PubRank

L H Mullenders

Author PubWeight™ 86.74‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Sequential assembly of the nucleotide excision repair factors in vivo. Mol Cell 2001 5.38
2 The genetic defect in Cockayne syndrome is associated with a defect in repair of UV-induced DNA damage in transcriptionally active DNA. Proc Natl Acad Sci U S A 1990 4.04
3 Domain structure, localization, and function of DNA polymerase eta, defective in xeroderma pigmentosum variant cells. Genes Dev 2001 2.53
4 Xeroderma pigmentosum complementation group C cells remove pyrimidine dimers selectively from the transcribed strand of active genes. Mol Cell Biol 1991 2.53
5 Deficient repair of the transcribed strand of active genes in Cockayne's syndrome cells. Nucleic Acids Res 1993 2.45
6 The residual repair capacity of xeroderma pigmentosum complementation group C fibroblasts is highly specific for transcriptionally active DNA. Nucleic Acids Res 1990 2.38
7 Transcription-coupled repair removes both cyclobutane pyrimidine dimers and 6-4 photoproducts with equal efficiency and in a sequential way from transcribed DNA in xeroderma pigmentosum group C fibroblasts. EMBO J 1995 2.04
8 Local UV-induced DNA damage in cell nuclei results in local transcription inhibition. EMBO Rep 2001 1.99
9 UV-induced DNA damage, repair, mutations and oncogenic pathways in skin cancer. J Photochem Photobiol B 2001 1.91
10 Analysis of the attachment of replicating DNA to a nuclear matrix in mammalian interphase nuclei. Nucleic Acids Res 1979 1.91
11 Strand specificity for UV-induced DNA repair and mutations in the Chinese hamster HPRT gene. Nucleic Acids Res 1991 1.68
12 UV-induced inhibition of transcription involves repression of transcription initiation and phosphorylation of RNA polymerase II. Proc Natl Acad Sci U S A 2000 1.57
13 Replication forks are associated with the nuclear matrix. Nucleic Acids Res 1990 1.55
14 The sensitivity of Cockayne's syndrome cells to DNA-damaging agents is not due to defective transcription-coupled repair of active genes. Mol Cell Biol 1996 1.41
15 Preferential repair of nuclear matrix associated DNA in xeroderma pigmentosum complementation group C. Mutat Res 1984 1.31
16 The role of nucleotide excision repair in protecting embryonic stem cells from genotoxic effects of UV-induced DNA damage. Nucleic Acids Res 1999 1.25
17 Differential effects of toxic metal compounds on the activities of Fpg and XPA, two zinc finger proteins involved in DNA repair. Carcinogenesis 2000 1.21
18 Analysis of repair of cyclobutane pyrimidine dimers and pyrimidine 6-4 pyrimidone photoproducts in transcriptionally active and inactive genes in Chinese hamster cells. J Biol Chem 1994 1.20
19 Interaction of arsenic(III) with nucleotide excision repair in UV-irradiated human fibroblasts. Carcinogenesis 1997 1.18
20 Characterization of defective nucleotide excision repair in XPC mutant mice. Mutat Res 1997 1.17
21 Defective global genome repair in XPC mice is associated with skin cancer susceptibility but not with sensitivity to UVB induced erythema and edema. J Invest Dermatol 1998 1.13
22 Transcription affects the rate but not the extent of repair of cyclobutane pyrimidine dimers in the human adenosine deaminase gene. J Biol Chem 1992 1.13
23 Association of nuclear DNA with a rapidly sedimenting structure. Biochem Biophys Res Commun 1977 1.13
24 (6-4) photoproducts and not cyclobutane pyrimidine dimers are the main UV-induced mutagenic lesions in Chinese hamster cells. Mutat Res 1992 1.08
25 Cells from XP-D and XP-D-CS patients exhibit equally inefficient repair of UV-induced damage in transcribed genes but different capacity to recover UV-inhibited transcription. Nucleic Acids Res 1999 1.08
26 Impact of global genome repair versus transcription-coupled repair on ultraviolet carcinogenesis in hairless mice. Cancer Res 2000 1.03
27 Distribution of u.v.-induced repair events in higher-order chromatin loops in human and hamster fibroblasts. Carcinogenesis 1986 1.00
28 Interference by toxic metal compounds with isolated zinc finger DNA repair proteins. Toxicol Lett 2000 0.98
29 Efficient synthesis of 32P-labeled single-stranded DNA probes using linear PCR; application of the method for analysis of strand-specific DNA repair. Mutat Res 1994 0.97
30 Age-dependent spontaneous mutagenesis in Xpc mice defective in nucleotide excision repair. Oncogene 2000 0.97
31 DNA repair of UV photoproducts and mutagenesis in human mitochondrial DNA. J Mol Biol 1997 0.96
32 Ultraviolet-induced cyclobutane pyrimidine dimers are selectively removed from transcriptionally active genes in the epidermis of the hairless mouse. Cancer Res 1993 0.94
33 Nickel(II) interferes with the incision step in nucleotide excision repair in mammalian cells. Cancer Res 1994 0.93
34 Differential role of transcription-coupled repair in UVB-induced G2 arrest and apoptosis in mouse epidermis. Proc Natl Acad Sci U S A 2000 0.93
35 Enhanced UV-induced mutagenesis in the UV61 cell line, the Chinese hamster homologue of Cockayne's syndrome B, is associated with defective transcription coupled repair of cyclobutane pyrimidine dimers. Mutat Res 1998 0.91
36 Strand-specific removal of cyclobutane pyrimidine dimers from the p53 gene in the epidermis of UVB-irradiated hairless mice. Oncogene 1994 0.90
37 The nature and repair of DNA lesions that lead to chromosomal aberrations induced by ionizing radiations. Mutat Res 1986 0.90
38 Cobalt(II) inhibits the incision and the polymerization step of nucleotide excision repair in human fibroblasts. Mutat Res 1997 0.89
39 Mutagenesis and carcinogenesis in nucleotide excision repair-deficient XPA knock out mice. Mutat Res 2000 0.88
40 Comparison of DNA loop size and super-coiled domain size in human cells. Mutat Res 1983 0.88
41 Induction of sister-chromatid exchanges by restriction endonucleases. Mutat Res 1985 0.87
42 DMBA-induced toxic and mutagenic responses vary dramatically between NER-deficient Xpa, Xpc and Csb mice. Carcinogenesis 2001 0.87
43 DNA repair characteristics and mutability of the UV-sensitive V79 Chinese hamster cell mutant V-B11 (complementation group 7). Mutagenesis 1991 0.86
44 The sensitivity of human fibroblasts to N-acetoxy-2-acetylaminofluorene is determined by the extent of transcription-coupled repair, and/or their capability to counteract RNA synthesis inhibition. Nucleic Acids Res 1996 0.85
45 Photodynamic effects of haematoporphyrin derivative on DNA repair in murine L929 fibroblasts. Biochem J 1987 0.85
46 Links between chromatin structure, DNA repair and chromosome fragility. Mutat Res 1998 0.84
47 Inhibition of repair of X-ray-induced DNA double-strand breaks in human lymphocytes exposed to sodium butyrate. Int J Radiat Biol 2000 0.83
48 Influence of DNA excision repair on UV-induced mutation spectra in Chinese hamster cells. Prog Clin Biol Res 1990 0.83
49 Impaired DNA repair capacity in skin fibroblasts from various hereditary cancer-prone syndromes. Mutat Res 1998 0.83
50 Analysis of the structure and spatial distribution of ultraviolet-induced DNA repair patches in human cells made in the presence of inhibitors of replicative synthesis. Biochim Biophys Acta 1985 0.82
51 Lack of transcription-coupled repair of acetylaminofluorene DNA adducts in human fibroblasts contrasts their efficient inhibition of transcription. J Biol Chem 1998 0.82
52 Transcription coupled repair and its impact on mutagenesis. Mutat Res 1998 0.82
53 The relationship between benzo[a]pyrene-induced mutagenesis and carcinogenesis in repair-deficient Cockayne syndrome group B mice. Cancer Res 2000 0.82
54 Construction of mouse chromosome-specific DNA libraries and their use for the detection of X-ray-induced aberrations. Int J Radiat Biol 1994 0.82
55 Nucleotide excision repair modulates the cytotoxic and mutagenic effects of N-n-butyl-N-nitrosourea in cultured mammalian cells as well as in mouse splenocytes in vivo. Mutagenesis 1999 0.81
56 Analysis of the distribution of DNA repair patches in the DNA-nuclear matrix complex from human cells. Biochim Biophys Acta 1983 0.81
57 Heat-shock treatment selectively affects induction and repair of cyclobutane pyrimidine dimers in transcriptionally active genes in ultraviolet-irradiated human fibroblasts. Radiat Res 1993 0.81
58 The use of streptavidin-coated magnetic beads and biotinylated antibodies to investigate induction and repair of DNA damage: analysis of repair patches in specific sequences of uv-irradiated human fibroblasts. Anal Biochem 1993 0.80
59 Opposite modifying effects of HR and NHEJ deficiency on cancer risk in Ptc1 heterozygous mouse cerebellum. Oncogene 2011 0.79
60 Selective inhibition of repair of active genes by hyperthermia is due to inhibition of global and transcription coupled repair pathways. Carcinogenesis 1995 0.79
61 Enzymatic activities involved in the DNA resynthesis step of nucleotide excision repair are firmly attached to chromatin. Nucleic Acids Res 1997 0.78
62 Mimosine is a potent clastogen in primary and transformed hamster fibroblasts but not in primary or transformed human lymphocytes. Mutagenesis 1995 0.78
63 Repair of UV-induced pyrimidine(6-4)pyrimidone photoproducts is selectively inhibited in transcriptionally active genes after heat treatment of human fibroblasts. Int J Radiat Biol 1995 0.78
64 Contributions from molecular/biochemical approaches in epidemiology to cancer risk assessment and prevention. Environ Health Perspect 1992 0.78
65 Composition and DNA-binding properties of the nuclear matrix proteins from mammalian cell nuclei. Biochim Biophys Acta 1982 0.78
66 Impact of radiation quality on the spectrum of induced chromosome exchange aberrations. Int J Radiat Biol 2001 0.78
67 Impairment of nucleotide excision repair by apoptosis in UV-irradiated mouse cells. Cancer Res 1998 0.78
68 Electrochemical detection and quantification of the acetylated and deacetylated C8-deoxyguanosine DNA adducts induced by 2-acetylaminofluorene. Anal Biochem 1997 0.77
69 Nickel(II) increases the sensitivity of V79 Chinese hamster cells towards cisplatin and transplatin by interference with distinct steps of DNA repair. Carcinogenesis 1999 0.77
70 Influence of bromodeoxyuridine substitution of thymidine on sister-chromatid exchanges and chromosomal aberrations induced by restriction endonucleases. Mutat Res 1986 0.76
71 DNA lesions and repair. Mutat Res 1996 0.76
72 Relationship between DNA-adduct formation, DNA repair, mutation frequency and mutation spectra. Ann Ist Super Sanita 1989 0.76
73 Gene and sequence specificity of DNA damage induction and repair: consequences for mutagenesis. Mutat Res 2001 0.76
74 Altered association of transcriptionally active DNA with the nuclear-matrix after heat shock. Int J Radiat Biol 1999 0.75
75 Restoration of nucleotide excision repair in a helicase-deficient XPD mutant from intragenic suppression by a trichothiodystrophy mutation. Mol Cell Biol 2001 0.75
76 Caffeine potentiates or protects against radiation-induced DNA and chromosomal damage in human lymphocytes depending on temperature and concentration. Mutat Res 1994 0.75
77 Effect of hyperthermia on DNA loop-size in HeLa S3 cells. Int J Radiat Biol Relat Stud Phys Chem Med 1988 0.75
78 Effects of pre-treatment with sodium butyrate on the frequencies of X-ray-induced chromosomal aberrations in human peripheral blood lymphocytes. Mutat Res 1985 0.75
79 Induction of DNA lesions, chromosomal aberrations, and G2 delay by bromo- and chlorodeoxyuridine. Basic Life Sci 1984 0.75
80 Elevated frequencies of benzo(a)pyrene-induced Hprt mutations in internal tissue of XPA-deficient mice. Cancer Res 1998 0.75
81 Mouse mismatch repair gene Msh2 is not essential for transcription-coupled repair of UV-induced cyclobutane pyrimidine dimers. Oncogene 2001 0.75
82 UV-induced alterations in the spatial distribution of the basal transcription factor TFIIH: an early event in nucleotide excision repair. Mutat Res 1998 0.75
83 DNA lesions, chromosomal aberrations and G2 delay in CHO cells cultured in medium containing bromo- or chloro-deoxyuridine. Mutat Res 1984 0.75