T H Huisman

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Top papers

Rank Title Journal Year PubWeight™‹?›
1 Studies on the heterogeneity of hemoglobin. IX. The use of Tris(hydroxymethyl)aminomethanehcl buffers in the anion-exchange chromatography of hemoglobins. J Chromatogr 1965 4.17
2 Evidence for multiple structural genes for the gamma chain of human fetal hemoglobin. Proc Natl Acad Sci U S A 1968 3.05
3 DNA sequence variation associated with elevated fetal G gamma globin production. Blood 1985 2.41
4 Absence of messenger RNA and gene DNA for beta-globin chains in hereditary persistence of fetal hemoglobin. Cell 1976 2.10
5 Studies on the heterogeneity of hemoglobin. 13. Chromatography of various human and animal hemoglobin types on DEAE-Sephadex. J Chromatogr 1968 2.07
6 Globin chain electrophoresis: a new approach to the determination of the G gamma/A gamma ratio in fetal haemoglobin and to studies of globin synthesis. Br J Haematol 1980 1.99
7 The present status of the heterogeneity of fetal hemoglobin in beta-thalassemia: an attempt to unify some observations in thalassemia and related conditions. Ann N Y Acad Sci 1974 1.99
8 Microchromatography of hemoglobins. II. A simplified procedure for the determination of hemoglobin A2. J Lab Clin Med 1975 1.91
9 A gene deletion ending within a complex array of repeated sequences 3' to the human beta-globin gene cluster. Proc Natl Acad Sci U S A 1986 1.80
10 Multiple cistrons for fetal hemoglobin in man. Ann N Y Acad Sci 1974 1.53
11 Determination of the glycosylated hemoglobins (HB AI) with a new microcolumn procedure. Suitability of the technique for assessing the clinical management of diabetes mellitus. Diabetes 1978 1.51
12 Detection of common deletional alpha-thalassemia-2 determinants by PCR. Am J Hematol 1994 1.44
13 Normal fetal hemoglobin levels in the sudden infant death syndrome. N Engl J Med 1989 1.42
14 An improved method for quantitative determination of human fetal hemoglobin. Anal Biochem 1970 1.41
15 Hb Sun Prairie or alpha(2)130(H13)Ala----Pro beta 2, a new unstable variant occurring in low quantities. Hemoglobin 1990 1.39
16 The detection of hemoglobin variants by isoelectrofocusing using EDTA-collected and filter paper-dried cord blood specimens. Am J Clin Pathol 1990 1.39
17 The levels of abnormal hemoglobin in persons with heterozygosities for an alpha chain variant and for beta-thalassemia. Hemoglobin 1997 1.38
18 Separation of human hemoglobins by DEAE-cellulose chromatography using glycine-KCN-NaC1 developers. Hemoglobin 1977 1.32
19 Hemoglobin Kenya, the product of fusion of amd polypeptide chains. Arch Biochem Biophys 1972 1.30
20 Homology requirements for unequal crossing over in humans. Genetics 1991 1.27
21 Fetal erythropoiesis following bone marrow transplantation. Blood 1976 1.26
22 Evidence for four nonallelic structural genes for the chain of human fetal hemoglobin. Biochem Genet 1972 1.23
23 Sickle cell anemia and trait in southern India: further studies. Am J Hematol 1979 1.20
24 Hemoglobin Richmond, a human hemoglobin which forms asymmetric hybrids with other hemoglobins. J Biol Chem 1969 1.20
25 Hemoglobin Kenya, the product of a gamma-beta fusion gene: studies of the family. Am J Hum Genet 1973 1.19
26 A new high-performance liquid chromatographic procedure to quantitate hemoglobin A1c and other minor hemoglobins in blood of normal, diabetic, and alcoholic individuals. J Lab Clin Med 1983 1.19
27 Two independent genetic factors in the beta-globin gene cluster are associated with high G gamma-levels in the HbF of SS patients. Blood 1984 1.18
28 Gamma thalassemia resulting from the deletion of a gamma-globin gene. Nucleic Acids Res 1983 1.18
29 Molecular analysis of the high-hemoglobin-F phenotype in Saudi Arabian sickle cell anemia. N Engl J Med 1987 1.17
30 Evidence for multiple structural genes for the gamma-chain of human fetal hemoglobin in hereditary persistence of fetal hemoglobin. Ann N Y Acad Sci 1969 1.17
31 A new high-performance liquid chromatographic procedure for the separation and quantitation of various hemoglobin variants in adults and newborn babies. J Lab Clin Med 1983 1.16
32 Beta-thalassemia in Turkey. Hemoglobin 1990 1.14
33 Gene deletion as the molecular basis for the Kenya-G gamma-HPFH condition. Hemoglobin 1983 1.13
34 Qualitative and quantitative studies of sickle cell hemoglobin in homozygotes and heterozygotes. Clin Chim Acta 1968 1.12
35 The heterogeneity of goat hemoglobin: evidence for the existence of two nonallelic and one allelic alpha chain structural genes. Arch Biochem Biophys 1967 1.11
36 Hereditary persistence of fetal hemoglobin or (delta beta)o-thalassemia: three types observed in South-Chinese families. Blood 1985 1.10
37 Access to a syllabus of human hemoglobin variants (1996) via the World Wide Web. Hemoglobin 1998 1.10
38 Microchromatography of hemoglobins. II. A rapid method for the determination of hemoglobin A2. J Lab Clin Med 1974 1.10
39 Heterogeneity in the molecular basis of three types of hereditary persistence of fetal hemoglobin and the relative synthesis of the G gamma and A gamma types of gamma chain. Biochem Genet 1984 1.09
40 Polymorphisms in the human haptoglobin gene cluster: chromosomes with multiple haptoglobin-related (Hpr) genes. Proc Natl Acad Sci U S A 1986 1.08
41 The production of hemoglobin C in sheep carrying the gene for hemoglobin A: hematologic aspects. Blood 1966 1.08
42 Inheritance of F cell frequency in heterocellular hereditary persistence of fetal hemoglobin: an example of allelic exclusion. Am J Hum Genet 1977 1.06
43 Minor hemoglobins in sickle cell anemia, beta-thalassemia, and related conditions: a study of red cell fractions isolated by density gradient centrifugation. Biochem Med 1975 1.06
44 The rare alpha-thalassemia-1 of blacks is a zeta alpha-thalassemia-1 associated with deletion of all alpha- and zeta-globin genes. Blood 1984 1.04
45 Hereditary persistence of fetal hemoglobin. Heterogeneity of fetal hemoglobin in homozygotes and in conjunction with -thalassemia. N Engl J Med 1971 1.03
46 Hemoglobin C in newborn sheep and goats: a possible explanation for its function and biosynthesis. Pediatr Res 1969 1.03
47 Hb Adana or alpha 2(59)(E8)Gly-->Asp beta 2, a severely unstable alpha 1-globin variant, observed in combination with the -(alpha)20.5 Kb alpha-thal-1 deletion in two Turkish patients. Am J Hematol 1993 1.02
48 The G----A mutation at position +22 3' to the Cap site of the beta-globin gene as a possible cause for a beta-thalassemia. Hemoglobin 1991 1.01
49 Two novel polyadenylation mutations leading to beta(+)-thalassemia. Br J Haematol 1990 1.01
50 alpha-Thalassaemia in the population of Cyprus. Br J Haematol 1995 1.01
51 Hemoglobin Louisville (beta-42 (CD1) phe-leu): an unstable variant causing mild hemolytic anemia. J Clin Invest 1971 1.01
52 Quantitation of hemoglobin components by high-performance cation-exchange liquid chromatography: its use in diagnosis and in the assessment of cellular distribution of hemoglobin variants. Am J Hematol 1984 1.00
53 Molecular packing and intermolecular contacts of sickling deer type III hemoglobin. J Mol Biol 1979 1.00
54 Upstream promoter mutation associated with a modest elevation of fetal hemoglobin expression in human adults. Blood 1988 0.99
55 Hemoglobin Grady: the first example of a variant with elongated chains due to an insertion of residues. Proc Natl Acad Sci U S A 1974 0.99
56 Pseudoautosomal repeat displays higher variability in blacks than in Caucasians. Hum Genet 1992 0.99
57 Hb H disease in a Turkish family resulting from the interaction of a deletional alpha-thalassaemia-1 and a newly discovered poly A mutation. Br J Haematol 1992 0.99
58 The chemical heterogeneity of the fetal hemoglobin in normal newborn infants and in adults. Mol Cell Biochem 1977 0.99
59 A homozygote for the Hb G type of foetal haemoglobin in India: a study of two Indian and four Negro families. Br J Haematol 1972 0.98
60 Normal and abnormal human hemoglobins. Adv Clin Chem 1972 0.98
61 Hemoglobin-Bibba or alpha-2-136Pro-beta 2, an unstable alpha chain abnormal hemoglobin. Biochim Biophys Acta 1968 0.98
62 -G gamma A gamma-Thalassemia and gamma-chain variants in Chinese newborn babies. Am J Hematol 1985 0.98
63 Observations on the levels of Hb A2 in patients with different beta-thalassemia mutations and a delta chain variant. Blood 1990 0.98
64 Molecular characterization of Hb S(C) beta-thalassemia in American blacks. Am J Hematol 1991 0.98
65 gamma-Globin gene triplication and quadruplication in Japanese newborns. Evidence for a decreased in vivo expression of the 3'-A gamma-globin gene. FEBS Lett 1985 0.97
66 Heterogeneity of fetal hemoglobin in beta-thalassemia of the Negro. Am J Hum Genet 1970 0.96
67 Detection of alpha-thalassemia-2 (-3.7 kb) and its corresponding triplication (alpha)(alpha)(alpha) (anti-3.7 kb) by PCR: an improved technical change. Am J Hematol 1996 0.96
68 Beta-thalassemia, HB S-beta-thalassemia and sickle cell anemia among Tunisians. Hemoglobin 1991 0.96
69 An A gamma type of nondeletional hereditary persistence of fetal hemoglobin with a T----C mutation at position -175 to the cap site of the A gamma globin gene. Blood 1989 0.96
70 Hb Grady and alpha thalassemia: a contribution to the problem of the number of Hb alpha structural loci in man. Am J Hum Genet 1976 0.95
71 The levels of zeta, gamma, and delta chains in patients with Hb H disease. Hum Genet 1989 0.95
72 Studies on the heterogeneity of hemoglobin. XIV. Chromatography of normal and abnormal human hemoglobin types on CM-Sephadex. J Chromatogr 1969 0.95
73 Analysis of hemoglobin F production in Saudi Arabian families with sickle cell anemia. Blood 1987 0.95
74 An electronic database of human hemoglobin variants on the World Wide Web. Blood 1998 0.95
75 An unusual hemoglobin anomaly and its relation to alpha-thalassemia and hemoglobin-H disease. J Clin Invest 1971 0.94
76 World-wide occurrence of nonallelic genes for the -chain of human foetal haemoglobin in newborns. Nat New Biol 1972 0.94
77 Trimodality in the percentages of beta chain variants in heterozygotes: the effect of the number of active Hbalpha structural loci. Hemoglobin 1977 0.94
78 Haplotypes of beta S chromosomes among patients with sickle cell anemia from Georgia. Hemoglobin 1986 0.94
79 Hemoglobin alpha chain deficiency in black children with variable quantities of hemoglobin Bart's at birth. Pediatr Res 1977 0.93
80 Changes in the haemoglobin types of sheep as a response to anaemia. Biochem J 1964 0.93
81 Two novel arrangements of the human fetal globin genes: G gamma-G gamma and A gamma-A gamma. Nucleic Acids Res 1984 0.93
82 Hydrops fetalis due to homozygosity for alpha-thalassemia-1, -(alpha)-20.5 kb: the first observation in a Turkish family. Acta Haematol 1989 0.93
83 Hemoglobin F in beta thalassemia and related conditions. Ann N Y Acad Sci 1980 0.93
84 Homozygous hemoglobin O Arab in a gypsy family in Yugoslavia. Hemoglobin 1977 0.93
85 A second type of hereditary persistence of foetal haemoglobin in India. Br J Haematol 1973 0.93
86 A G gamma type of the hereditary persistence of fetal hemoglobin with beta chain production in cis. Am J Hum Genet 1975 0.92
87 The differences in quantities of alpha 2- and alpha 1-globin gene variants in heterozygotes. Br J Haematol 1994 0.92
88 Quantitation of three types of gamma chain of HbF by high pressure liquid chromatography; application of this method to the HbF of patients with sickle cell anemia or the S-HPFH condition. Blood 1981 0.92
89 A mild type of Hb S-beta(+)-thalassemia [-92(C-->T)] in a Sicilian family. Am J Hematol 1993 0.92
90 Severe Hb S-beta zero-thalassaemia with a T----C substitution in the donor splice site of the first intron of the beta-globin gene. Br J Haematol 1989 0.92
91 Distal CCAAT box deletion in the A gamma globin gene of two black adolescents with elevated fetal A gamma globin. Nucleic Acids Res 1988 0.92
92 Molecular characterization of alpha-thalassemia determinants, beta-thalassemia alleles, and beta S haplotypes among Kuwaiti Arabs. Acta Haematol 1994 0.92
93 Quantitation of hemoglobin alpha chains in adult and fetal goats; gene duplication and the production of polypeptide chains. Arch Biochem Biophys 1969 0.91
94 The detection of beta-globin gene mutations in beta-thalassemia using oligonucleotide probes and amplified DNA. Biochim Biophys Acta 1988 0.91
95 Non-synchronized suppression of postnatal activity in non-allelic genes which synthesize the Ggamma chain in human foetal haemoglobin. Nat New Biol 1973 0.91
96 Nature of fetal hemoglobin in the Greek type of hereditary persistence of fetal hemoglobin with and without concurrent beta-thalassemia. J Clin Invest 1970 0.91
97 Alpha and beta thalassaemia among Chinese children in Guangxi Province, P.R. China: molecular and haematological characterization. Br J Haematol 1994 0.90
98 Anomaly in the gamma chain heterogeneity of the newborn. Nature 1977 0.90
99 Types of alpha-globin gene deficiencies in Chinese newborn babies in the Guangxi region, P. R. China. Hemoglobin 1992 0.90
100 Homozygous beta0- and beta+ - thalassemia in Kurdish Jews and Arabs. Hemoglobin 1977 0.90
101 Dutch beta 0-thalassaemia: a 10 kilobase DNA deletion associated with significant gamma-chain production. Br J Haematol 1984 0.90
102 The structure of goat hemoglobins. I. Structural studies of the beta chains of the hemoglobins of normal and anemic goats. J Biol Chem 1967 0.90
103 Polymorphic pattern of the (AT)X(T)Y motif at -530 5' to the beta-globin gene in over 40 patients homozygous for various beta-thalassemia mutations. Am J Hematol 1994 0.89
104 The ratio of the G gamma and A gamma chains: variations due to anomalies at the molecular level. Ann N Y Acad Sci 1985 0.89
105 The T gamma chain of human fetal hemoglobin at birth and in several abnormal hematologic conditions. Pediatr Res 1977 0.89
106 On the chromatographic heterogeneity of human fetal hemoglobin. Biochim Biophys Acta 1979 0.89
107 Hb Le Lamentin or alpha 2 20(B1)His----GLN beta 2 found in a Spanish family. Hemoglobin 1988 0.89
108 One form of inclusion body beta-thalassemia is due to a GAA----TAA mutation at codon 121 of the beta chain. Blood 1989 0.88
109 The relative levels of alpha 2-, alpha 1-, and zeta-mRNA in HB H patients with different deletional and nondeletional alpha-thalassemia determinants. Biochim Biophys Acta 1996 0.88
110 Hemoglobin Freiburg: abnormal hemoglobin due to deletion of a single amino acid residue. Science 1966 0.88
111 Nature of foetal haemoglobin in F-thalassaemia. Br J Haematol 1971 0.88
112 Chemical heterogeneity of fetal hemoglobin in subjects with sickle cell anemia, homozygous Hb-C disease, SC disease, and various combinations of hemoglobin variants. Clin Chim Acta 1972 0.87
113 Hb E and Hb E-like variants in individuals from Turkey. Hemoglobin 1981 0.87
114 A novel beta zero-thalassaemia mutation (codon 15, TGG----TGA) is prevalent in a population of central Portugal. Br J Haematol 1992 0.87
115 Molecular characterization of beta-thalassemia in north Jordan. Hemoglobin 1994 0.87
116 Hemoglobin Savannah (B6(24) beta-glycine is greater than valine): an unstable variant causing anemia with inclusion bodies. J Clin Invest 1971 0.87
117 A fetal hemoglobin with abnormal gamma-polypeptide chains: hemoglobin Warren. Blood 1965 0.87
118 The occurrence of different levels of G gamma chain and of the A gamma T variant of fetal hemoglobin in newborn babies from several countries. Am J Hematol 1983 0.87
119 Microchromatography of hemoglobins. IV. An improved procedure for the detection of hemoglobins S and C at birth. J Lab Clin Med 1975 0.87
120 The hemoglobin heterogeneity of the Virginia white-tailed deer: a possible genetic explanation. Arch Biochem Biophys 1968 0.87
121 The in vivo production of hemoglobin C in ruminants. Ann N Y Acad Sci 1974 0.87
122 Separation of normal and abnormal hemoglobin chains by reversed-phase high-performance liquid chromatography. J Chromatogr 1986 0.87
123 Search for nonallelic structural genes for gamma-chains of fetal hemoglobin in some primates. Biochem Genet 1973 0.86
124 A novel deletion of approximately 27 kb including the beta-globin gene and the locus control region 3'HS-1 regulatory sequence: beta zero-thalassemia or hereditary persistence of fetal hemoglobin? Blood 1994 0.86
125 The Ggamma deltabeta-thalassemia and Ggamma-betaO-hpfh conditions in combination with beta-thalassemia and Hb S. Am J Hematol 1977 0.86
126 Oxygen equilibria studies of the hemoglobins from normal and anemic sheep and goats. Am J Physiol 1968 0.86
127 Haplotypes and alpha globin gene analyses in sickle cell anaemia patients from Kenya. Br J Haematol 1987 0.86
128 The association of sickle cell anemia with heterozygous and homozygous alpha-thalassemia-2: in vitro HB chain synthesis. Am J Hematol 1979 0.85
129 Fetal hemoglobin in normal adults and beta-thalassemia heterozygotes. Hum Genet 1990 0.85
130 Molecular characterization of beta-globin gene mutations in Malay patients with Hb E-beta-thalassaemia and thalassaemia major. Br J Haematol 1989 0.85
131 The -158 (C-->T) promoter mutation is responsible for the increased transcription of the 3' gamma gene in the Atlanta type of hereditary persistence of fetal hemoglobin. Blood 1994 0.85
132 An adult homozygous for persistent fetal hemoglobin. Ann Intern Med 1970 0.85
133 Quantitative microchromatographic determination of hemoglobin F in patients with hemoglobins S and/or C. Am J Hematol 1976 0.85
134 Radioimmunoassay for abnormal hemoglobins. Science 1977 0.85
135 A second observation of the fetal methemoglobin variant Hb F-M-Fort Ripley or alpha 2G gamma 2(92)(F8)His----Tyr. Hemoglobin 1992 0.84
136 Beta-thalassemia due to a T----A mutation within the ATA box. Biochem Biophys Res Commun 1988 0.84
137 The Georgia type of nondeletional hereditary persistence of fetal hemoglobin has a C---T mutation at nucleotide-114 of the A gamma-globin gene. Blood 1991 0.84
138 Structural characterization of two delta chain variants. Hemoglobin A'-2 (B2) and hemoglobin Flatbush. J Biol Chem 1967 0.84
139 Organization of alpha-chain genes among Hb G-Philadelphia heterozygotes in association with Hb S, beta-thalassemia, and alpha-thalassemia-2. Biochem Genet 1982 0.84
140 Experiences with the quantitation of human hemoglobin types by high pressure liquid chromatography. Prog Clin Biol Res 1981 0.84
141 Hb Vaasa or alpha2beta2 (39(C5)Gln replaced by Glu), a mildly unstable variant found in a Finnish family. Hemoglobin 1977 0.84
142 Red cell 2,3-diphosphoglycerate and oxygen affinity in newborn goats and sheep. Proc Soc Exp Biol Med 1971 0.84
143 Inclusion body beta-thalassemia trait in a Swiss family is caused by an abnormal hemoglobin (Geneva) with an altered and extended beta chain carboxy-terminus due to a modification in codon beta 114. Blood 1988 0.84
144 Allele-specific amplification for the identification of several hemoglobin variants. Hemoglobin 1993 0.84
145 Gene structure in hereditary persistence of fetal hemoglobin individuals. Hemoglobin 1980 0.83
146 The Brazilian type of nondeletional A gamma-fetal hemoglobin has a C----G substitution at nucleotide -195 of the A gamma-globin gene. Blood 1990 0.83
147 (A gamma delta beta)0-Thalassaemia in Blacks is due to a deletion of 34 kbp of DNA. Br J Haematol 1985 0.83
148 alpha Chain and gamma chain abnormal hemoglobins in newborn babies: structural and genetic aspects. Am J Hematol 1983 0.83
149 Abnormal arrangements in the alpha- and gamma-globin gene clusters in a relatively large group of Japanese newborns. Am J Hum Genet 1986 0.83
150 An approximately 300 bp deletion involving part of the 5' beta-globin gene region is observed in members of a Turkish family with beta-thalassemia. Blood 1987 0.83
151 Hb Alesha or alpha 2 beta (2)67(E11)Val-->Met: a new unstable hemoglobin variant identified through sequencing of amplified DNA. Hemoglobin 1993 0.83
152 Identification of base substitutions in the promoter regions of the A gamma- and G gamma-globin genes in A gamma- (or G gamma-) beta+-HPFH heterozygotes using the DNA-amplification-synthetic oligonucleotide procedure. Blood 1988 0.83
153 Studies on the heterogeneity of hemoglobin. XI. Chromatographic studies of intermediate forms of oxy- and ferrihemoglobin. Arch Biochem Biophys 1966 0.83
154 Characterization of the beta+-thalassemia mutation in a homozygous Yugoslavian patient. Hemoglobin 1984 0.83
155 Separation of hemoglobins and hemoglobin chains by high-performance liquid chromatography. J Chromatogr 1987 0.83
156 Sequence variations in the 5' flanking and IVS-II regions of the G gamma- and A gamma-globin genes of beta S chromosomes with five different haplotypes. Blood 1991 0.83
157 Five adults with mild sickle cell anemia share a beta S chromosome with the same haplotype. Am J Hematol 1985 0.83
158 The DNA deletion in an Indian delta beta-thalassaemia begins one kilobase from the A gamma globin gene and ends in an L1 repetitive sequence. Br J Haematol 1989 0.83
159 International Hemoglobin Information Center variant list. Hemoglobin 1996 0.82
160 The occurrence and identification of alpha-thalassemia-2 among hemoglobin S heterozygotes. Am J Clin Pathol 1981 0.82
161 New aspects of the structure, function, and synthesis of hemoglobins. CRC Crit Rev Clin Lab Sci 1970 0.82
162 The chemical heterogeneity of the fetal hemoglobin of black newborn babies and adults: a reevaluation. Blood 1981 0.82
163 The beta-delta crossover leading to the beta delta hybrid gene of hemoglobin P-Nilotic is located within 54 base-pairs of the 5' end of exon 2 or between codons 31 and 50. Biochim Biophys Acta 1987 0.82
164 The use of globin chain electrophoresis in polyacrylamide gels for the quantitation of the G gamma to A gamma ratio in fetal hemoglobin. Hemoglobin 1981 0.82
165 Hb Evans or alpha 262(E11)Val----Met beta 2; an unstable hemoglobin causing a mild hemolytic anemia. Hemoglobin 1989 0.82
166 Studies of the proporation and synthesis of haemoblogin C Philadelphia in red cells of heterozygotes, a homozygote, and a heterozygote for both haemoglobin G and alpha thalassaemia. Br J Haematol 1976 0.82
167 Homozygosity for a new type of G gamma (A gamma delta beta)zero-thalassemia in a Malaysian male. Hemoglobin 1986 0.82
168 First observation of hemoglobin J Paris I [alpha-2-12(A10)alanine-aspartic acid beta-2] in the Indian subcontinent. Acta Haematol 1988 0.82
169 Subunit dissociation of the abnormal hemoglobins G Georgia ( 2 95Leu (G2) 2 ) and Rampa ( 2 95Ser (G2) 2 ). J Biol Chem 1972 0.82
170 Sequence variations in the 5' hypersensitive site-2 of the locus control region of beta S chromosomes are associated with different levels of fetal globin in hemoglobin S homozygotes. Blood 1992 0.82
171 Partial deletion of the 5' beta-globin gene region causes beta zero-thalassemia in members of an American black family. Blood 1984 0.82
172 Hb Tigraye or alpha 2 beta (2)79(EF3)Asp-->His(GAC-->CAC): a hemoglobin variant with increased oxygen affinity observed in an Ethiopian male. Hemoglobin 1993 0.82
173 Two different theta (theta) globin gene deletions observed among black newborn babies. Br J Haematol 1988 0.82
174 Recent advances in the quantitation of human fetal hemoglobins with different gamma chains. Am J Hematol 1980 0.82
175 Homozygotes for the hereditary persistence of fetal hemoglobin: the ratio of G gamma to A gamma chains and biosynthetic studies. Biochem Genet 1977 0.82
176 Delta beta-thalassemia in a Mexican family: clinical differences among homozygotes. Hemoglobin 1978 0.82
177 The influence of antiserum to human erythropoietin on the production of hemoglobin C in goats. Proc Soc Exp Biol Med 1970 0.81
178 Molecular characterization of beta-thalassemia in Azerbaijan. Hum Genet 1992 0.81
179 A large beta-thalassemia deletion in a family of Indonesian-Malay descent. Hemoglobin 1996 0.81
180 On the quaternary structure of hemoglobin A-Ic. Biochim Biophys Acta 1969 0.81
181 A C----G mutation at nt position 6 3' to the terminating codon may be the cause of a silent beta-thalassemia. Int J Hematol 1991 0.81
182 Analysis of mRNA from red cells of patients with thalassemia and hemoglobin variants. Hemoglobin 1997 0.81
183 Hemoglobin O-Padova or alpha(2)30(B11)Glu----Lys beta 2 observed in members of a Turkish family. Hemoglobin 1985 0.81
184 Further studies of the frequency and significance of the Tgamma-chain of human fetal hemoglobin. J Clin Invest 1979 0.81
185 A possible subclass of the hereditary persistence of fetal hemoglobin. Blood 1970 0.81
186 Clinical, hematological, and molecular features in Sicilians with Hb S-beta-thalassemia. Am J Hematol 1992 0.81
187 Hb Saint Louis or alpha 2 beta 2(28)(B10)Leu----Gln in a Czechoslovakian male. Hemoglobin 1986 0.81
188 Low pulse oximeter-measured hemoglobin oxygen saturations with hemoglobin Cheverly. Am J Hematol 1998 0.81
189 One haplotype is associated with the Swiss type of hereditary persistence of fetal hemoglobin in the Yugoslavian population. Hum Genet 1987 0.81
190 Mechanism of sickling in deer erythrocytes. Ann N Y Acad Sci 1974 0.81
191 Different zeta globin gene deletions among black Americans. Hum Genet 1986 0.81
192 Hemoglobin Hamadan or alpha 2 beta 256(D7)Gly----Arg in a Turkish family. Hemoglobin 1984 0.81
193 Hb Himeji or alpha 2 beta 2(140)(H18)Ala----Asp in a Portuguese family. Hemoglobin 1989 0.81
194 Characterization of chromosomes with hybrid genes for Hb Lepore-Washington, Hb Lepore-Baltimore, Hb P-Nilotic, and Hb Kenya. Hum Genet 1987 0.80
195 Sickle cell anaemia among Eti-Turks: haematological, clinical and genetic observations. Br J Haematol 1986 0.80
196 Sickle cell anemia, sickle cell beta-thalassemia, and thalassemia major in Albania: characterization of mutations. Hum Genet 1994 0.80
197 Hemoglobin-A2-Coburg or alpha2delta2116Arg leads to His (G18). Biochim Biophys Acta 1975 0.80
198 Hb F-M-Osaka or alpha 2G gamma 2(63)(E7)His----Tyr in a Caucasian male infant. Hemoglobin 1989 0.80
199 The V gamma chain of fetal hemoglobin of the orangutan. Biochem Genet 1978 0.80
200 Chinese in west Malaysia: the geography of beta thalassaemia mutations. Singapore Med J 1990 0.80
201 A de novo deletion causing epsilon gamma delta beta-thalassemia in a Dutch patient. Acta Haematol 1996 0.80
202 Four categories of gamma-globin gene triplications: DNA sequence comparison of low G gamma and high G gamma triplications. Blood 1988 0.80
203 Delta Beta-Thalassaemia in two yugoslavian families. Scand J Haematol 1975 0.80
204 Two arrangements of the human fetal globin genes may be responsible for high G gamma values in Chinese newborns: -G gamma-G gamma-delta-beta and -G gamma-A gamma G gamma-A gamma-delta-beta. Am J Hematol 1985 0.80
205 gamma-mRNA and Hb F levels in beta-thalassaemia. Br J Haematol 1994 0.80
206 Another form of the hereditary persistence of fetal hemoglobin (the Atlanta type)? Hemoglobin 1977 0.80
207 Heterozygosity for the IVS-I-5 (G-->C) mutation with a G-->A change at codon 18 (Val-->Met; Hb Baden) in cis and a T-->G mutation at codon 126 (Val-->Gly; Hb Dhonburi) in trans resulting in a thalassemia intermedia. Biochim Biophys Acta 1992 0.80
208 Minor hemoglobins in sickle-cell heterozygotes and homozygotes with and without diabetes. Biochim Biophys Acta 1980 0.80
209 Electronic access to sequence alignments, experimental results, and human mutations as an aid to studying globin gene regulation. Genomics 1998 0.80
210 HB F-Yamaguchi (gamma 75Thr, gamma 80Asn, gamma 136Ala) is associated with G gamma-thalassemia. Am J Hematol 1984 0.79
211 A G to A nucleotide substitution 161 base pairs 5' of the G gamma globin gene cap site (-161) in a high G gamma non-anemic person. Prog Clin Biol Res 1987 0.79
212 Beta-thalassemia intermedia in two Turkish families is caused by the interaction of Hb Knossos [beta 27(B9)Ala----Ser] and of Hb City of Hope [beta 69(E13)Gly----ser] with beta (0)-thalassemia. Hemoglobin 1989 0.79
213 Amino acid sequences in the -chains of adult bovine hemoglobins C-Rhodesia and D-Zambia. Arch Biochem Biophys 1972 0.79
214 Rapid cation-exchange high-performance liquid chromatographic procedure for the separation and quantitation of hemoglobins S, C, and O Arab in cord blood samples. J Lab Clin Med 1986 0.79
215 The characterization of hemoglobin Manitoba or alpha (2)102(G9)Ser----Arg beta 2 and hemoglobin Contaldo or alpha (2)103(G10)His----Arg beta 2 by high performance liquid chromatography. Hemoglobin 1984 0.79
216 The heterogeneity of the fetal hemoglobin of the goat. Biochim Biophys Acta 1969 0.79
217 Molecular characterization of beta-thalassemia in Hungary. Hum Genet 1993 0.79
218 Differences in affinity of variant beta chains for alpha chains: a possible explanation for the variation in the percentages of beta chain variants in heterozygotes. Hemoglobin 1977 0.79
219 Beta-thalassemia mutations in the Portuguese; high frequencies of two alleles in restricted populations. Hemoglobin 1993 0.79
220 IV. The chemical heterogeneity of the chain from human fetal hemoglobin. CRC Crit Rev Clin Lab Sci 1970 0.79
221 Reverse dot-blot detection of the African-American beta-thalassemia mutations. Blood 1995 0.79
222 Hb Icaria-Hb H disease: identification of the Hb Icaria mutation through analysis of amplified DNA. Br J Haematol 1990 0.79
223 A novel alpha-thalassemia-2 (-2.7-kb) observed in a Chinese patient with Hb H disease. Am J Hematol 1991 0.79
224 The amino acid sequence of the delta-beta chains of hemoglobin Lepore Augusta = Lepore Washington. Biochim Biophys Acta 1966 0.79
225 Certain mutations observed in the 5' sequences of the G gamma- and A gamma-globin genes of beta S chromosomes are specific for chromosomes with major haplotypes. Acta Haematol 1991 0.79
226 Hb-J-Georgia=Hb-J-Baltimore= 2 2 16 Gly leads to Asp. Clin Chim Acta 1971 0.79
227 Five haplotypes in Black beta-thalassaemia heterozygotes: three are associated with high and two with low G gamma values in fetal haemoglobin. Br J Haematol 1985 0.79
228 Hydroxyurea therapy in sickle cell anemia patients in Curaçao, The Netherlands Antilles. Acta Haematol 1997 0.79
229 High frequencies of a rearrangement (+ATA; -T) at -530 to the beta-globin gene in different populations indicate the absence of a correlation with a silent beta-thalassemia determinant. Hemoglobin 1989 0.79
230 First observation of haemoglobin Malay alpha 2B2 26 (B1) Asn----Ser--a case report. Med J Malaysia 1989 0.79
231 Chromatographic separation of hemoglobins A 2 and C. The quantities of hemoglobin A 2 in patients with AC trait, CC disease, and C- -thalassemia. Clin Chim Acta 1972 0.79
232 The heterogeneity of the gamma-chain of fetal hemoglobin in HbS heterozygotes. Blood 1982 0.79
233 Hemoglobin Istanbul: substitution of glutamine for histidine in a proximal histidine (F8(92) ). J Clin Invest 1972 0.78
234 A new variant, HB Muscat [alpha 2 beta (2)32(B14)Leu----Val] observed in association with HB S in an Arabian family. Hemoglobin 1992 0.78
235 The structure of goat hemoglobins. IV. A third beta chain variant (betaE) with three apparent amino acid substitutions. Arch Biochem Biophys 1970 0.78
236 Detection and quantitation of the fetal hemoglobin variant Hb F-Malta-I in adults. Biochem Genet 1977 0.78
237 Hematological observations on Arabian SS patients with a homozygosity or heterozygosity for a beta S chromosome with haplotype #31. Hemoglobin 1985 0.78
238 Hb Costa Rica or alpha 2 beta 2 77(EF1)His --> Arg: the first example of a somatic cell mutation in a globin gene. Hum Genet 1996 0.78
239 Hemoglobin St Luke's, or alpha 2 , 95 Arg (G2) beta 2 . Eur J Biochem 1972 0.78
240 Hb F-La Grange or alpha 2 gamma 2 101(G3)Glu----Lys; 75Ile; 136Gly: a high oxygen affinity fetal hemoglobin variant observed in a Caucasian newborn. Biochim Biophys Acta 1984 0.78
241 Haplotypes among Vietnamese hemoglobin E homozygotes including one with a gamma-globin gene triplication. Am J Hum Genet 1986 0.78
242 The synthesis of the G gamma and A gamma chains of human fetal hemoglobin in erythroid colonies cultured from peripheral blood BFUe's of normal adults and newborn and of subjects with an A gamma or a G gamma chain abnormal fetal hemoglobin. Am J Hematol 1980 0.78
243 Subunit dissociation of the unstable hemoglobin Bibba (alpha 2-136Pro(H19)beta 2). J Biol Chem 1970 0.78
244 An initiation codon mutation as a cause of a beta-thalassemia. Hemoglobin 1990 0.78
245 Hb H disease caused by a homozygosity for the AATAAA-->AATAAG mutation in the polyadenylation site of the alpha 2-globin gene: hematological observations. Acta Haematol 1992 0.78
246 Compound heterozygosity for a beta zero-thalassemia (frameshift codons 38/39; -C) and a nondeletional Swiss type of HPFH (A----C at NT -110, G gamma) in a Czechoslovakian family. Ann Hematol 1991 0.78
247 Radioimmunochemical characterization of hemoglobins Lepore and Kenya: unique antigenic determinants located on hybrid hemoglobins. J Immunol 1978 0.78
248 Sickle cell anemia as a syndrome: a review of diagnostic features. Am J Hematol 1979 0.78
249 Dominant beta-thalassaemia trait in a Portuguese family is caused by a deletion of (G)TGGCTGGTGT(G) and an insertion of (G)GCAG(G) in codons 134, 135, 136 and 137 of the beta-globin gene. Br J Haematol 1991 0.78
250 Hemoglobin H disease in two Turkish females and one Iranian newborn. Hemoglobin 1985 0.78
251 Hb Setif or alpha 2 94(G1)Asp----Tyr beta 2 observed in a Saudi Arabian family. Hemoglobin 1985 0.78
252 Hb Wayne, the frameshift variant with extended alpha chains observed in a Caucasian family from Alabama. Hemoglobin 1984 0.78
253 Hemoglobin A2-Indonesia or alpha 2 delta 2 69(E13) Gly--Arg. Biochim Biophys Acta 1971 0.78
254 Clinical and hematological evaluation of two delta 0 beta 0-thalassemia homozygotes. Hemoglobin 1981 0.78
255 Hb Graz or alpha 2 beta 2(2)(NA2)His-->Leu; a new beta chain variant observed in four families from southern Austria. Hemoglobin 1992 0.78
256 Variability in the fetal hemoglobin level of the normal adult. Am J Hematol 1996 0.78
257 Recombinant hemoglobin variants. Hemoglobin 1998 0.78
258 Specific radioimmunochemical identification and quantitation of hemoglobins A2 and F. Am J Hematol 1976 0.78
259 Hb F-Dammam or alpha 2A gamma 2(79) (EF3) Asp----Asn. Hemoglobin 1985 0.78
260 Hemoglobin Russ or alpha-2-51-arg-beta-2. Biochim Biophys Acta 1966 0.78
261 Variation in the level of fetal hemoglobin in (delta beta) (0)-thalassemia heterozygotes with different numbers of alpha-globin genes. Am J Hematol 1990 0.78
262 The production of haemoglobin C in adult sheep and goats. Aust J Exp Biol Med Sci 1969 0.78
263 Hb Monroe or alpha 2 beta 230(B12)Arg----Thr, a variant associated with beta-thalassemia due to A G----C substitution adjacent to the donor splice site of the first intron. Hemoglobin 1989 0.78
264 The structure of goat hemoglobins. II. Structural studies of the alpha chains of the hemoglobins A and B. J Biol Chem 1968 0.78
265 Hb Leslie, an unstable hemoglobin due to deletion of glutaminyl residue beta 131 (H9) occurring in association with beta0-thalassemia, HbC, and HbS. Blood 1976 0.78
266 Hb Las Palmas or alpha 2 beta 2(49)(CD8)Ser----Phe, a mildly unstable hemoglobin variant. Hemoglobin 1988 0.78
267 Hemoglobin D-beta (0) thalassemia. A case report and family study. Am J Pediatr Hematol Oncol 1988 0.77
268 Biosynthetic and structural studies of hemoglobin in a patient with congenital dyserythropoietic anemia type I. Hemoglobin 1977 0.77
269 Hb F-Tokyo or alpha 2G gamma 2 34(B16)Val----Ile, a silent gamma chain variant detected by reverse phase high performance liquid chromatography. Hemoglobin 1985 0.77
270 Hemoglobin abnormalities in a black family with HB S, hereditary persistence of HB F, and a gamma chain variant; a reevaluation through gene mapping. Hemoglobin 1984 0.77
271 Alpha-, beta-, and gamma-mRNA levels in beta-thalassemia; transcriptional and translational differences in heterozygotes, homozygotes, and compound heterozygotes. Hemoglobin 1997 0.77
272 Comparison of the relative quantities of gamma-mRNAs and fetal hemoglobin in SS patients with different haplotypes. Acta Haematol 1998 0.77
273 Haplotypes and levels of fetal hemoglobin and G gamma to A gamma ratios in Mediterranean patients with thalassemia minor and major. Am J Hematol 1985 0.77
274 Hb-Alberta or alpha2beta2 (101(G3) Glu replaced by Gly), a new high-oxygen-affinity hemoglobin variant causing erythrocytosis. Hemoglobin 1977 0.77
275 Identification and quantitation of Hb Olympia [beta 20(B2)Val leads to Met] and Hb San Diego [beta 109(G11)Val leads to Met] by high-performance liquid chromatography. J Chromatogr 1983 0.77
276 Hb A2-Canada or alpha 2 delta 2 99(G1) Asp replaced by Asn, a newly discovered delta chain variant with increased oxygen affinity occurring in cis to beta-thalassemia. Hemoglobin 1982 0.77
277 The M gamma chain of human fetal hemoglobin is an A gamma chain with an in vitro modification of gamma 141 leucine to hydroxyleucine. J Chromatogr 1993 0.77
278 Hemoglobin G Georgia or alpha 2-95 Leu (G-2) beta-2. Biochim Biophys Acta 1970 0.77
279 Haplotypes in SS patients from Nigeria; characterization of one atypical beta S haplotype no. 19 (Benin) associated with elevated HB F and high G gamma levels. Ann Hematol 1992 0.77
280 An individual with "Miyada"-like hemoglobin indistinguishable from hemoglobin A2. Biochem Genet 1973 0.77
281 Hemoglobinopathies among the Gond tribal groups of central India; interaction of alpha- and beta-thalassemia with beta chain variants. Hemoglobin 1991 0.77
282 Hb Hekinan observed in three Chinese from Macau; identification of the GAG----GAT mutation in the alpha 1-globin gene. Hemoglobin 1990 0.77
283 On the levels of hemoglobins F and A2 in sickle-cell anemia and some related disorders. Am J Clin Pathol 1974 0.77
284 The separation of human hemoglobin chains by high pressure liquid chromatography. Prog Clin Biol Res 1981 0.77
285 Some properties of hemoglobin Gun Hill. Hemoglobin 1977 0.77
286 Analysis of high fetal hemoglobin production in sickle cell anemia patients from the Eastern Province of Saudi Arabia. Prog Clin Biol Res 1987 0.77
287 Separation of tryptic peptides of normal and abnormal alpha, beta, gamma, and delta hemoglobin chains by high-performance liquid chromatography. J Chromatogr 1979 0.77
288 Alternate organization of alpha G-Philadelphia globin genes among U.S. black and Italian Caucasian heterozygotes. Hemoglobin 1984 0.77
289 Hemoglobin Handsworth or alpha2 18(A16)Gly----Arg beta2 in a Saudi newborn. Hemoglobin 1985 0.77
290 Hb Coimbra or alpha 2 beta (2)99(G1)Asp----Glu, a newly discovered highoxygen affinity variant. Hemoglobin 1991 0.77
291 Hemoglobin Atlanta or alpha 2 beta 2 75 Leu-Pro (E19): an unstable variant found in several members of a Caucasian family. Biochim Biophys Acta 1975 0.77
292 Differences between the levels of G gamma chain in the fetal hemoglobin in two types of hereditary persistence of fetal hemoglobin are linked with a variation in the DNA sequence. Biochem Genet 1986 0.77
293 The relative levels of beta A and beta S mRNAs in Hb S heterozygotes and in patients with Hb S-beta(+)-thalassaemia or Hb S-beta(+)-HPFH combinations. Br J Haematol 1994 0.77
294 A Canadian family with Hb Wayne; characterization by HPLC and DNA sequencing. Hemoglobin 1992 0.77
295 Some notes about Hb Q-India and Hb Q-Iran. Hemoglobin 1986 0.76
296 The types of hemoglobins and globin chains in hydrops fetalis. Hemoglobin 1989 0.76
297 Nonallelic structural genes and hemoglobin synthesis. Hamatol Bluttransfus 1970 0.76
298 Hb Camden and Hb Hope found during routine testing. Acta Haematol 1975 0.76
299 Two different quadruplicated alpha globin gene arrangements. Br J Haematol 1987 0.76
300 Hb Chiapas alpha 2 114 Pro replaced by Arg beta 2: identification by high pressure liquid chromatography. Hemoglobin 1981 0.76
301 Adult and fetal hemoglobin production in erythroid colonies from subjects with beta-thalassemia or with hereditary persistance of fetal hemoglobin (HPFH). Hemoglobin 1980 0.76
302 Genetic heterogeneity of beta-thalassemia in southeast Sicily. Am J Hematol 1995 0.76
303 Hemoglobin Jenkins or hemoglobin-N-Baltimore or alpha-2-beta-2 95Glu. Biochim Biophys Acta 1966 0.76
304 The human fetal hemoglobins. Tex Rep Biol Med 1982 0.76
305 The synthesis of fetal hemoglobin types in red blood cells and in BFU-E derived colonies from peripheral blood of patients with sickle cell anemia, beta+ - and delta beta-thalassemia, various forms of hereditary persistence of fetal hemoglobin, normal adults and newborn. Hemoglobin 1979 0.76
306 Hb Winnipeg or alpha 2 75(EF4)Asp leads to Tyr beta 2 in a large Caucasian family living in Georgia, USA. Hemoglobin 1983 0.76
307 Hemoglobin Montreal: a new variant with an extended beta chain due to a deletion of Asp, Gly, Leu at positions 73, 74, and 75, and an insertion of Ala, Arg, Cys, Gln at the same location. Blood 1991 0.76
308 Level of fetal hemoglobin in children with sickle cell anemia: influence of gender, haplotype and alpha-thalassemia-2 trait. Acta Haematol 1993 0.76
309 Alpha-Thalassemia and fetal hemoglobin. Blood 1994 0.76
310 The dominant beta-thalassaemia in a Spanish family is due to a frameshift that introduces an extra CGG codon ( = arginine) at the 5' end of the second exon. Br J Haematol 1996 0.76
311 New ultra-micro high-performance liquid chromatographic method for determining the gamma chain composition of hemoglobin F in normal adults. J Chromatogr 1993 0.76
312 A new beta zero-thalassaemia nonsense mutation (codon 112, T-->A) not associated with a dominant type of thalassaemia in the heterozygote. Br J Haematol 1993 0.76
313 A new alpha-thalassemia-2 deletion resulting in microcytosis and hypochromia and in vitro chain imbalance in the heterozygote. Am J Hematol 1993 0.76
314 Hb Wuming or alpha 2 11(A9)Lys substituting for Gln beta 2. Hemoglobin 1981 0.76
315 Sheep hemoglobin D, an alpha-chain variant with one apparent amino acid substutution (alpha 15 Gly--Asp). Biochim Biophys Acta 1968 0.76
316 Hemoglobin Köln in a black: pre- and post-splenectomy red cell survival (DF32P and 51Cr) and the pathogenesis of hemoglobin instability. Blood 1973 0.76
317 Hb Iowa or alpha 2 beta 2(119)(GH2)Gly----Ala. Hemoglobin 1990 0.76
318 The G gamma T chain (G gamma 75 Thr; 136 Gly) in Hb F-Charlotte is the product of an A gamma gene with a limited gene conversion and that in Hb F-Waynesboro of a mutated G gamma gene. Hemoglobin 1995 0.76
319 Molecular characterization of beta-thalassaemia in 174 Greek patients with thalassaemia major. Br J Haematol 1990 0.76
320 Frameshift codon 5 [Fsc-5 (-CT)] thalassemia; a novel mutation detected in a Greek patient. Hemoglobin 1989 0.76
321 Hb Bab-Saadoun or alpha 2 beta (2)48(CD7)Leu----Pro, a mildly unstable variant found in an Arabian boy from Tunisia. Hemoglobin 1992 0.76
322 An individual with Hb-Lepore-Baltimore- delta beta-thalassaemia in a Yugoslavian family. Scand J Haematol 1976 0.76
323 A chromosome with five gamma-globin genes. Blood 1988 0.76
324 Haemoglobin Hammersmith precludes monitoring with conventional pulse oximetry. Can J Anaesth 1994 0.76
325 Hb H disease and mild mental retardation in a black girl with a Hb S heterozygosity. Hemoglobin 1992 0.75
326 Thalassemia in southern India. Interaction of genes for beta+-, beta o-, and delta o beta o-thalassemia. Acta Haematol 1980 0.75
327 Hb Sun Prairie or alpha(2)130(H13)Ala----Pro beta 2; second observation in an Indian adult. Hemoglobin 1990 0.75
328 The Atlanta family with hemoglobin Grady revisited. Am J Hum Genet 1983 0.75
329 Hb P-Nilotic in association with beta0-thalassemia: cis-mutation of a hemoglobin betaA chain regulatory determinant? J Lab Clin Med 1979 0.75
330 Hemoglobin-Strumica or alpha 2 112(G19) His replaced by Arg beta 2. (With an addendum: hemoglobin-J-Paris-I, alpha 2 12(A10) Ala replaced by Asp beta 2, in the same population). Biochim Biophys Acta 1975 0.75
331 Incorrect genetic counseling of a couple with beta-thalassemia, due to incomplete testing. Am J Hum Genet 1993 0.75
332 A note on the inheritance of the hereditary persistence of fetal haemoglobin and the delta-chain variant Hb-A2'. J Med Genet 1976 0.75
333 Hemoglobin Queens (alpha 34 (B15) Leu replaced by Arg) found in two Chinese families. Hemoglobin 1982 0.75
334 Hb A2-Babinga, Hb S, and HPFH in members of a family from Creola, Alabama. Hemoglobin 1984 0.75
335 Hb Lepore Washington-Boston in two Mexican mestizo families. Rev Invest Clin 1997 0.75
336 Application of high-performance liquid chromatographic methodology to the analysis of hemoglobins synthesized in erythroid progenitor cells. J Chromatogr 1989 0.75
337 The frequency of the gamma chain variant A gamma T in different populations, and its use in evaluating gamma gene expression in association with thalassemia. Hum Genet 1985 0.75
338 Two rare hemoglobin variants: Hb Pyrgos [beta 83(EF7)Gly-->Asp] and Hb Legnano [alpha 141(Hc3)Arg-->Leu] found in Inner Mongolia, P. R. China. Hemoglobin 1994 0.75
339 Persistent iron and folate deficiency in a patient with deletional hereditary persistence of fetal hemoglobin; the effect on the relative levels of Hb F and G gamma chains and the corresponding mRNAs. Hemoglobin 1998 0.75
340 Hb Nunobiki or alpha 2 141 (HC3)Arg-->Cys beta 2 in a Belgian female results from a CGT-->TGT mutation in the alpha 2-globin gene. Hemoglobin 1996 0.75
341 Construction of two plasmids, each containing three different human globin gene fragments. Hemoglobin 1987 0.75
342 Post-translational control of human hemoglobin synthesis; the number of alpha chain genes and the synthesis of HB S. Prog Clin Biol Res 1978 0.75
343 The linkage of Hb Valletta [alpha 2 beta 287(f3)Thr----Pro] and Hb F-Malta-I [alpha 2G gamma 2117(G19)His----Arg] in the Maltese population. Hum Genet 1991 0.75
344 Synthesis of the minor fetal hemoglobin Fic in colonies of erythropoietic precursors isolated from human umbilical cord blood. Am J Hematol 1982 0.75
345 I. Alteration in the properties of human hemoglobin A by variation in structure: a correlation of structure and function. CRC Crit Rev Clin Lab Sci 1970 0.75
346 HB Chicago or alpha (2)136 (H19) Leu----Met beta 2 and a -G gamma-G gamma-globin gene arrangement in a black family. Hemoglobin 1986 0.75
347 Characterization of a newly discovered alpha-thalassaemia-1 in two Spanish patients with Hb H disease. Br J Haematol 1988 0.75
348 Identification of several alpha-globin gene variations in a small Laotian family. Acta Haematol 1995 0.75
349 Synthesis of a fixed-length single-stranded DNA probe by blocking primer extension in bacteriophage M13. Gene 1986 0.75
350 Hemoglobin-Q-India (64 (E13) Asp-His) and beta thalassemia: a case report from Punjab (North India) Eur J Haematol 1988 0.75
351 Frequency of the alpha-thalassemia-2 gene among Nigerian SS patients and its influence on malaria antibody titers. Hemoglobin 1993 0.75
352 Hb S, Hb G-Philadelphia and alpha-thalassemia-2 in a Black family. Pediatr Res 1980 0.75
353 Hb F-Kingston or alpha 2G gamma 2(55)(D6)Met----Arg in a Spanish newborn. Hemoglobin 1987 0.75
354 II. Binding of organic phosphates to hemoglobin. CRC Crit Rev Clin Lab Sci 1970 0.75
355 Haemoglobins D-Los Angeles (alpha2beta2 121 GLU leads to GLN) and J-Baltimore (alpha2beta2 16 GLY leads to ASP) in two Dutch families. Neth J Med 1975 0.75
356 Hb J-Singa (alpha-78 Asn leads to Asp), a newly discovered hemoglobin variant with the same amino acid substitution as one of the two present in Hb J-Singapore (alpha-78 Asn leads to, alpha-79 Ala leads to Gly). Biochim Biophys Acta 1984 0.75
357 A newly discovered beta O-thalassemia (IVS-II-850, G-->A) mutation in a north European family. Hemoglobin 1995 0.75
358 Hb Fort Worth or alpha2 27(B8)Glu----Gly beta2 in a black family from Canada. Hemoglobin 1985 0.75
359 Variation in clinical severity among patients with Hb Lepore-Boston-beta-thalassaemia is related to the type of beta-thalassaemia. Br J Haematol 1988 0.75
360 The relative levels of different types of beta-mRNA and beta-globin in BFU-E derived colonies from patients with beta chain variants; further evidence for somatic mosaicism in the Hb Costa Rica carrier [beta 77(EF1)His-->Arg]. Hemoglobin 1996 0.75
361 Isobutyramide therapy in patients with sickle cell anemia. Am J Hematol 1995 0.75
362 The importance of the 3' untranslated region for the expression of the alpha-globin genes. Hemoglobin 1996 0.75
363 Two new large deletions resulting in epsilon gamma delta beta-thalassemia. Acta Haematol 1988 0.75
364 Newer developments in the identification of beta-thalassemia. Hemoglobin 1988 0.75
365 Hb Bibba or alpha 2 136(H19)Leu-->Pro beta 2 in a Caucasian family from Alabama. Hemoglobin 1995 0.75
366 Fetal hemoglobin variants identified in adults through restriction endonuclease gene mapping methodology. Blood 1985 0.75
367 Nucleotide sequence of the human theta 1-globin gene. Biochem Genet 1988 0.75
368 Hb Leslie is the same as Hb Shelby or alpha 2 beta 2 131 (H9)Gln----Lys. Hemoglobin 1984 0.75
369 Possible relationship between the level of Hb Bart's (gamma4) and the relative amount of Hb S or Hb C in black heterozygous newborn. Hemoglobin 1978 0.75
370 alpha-Thalassemia and beta-thalassemia in a Turkish family. Am J Hematol 1977 0.75
371 Hb F-Austell or alpha 2G gamma (2)40(C6)Arg----Lys. Hemoglobin 1988 0.75
372 Hb N-Baltimore [alpha 2 beta 2(95)(FG2)Lys----Glu] and Hb J-Iran [alpha 2 beta 2(77)(Ef1]His----Asp] observed in a Turkish family from Antalya. Hemoglobin 1990 0.75
373 Minor hemoglobins (Hb AI) in chronic alcoholic patients. Hemoglobin 1982 0.75
374 Hb Gainesville-GA or alpha 2 beta 2 46(CD5)Gly----Arg. Hemoglobin 1985 0.75
375 Hb Bicêtre or alpha 2 beta(2)63(E7)His----Pro in a white male: clinical observations over a period of 25 years. Am J Hematol 1986 0.75
376 The characterization of variants of human hemoglobin A2. Clin Chim Acta 1974 0.75
377 Hb Brockton [alpha 2 beta 2138(H16)Ala----Pro] observed in a Turkish girl. Hemoglobin 1989 0.75
378 An X-ray determination of the molecular interactions in hemoglobin C: a disease characterized by intraerythrocytic crystals. Biochem Biophys Res Commun 1979 0.75
379 Hb Oleander, alpha 116(GH4)GLU----GLN, found in a Black female in Georgia. Hemoglobin 1984 0.75
380 Hemoglobin Beograd or alpha 2 beta 2 121 Glu-Val (GH4). Biochim Biophys Acta 1973 0.75
381 A second patient with hemoglobin Alberta, a high-oxygen-affinity variant causing erythrocytosis and forming asymmetric tetramers. Hemoglobin 1978 0.75
382 HB ottawa [alpha 15 (A13) GLY----ARG] found in Hubei Province, People's Republic of China. J Tongji Med Univ 1986 0.75
383 The hemoglobin P-Galveston-Hb-C conduction in members of a black family from South Carolina. FEBS Lett 1978 0.75
384 A new slow-moving hemoglobin variant Hb Tianshui or alpha 2 beta(2)39(C5)Gln----Arg, observed in a Chinese family living in Gansu. Hemoglobin 1990 0.75
385 Hb Chad or alpha 223(B4)Glu----Lys beta 2 observed in members of a Surinam family in association with alpha-thalassemia-2 and with Hb S. Hemoglobin 1989 0.75
386 Hb Sögn or alpha 2 beta 2 14(A11)Leu-->Arg in combination with an alpha-thalassemia heterozygosity. Hemoglobin 1996 0.75
387 The 18- to 23-kb deletion of the Macedonian delta beta-thalassemia includes the entire delta and beta globin genes. Blood 1986 0.75
388 The ratio of G gamma and A gamma chains of the hemoglobin F synthesized by BFU-E-derived colonies from blood of subjects with beta+ thalassemia and related hemoglobinopathies. Ann N Y Acad Sci 1980 0.75
389 Hb F in sickle cell anemia. Experientia 1993 0.75
390 The M gamma chain of human fetal hemoglobin; its identification and occurrence. J Chromatogr 1987 0.75
391 Factors associated with hypochromia and microcytosis among high school students in the southeastern United States. South Med J 1994 0.75
392 Hemoglobin G-San Jose (alpha 2 beta 2 7(A4)Glu replaced by Gly) in a Mexican family. Hemoglobin 1980 0.75
393 The effect of alpha-thalassemia on the level of hybrid hemoglobin variants in heterozygotes. Hemoglobin 1986 0.75
394 HB Beth Israel (beta 102 [G4] Asn replaced by Ser) observed in a Yugoslavian teenager. Hemoglobin 1978 0.75
395 Hb Strasbourg [beta 23(B5)Val-->Asp]; a high oxygen affinity variant observed in a German family. Hemoglobin 1998 0.75
396 Hb F-Brooklyn or alpha 2G gamma 2(66)(E10)Lys----Gln. Hemoglobin 1990 0.75
397 The determination of the percentages of G gamma and A gamma chains in human fetal hemoglobin by HPLC. Hemoglobin 1980 0.75
398 Two rare alpha chain variants, Hb Dunn or alpha 26(A4)Asp replaced by Asn beta 2 and Hb G-Pest or alpha 274(EF3)Asp replaced by Asn beta 2, observed in an Indian and a black newborn. Hemoglobin 1983 0.75
399 Hb Extremadura or alpha 2 beta 2133 (H11)Val----Leu, a new mildly unstable hemoglobin in a Spanish female. Hemoglobin 1989 0.75
400 Combinations of three different forms of alpha-thalassemia in a large Indian family from Durban, South Africa: hematological observations. Acta Haematol 1992 0.75
401 Hb S-Hb Lufkin disease in a black male infant. Hemoglobin 1995 0.75
402 Hb Shelby [alpha 2 beta 2(131)(H9)Gln----Lys]-beta zero-thalassemia [codon 15 (TGG----TGA)] identified by DNA sequencing. Hemoglobin 1992 0.75
403 The chemical heterogeneity of human hemoglobin F. Direct evidence for the existence of three types of gamma chain, the G gamma I, A gamma I, and A gamma T chains. Biochim Biophys Acta 1979 0.75
404 Characterization of abnormalities in the gamma-globin gene arrangements of Japanese newborns. Hemoglobin 1988 0.75
405 Homozygous beta+-thalassemia in a Dutch teenager: haematological, clinical, and genetic observations. A case report. Neth J Med 1988 0.75
406 Abnormal human haemoglobins in western Kenya. East Afr Med J 1984 0.75
407 Identification and quantitation of embryonic and three types of fetal hemoglobin produced on induction of the human pluripotent leukemia cell line K-562 with hemin. Am J Hematol 1982 0.75
408 Haplotype-specific sequence variations in the locus control region (5' hypersensitive sites 2, 3, 4) of beta S chromosomes. Hemoglobin 1993 0.75
409 Hemoglobin Fort Gordon or alpha2beta2145 Tyr replaced by Asp, a new high-oxygen-affinity hemoglobin variant. Biochim Biophys Acta 1975 0.75
410 Two different mutations in codon 68 are observed in Hb G-Philadelphia heterozygotes. Am J Hematol 1994 0.75
411 The distribution of fetal hemoglobin and the types of gamma chain in red cell fractions separated by gradient centrifugation from blood of patients with sickle cell anemia and other hemoglobinopathies. Biochem Med 1983 0.75
412 Hb A2-Manzanares or alpha 2 delta 2 121 (GH4) Glu replaced by Val, an unstable delta chain variant observed in a Spanish family. Hemoglobin 1983 0.75
413 The role of a sickle cell center in comprehensive screening and counseling for sickle cell and related disorders. South Med J 1974 0.75
414 Further modification of the microchromatographic determination of hemoglobin A2. Hemoglobin 1977 0.75
415 Black beta-thalassemia homozygotes with specific sequence variations in the 5' hypersensitive site-2 of the locus control region have high levels of fetal hemoglobin. Am J Hematol 1992 0.75
416 Hb natal or alpha 2(minus Tyr-Arg) beta 2: a high oxygen affinity alpha chain variant with a deleted carboxy-terminus resulting from a TAC----TAA (Tyr----terminating codon) mutation in codon alpha 140. Biochim Biophys Acta 1988 0.75
417 Hb Hakkari or alpha 2 beta 2 31(B13)Leu-->Arg, a severely unstable hemoglobin variant associated with numerous intra-erythroblastic inclusions and erythroid hyperplasia of the bone marrow. Hemoglobin 1995 0.75
418 Crystallography and oriented single crystal electron microscopy of hemoglobin deer II, a hemoglobin that exhibits matchstick-shaped erythrocytes. Biochim Biophys Acta 1978 0.75
419 HB Q-Thailand-HB H disease in a Chinese living in Geneva, Switzerland: characterization of the variant and identification of the two alpha-thalassemic chromosomes. Am J Hematol 1987 0.75
420 Hemoglobin Babinga or alpha 2 delta 2 136 Gly--Asp observed in the American Negro. Biochim Biophys Acta 1969 0.75
421 Association of the level of G gamma chain in the fetal hemoglobin of normal adults with specific haplotypes. Hemoglobin 1986 0.75
422 Probable inclusion-body beta-thalassemia in a Chinese family. Hemoglobin 1977 0.75
423 Some rare hemoglobin variants with altered oxygen affinities; Hb linkoping [beta 36(C2)Pro----Thr], Hb Caribbean [beta 91(F7)Leu----Arg], and Hb Sunnybrook [beta 36(C2)Pro----Arg]. Hemoglobin 1988 0.75
424 Hb A2-liangcheng [delta 117(G19)Asn->Asp(AAC->GAC)]: a new delta chain variant detected by gene analysis in a Chinese family. Hemoglobin 1993 0.75
425 Hemoglobinopathies affecting maternal-fetal oxygen gradient during pregnancy: molecular, biochemical and clinical studies. Am J Perinatol 1998 0.75
426 Hb E-Saskatoon or alpha 2 beta 2(22)(B4)Glu----Lys in a Spanish family. Hemoglobin 1987 0.75
427 Hb J-Lome or alpha 2 beta 259(E3)Lys----Asn in a Vietnamese family. Hemoglobin 1989 0.75
428 Characterization of three types of beta zero-thalassemia resulting from a partial deletion of the beta-globin gene. Hemoglobin 1989 0.75
429 Abnormal gamma-globin gene arrangements in Sardinians. Hemoglobin 1988 0.75
430 The usefulness of sequence analysis of amplified DNA for the identification of delta chain variants. Hemoglobin 1991 0.75
431 Structural studies of hemoglobin chains from Virginia white-tailed deer. Arch Biochem Biophys 1972 0.75
432 A Czechoslovakian teenager with Hb E-beta zero-thalassemia [IVS-I-1 (G----A)] complicated by the presence of an alpha-globin gene triplication. Ann Hematol 1991 0.75
433 Hemoglobin Louisville (beta 42 (CD1) phenylalanine replaced by leucine) occurring as a fresh mutation in a Canadian woman. Hemoglobin 1978 0.75
434 Sickle cell anemia identified in a multiple-transfused patient through analysis of mRNA with an RT-PCR-based technique. Acta Haematol 1995 0.75
435 Some physicochemical properties of hemoglobin-manitoba (alpha2 102Ser replaced by Arg (G9) beta2). Biochim Biophys Acta 1975 0.75
436 Hemoglobin Athens-Georgia, or alpha 2 beta 2 40(C6)Arg replaced by Lys, a hemoglobin variant with an increased oxygen affinity. Biochim Biophys Acta 1976 0.75
437 Thalassemia intermedia in two patients with Hb Lepore-beta zero-thalassemia (Frameshift codon 8, -AA). Hemoglobin 1994 0.75
438 HB Mizuho or alpha 2 beta 2 68(E12)Leu-->Pro in a young Dutch boy. Hemoglobin 1995 0.75
439 Hb F-Columbus-Ga or alpha 2 G gamma 2 94(FGl) Asp replaced by Asn. Hemoglobin 1982 0.75
440 On the structure of the hemoglobins A, A2, and F in a Negro with homozygous beta-thalassemia. Biochem Med 1974 0.75
441 The polymorphism of human fetal hemoglobin. Birth Defects Orig Artic Ser 1982 0.75
442 Binding of nuclear factors to the proximal and distal CACCC motifs of the beta-globin gene promoter: implications for the -101 (C-->T) 'silent' beta-thalassemia mutation. Acta Haematol 1994 0.75
443 An improved chromatographic procedure for quantitation of human fetal hemoglobin. Hemoglobin 1977 0.75
444 An elongated segment of DNA observed between two human alpha globin genes. Hum Genet 1986 0.75
445 Structural aspects of fetal and adult hemoglobins from nonanemic ruminants. Ann N Y Acad Sci 1974 0.75
446 A second family with the Atlanta type of HPFH. Hemoglobin 1985 0.75
447 The primary sequence of the beta chain of Hb type III of the Virginia white-tailed deer (Odocoilus Virginianus), a comparison with putative sequences of the beta chains from four additional deer hemoglobins, types II, IV, V, and VIII, and relationships between intermolecular contacts, primary sequence and sickling of deer hemoglobins. Hemoglobin 1983 0.75
448 Two delta-chain abnormal hemoglobins in one individual. Blood 1965 0.75
449 Hb F-Onoda or alpha 2G gamma 2(146)(HC3)His----Tyr, a newly discovered fetal hemoglobin variant in a Japanese newborn. Hemoglobin 1990 0.75
450 [Molecular characterization of a Spanish family with alpha-thalassemia]. Rev Clin Esp 1988 0.75
451 Heterogeneity of gamma-globin chain synthesis in Saudi newborns. Int J Hematol 1991 0.75
452 Hb Sinai-Baltimore or alpha 2 beta (2)18(A15)Val->Gly, a silent, mildly unstable beta chain variant detected by isoelectrofocusing and high performance liquid chromatography. Hemoglobin 1993 0.75
453 Hb Lulu Island (alpha 2 beta 2 107[G9]Gly-->Asp)-beta zero- thalassemia (codon 15; TGG-->TAG), a form of thalassemia intermedia. Am J Hematol 1995 0.75
454 Hb Nottingham (alpha2beta2 (FG5) 98 val leads to gly) in a Caucasian male: clinical and biosynthetic studies. Hemoglobin 1978 0.75
455 Biochemical and molecular aspects of beta-thalassemia types in northern Sardinia. Hemoglobin 1988 0.75
456 Hb Savaria or alpha(2)49(CE7)Ser----Arg beta 2 in a Yugoslavian family. Hemoglobin 1985 0.75
457 Hb Sassari or alpha (2)126(H9)Asp---His beta 2 observed in a family from Northern Sardinia. Hemoglobin 1987 0.75
458 Production of hemoglobin C in the Moufflon (Ovis musimon Pallas, 1811) and the Barbary sheep (Ammotragus lervia Pallas, 1777) during experimental anemia: amino acid composition of tryptic peptides from the beta B and bet C chains. Biochem Genet 1970 0.75
459 Hemoglobinopathies observed in the population of the Southeastern United States (SE-USA). Hemoglobin 1980 0.75
460 DNA polymorphisms in North Sardinian newborns and their linkage with abnormal gamma globin gene arrangements and with beta (0) -thalassemia. Biochem Genet 1986 0.75
461 The identification of five rare beta-chain abnormal hemoglobins by high performance liquid chromatographic procedures. Hemoglobin 1986 0.75
462 Hb Borås or alpha 2 beta 2(88)(F4)Leu----Arg in a South African female. Hemoglobin 1987 0.75
463 The Greek A gamma beta+-HPFH observed in a large black family. Am J Hematol 1987 0.75
464 Hb Camperdown or alpha 2 beta 2(104)(G6)Arg----Ser in two Italian males. Hemoglobin 1990 0.75
465 An IVS-I-117 (G-->A) acceptor splice site mutation in the alpha 1-globin gene is a nondeletional alpha-thalassaemia-2 determinant in an Indian population. Br J Haematol 1993 0.75
466 Compound heterozygosity for two alpha-globin gene defects, Hb Taybe (alpha 1; 38 or 39 minus Thr) and a poly A mutation (alpha 2; AATAAA-->AATAAG), results in a severe hemolytic anemia. Am J Hematol 1994 0.75
467 Adult hemoglobin levels in newborn babies from different countries and in babies with some significant hemoglobinopathies. Acta Haematol 1987 0.75
468 Quantities of adult, fetal and embryonic globin chains in the blood of eighteen- to twenty-week-old human fetuses. J Chromatogr 1991 0.75
469 Hb Madrid or alpha 2 beta (2)115(G17)Ala-->Pro in a black teenager. Hemoglobin 1993 0.75
470 Application of high pressure liquid chromatography and microsequencing methodology in the structural analysis of human hemoglobin variants. Sci Sin B 1983 0.75
471 Oxygen equilibrium analyses of isolated hemoglobins A2, Lepore-Washington and P-nilotic. Biochim Biophys Acta 1978 0.75
472 The frequencies of Hbs S and C in Georgia and South Carolina. Hum Genet 1991 0.75
473 Chromatographic methods for the separation of normal and abnormal hemoglobins. Hemoglobin 1980 0.75
474 Hb A2-Grovetown or alpha 2 delta (2)75(E19)Leu-->Val. Hemoglobin 1993 0.75
475 Hb Doha or alpha 2 beta 2[X-N-Met-1(NA1)Val----Glu]; a new beta-chain abnormal hemoglobin observed in a Qatari female. Biochim Biophys Acta 1985 0.75
476 Hemoglobin Alamo (alpha2beta2 19 (b1) Asn replaced by Asp). Hemoglobin 1977 0.75
477 Hb Cheverly or alpha 2 beta 2 45(CD4)Phe replaced by Ser in an elderly Italian male. Hemoglobin 1982 0.75
478 Hb F-Sacromonte or alpha 2G gamma (2)59(E3)Lys-->Gln observed in a Spanish newborn and his mother. Hemoglobin 1993 0.75
479 Observations on the calculated contents of variant and normal alpha chains in adult and fetal erythrocytes. Hemoglobin 1979 0.75
480 Gamma-chain heterogeneity of fetal hemoglobin in nonblack beta- and delta beta- thalassemia and HPFH heterozygotes and homozygotes. Am J Hematol 1982 0.75
481 Hb F-Auckland [alpha 2G gamma 2(7)(A4)Asp----Asn] observed in a Caucasian newborn from Alabama. Hemoglobin 1985 0.75
482 Hemoglobin Hamilton or alpha 2 beta 2 11(A8)Val leads to Ile: a silent beta-chain variant detected by Triton X-100 acid-urea polyacrylamide gel electrophoresis. Am J Hematol 1984 0.75
483 Hb G-Taipei or beta 22(B4)Glu----Gly in a Chinese family living in The Netherlands. Hemoglobin 1987 0.75
484 Hb F-Cobb or alpha(2)A gamma(2)37(C3)Trp----Gly. Hemoglobin 1985 0.75
485 Hb F-Jiangsu, the first gamma chain variant with a valine----methionine substitution: alpha 2A gamma 2 134(H12)Val----Met. Hemoglobin 1990 0.75
486 Hb Lepore-Baltimore (delta 68Leu-beta 84Thr) and Hb Lepore-Washington-Boston (delta 87Gln-beta IVS-II-8) in central Portugal and Spanish Alta Extremadura. Hum Genet 1997 0.75
487 Microchromatographic quantitation of fetal hemoglobin in patients with sickle cell disease. Hemoglobin 1979 0.75
488 Hemoglobin Kariya or alpha 240(C5)Lys----Glu beta 2 in a Caucasian family from South Carolina. Hemoglobin 1984 0.75
489 Hb F-Oakland or alpha 2G gamma I2(26)(B8)Glu----Lys. Hemoglobin 1987 0.75
490 Beta-thalassemia due to frameshifts at codons 5, 6, 8, and 8/9; hematological observations in heterozygotes. Hemoglobin 1990 0.75
491 Usefulness of HPLC methodology for the characterization of combinations of the common beta chain variants Hbs S, C, and O-Arab, and the alpha chain variant Hb G-Philadelphia. Hemoglobin 1993 0.75
492 HB G-Copenhagen or alpha 2 beta 2(47) (CD6) Asp----Asn observed in a black newborn. Hemoglobin 1985 0.75
493 Hb G-Szuhu or alpha 2 beta 2(80)(EF4)Asn----Lys, in combination with beta zero-thalassemia in a Spanish family. Hemoglobin 1985 0.75
494 Hb F-Xin-Su or A gamma I73(E17)Asp----His: a new slow-moving fetal hemoglobin variant. Hemoglobin 1987 0.75
495 Gene duplication of the alpha chain of goat hemoglobin: evidence from a homozygous mutant. Biochim Biophys Acta 1968 0.75
496 Hb F-Veleta or alpha 2 G gamma(2)40(C6)Arg-->Gly. Hemoglobin 1995 0.75
497 Transient chloramphenicol acetyltransferase expression of the G gamma globin gene 5'-flanking regions containing substitutions of C----T at position -158, G----A at position -161, and T----A at position -175 in K562 cells. Biochim Biophys Acta 1989 0.75
498 The effect of pH on the uptake of methylene blue by human red cells. Clin Chim Acta 1970 0.75
499 Beta-thalassemia intermedia in an Indian female with the Hb Hofu [beta 126(H4)Val-->Glu]-beta zero-thalassemia [codons 8/9 (+G)] combination. Hemoglobin 1995 0.75
500 A new gene deletion involving the alpha 2-, alpha 1-, and theta 1-globin genes in a black family with Hb H disease. Am J Hematol 1992 0.75
501 Hb Capa or alpha (2)94(G1)Asp-->Gly beta 2, a mildly unstable variant with an A-->G (GAC-->GGC) mutation in codon 94 of the alpha 1-globin gene. Hemoglobin 1994 0.75
502 Peripheral haemolysis, lipid peroxidation, iron status, and vitamin E in haemoglobin H syndromes in West Malaysia. Singapore Med J 1993 0.75
503 Hb Davenport or alpha 2(78)(EF7)Asn----His beta 2. Hemoglobin 1990 0.75
504 The alpha / beta and alpha 2 / alpha 1-globin mRNA ratios in different forms of alpha-thalassemia. Biochim Biophys Acta 1996 0.75
505 Beta zero-thalassemia in association with a gamma-globin gene quadruplication. Blood 1986 0.75
506 In vitro synthesis of hemoglobin and hemoglobin chains in the BFUe-derived colonies form person with alpha- or beta-thalassemia. Am J Hematol 1981 0.75
507 Long survival in sickle cell anemia. Trop Geogr Med 1975 0.75
508 Hemoglobin Riyadh-beta 0-thalassemia in an Indian family. Hemoglobin 1979 0.75
509 The thalassemia syndromes in association with hemoglobinopathies in southern China. Hemoglobin 1988 0.75
510 Hemoglobin Chapel Hill or alpha2 74 Asp replaced by Gly beta2. FEBS Lett 1976 0.75
511 [Molecular-genetic characteristics of alpha, beta and delta beta-thalassemias in 139 heterozygotes in 56 unrelated Czech and Slovak families (Priority description of 3 beta-thalassemia mutations, an extensive alpha-thalassemia 2 (18+ kb) deletion and a Swiss-type nondeletion hereditary persistence of hemoglobin F)]. Vnitr Lek 1993 0.75
512 Heterozygosity and homozygosity for the high oxygen affinity hemoglobin Tarrant or alpha 126 (H9) Asp replaced by Asn in two Mexican families. Hemoglobin 1981 0.75
513 Hb F-Kennestone or alpha 2G gamma 2 (EF1)77 His leads to Arg observed in a Caucasian baby. Hemoglobin 1983 0.75
514 The T-->C mutation at position +96 of the untranslated region 3' to the terminating codon of the beta-globin gene is a rare polymorphism that does not cause a beta-thalassemia as previously ascribed. Hum Genet 1994 0.75
515 Hb Fannin-Lubbock in five Spanish families is characterized by two mutations: beta 111 GTC-->CTC (Val-->Leu) and beta 119 GGC-->GAC (Gly-->Asp). Hemoglobin 1994 0.75
516 Saudi Arabian sickle cell anemia. A molecular approach. Ann N Y Acad Sci 1989 0.75
517 Hemoglobins A 2 -Sphakiá and A 2 -NYU in Canada. Can J Biochem 1972 0.75
518 Structure of human hemoglobin C: a disease with intraerythrocytic crystals. Biochim Biophys Acta 1979 0.75
519 [Hemoglobin F Catalonia. A new variant of fetal hemoglobin]. Sangre (Barc) 1991 0.75
520 Hb Nottingham or alpha 2 beta 2(98)(FG5)Val----Gly observed as a de novo mutation in a Canadian child. Hemoglobin 1992 0.75
521 Hb F-Bonaire-Ga or alpha 2 A gamma 2 39(C5) Gln replaced by Arg, characterized by high pressure liquid chromatographic and microsequencing procedures. Hemoglobin 1982 0.75
522 Hemoglobin Daneshgah-Tehran or alpha 2(72) (EF1) His----Arg beta 2 in an Argentinean family. Hemoglobin 1985 0.75
523 The percentages of Hb F and of G gamma and A gamma chains in the Hb F synthesized by reticulocytes and BFUe-derived colonies of patients with sickle cell anemia. Hemoglobin 1982 0.75
524 The structure of sheep hemoglobins. 3. Structural studies on the alpha chain of hemoglobin A. J Biol Chem 1968 0.75
525 Hb F-Charlotte, an A gamma variant with a threonine residue in position gamma 75 and a glycine residue in position gamma 136. Hemoglobin 1990 0.75
526 Hb Sabine or alpha 2 beta 2 91 (F7) Leu----Pro in a Yugoslavian boy. Hemoglobin 1983 0.75
527 The structure of goat hemoglobins. V. A fourth beta chain variant (beta-D-Malta; 69 Asp is replaced by Gly) with decreased oxygen affinity and occurring at a high frequency in Malta. Hemoglobin 1979 0.75
528 Hb Cordele alpha(2)47 (CE5)Asp----Ala beta 2. A mildly unstable variant observed in black twins. Hemoglobin 1984 0.75
529 Hb Ethiopia or alpha 2(140)(HC2)Tyr----His beta 2. Hemoglobin 1992 0.75
530 Haemoglobin M Saskatoon and haemoglobin M Hyde Park in two Yugoslavian families. Scand J Haematol 1974 0.75
531 Hb A2-Wrens or alpha 2 delta 2 98(FG5) Val----Met, an unstable delta chain variant identified by sequence analysis of amplified DNA. Biochim Biophys Acta 1989 0.75
532 Hb Suresnes or alpha2 141(HC3) ArgyieldHis beta2 in a black family. Hemoglobin 1978 0.75
533 An unusual phenotypic expression of Hb-Leiden. Biochem Genet 1982 0.75
534 Hb F-Saskatoon or alpha 2G gamma (2)21(B3)Glu-->Lys observed in a North American Indian newborn. Hemoglobin 1993 0.75
535 Low quantities of Hb Boyle Heights or alpha 2(6)(A4)Asp----O beta 2 observed in three members of a Caucasian family. Hemoglobin 1990 0.75
536 Hb Gainesville-GA or alpha 2 beta 2(46)(CD5)Gly----Arg; second report. Hemoglobin 1989 0.75
537 Hb Mizuho or alpha 2 beta (2)68(E12)Leu----Pro in a Caucasian boy with high levels of Hb F; identification by sequencing of amplified DNA. Hemoglobin 1991 0.75
538 Hb Olomouc or alpha 2 beta 2(86)(F2)Ala----Asp, a new high oxygen affinity variant. Hemoglobin 1987 0.75
539 Hemoglobin F levels in patients with chronic renal failure. Hemoglobin 1977 0.75
540 Unstable Hb Newcastle [beta92(F8)His-->Pro], first case discovered in a Russian patient. Hemoglobin 1999 0.75
541 Identification of the alpha chain abnormal hemoglobin Jackson (alpha 127 Lys leads to Asn) after isolation of the core peptide by high-performance liquid chromatography. J Chromatogr 1983 0.75
542 A comparison of two procedures useful for the isolation of Hb F from adult red blood cells and for the quantitation of the types of gamma chain by high-performance liquid chromatography. J Chromatogr 1984 0.75
543 Molecular heterogeneity of beta-thalassemia intermedia in Turkey. Acta Haematol 1989 0.75
544 Hb F-Catalonia or alpha 2G gamma(2)15(A12)Trp----Arg. Hemoglobin 1990 0.75
545 Letter: Hereditary persistence of foetal haemoglobin. Nature 1975 0.75
546 Thalassemia intermedia caused by heterozygosity for both beta-thalassemia and hemoglobin Saki [beta 14 (A11) Leu replaced by Pro]. Am J Hematol 1976 0.75
547 Hb F-Meinohama or alpha 2 gamma 2 (5 Glu replaced by Gly; 75 Ile; 136 Gly). Hemoglobin 1981 0.75
548 The beta zero-thalassemia in an American black family is due to a single nucleotide substitution in the acceptor splice junction of the second intervening sequence. Am J Hematol 1986 0.75
549 Hb Anamosa or alpha 2(111)(G18)Ala-->Val beta 2 (alpha 2 mutation) and Hb Mulhacen or alpha 2(123)(H6)Ala-->Ser beta 2 (alpha 1 mutation) are two silent, stable variants detected by sequencing of amplified DNA. Hemoglobin 1995 0.75
550 Hemoglobin Hofu or alpha 2 beta 2 [126 (H4) Va1 leads to Glu] found in combination with hemoglobin S. Hemoglobin 1978 0.75
551 Haemoglobin Presbyterian [beta 108 (G 10) Asn----Lys] in a Spanish family. Acta Haematol 1986 0.75
552 Homozygosity for hemoglobin O-Arab (alpha 2 beta 2 121 Glu----Lys). Hb O-Arab disease. Turk J Pediatr 1986 0.75
553 A second observation of Hb Abruzzo [alpha 2 beta 2(143)(H21)His----Arg] in an Italian family. Hemoglobin 1990 0.75
554 Hemoglobin S-Ga Georgia disease: a case report. Acta Haematol 1974 0.75
555 Genetic aspects of gamma chain synthesis. Hamatol Bluttransfus 1972 0.75
556 Hb Savaria or alpha2 (49)(CE7)Ser----Arg beta2 in an indigenous female from Kenya. Hemoglobin 1985 0.75
557 Hb D-Granada or alpha 2 beta 2 22(B4)Glu----Val. Hemoglobin 1987 0.75
558 Hb S(C)-beta+-thalassaemia: different mutations are associated with different levels of normal Hb A. Br J Haematol 1988 0.75
559 The frequency of the A gamma T gene in the presence and absence of the beta S or beta C gene in the Black population of the Southeastern USA. Hemoglobin 1981 0.75
560 Heterogeneity of fetal hemoglobin among Israel families with beta-thalassemia. Isr J Med Sci 1974 0.75
561 The unstable Hb Hammersmith or alpha 2 beta 2(42)(CD1)Phe----Ser observed in an Indian child; identification by HPLC and by sequence analysis of amplified DNA. Hemoglobin 1992 0.75
562 A second, elongated, alpha 2-globin mRNA is present in reticulocytes from normal persons and subjects with terminating codon or poly A mutations. Biochem Biophys Res Commun 1995 0.75
563 Hb Fukuyama or alpha 2 beta(2)77(EF1)His----Tyr observed in an Indonesian female. Hemoglobin 1991 0.75
564 Hb A2-Zagreb or alpha 2 delta 2(125)(H3)Gln replaced by Glu, a new delta chain variant in association with delta beta-thalassemia. Hemoglobin 1983 0.75
565 The first homozygote for the hereditary persistence of fetal hemoglobin observed in the southeastern United States. Hemoglobin 1981 0.75
566 [Haplotype in 3 patients homozygous for beta-thalassemia]. Sangre (Barc) 1987 0.75
567 Heterogeneity of the hemoglobin of the Ohrid trout (Salmo L. typicus). Biochem Genet 1992 0.75
568 Hb F-Marietta or G gamma I 80[EF4] Asp replaced by Asn, observed in a Caucasian baby. Hemoglobin 1982 0.75
569 An Indonesian family with the Southeast Asian type of alpha-thalassemia-1 and a gamma-globin gene triplication. Acta Haematol 1987 0.75
570 Postnatal changes in the quantities of globin chains and hemoglobin types in two babies with Hb H disease. Am J Hematol 1993 0.75
571 Two hemoglobin phenotypes in the American bison (Bison bison): a possible genetic explanation based on structural studies. Biochem Genet 1973 0.75
572 Percentages of abnormal hemoglobins in adults with a heterozygosity for an alpha-chain and/or a beta-chain variant. Am J Hematol 1983 0.75
573 Hb-Genova ( 2 2 28(B10)Leu leads to Pro ); methods for detection and analysis of unstable hemoglobins. Clin Chim Acta 1973 0.75
574 Hb Zengcheng or alpha 2 beta(2)114(G16)Leu----Met. Hemoglobin 1990 0.75
575 Hb Köln or alpha 2 beta 2(98)(FG5)Val----Met in a Czechoslovakian family. Hemoglobin 1991 0.75
576 Hb Hradec Kralove (Hb HK) or alpha 2 beta 2 115(G17)Ala-->Asp, a severely unstable hemoglobin variant resulting in a dominant beta-thalassemia trait in a Czech family. Hemoglobin 1993 0.75
577 beta S-haplotypes and alpha-thalassemia along the coastal belt of Kenya. East Afr Med J 1989 0.75
578 The gamma chain heterogeneity of fetal hemoglobin in black beta-thalassemia and HPFH heterozygotes. Blood 1981 0.75
579 Three sickle cell anemia patients each with a different alpha chain variant. Diagnostic complications. Hemoglobin 1993 0.75
580 A new delta chain variant, haemoglobin-A2-Melbourne or alpha2 delta2 43Glu-Lys(CD2). Biochim Biophys Acta 1974 0.75
581 Hb Chapel Hill or alpha 274(EF3)Asp----Gly beta 2 observed in a Chinese family in association with beta-thalassemia. Hemoglobin 1986 0.75
582 [Preferential synthesis of fetal hemoglobin in in vitro cultures of erythroid precursors from peripheral blood of healthy persons and those with hemoglobinopathies]. Bilt Hematol Transfuz 1979 0.75
583 Hb J-Pontoise or alpha 2(63)(E12)Ala----Asp beta 2 in four members of a Spanish family. Hemoglobin 1987 0.75
584 Fetal hemoglobin heterogeneity in Chinese newborns of the Uygur and Han nationalities; comparisons of babies from Xinjiang and Beijing. Hemoglobin 1987 0.75
585 Hb J-Antakya or alpha 2 beta (2)65(E9)Lys----Met in a Turkish family and Hb complutense or alpha 2 beta (2)127(H5)Gln----Glu in a Spanish family; correction of a previously published identification. Biochim Biophys Acta 1986 0.75
586 Two rare unstable beta chain variants, Hb Mozhaisk or alpha 2 beta 292(F8)His----Arg and Hb Djelfa or alpha 2 beta 298(Fg5)Val----Ala, each being observed for the second time. Hemoglobin 1989 0.75
587 A newly discovered frameshift at codons 120-121 (+A) of the beta gene is not associated with a dominant form of beta-thalassemia. Blood 1996 0.75
588 Variability in the interaction of beta-thalassemia with the alpha-chain variants Hb G-Philadelphia and Hb Rampa. J Lab Clin Med 1978 0.75
589 Zeta and theta 1-globin gene deletions located on the same chromosome. Br J Haematol 1989 0.75
590 Hb Lepore-Baltimore in a north Sardinian family. Hemoglobin 1990 0.75
591 A second observation of Hb F-Lodz or alpha 2G gamma (2)44(CD3)Ser----Arg. Hemoglobin 1991 0.75
592 Separation of the A gamma and G gamma cyanogen bromide peptides of human fetal hemoglobin by high-pressure liquid chromatography. Anal Biochem 1979 0.75
593 Hb Regina or alpha 2 beta 2 96(FG3)Leu----Val: a high oxygen affinity variant discovered by cation-exchange HPLC. Am J Hematol 1985 0.75
594 Viscosity and gelation studies in deer hunting hemoglobins. Proc Soc Exp Biol Med 1975 0.75
595 A second family with Hb Minneapolis-Laos or alpha 2 beta (2)118(GH1)Phe----Tyr. Hemoglobin 1987 0.75
596 Is the trimodality of Hb Leslie (alpha 2 beta 2 131 Gln---O) in heterozygotes the result of a variable number of active alpha-chain genes? Evidence for posttranslational control of hemoglobin synthesis. Am J Hematol 1978 0.75
597 Hb-Volga or alpha 2 beta 2 27(B9)Ala replaced by Asp. An unstable hemoglobin variant in three generations of a Dutch family. Biochim Biophys Acta 1976 0.75
598 Hb Rainier or alpha 2 beta 2 (145 (HC2) Tyr replaced by Cys) observed in members of a Canadian family of Greek origin. Hemoglobin 1979 0.75
599 MRNA analysis in reticulocytes of subjects with Hb D, Hb Porto Alegre, Hb E, and different types of unstable hemoglobin variants. Am J Hematol 1996 0.75
600 Historical note: the beta-thalassemia allele in the noble Russian family Lermontov is identified as the ATG-->ACG change in the initiation codon. Hemoglobin 1998 0.75
601 Haemoglobin alpha chain duplication in Barbary sheep, Ammotragus lervia, Pallas, 1777. Nature 1970 0.75
602 Detection of the alpha-thalassemia-2 (3.7 kb) deletion in DNA extracted from 20-year-old blood smears. Hemoglobin 1997 0.75
603 A new gamma chain variant: Hb F-Pordenone [gamma 6(A3) Glu replaced by Gln: 75ILE: 136ALA]. Hemoglobin 1982 0.75
604 A mutation associated with elevated G gamma chain in sickle cell anemia and hereditary persistence of fetal hemoglobin. Prog Clin Biol Res 1985 0.75
605 Identification of hemoglobin G-Philadelphia (alpha 68 Asn replaced by Lys) and hemoglobin Matsue-Oki (alpha 75 Asp replaced by Asn) in a black infant. Biochim Biophys Acta 1982 0.75
606 3. Hemoglobin heterogeneity and structural genes. CRC Crit Rev Clin Lab Sci 1970 0.75
607 Hb F-Baskent or alpha 2A gamma 128(H6)Ala----Thr. Hemoglobin 1988 0.75
608 The combination of HB S and HB E in a black female. Hemoglobin 1977 0.75
609 Hb F-Calluna or alpha 2 gamma 2(12 Thr replaced by Arg; 75Ile; 136Ala) in a Caucasian baby. Hemoglobin 1983 0.75
610 Hb Ramona or alpha (2)24(B5)Tyr-->Cys beta 2. Hemoglobin 1994 0.75
611 Further evidence for non-linkage of the Hb and Hb structural loci in man. Clin Chim Acta 1972 0.75
612 The quantities of various minor hemoglobin components in old and young human red blood cells. Clin Chim Acta 1967 0.75
613 Hb Bushwick [beta 74(E18)Gly----Val] heterozygotes in a Yugoslavian family have 35 to 40% of the unstable variant. Hemoglobin 1987 0.75
614 Hb Summer Hill or alpha 2 beta 2(52)(D3)Asp replaced by His in a Turkish family from Cyprus. Hemoglobin 1983 0.75
615 Hb Chandigarh or alpha 2 beta 2(94)(FG1)Asp----Gly observed in an Indian family. Hemoglobin 1989 0.75
616 A mild thalassemia major resulting from a compound heterozygosity for the IVS-II-1 (G----A) mutation and the rare T----C mutation at the polyadenylation site. Hemoglobin 1991 0.75
617 Globin mRNA in beta-thalassemia heterozygotes with different beta-thalassemia alleles and in heterozygotes for hereditary persistence of fetal hemoglobin. Acta Haematol 1996 0.75
618 Hemoglobin types in Barbary sheep (Ammotragus lervia Pallas, 1777); absence of a betaC production in a homozygous beta C(na) animal during severe anemia. Proc Soc Exp Biol Med 1972 0.75
619 Hb Albany-GA or alpha 2(11)(A9)Lys leads to Asn beta 2. Hemoglobin 1983 0.75
620 Hb F-Clarke or alpha 2G gamma 2(65)(E9)Lys----Asn. Hemoglobin 1987 0.75
621 Hb Beograd (alpha2 beta2 121 (GH4) Glu replaced by Val) observed in a new Yugoslavian family. Hemoglobin 1978 0.75
622 Hb Westmead [alpha 122(H5)His----Gln], Hb E [beta 26(B8)Glu----Lys], and alpha-thalassemia-2 (3.7 Kb deletion) in a Laotian family. Hemoglobin 1991 0.75
623 Hemoglobin Hacettepe or alpha 2 beta 2 127 (H5) Gln replaced by Glu. Biochim Biophys Acta 1976 0.75
624 Synthesis of hemoglobin chains in adult and newborn goats: possible influence of the beta c synthesis on the production of alpha chains. Hemoglobin 1982 0.75
625 Compound heterozygosity for a mild beta (+) and a rare beta(0)-thalassemia allele. Acta Haematol 1990 0.75
626 Alpha-thalassemia and the production of different alpha chain variants in heterozygotes. Biochem Genet 1981 0.75
627 Relative levels of alpha-, beta-, and gamma-mRNA from patients with severe and intermediate beta-thalassemia major. Acta Haematol 1997 0.75
628 Studies on the heterogeneity of hemoglobin. XVI. Separation of variants with a GlU-Lys substitution by chromatography on CM-cellulose. J Chromatogr 1974 0.75
629 Chemical heterogeneity of foetal haemoglobin in the Lepore haemoglobinopathy. Br J Haematol 1974 0.75
630 Hb Beograd-beta zero thalassemia in a Turkish family from Yugoslavia. Hemoglobin 1984 0.75
631 [Homozygote beta-thalassemia in 2 Dutch families]. Ned Tijdschr Geneeskd 1989 0.75
632 Quantities of alpha Q chain variants in heterozygotes with and without a concomitant beta-thalassemia trait. Am J Hematol 1994 0.75
633 Oxygen equilibria and biochemical changes of whole blood stored in different preservation media. Transfusion 1969 0.75
634 Identical nucleotide sequences of the 3'A gamma globin gene enhancer elements from four different chromosomes. Blood 1989 0.75
635 Hb Guangzhou-Hangzhou or alpha 2(64)(E13)Asp----Gly beta 2 observed in members of a Chinese family living in Xinjiang. Hemoglobin 1990 0.75
636 The structure of goat hemoglobins. 3. Hemoglobin D, a beta chain variant with one apparet amino acid substitution (21 Asp--His). Arch Biochem Biophys 1968 0.75
637 Hb P-Nilotic or alpha 2(beta delta)2 in a Turkish family. Hemoglobin 1987 0.75
638 Hb F-Forest Park, a new A gamma variant with two amino acid substitutions, 75(E19)Ile----Thr and 73(E17)Asp----Asn, which can be identified in adults by gene-mapping analysis. Biochim Biophys Acta 1985 0.75
639 Further studies on the quantitation of the hemoglobins A, S, C, and F in newborn babies with different hemoglobinopathies using high pressure liquid chromatography. Hemoglobin 1982 0.75
640 Detection of a new hybrid alpha 2 globin gene among American blacks. Hum Genet 1988 0.75
641 Carboxymethyl-cellulose microchromatography for the quantitation of hemoglobin Bart's (gamma 4) and its use in the detection of the alpha-thalassemia conditions. J Chromatogr 1980 0.75
642 Restriction endonuclease gene mapping studies of an Indian (A gamma delta beta)zero-thalassaemia, previously identified as G gamma-HPFH. Br J Haematol 1984 0.75
643 Hb Volga or alpha 2 beta 2 27(B9)Ala----Asp in an Italian family. Hemoglobin 1985 0.75
644 Hb Cleveland or alpha 2 beta 2(93)(F9)Cys----Arg;121(GH4)Glu----Gln. Hemoglobin 1991 0.75
645 [Structural variants in hemoglobin occurring in the Czech Republic]. Vnitr Lek 1995 0.75
646 Effect of severe hemorrhage on the hemoglobins of a Virginian white-tailed deer (Odocoileus virginianus). Proc Soc Exp Biol Med 1968 0.75
647 Distribution of beta-thalassemia mutations in three Asian Indian populations with distant geographical locations. Hemoglobin 1994 0.75
648 [Hemoglobin Complutense (beta 127 (H5) Gln replaced by Glu) in a Spanish family]. Sangre (Barc) 1987 0.75
649 Hb Porto Alegre or alpha 2 beta 29(A6)Ser->Cys in unrelated families of the Canary Islands. Hemoglobin 1993 0.75
650 The in vivo expression of the globin genes of the beta cistron in gamma-, delta-, and delta beta-thalassemia heterozygotes. Experientia 1994 0.75
651 Co-inheritance of Hb D-Punjab (codon 121; GAA-->CAA) and beta (0) -thalassemia (IVS-II-1;G-->A). J Pediatr Hematol Oncol 1996 0.75
652 Construction of three plasmids, each containing two or three different human globin gene fragments. Hemoglobin 1988 0.75
653 Hb Brockton [alpha 2 beta 2(138)(H16)Ala-->Pro] observed in a Spanish girl. Hemoglobin 1992 0.75
654 Quantitation of hemoglobins Bart's, H, Portland-I, Portland-II and constant spring by anion-exchange high-performance liquid chromatography. J Chromatogr 1989 0.75
655 Hb Etobicoke, alpha 85(F5) Ser leads to Arg found in a newborn of French-Indian-English descent. Hemoglobin 1983 0.75
656 Posttranslational modification of beta 141 Leu associated with the beta 75(E19)Leu-->Pro mutation in Hb Atlanta. Hemoglobin 1993 0.75
657 Geographic distribution of hemoglobin variants in the white-tailed deer. J Mammal 1973 0.75
658 Hb F-Albaicin or G gamma 8(A5)Lys----Glu or Gln. Hemoglobin 1986 0.75
659 Hb F-Beech Island or alpha 2A gamma 2(53)(D4)Ala----Asp. Hemoglobin 1985 0.75
660 Detection of the embryonic zeta chain in blood from newborn babies by reversed-phase high-performance liquid chromatography. J Chromatogr 1987 0.75
661 Hb F-Pendergrass, an A gamma I variant with a Pro----Arg substitution at position gamma 36(C2). Hemoglobin 1985 0.75