic virus type III (HTLV III) maps to a viral sequence encoding 58 amino acids and lacks tissue specificity. Virology 1986 3.15
16 Membrane binding of human immunodeficiency virus type 1 matrix protein in vivo supports a conformational myristyl switch mechanism. J Virol 1997 3.07
17 Dual regulation of silent and productive infection in monocytes by distinct human immunodeficiency virus type 1 determinants. J Virol 1992 2.62
18 Characterization of long terminal repeat sequences of HTLV-III. Science 1985 2.56
19 Viral protein R regulates nuclear import of the HIV-1 pre-integration complex. EMBO J 1998 2.56
20 Development of leukemia in mice transgenic for the tax gene of human T-cell leukemia virus type I. Proc Natl Acad Sci U S A 1995 2.43
21 Sensitivity of human immunodeficiency virus type 1 to fusion inhibitors targeted to the gp41 first heptad repeat involves distinct regions of gp41 and is consistently modulated by gp120 interactions with the coreceptor. J Virol 2001 2.38
22 Human-proto-oncogene nucleotide sequences corresponding to the transforming region of simian sarcoma virus. Science 1984 2.32
23 Viral protein R of human immunodeficiency virus types 1 and 2 is dispensable for replication and cytopathogenicity in lymphoid cells. J Virol 1989 2.28
24 Interferon action: two distinct pathways for inhibition of protein synthesis by double-stranded RNA. Proc Natl Acad Sci U S A 1978 2.22
25 Construction and characterization of infectious human T-cell leukemia virus type 1 molecular clones. Virology 1994 2.14
26 HTLV-III, LAV, ARV are variants of same AIDS virus. Nature 1985 2.03
27 Selective ablation of human T-cell lymphotropic virus type 1 p12I reduces viral infectivity in vivo. Blood 1998 2.03
28 Analysis of the critical domain in the V3 loop of human immunodeficiency virus type 1 gp120 involved in CCR5 utilization. J Virol 1999 2.02
29 Polymorphism of the 3' open reading frame of the virus associated with the acquired immune deficiency syndrome, human T-lymphotropic virus type III. Nucleic Acids Res 1985 2.01
30 Human immunodeficiency virus type 1 coreceptor switching: V1/V2 gain-of-fitness mutations compensate for V3 loss-of-fitness mutations. J Virol 2006 2.00
31 Immortalization of CD4(+) and CD8(+) T lymphocytes by human T-cell leukemia virus type 1 Tax mutants expressed in a functional molecular clone. J Virol 1999 1.94
32 A leucine triplet repeat sequence (LXX)4 in p6gag is important for Vpr incorporation into human immunodeficiency virus type 1 particles. J Virol 1995 1.93
33 Sequences of the 5' portion of the human c-sis gene: characterization of the transcriptional promoter and regulation of expression of the protein product by 5' untranslated mRNA sequences. Nucleic Acids Res 1987 1.91
34 Transformation of NIH 3T3 cells by a human c-sis cDNA clone. Nature 1984 1.73
35 Multidrug resistance transporters and modulation. Curr Opin Oncol 2000 1.71
36 Interferon, double-stranded RNA and RNA degradation. Fractionation of the endonucleaseINT system into two macromolecular components; role of a small molecule in nuclease activation. Biochem Biophys Res Commun 1978 1.70
37 Viral protein R regulates docking of the HIV-1 preintegration complex to the nuclear pore complex. J Biol Chem 1998 1.68
38 Role of the carboxy-terminal portion of the HIV-1 transmembrane protein in viral transmission and cytopathogenicity. AIDS Res Hum Retroviruses 1989 1.67
39 Killing HIV-infected cells by transduction with an HIV protease-activated caspase-3 protein. Nat Med 1999 1.63
40 Functional role of pX open reading frame II of human T-lymphotropic virus type 1 in maintenance of viral loads in vivo. J Virol 2000 1.61
41 Human immunodeficiency virus type 1 Nef protein inhibits NF-kappa B induction in human T cells. J Virol 1992 1.59
42 Transforming potential of human c-sis nucleotide sequences encoding platelet-derived growth factor. Science 1984 1.58
43 Human immunodeficiency virus type 1 tropism for T-lymphoid cell lines: role of the V3 loop and C4 envelope determinants. J Virol 1996 1.55
44 Limited sequence heterogeneity among biologically distinct human immunodeficiency virus type 1 isolates from individuals involved in a clustered infectious outbreak. Proc Natl Acad Sci U S A 1990 1.54
45 Human T-cell leukemia virus type 1 pX-I and pX-II open reading frames are dispensable for the immortalization of primary lymphocytes. J Virol 1998 1.52
46 Particle size determinants in the human immunodeficiency virus type 1 Gag protein. J Virol 1998 1.48
47 Replication of human immunodeficiency virus 1 and Moloney murine leukemia virus is inhibited by different heteroatom-containing analogs of myristic acid. Proc Natl Acad Sci U S A 1989 1.47
48 Cooperative effects of the human immunodeficiency virus type 1 envelope variable loops V1 and V3 in mediating infectivity for T cells. J Virol 1996 1.45
49 Analysis of the function of viral protein X (VPX) of HIV-2. Virology 1989 1.42
50 HIV-2 viral protein X association with the GAG p27 capsid protein. Virology 1994 1.35
51 Human T-lymphotropic virus type 1 open reading frame I p12(I) is required for efficient viral infectivity in primary lymphocytes. J Virol 2000 1.34
52 In vitro CD4+ lymphocyte transformation and infection in a rabbit model with a molecular clone of human T-cell lymphotrophic virus type 1. J Virol 1996 1.33
53 Actin cytoskeletal reorganizations and coreceptor-mediated activation of rac during human immunodeficiency virus-induced cell fusion. J Virol 2004 1.32
54 Myristoylation-enhanced binding of the HIV-1 Nef protein to T cell skeletal matrix. Virology 1993 1.32
55 The C-terminal proline-rich tail of human immunodeficiency virus type 2 Vpx is necessary for nuclear localization of the viral preintegration complex in nondividing cells. J Virol 2000 1.29
56 Human immunodeficiency virus type 1 capsid formation in reticulocyte lysates. J Virol 1996 1.27
57 Incorporation of 12-methoxydodecanoate into the human immunodeficiency virus 1 gag polyprotein precursor inhibits its proteolytic processing and virus production in a chronically infected human lymphoid cell line. Proc Natl Acad Sci U S A 1991 1.27
58 Limited sequence variation in human T-lymphotropic virus type 1 isolates from North American and African patients. Virology 1991 1.24
59 Nucleotide sequence analysis of a variant human T-cell leukemia virus (HTLV-Ib) provirus with a deletion in pX-I. J Virol 1985 1.23
60 Nucleotide sequence of transforming human c-sis cDNA clones with homology to platelet-derived growth factor. Nucleic Acids Res 1985 1.18
61 Conserved cysteine residues in the human immunodeficiency virus type 1 transmembrane envelope protein are essential for precursor envelope cleavage. J Virol 1992 1.15
62 Endovascular gastrointestinal stapler device malfunction during laparoscopic nephrectomy: early recognition and management. J Urol 2000 1.15
63 Specificity of polymerase chain amplification reactions for human immunodeficiency virus type 1 DNA sequences. AIDS Res Hum Retroviruses 1989 1.15
64 Interferon, double-stranded RNA and RNA degradation. Characteristics of an endonuclease activity. Eur J Biochem 1977 1.14
65 Arginine residues in the C-terminus of HIV-1 Vpr are important for nuclear localization and cell cycle arrest. Virology 1998 1.14
66 Role of asparagine-linked glycosylation in human immunodeficiency virus type 1 transmembrane envelope function. Virology 1992 1.14
67 Particle assembly and Vpr expression in human immunodeficiency virus type 1-infected cells demonstrated by immunoelectron microscopy. J Gen Virol 1994 1.14
68 The HTLV receptor is a widely expressed protein. Virology 2000 1.13
69 Killing of primary CD4+ T cells by non-syncytium-inducing macrophage-tropic human immunodeficiency virus type 1. Proc Natl Acad Sci U S A 1994 1.12
70 Structure-function relationships of the HIV-1 envelope V3 loop tropism determinant: evidence for two distinct conformations. AIDS 1993 1.09
71 Proliferation response to interleukin-2 and Jak/Stat activation of T cells immortalized by human T-cell lymphotropic virus type 1 is independent of open reading frame I expression. J Virol 1999 1.07
72 The contribution of NF-kappa B activity to spontaneous proliferation and resistance to apoptosis in human T-cell leukemia virus type 1 Tax-induced tumors. Blood 2001 1.07
73 Phosphorylation of human immunodeficiency virus type 1 Vpr regulates cell cycle arrest. J Virol 2000 1.05
74 HIV-1 Nef protein inhibits the recruitment of AP-1 DNA-binding activity in human T-cells. Virology 1993 1.04
75 Temporal regulation of viral and cellular gene expression during human T-lymphotropic virus type I-mediated lymphocyte immortalization. J Virol 1991 1.03
76 Rapid phenotypic drug susceptibility assay for HIV-1 with a CCR5 expressing indicator cell line. J Virol Methods 2000 1.02
77 Quantification of human T-cell lymphotropic virus type 1 proviral load by quantitative competitive polymerase chain reaction. J Virol Methods 1998 1.01
78 Identification of HIV1 determinants for T lymphoid cell line infection. Virology 1993 1.00
79 Human immunodeficiency virus type 1 Nef protein down-regulates transcription factors NF-kappa B and AP-1 in human T cells in vitro after T-cell receptor stimulation. J Virol 1994 1.00
80 HIV-1 Nef protein downregulation of CD4 surface expression: relevance of the lck binding domain of CD4. Virology 1995 0.99
81 Cytotoxic factors secreted by cells infected by human immunodeficiency virus type I. AIDS Res Hum Retroviruses 1987 0.98
82 Attenuation of HIV-1 infectivity by an inhibitor of oligosaccharide processing. AIDS Res Hum Retroviruses 1990 0.98
83 Evidence for common structural determinants of human immunodeficiency virus type 1 coreceptor activity provided through functional analysis of CCR5/CXCR4 chimeric coreceptors. J Virol 2001 0.96
84 Demonstration of two distinct cytopathic effects with syncytium formation-defective human immunodeficiency virus type 1 mutants. J Virol 1991 0.96
85 Evolution of sequence divergence among human immunodeficiency virus type 1 isolates derived from a blood donor and a recipient. Pediatr Res 1993 0.96
86 Systemic treatment of Kaposi's sarcoma: current status and future directions. AIDS 1994 0.95
87 Human immunodeficiency virus type 2 Vpx-Gag interaction. J Virol 1998 0.95
88 The tax protein of human T-cell leukemia virus type 1 mediates the transactivation of the c-sis/platelet-derived growth factor-B promoter through interactions with the zinc finger transcription factors Sp1 and NGFI-A/Egr-1. J Biol Chem 1997 0.95
89 Differences among HIV-1 variants in their ability to elicit secretion of TNF-alpha. J Immunol 2000 0.95
90 HIV type 2 Vpx interaction with Gag and incorporation into virus-like particles. AIDS Res Hum Retroviruses 2001 0.94
91 Relationship between productive HIV-1 infection of macrophages and CCR5 utilization. Virology 1999 0.94
92 Reduced fracture risk with early corticosteroid withdrawal after kidney transplant. Am J Transplant 2011 0.94
93 Novel role for interleukin-2 receptor-Jak signaling in retrovirus transmission. J Virol 2009 0.93
94 Viral protein U (Vpu)-mediated enhancement of human immunodeficiency virus type 1 particle release depends on the rate of cellular proliferation. J Virol 2001 0.93
95 Highly localized tracks of human immunodeficiency virus type 1 Nef in the nucleus of cells of a human CD4+ T-cell line. Proc Natl Acad Sci U S A 1993 0.93
96 The mitogenic activity of human T-cell leukemia virus type I is T-cell associated and requires the CD2/LFA-3 activation pathway. J Virol 1993 0.92
97 Nef and LTR sequence variation from sequentially derived human immunodeficiency virus type 1 isolates. Virology 1995 0.91
98 Regulation of human immunodeficiency virus Nef protein by phosphorylation. Virology 1994 0.91
99 Cytokine expression and tumorigenicity of large granular lymphocytic leukemia cells from mice transgenic for the tax gene of human T-cell leukemia virus type I. Blood 1997 0.91
100 Role of HIV-1 envelope V3 loop cleavage in cell tropism. AIDS Res Hum Retroviruses 1993 0.91
101 Apocrine adenocarcinoma presenting as a large ulcerated axillary mass. Dermatol Surg 1997 0.91
102 c-sis/PDGF-B promoter transactivation by the Yax protein of human T-cell leukemia virus type 1. J Biol Chem 1996 0.90
103 Characterization of envelope glycoprotein mutants for human T-cell leukemia virus type 1 infectivity and immortalization. J Virol 2001 0.89
104 The N-terminal matrix domain of HIV-1 Gag is sufficient but not necessary for viral protein U-mediated enhancement of particle release through a membrane-targeting mechanism. Virology 2000 0.89
105 A novel inducible expression system to study transdominant mutants of HIV-1 Vpr. Virology 2001 0.88
106 Chemotherapy consisting of doxorubicin, bleomycin, vinblastine, and dacarbazine with granulocyte-colony-stimulating factor in HIV-infected patients with newly diagnosed Hodgkin's disease: a prospective, multi-institutional AIDS clinical trials group study (ACTG 149). J Acquir Immune Defic Syndr 2000 0.87
107 Immortalization of T lymphocytes by human T-cell leukemia virus type 1 is independent of the tax-CBP/p300 interaction. J Virol 2000 0.87
108 Simian immunodeficiency virus negative factor suppresses the level of viral mRNA in COS cells. J Virol 1991 0.87
109 Analysis of p53 inactivation in a human T-cell leukemia virus type 1 Tax transgenic mouse model. J Virol 2001 0.86
110 Productive infection of CD34+-cell-derived megakaryocytes by X4 and R5 HIV-1 isolates. Virology 2000 0.86
111 Structure and expression of the human T-cell leukemia virus type 1 envelope protein. Virology 1994 0.86
112 Interferon-associated, dsRNA-dependent enzyme activities in a mutant 3T6 cell engaged in the semiconstitutive synthesis of interferon. Cell 1978 0.86
113 Transgenic mouse models for HTLV-I infection. J Acquir Immune Defic Syndr Hum Retrovirol 1996 0.85
114 Suspected vascular trauma of the extremities: the role of arteriography in proximity injuries. J Trauma 1986 0.85
115 Trans-activation of long terminal repeat sequence-mediated gene expression is not a property of type D retrovirus replication. J Gen Virol 1987 0.85
116 Interaction of human immunodeficiency virus type 2 Vpx and invariant chain. J Virol 2000 0.85
117 Alpha 1-antitrypsin phenotypes in patients with abdominal aortic aneurysms. J Surg Res 1990 0.85
118 Dysregulated myelopoiesis in mice lacking Jak3. Blood 1999 0.85
119 Messenger RNA methylation, translation and degradation in extracts of interferon-treated cells. Tex Rep Biol Med 1977 0.85
120 HIV-1 V3 envelope sequences required for macrophage infection. AIDS 1995 0.84
121 High-dose platinum for the treatment of refractory ovarian cancer. Gynecol Oncol 1981 0.83
122 Oncogenes: their role in neoplastic transformation. Annu Rev Microbiol 1985 0.82
123 The identifier concept: variables to stratify patient costs within cardiothoracic surgical diagnostic related groups. J Thorac Cardiovasc Surg 1988 0.82
124 Formation and release of virus-like particles by HIV-1 matrix protein. AIDS 1999 0.82
125 Recurrent focal segmental glomerulosclerosis in the renal allograft: single center experience in the era of modern immunosuppression. Clin Nephrol 2010 0.82
126 Distinct human immunodeficiency virus strains in the bone marrow are associated with the development of thrombocytopenia. J Virol 1999 0.82
127 Cell surface proteins binding to recombinant soluble HIV-1 and HIV-2 transmembrane proteins. AIDS 1993 0.82
128 Alterations in spliced and unspliced HIV-1-specific RNA detection in peripheral blood mononuclear cells of individuals with varying CD4-positive lymphocyte counts. AIDS Res Hum Retroviruses 1993 0.81
129 Deletion of Alu sequences in the fifth c-sis intron in individuals with meningiomas. J Clin Invest 1990 0.81
130 Phase I study of pegylated liposomal doxorubicin and the multidrug-resistance modulator, valspodar. Br J Cancer 2005 0.81
131 Tracking the assembly pathway of human immunodeficiency virus type 1 Gag deletion mutants by immunogold labeling. Appl Immunohistochem Mol Morphol 2001 0.80
132 Alteration in lymphoid chimerism associated with cytomegalovirus infection after bone marrow transplantation. Transplantation 1979 0.79
133 Weekly oral etoposide in patients with Kaposi's sarcoma associated with human immunodeficiency virus infection: a phase I multicenter trial of the AIDS Clinical Trials Group. J Acquir Immune Defic Syndr Hum Retrovirol 1995 0.78
134 Laparoscopic donor nephrectomy. Semin Laparosc Surg 2000 0.77
135 Will transplant immunogenetics lead to better graft survival in blacks? Racial variability in the accuracy of tissue typing for organ donation: the fourth American workshop. Transplant Proc 1987 0.77
136 An outbreak of phototoxic dermatitis due to limes. Am J Epidemiol 1987 0.77
137 Sera from HIV-1 infected individuals in all stages of disease preferentially recognize the V3 loop of the prototypic macrophage-tropic glycoprotein gp120 ADA. Mol Immunol 1995 0.77
138 The use of new antiretroviral therapy in combination with chemotherapy. Curr Opin Oncol 1997 0.77
139 CD3-dependent lymphocyte activation by human T cell leukaemia virus type I-producing T cells. J Gen Virol 1994 0.76
140 Effects of mutant Vpr/Vpx on HIV-2 assembly demonstrated by immunoelectron microscopy. Proc Natl Sci Counc Repub China B 2001 0.76
141 Molecular biology of human T-lymphotropic retroviruses. Cancer Res 1985 0.76
142 Prevalence of HTLV-I-associated T-cell lymphoma. Am J Hematol 2001 0.76
143 Immunoblastic lymphoma of T-cell type in a chronically immunosuppressed renal transplant recipient. Am J Clin Pathol 1990 0.75
144 Interferon as an inhibitor of cell growth: studies with mouse melanoma cells. Proc Soc Exp Biol Med 1980 0.75
145 Adverse prognostic influence of hepatitis B virus infection in acute lymphoblastic leukemia. Cancer 1986 0.75
146 Mechanism of leukemogenesis by human T-cell leukemia virus types I and II: role of the lor gene. Cancer Detect Prev 1987 0.75
147 Treatment of chemotherapy-resistant advanced ovarian cancer with a combination of cyclophosphamide, hexamethylmelamine, adriamycin, and cis-diamminedichloroplatinum (CHAP). Gynecol Oncol 1981 0.75
148 Chemotherapy of recurrent ovarian carcinoma with cis-dichlorodiammine platinum II and adriamycin. Obstet Gynecol 1980 0.75
149 Biology and molecular biology of human immunodeficiency virus. Pediatr Infect Dis J 1992 0.75
150 Molecular characterization of human T-lymphotropic leukemia virus type III associated with the acquired immunodeficiency syndrome. Princess Takamatsu Symp 1984 0.75
151 The dual kidney transplant registry. Transplant Proc 2001 0.75
152 Delta hepatitis outbreak in a group of patients with leukemia. Ann Intern Med 1986 0.75
153 AIDS 1997. Virology: overview. AIDS 1997 0.75
154 Oligoclonal V beta usage in vitro after in vivo exposure to pig xenoantigen extracorporeal pig liver perfusion. Transplant Proc 1994 0.75
155 Structure and expression of the c-sis gene and its relationship to sporadic meningiomas. Cancer Res 1991 0.75
156 DRGs, orthopedic surgery, and age at an academic medical center. Orthopedics 1988 0.75
157 Prevention of stress-induced erosive gastritis by parenteral administration of arachidonic acid. JPEN J Parenter Enteral Nutr 1991 0.75
158 Functional analysis of HIV1 and SIV Nef proteins. Res Virol 1992 0.75
159 Analogs of 3'-amino-3'-deoxyadenosine inhibit HIV-1 replication. AIDS Res Hum Retroviruses 1989 0.75
160 A study of change in clinical service for general surgical patients. QRB Qual Rev Bull 1988 0.75