PubRank

P S Perlman

Author PubWeight™ 132.58‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Secondary structure of the Tetrahymena ribosomal RNA intervening sequence: structural homology with fungal mitochondrial intervening sequences. Proc Natl Acad Sci U S A 1983 4.78
2 A self-splicing RNA excises an intron lariat. Cell 1986 3.74
3 A latent intron-encoded maturase is also an endonuclease needed for intron mobility. Cell 1989 2.90
4 Group II intron domain 5 facilitates a trans-splicing reaction. Mol Cell Biol 1988 2.89
5 Group II intron mobility occurs by target DNA-primed reverse transcription. Cell 1995 2.86
6 Efficient integration of an intron RNA into double-stranded DNA by reverse splicing. Nature 1996 2.67
7 Group II intron self-splicing. Alternative reaction conditions yield novel products. J Biol Chem 1988 2.52
8 Involvement of aminoacyl-tRNA synthetases and other proteins in group I and group II intron splicing. Trends Biochem Sci 1990 2.49
9 A group II intron RNA is a catalytic component of a DNA endonuclease involved in intron mobility. Cell 1995 2.37
10 Derepression of mitochondria and their enzymes in yeast: regulatory aspects. Arch Biochem Biophys 1974 2.37
11 Mobile introns: definition of terms and recommended nomenclature. Gene 1989 2.26
12 Evolutionary relationships among group II intron-encoded proteins and identification of a conserved domain that may be related to maturase function. Nucleic Acids Res 1993 2.24
13 Mechanisms of intron mobility. J Biol Chem 1995 2.21
14 The sorting of mitochondrial DNA and mitochondrial proteins in zygotes: preferential transmission of mitochondrial DNA to the medial bud. J Cell Biol 1998 1.96
15 In organello formaldehyde crosslinking of proteins to mtDNA: identification of bifunctional proteins. Proc Natl Acad Sci U S A 2000 1.94
16 Mobility of yeast mitochondrial group II introns: engineering a new site specificity and retrohoming via full reverse splicing. Cell 1997 1.91
17 Functions of the high mobility group protein, Abf2p, in mitochondrial DNA segregation, recombination and copy number in Saccharomyces cerevisiae. Genetics 1998 1.85
18 Group II introns deleted for multiple substructures retain self-splicing activity. Mol Cell Biol 1992 1.77
19 Functional domains in introns: trans-acting and cis-acting regions of intron 4 of the cob gene. Cell 1982 1.75
20 Group II intron endonucleases use both RNA and protein subunits for recognition of specific sequences in double-stranded DNA. EMBO J 1997 1.75
21 Reverse transcriptase activity associated with maturase-encoding group II introns in yeast mitochondria. Cell 1993 1.71
22 Group II intron splicing in vivo by first-step hydrolysis. Nature 1998 1.68
23 Analysis of mitochondrial DNA nucleoids in wild-type and a mutant strain of Saccharomyces cerevisiae that lacks the mitochondrial HMG box protein Abf2p. Nucleic Acids Res 1996 1.61
24 Mobile group II introns of yeast mitochondrial DNA are novel site-specific retroelements. Mol Cell Biol 1995 1.59
25 Intracellular localization of enzymes in yeast. Arch Biochem Biophys 1970 1.57
26 The stereochemical course of group II intron self-splicing. Science 1994 1.53
27 The high mobility group protein Abf2p influences the level of yeast mitochondrial DNA recombination intermediates in vivo. Proc Natl Acad Sci U S A 1998 1.52
28 The effect of zygotic bud position on the transmission of mitochondrial genes in Saccharomyces cerevisiae. Mol Gen Genet 1978 1.47
29 Functional expression of a yeast mitochondrial intron-encoded protein requires RNA processing at a conserved dodecamer sequence at the 3' end of the gene. Mol Cell Biol 1989 1.47
30 Catalytically critical nucleotide in domain 5 of a group II intron. Proc Natl Acad Sci U S A 1995 1.41
31 An enzyme in yeast mitochondria that catalyzes a step in branched-chain amino acid biosynthesis also functions in mitochondrial DNA stability. EMBO J 1995 1.37
32 Studies of point mutants define three essential paired nucleotides in the domain 5 substructure of a group II intron. Mol Cell Biol 1995 1.37
33 The numbers of individual mitochondrial DNA molecules and mitochondrial DNA nucleoids in yeast are co-regulated by the general amino acid control pathway. EMBO J 2000 1.35
34 Multiple homing pathways used by yeast mitochondrial group II introns. Mol Cell Biol 2000 1.30
35 Purification of a site-specific endonuclease, I-Sce II, encoded by intron 4 alpha of the mitochondrial coxI gene of Saccharomyces cerevisiae. J Biol Chem 1990 1.29
36 Molecular consequences of ethidium bromide mutagenesis. Nat New Biol 1971 1.27
37 Intron 5 alpha of the COXI gene of yeast mitochondrial DNA is a mobile group I intron. Nucleic Acids Res 1992 1.25
38 Group II intron mobility in yeast mitochondria: target DNA-primed reverse transcription activity of aI1 and reverse splicing into DNA transposition sites in vitro. J Mol Biol 1998 1.23
39 More than one way to splice an RNA: branching without a bulge and splicing without branching in group II introns. RNA 1998 1.20
40 Molecular genetics of populations of intracellular bacteria: the spotted fever group rickettsiae. Ann N Y Acad Sci 1990 1.19
41 Maturase and endonuclease functions depend on separate conserved domains of the bifunctional protein encoded by the group I intron aI4 alpha of yeast mitochondrial DNA. EMBO J 1995 1.19
42 [Mitochondriogenesis analyzed by blocks on mitochondrial translation and transcription]. Biochemistry 1971 1.19
43 Stereochemical selectivity of group II intron splicing, reverse splicing, and hydrolysis reactions. Mol Cell Biol 1995 1.19
44 Asymmetric gene conversion at inserted segments on yeast mitochondrial DNA. Nature 1978 1.15
45 Retrotransposition of a yeast group II intron occurs by reverse splicing directly into ectopic DNA sites. Proc Natl Acad Sci U S A 2001 1.15
46 Pentamidine inhibits mitochondrial intron splicing and translation in Saccharomyces cerevisiae. RNA 2000 1.15
47 Complex recognition site for the group I intron-encoded endonuclease I-SceII. Mol Cell Biol 1992 1.14
48 Mutation of the conserved first nucleotide of a group II intron from yeast mitochondrial DNA reduces the rate but allows accurate splicing. J Biol Chem 1993 1.13
49 Kinetic and segregational analysis of mitochondrial DNA recombination in yeast. Plasmid 1987 1.13
50 A UV-induced, Mg(2+)-dependent crosslink traps an active form of domain 3 of a self-splicing group II intron. RNA 1995 1.13
51 Group II intron reverse transcriptase in yeast mitochondria. Stabilization and regulation of reverse transcriptase activity by the intron RNA. J Mol Biol 1999 1.12
52 Domain 5 interacts with domain 6 and influences the second transesterification reaction of group II intron self-splicing. Nucleic Acids Res 1993 1.11
53 Group II intron self-splicing: development of alternative reaction conditions and identification of a predicted intermediate. Cold Spring Harb Symp Quant Biol 1987 1.11
54 Mutations of the two-nucleotide bulge of D5 of a group II intron block splicing in vitro and in vivo: phenotypes and suppressor mutations. RNA 1996 1.10
55 Regulatory interactions between mitochondrial genes: interactions between two mosaic genes. Proc Natl Acad Sci U S A 1981 1.10
56 A maturase-encoding group IIA intron of yeast mitochondria self-splices in vitro. Nucleic Acids Res 1992 1.09
57 The nuclear SUV3-1 mutation affects a variety of post-transcriptional processes in yeast mitochondria. Nucleic Acids Res 1990 1.09
58 Functional domains in introns. RNA processing intermediates in cis- and trans-acting mutants in the penultimate intron of the mitochondrial gene for cytochrome b. J Biol Chem 1983 1.08
59 Transformation of Saccharomyces cerevisiae mitochondria using the biolistic gun. Methods Enzymol 1996 1.08
60 The two steps of group II intron self-splicing are mechanistically distinguishable. RNA 1998 1.08
61 Replication and preferential inheritance of hypersuppressive petite mitochondrial DNA. EMBO J 2001 1.07
62 In vivo double-strand breaks occur at recombinogenic G + C-rich sequences in the yeast mitochondrial genome. Proc Natl Acad Sci U S A 1988 1.06
63 Expandable var1 gene of yeast mitochondrial DNA: in-frame insertions can explain the strain-specific protein size polymorphisms. Proc Natl Acad Sci U S A 1984 1.06
64 Domain 5 binds near a highly conserved dinucleotide in the joiner linking domains 2 and 3 of a group II intron. RNA 1998 1.06
65 Control of branch-site choice by a group II intron. EMBO J 2001 1.05
66 The unusual varl gene of yeast mitochondrial DNA. Science 1985 1.03
67 Novel hybrid maturases in unstable pseudorevertants of maturaseless mutants of yeast mitochondrial DNA. Nucleic Acids Res 1990 1.01
68 Targeting of green fluorescent protein to mitochondria. Methods Cell Biol 2001 1.00
69 Uniparental inheritance of mitochondrial genes in yeast: dependence on input bias of mitochondrial DNA and preliminary investigations of the mechanism. Genetics 1978 1.00
70 A novel class of Saccharomyces cerevisiae mutants specifically UV-sensitive to "petite" induction. Mol Gen Genet 1976 0.98
71 Photocrosslinking of 4-thio uracil-containing RNAs supports a side-by-side arrangement of domains 5 and 6 of a group II intron. RNA 1999 0.97
72 Genetic analysis of RNA splicing in yeast mitochondria. Methods Enzymol 1990 0.96
73 Mitochondrial genetics in Bakers' yeast: a molecular mechanism for recombinational polarity and suppressiveness. Proc Natl Acad Sci U S A 1974 0.94
74 Regulatory interactions between mitochondrial genes. I. Genetic and biochemical characterization of some mutant types affecting apocytochrome b and cytochrome oxidase. J Biol Chem 1979 0.94
75 Length changes in the joining segment between domains 5 and 6 of a group II intron inhibit self-splicing and alter 3' splice site selection. Mol Cell Biol 1996 0.94
76 "Killer" character does not influence the transmission of mitochondrial genes in Saccharomyces cerevisiae. J Bacteriol 1975 0.90
77 Genetic analysis of petite mutants of Saccharomyces cerevisiae: transmissional types. Genetics 1976 0.90
78 Evidence for translated intervening sequences in the mitochondrial genome of Saccharomyces cerevisiae. J Biol Chem 1982 0.89
79 Mitochondrial membranes and mutagnesis by ethidium bromide. J Supramol Struct 1972 0.89
80 Formation of yeast mitochondria. 3. Biochemical properties of mitochondria isolated from a cytoplasmic petite mutant. J Bioenerg 1970 0.89
81 Genetics and biogenesis of cytochrome b. Methods Enzymol 1983 0.88
82 Effects of mutagenic treatment by ethidium bromide on cellular and mitochondrial phenotype. Arch Biochem Biophys 1972 0.87
83 Mitochondrial gene expression in yeast: further studies of a self-splicing group II intron. Basic Life Sci 1986 0.86
84 Induction of respiration deficient mutants in Saccharomyces cerevisiae by berenil. I. Berenil, a novel, non-intercalating mutagen. Mol Gen Genet 1973 0.84
85 A premutational state induced in yeast by ethidium bromide. Biochem Biophys Res Commun 1971 0.84
86 Regulatory interaction between mitochondrial genes. II. Detailed characterization of novel mutants mapping within one cluster in the cob2 region. J Biol Chem 1979 0.84
87 Localization of genes for variant forms of mitochondrial proteins on mitochondrial DNA of Saccharomyces cerevisiae. J Mol Biol 1977 0.83
88 Mobility of two optional G + C-rich clusters of the var1 gene of yeast mitochondrial DNA. Genetics 1990 0.81
89 Mutant alleles of the MRS2 gene of yeast nuclear DNA suppress mutations in the catalytic core of a mitochondrial group II intron. J Mol Biol 1998 0.81
90 Suppression of mitochondrially-determined resistance to chloramphenicol and paromomycin by nuclear genes in Saccharomyces cerevisiae. Mol Gen Genet 1979 0.81
91 The mobile group I intron 3 alpha of the yeast mitochondrial COXI gene encodes a 35-kDa processed protein that is an endonuclease but not a maturase. J Biol Chem 1995 0.80
92 Introns in pieces. Curr Biol 1991 0.78
93 Induction of respiration deficient mutants in Saccharomyces cerevisiae by berenil. II. Characteristics of the process. Mol Gen Genet 1973 0.77
94 The mitochondrial genome of the fission yeast schizosaccharomyces pombe : I. isolation and physical mapping of mitochondrial DNA. Curr Genet 1983 0.76
95 Complex recognition site for the group I intron-encoded endonuclease I-SceII. Mol Cell Biol 1992 0.76
96 Letter: Mitochondrial morphology. Science 1974 0.75
97 Segregation of mitochondrial markers in yeast. Methods Enzymol 1979 0.75
98 Physical mapping of genetic determinants on yeast mitochondrial DNA affecting the apparent size of the Var 1 polypeptide. Curr Genet 1980 0.75
99 Respiration deficient mutants in the A+T-rich region on yeast mitochondrial DNA containing the var1 gene. Curr Genet 1982 0.75