PubRank

V M Holers

Author PubWeight™ 110.26‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 A critical role for murine complement regulator crry in fetomaternal tolerance. Science 2000 3.27
2 Markedly impaired humoral immune response in mice deficient in complement receptors 1 and 2. Proc Natl Acad Sci U S A 1996 2.71
3 The regulators of complement activation (RCA) gene cluster. Adv Immunol 1989 2.63
4 Cloning and characterization of cDNAs encoding the complete sequence of decay-accelerating factor of human complement. Proc Natl Acad Sci U S A 1987 2.62
5 Duration of preclinical rheumatoid arthritis-related autoantibody positivity increases in subjects with older age at time of disease diagnosis. Ann Rheum Dis 2007 2.38
6 Expression of complement receptors 1 and 2 on follicular dendritic cells is necessary for the generation of a strong antigen-specific IgG response. J Immunol 1998 1.96
7 Herpes simplex virus glycoproteins gC-1 and gC-2 bind to the third component of complement and provide protection against complement-mediated neutralization of viral infectivity. J Exp Med 1987 1.74
8 Mouse complement regulatory protein Crry/p65 uses the specific mechanisms of both human decay-accelerating factor and membrane cofactor protein. J Exp Med 1995 1.74
9 Modulation of renal disease in MRL/lpr mice genetically deficient in the alternative complement pathway factor B. J Immunol 2000 1.55
10 Mouse Crry/p65. Characterization of monoclonal antibodies and the tissue distribution of a functional homologue of human MCP and DAF. J Immunol 1993 1.50
11 Structural requirements for C3d,g/Epstein-Barr virus receptor (CR2/CD21) ligand binding, internalization, and viral infection. J Biol Chem 1990 1.48
12 Distinct receptor and regulatory properties of recombinant mouse complement receptor 1 (CR1) and Crry, the two genetic homologues of human CR1. J Exp Med 1992 1.46
13 Genomic organization and polymorphisms of the human C3d/Epstein-Barr virus receptor. J Biol Chem 1989 1.43
14 Association of rheumatoid arthritis treatment response and disease duration with declines in serum levels of IgM rheumatoid factor and anti-cyclic citrullinated peptide antibody. Arthritis Rheum 2004 1.43
15 Structure of complement receptor 2 in complex with its C3d ligand. Science 2001 1.40
16 Mouse complement receptors type 1 (CR1;CD35) and type 2 (CR2;CD21): expression on normal B cell subpopulations and decreased levels during the development of autoimmunity in MRL/lpr mice. J Immunol 1997 1.39
17 Cr2, a candidate gene in the murine Sle1c lupus susceptibility locus, encodes a dysfunctional protein. Immunity 2001 1.36
18 A molecular and immunochemical characterization of mouse CR2. Evidence for a single gene model of mouse complement receptors 1 and 2. J Immunol 1990 1.32
19 Blockade of antibody-induced glomerulonephritis with Crry-Ig, a soluble murine complement inhibitor. J Immunol 1998 1.32
20 Contribution of the innate immune system to autoimmune myocarditis: a role for complement. Nat Immunol 2001 1.30
21 The gene encoding decay-accelerating factor (DAF) is located in the complement-regulatory locus on the long arm of chromosome 1. J Exp Med 1987 1.29
22 Complement component C3 is not required for full expression of immune complex glomerulonephritis in MRL/lpr mice. J Immunol 2001 1.24
23 Purification and functional analysis of the polymorphic variants of the C3b/C4b receptor (CR1) and comparison with H, C4b-binding protein (C4bp), and decay accelerating factor (DAF). J Immunol 1985 1.23
24 Analysis of Epstein-Barr virus-binding sites on complement receptor 2 (CR2/CD21) using human-mouse chimeras and peptides. At least two distinct sites are necessary for ligand-receptor interaction. J Biol Chem 1991 1.19
25 Complement receptor 3 (CR3, Mac-1, integrin alpha M beta 2, CD11b/CD18) is required for tyrosine phosphorylation of paxillin in adherent and nonadherent neutrophils. J Cell Biol 1994 1.19
26 Mouse Crry/p65 is a regulator of the alternative pathway of complement activation. Eur J Immunol 1993 1.18
27 Identification of a third component of complement-binding glycoprotein of human platelets. J Clin Invest 1986 1.17
28 Identification of an alternative polyadenylation site in the human C3b/C4b receptor (complement receptor type 1) transcriptional unit and prediction of a secreted form of complement receptor type 1. J Exp Med 1988 1.16
29 Human peripheral blood monocytes display surface antigens recognized by monoclonal antinuclear antibodies. J Clin Invest 1985 1.15
30 Complement inhibitor, complement receptor 1-related gene/protein y-Ig attenuates intestinal damage after the onset of mesenteric ischemia/reperfusion injury in mice. J Immunol 2001 1.14
31 Normal polymorphic variations and transcription of the decay accelerating factor gene in paroxysmal nocturnal hemoglobinuria cells. Proc Natl Acad Sci U S A 1988 1.14
32 Complement activation as a mediator of antiphospholipid antibody induced pregnancy loss and thrombosis. Ann Rheum Dis 2002 1.13
33 Analysis of epitope expression and the functional repertoire of recombinant complement receptor 2 (CR2/CD21) in mouse and human cells. J Immunol 1989 1.12
34 Transgenic mice overexpressing the complement inhibitor crry as a soluble protein are protected from antibody-induced glomerular injury. J Exp Med 1998 1.08
35 Human complement C3b/C4b receptor (CR1) mRNA polymorphism that correlates with the CR1 allelic molecular weight polymorphism. Proc Natl Acad Sci U S A 1987 1.08
36 Epithelial secretion of C3 promotes colonization of the upper urinary tract by Escherichia coli. Nat Med 2001 1.06
37 Analysis of the human regulators of complement activation (RCA) gene cluster with yeast artificial chromosomes (YACs). Genomics 1992 1.06
38 Moesin, and not the murine functional homologue (Crry/p65) of human membrane cofactor protein (CD46), is involved in the entry of measles virus (strain Edmonston) into susceptible murine cell lines. J Gen Virol 1995 1.04
39 CD23 interacts with a new functional extracytoplasmic domain involving N-linked oligosaccharides on CD21. J Immunol 1994 1.03
40 An intronic silencer regulates B lymphocyte cell- and stage-specific expression of the human complement receptor type 2 (CR2, CD21) gene. J Immunol 1998 1.03
41 Increased expression of activation-induced cytidine deaminase is associated with anti-CCP and rheumatoid factor in rheumatoid arthritis. Scand J Immunol 2009 1.02
42 Structural and functional studies on the human C3b/C4b receptor (CR1) purified by affinity chromatography using a monoclonal antibody. Complement 1986 1.01
43 Structural gene for human membrane cofactor protein (MCP) of complement maps to within 100 kb of the 3' end of the C3b/C4b receptor gene. J Exp Med 1989 1.01
44 The interrelationship of complement-activation fragments and angiogenesis-related factors in early pregnancy and their association with pre-eclampsia. BJOG 2010 1.01
45 Epitope mapping using the X-ray crystallographic structure of complement receptor type 2 (CR2)/CD21: identification of a highly inhibitory monoclonal antibody that directly recognizes the CR2-C3d interface. J Immunol 2001 1.00
46 Structural studies in solution of the recombinant N-terminal pair of short consensus/complement repeat domains of complement receptor type 2 (CR2/CD21) and interactions with its ligand C3dg. Biochemistry 2001 1.00
47 Cigarette smoking, disease severity and autoantibody expression in African Americans with recent-onset rheumatoid arthritis. Ann Rheum Dis 2008 0.99
48 Crry and CD59 regulate complement in rat glomerular epithelial cells and are inhibited by the nephritogenic antibody of passive Heymann nephritis. J Immunol 1995 0.98
49 Complement activation pathways in murine immune complex-induced arthritis and in C3a and C5a generation in vitro. Clin Exp Immunol 2009 0.97
50 Resting B cells from New Zealand Black mice demonstrate a defect in apoptosis induction following surface IgM ligation. J Immunol 1996 0.96
51 The polymorphism of the C3b/C4b receptor in the normal population and in patients with systemic lupus erythematosus. Clin Exp Immunol 1987 0.96
52 Inhibiting the complement system does not reduce injury in renal ischemia reperfusion. J Am Soc Nephrol 2001 0.95
53 Analysis of C3b/C3d binding sites and factor I cofactor regions within mouse complement receptors 1 and 2. J Immunol 1994 0.94
54 T lymphocyte expression of complement receptor 2 (CR2/CD21): a role in adhesive cell-cell interactions and dysregulation in a patient with systemic lupus erythematosus (SLE). Clin Exp Immunol 1992 0.94
55 Modulation of mouse endotoxic fever by complement. Infect Immun 2002 0.93
56 Complement regulation in the rat glomerulus: Crry and CD59 regulate complement in glomerular mesangial and endothelial cells. Kidney Int 1995 0.93
57 Cigarette smoking and the risk of systemic lupus erythematosus and rheumatoid arthritis. Ann Rheum Dis 2006 0.93
58 Solution structures of complement components by X-ray and neutron scattering and analytical ultracentrifugation. Biochem Soc Trans 2002 0.92
59 Gamma-glutamyl transpeptidase, an ecto-enzyme regulator of intracellular redox potential, is a component of TM4 signal transduction complexes. Eur J Immunol 1998 0.91
60 Characterization of a complement receptor 2 (CR2, CD21) ligand binding site for C3. An initial model of ligand interaction with two linked short consensus repeat modules. J Immunol 1995 0.91
61 A site in the complement receptor 2 (CR2/CD21) silencer is necessary for lineage specific transcriptional regulation. Int Immunol 2001 0.91
62 Cross-linking CD21/CD35 or CD19 increases both B7-1 and B7-2 expression on murine splenic B cells. J Immunol 1998 0.91
63 Generation of recombinant human C3dg tetramers for the analysis of CD21 binding and function. J Immunol Methods 2001 0.91
64 Regulation of nuclear antigen expression on the cell surface of human monocytes. J Immunol 1992 0.91
65 Complement activation and mortality during an acute episode of thrombotic thrombocytopenic purpura. J Thromb Haemost 2013 0.90
66 Co-ligation of mouse complement receptors 1 and 2 with surface IgM rescues splenic B cells and WEHI-231 cells from anti-surface IgM-induced apoptosis. Eur J Immunol 1995 0.90
67 Complement is activated in kidney by endotoxin but does not cause the ensuing acute renal failure. Kidney Int 2000 0.88
68 CR2/CD21 proximal promoter activity is critically dependent on a cell type-specific repressor. J Immunol 2001 0.88
69 Gamma-glutamyl transpeptidase is up-regulated on memory T lymphocytes. Int Immunol 1999 0.87
70 Analysis of C3b/C4b receptor (CR1) polymorphic variants by tryptic peptide mapping. Mol Immunol 1986 0.87
71 Characterization of the human complement receptor 2 (CR2, CD21) promoter reveals sequences shared with regulatory regions of other developmentally restricted B cell proteins. J Immunol 1991 0.87
72 Complement receptors. Curr Opin Immunol 1992 0.86
73 The ectoenzyme gamma-glutamyl transpeptidase regulates antiproliferative effects of S-nitrosoglutathione on human T and B lymphocytes. J Immunol 1999 0.86
74 Expression and function of membrane regulators of complement on rat astrocytes in culture. Immunology 1996 0.86
75 Expression of human complement receptor 2 (CR2, CD21) in Cr2-/- mice restores humoral immune function. J Immunol 2000 0.86
76 CD21 augments antigen presentation in immune individuals. Eur J Immunol 1997 0.86
77 Complement opsonization is required for presentation of immune complexes by resting peripheral blood B cells. J Immunol 1998 0.85
78 Complement component c5a is integral to the febrile response of mice to lipopolysaccharide. Neuroimmunomodulation 2005 0.85
79 Characterization of C3-binding proteins on mouse neutrophils and platelets. J Immunol 1997 0.84
80 Supervised machine learning and logistic regression identifies novel epistatic risk factors with PTPN22 for rheumatoid arthritis. Genes Immun 2010 0.83
81 Macrophage-colony-stimulating factor regulates expression of the integrins alpha 4 beta 1 and alpha 5 beta 1 by murine bone marrow macrophages. Proc Natl Acad Sci U S A 1995 0.83
82 Renal, central nervous system and pancreatic overexpression of recombinant soluble Crry in transgenic mice. A novel means of protection from complement-mediated injury. Immunopharmacology 1999 0.82
83 Studies of Filipino patients with systemic lupus erythematosus: autoantibody profile of first-degree relatives. Lupus 2010 0.82
84 Smoking is not associated with autoantibody production in systemic lupus erythematosus patients, unaffected first-degree relatives, nor healthy controls. Lupus 2014 0.82
85 Activation of complement mediates antiphospholipid antibody-induced pregnancy loss. Lupus 2003 0.82
86 Expression of the murine complement regulatory protein crry by glial cells and neurons. Glia 1999 0.81
87 Treatment of refractory chronic demyelinating polyneuropathy with lymphoid irradiation. Muscle Nerve 1985 0.81
88 Genetics of the complement system and rheumatic diseases. Rheum Dis Clin North Am 1992 0.81
89 Lack of clinical benefit after treatment of systemic sclerosis with total lymphoid irradiation. J Rheumatol 1989 0.80
90 Increased serum C3 levels in Crry transgenic mice partially abrogates its complement inhibitory effects. Clin Exp Immunol 2004 0.80
91 Inhibition of complement component C3 reduces vein graft atherosclerosis in apolipoprotein E3-Leiden transgenic mice. Circulation 2006 0.79
92 The serum resistance of malaria-infected erythrocytes. Immunology 1997 0.79
93 Complement deficiency states, disease susceptibility, and infection risk in systemic lupus erythematosus. Arthritis Rheum 1999 0.79
94 Epstein-Barr virus/C3d receptor (CR2, CD21) activated by its extracellular ligands regulates pp105 phosphorylation through two distinct pathways. Eur J Immunol 1995 0.78
95 Expression of a soluble complement inhibitor protects transgenic mice from antibody-induced acute renal failure. J Am Soc Nephrol 2001 0.78
96 Expression of the fibronectin receptor VLA-5 is regulated during human B cell differentiation and activation. Clin Exp Immunol 1991 0.78
97 EBV binds to lymphocytes of transgenic mice that express the human CR2 gene. Virus Res 1997 0.77
98 Induction of IL-4 and IL-6 synthesis in vitro: variation in signaling requirements and kinetics are dependent on the anatomic source of the responding mononuclear cells. Reg Immunol 1992 0.77
99 Structure of complement receptor (CR) 2 and CR2-C3d complexes. Biochem Soc Trans 2002 0.77
100 Characterization of rat complement receptors and regulatory proteins. CR2 and Crry are conserved, and the C3b receptor of neutrophils and platelets is distinct from CR1. J Immunol 1995 0.76
101 Polymorphisms of the regulators of complement activation gene cluster. Complement Inflamm 1990 0.75
102 A prototype pathogen bound ex vivo to human erythrocyte complement receptor 1 via bispecific monoclonal antibody complexes is cleared to the liver in a mouse model. Eur J Immunol 1999 0.75
103 CD59 homologue regulates complement-dependent cytolysis of rat Schwann cells. J Neuroimmunol 1996 0.75
104 Characterization of C3 receptors on cultured rat glomerular endothelial cells. Kidney Int 1997 0.75
105 Expression of functional human Epstein-Barr virus/C3d receptor ([CR2] CD21) on insulinoma cell line. Induction of tumor rejection but not diabetes in syngeneic rats. Diabetes 1991 0.75