Published in JAMA on May 13, 1998
Discontinuation of statins in routine care settings: a cohort study. Ann Intern Med (2013) 5.87
Cost-effectiveness of 10-Year Risk Thresholds for Initiation of Statin Therapy for Primary Prevention of Cardiovascular Disease. JAMA (2015) 3.89
Factors affecting therapeutic compliance: A review from the patient's perspective. Ther Clin Risk Manag (2008) 3.75
Noncompliance with antihypertensive medications: the impact of depressive symptoms and psychosocial factors. J Gen Intern Med (2002) 2.85
Adherence to statin treatment and readmission of patients after myocardial infarction: a six year follow up study. Heart (2002) 2.83
New prescription medication gaps: a comprehensive measure of adherence to new prescriptions. Health Serv Res (2009) 2.63
Mail-order pharmacy use and adherence to diabetes-related medications. Am J Manag Care (2010) 2.51
Relationship of gender, depression, and health care delivery with antiretroviral adherence in HIV-infected drug users. J Gen Intern Med (2003) 2.18
Impact of a prescription copayment increase on lipid-lowering medication adherence in veterans. Circulation (2009) 2.06
Suboptimal statin adherence and discontinuation in primary and secondary prevention populations. J Gen Intern Med (2004) 2.01
Socioeconomic gradient in use of statins among Danish patients: population-based cross-sectional study. Br J Clin Pharmacol (2005) 1.89
Prevalence and predictors of antidepressant use in a cohort of pregnant women. BJOG (2007) 1.85
Medication adherence: a call for action. Am Heart J (2011) 1.85
Persistence with statins and onset of rheumatoid arthritis: a population-based cohort study. PLoS Med (2010) 1.66
Predictors of nonadherence to statins: a systematic review and meta-analysis. Ann Pharmacother (2010) 1.66
Undertreatment of hyperlipidemia in the secondary prevention of coronary artery disease. J Gen Intern Med (1999) 1.64
Statins and delirium during critical illness: a multicenter, prospective cohort study. Crit Care Med (2014) 1.60
Lack of adherence to lipid-lowering drug treatment. A comparison of utilization patterns in defined populations in Funen, Denmark and Bologna, Italy. Br J Clin Pharmacol (2000) 1.49
Trends in adherence to secondary prevention medications in elderly post-myocardial infarction patients. Pharmacoepidemiol Drug Saf (2008) 1.45
High persistence of statin use in a Danish population: compliance study 1993-1998. Br J Clin Pharmacol (2002) 1.42
Risk of congenital anomalies in pregnant users of statin drugs. Br J Clin Pharmacol (2007) 1.32
Persistence and determinants of statin therapy among middle-aged patients for primary and secondary prevention. Br J Clin Pharmacol (2005) 1.29
Strategies for coping in a complex world: adherence behavior among older adults with chronic illness. J Gen Intern Med (2007) 1.28
Coronary artery calcium in relation to initiation and continuation of cardiovascular preventive medications: The Multi-Ethnic Study of Atherosclerosis (MESA). Circ Cardiovasc Qual Outcomes (2010) 1.27
Cholesterol, triglycerides, and the Five-Factor Model of personality. Biol Psychol (2010) 1.24
Metabolic syndrome and insulin resistance: underlying causes and modification by exercise training. Compr Physiol (2013) 1.17
Treatment persistence and compliance with medications for chronic obstructive pulmonary disease. Can Respir J (2007) 1.16
Patients' perspectives on nonadherence to statin therapy: a focus-group study. Perm J (2010) 1.12
Interventions to improve adherence to lipid lowering medication. Cochrane Database Syst Rev (2004) 1.12
How should we measure medication adherence in clinical trials and practice? Ther Clin Risk Manag (2007) 1.12
Association between adherence to statin therapy and lipid control in Hong Kong Chinese patients at high risk of coronary heart disease. Br J Clin Pharmacol (2004) 1.10
Influence of socioeconomic status on clinical outcomes and quality of life after percutaneous coronary intervention. J Epidemiol Community Health (2006) 1.10
Use of statins and beta-blockers after acute myocardial infarction according to income and education. J Epidemiol Community Health (2007) 1.09
Impact of statin adherence on cardiovascular disease and mortality outcomes: a systematic review. Br J Clin Pharmacol (2014) 1.09
A cluster randomized controlled Trial to Evaluate an Ambulatory primary care Management program for patients with dyslipidemia: the TEAM study. CMAJ (2010) 1.09
Recycling expensive medication: why not? MedGenMed (2004) 1.08
Use of lipid-lowering drugs during 1991-98 in Northern Jutland, Denmark. Br J Clin Pharmacol (2001) 1.08
Adherence to statin or aspirin or both in patients with established cardiovascular disease: exploring healthy behaviour vs. drug effects and 10-year follow-up of outcome. Br J Clin Pharmacol (2008) 1.06
Persistence and determinants of statin therapy among middle-aged patients free of cardiovascular disease. Eur J Clin Pharmacol (2005) 1.05
Physician effectiveness in interventions to improve cardiovascular medication adherence: a systematic review. J Gen Intern Med (2010) 1.03
Peer education for secondary stroke prevention in inner-city minorities: design and methods of the prevent recurrence of all inner-city strokes through education randomized controlled trial. Contemp Clin Trials (2012) 1.02
Treating dyslipidaemia in primary care. The gap between policy and reality is large in the UK. BMJ (2000) 1.00
Apolipoprotein B versus lipoprotein lipids: vital lessons from the AFCAPS/TexCAPS trial. CMAJ (2001) 0.98
Use of inhaled corticosteroids during pregnancy and risk of pregnancy induced hypertension: nested case-control study. BMJ (2005) 0.98
Comparison of diet quality, physical activity and biochemical values of older adults either reporting or not reporting use of lipid-lowering medication. J Nutr Health Aging (2010) 0.97
Evaluation of the prescription and utilization patterns of statins in an Italian local health unit during the period 1994-2003. Eur J Clin Pharmacol (2007) 0.97
The role of usual source of care in cholesterol treatment. J Am Board Fam Med (2010) 0.96
Do patients' expectations influence their use of medications? Qualitative study. Can Fam Physician (2008) 0.96
Results of a national survey on OTC medicines, Part 2: Do pharmacists support switching prescription agents to over-the-counter status? Can Pharm J (Ott) (2012) 0.94
Family practice patients' adherence to statin medications. Can Fam Physician (2007) 0.94
Can improved prescription medication labeling influence adherence to chronic medications? An evaluation of the Target pharmacy label. J Gen Intern Med (2009) 0.93
Promoting knowledge of statins in patients with low health literacy using an audio booklet. Patient Prefer Adherence (2011) 0.92
A "hot" topic in dyslipidemia management--"how to beat a flush": optimizing niacin tolerability to promote long-term treatment adherence and coronary disease prevention. Mayo Clin Proc (2010) 0.91
A cross-national study of the persistence of antihypertensive medication use in the elderly. J Hypertens (2008) 0.91
Adherence with statins in a real-life setting is better when associated cardiovascular risk factors increase: a cohort study. BMC Cardiovasc Disord (2011) 0.91
Who receives lipid-lowering drugs: the effects of comorbidities and patient characteristics on treatment initiation. Br J Clin Pharmacol (2003) 0.89
Adherence to hormone therapy among women with breast cancer. BMC Cancer (2014) 0.89
Adherence to lipid-lowering treatment: the patient perspective. Patient Prefer Adherence (2012) 0.89
Initiation and persistence to statin treatment in patients with diabetes receiving glucose-lowering medications 1997- 2006. Open Cardiovasc Med J (2009) 0.89
Lipid-lowering drugs as primary prevention in general practice: do patients reach guideline goals and continue treatment? ADDITION Denmark. Scand J Prim Health Care (2011) 0.88
Effect of partial compliance on cardiovascular medication effectiveness. Heart (2002) 0.88
Discontinuation and switching of therapy after initiation of lipid-lowering drugs: the effects of comorbidities and patient characteristics. Br J Clin Pharmacol (2003) 0.87
The impact of reference pricing on switching behaviour and healthcare utilisation: the case of statins in Germany. Eur J Health Econ (2009) 0.87
Association of vitamin D and incident statin induced myalgia--a retrospective cohort study. PLoS One (2014) 0.86
Statin compliance in the Umbrian population. Eur J Clin Pharmacol (2003) 0.86
Comprehensive cardiovascular risk management--what does it mean in practice? Vasc Health Risk Manag (2007) 0.86
Pattern of statin use in southern italian primary care: can prescription databases be used for monitoring long-term adherence to the treatment? PLoS One (2014) 0.85
Assessing the adherence to and the therapeutic effectiveness of hypolipidemic agents in a population of patients in Brazil: a retrospective cohort study. Pharm Pract (Granada) (2014) 0.84
Twenty questions on atherosclerosis. Proc (Bayl Univ Med Cent) (2000) 0.84
Patient complexity and risk factor control among multimorbid patients with type 2 diabetes: results from the R2D2C2 study. Med Care (2013) 0.83
Factors explaining the gender disparity in lipid-lowering treatment goal attainment rate in Chinese patients with statin therapy. Lipids Health Dis (2012) 0.83
Randomized Trial of a Pharmacist-Delivered Intervention for Improving Lipid-Lowering Medication Adherence among Patients with Coronary Heart Disease. Cholesterol (2010) 0.83
Association of Medicare Part D medication out-of-pocket costs with utilization of statin medications. Health Serv Res (2012) 0.83
Effects of colesevelam HC1 on sterol and bile acid excretion in patients with type IIa hypercholesterolemia. Dig Dis Sci (2005) 0.81
Cost-effectiveness of rosuvastatin in comparison with generic atorvastatin and simvastatin in a Swedish population at high risk of cardiovascular events. Clinicoecon Outcomes Res (2012) 0.81
Teaching medication adherence in US colleges and schools of pharmacy. Am J Pharm Educ (2012) 0.80
Effects of an enhanced secondary prevention program for patients with heart disease: a prospective randomized trial. Can J Cardiol (2007) 0.80
Challenges in making therapeutic lifestyle changes among hypercholesterolemic African-American patients and their physicians. J Natl Med Assoc (2006) 0.80
Adherence to chronic cardiovascular therapies: persistence over the years and dose coverage. Br J Clin Pharmacol (2006) 0.79
Etanercept-Methotrexate Combination Therapy Initiators Have Greater Adherence and Persistence Than Triple Therapy Initiators With Rheumatoid Arthritis. Arthritis Care Res (Hoboken) (2015) 0.79
Factors of compliance in patients with hypercholesterolemia using rosuvastatin in primary care. Korean J Fam Med (2012) 0.78
Patient adherence and preference considerations in managing cardiovascular risk: focus on single pill and amlodipine/atorvastatin fixed combination. Patient Prefer Adherence (2009) 0.78
Rationale and design of the Study of a Tele-pharmacy Intervention for Chronic diseases to Improve Treatment adherence (STIC2IT): A cluster-randomized pragmatic trial. Am Heart J (2016) 0.78
Using stress testing to guide primary prevention of coronary heart disease among intermediate-risk patients: a cost-effectiveness analysis. Circulation (2011) 0.77
Reasons for discontinuation of lipid-lowering medications in patients with chronic kidney disease. Cardiorenal Med (2014) 0.77
Can differences in medical drug compliance between European countries be explained by social factors: analyses based on data from the European Social Survey, round 2. BMC Public Health (2009) 0.77
PCSK9 inhibition in the management of hyperlipidemia: focus on evolocumab. Vasc Health Risk Manag (2016) 0.77
Statin adherence and the risk of major coronary events in patients with diabetes: a nested case-control study. Br J Clin Pharmacol (2011) 0.77
Statin pharmacogenomics: opportunities to improve patient outcomes and healthcare costs with genetic testing. J Pers Med (2012) 0.77
Associations between patients' risk attitude and their adherence to statin treatment - a population based questionnaire and register study. BMC Fam Pract (2016) 0.76
Atherosclerotic vascular disease in systemic lupus erythematosus. J Natl Med Assoc (2002) 0.76
Anti-androgen prescribing patterns, patient treatment adherence and influencing factors; results from the nationwide PCBaSe Sweden. Eur J Clin Pharmacol (2012) 0.76
Treatment options for HCV nonresponders and relapse patients. Gastroenterol Hepatol (N Y) (2010) 0.76
Lowering low-density lipoprotein cholesterol levels in patients with type 2 diabetes mellitus. Int J Gen Med (2014) 0.76
Factors associated to persistence with hormonal therapy in women with breast cancer. Rev Saude Publica (2014) 0.76
The effect of placebo adherence on reducing cardiovascular mortality: a meta-analysis. Clin Res Cardiol (2013) 0.75
Unintentional Discontinuation of Chronic Medications for Seniors in Nursing Homes: Evaluation of a National Medication Reconciliation Accreditation Requirement Using a Population-Based Cohort Study. Medicine (Baltimore) (2015) 0.75
Economic evaluation of Cardio inCode®, a clinical-genetic function for coronary heart disease risk assessment. Appl Health Econ Health Policy (2013) 0.75
Reduction of bacteriuria and pyuria after ingestion of cranberry juice. JAMA (1994) 5.38
Association of inhaled corticosteroid use with cataract extraction in elderly patients. JAMA (1998) 4.44
The use of prescription claims databases in pharmacoepidemiological research: the accuracy and comprehensiveness of the prescription claims database in Québec. J Clin Epidemiol (1995) 3.99
Inhaled and nasal glucocorticoids and the risks of ocular hypertension or open-angle glaucoma. JAMA (1997) 3.47
3-Hydroxy-3-methylglutaryl coenzyme A reductase inhibitors and the risk of cancer: a nested case-control study. Arch Intern Med (2000) 3.31
HMG-CoA reductase inhibitors and the risk of hip fractures in elderly patients. JAMA (2000) 3.03
Questionable prescribing for elderly patients in Quebec. CMAJ (1994) 3.01
Do statins cause cancer? A meta-analysis of large randomized clinical trials. Am J Med (2001) 2.85
Noncompliance with congestive heart failure therapy in the elderly. Arch Intern Med (1994) 2.62
Compliance with antihypertensive therapy among elderly Medicaid enrollees: the roles of age, gender, and race. Am J Public Health (1996) 2.33
The effects of initial drug choice and comorbidity on antihypertensive therapy compliance: results from a population-based study in the elderly. Am J Hypertens (1997) 2.21
The risks and costs of multiple-generic substitution of topiramate. Neurology (2009) 2.07
Atrial fibrillation and stroke prevention with warfarin in the long-term care setting. Arch Intern Med (1997) 2.01
Treatment for glaucoma: adherence by the elderly. Am J Public Health (1993) 1.90
Definition of race and ethnicity in older people in Medicare and Medicaid. J Am Geriatr Soc (1999) 1.82
Hazardous benzodiazepine regimens in the elderly: effects of half-life, dosage, and duration on risk of hip fracture. Am J Psychiatry (2001) 1.80
Predictors of decreased renal function in patients with heart failure during angiotensin-converting enzyme inhibitor therapy: results from the studies of left ventricular dysfunction (SOLVD) Am Heart J (1999) 1.70
Zolpidem use and hip fractures in older people. J Am Geriatr Soc (2001) 1.68
Trends in medication choices for hypertension in the elderly. The decline of the thiazides. Hypertension (1995) 1.60
The use of the bootstrap statistical method for the pharmacoeconomic cost analysis of skewed data. Pharmacoeconomics (1998) 1.60
A longitudinal analysis of nursing home outcomes. Health Serv Res (1998) 1.56
Predictors of uncontrolled hypertension in ambulatory patients. Hypertension (2001) 1.49
A cost minimization model for the treatment of minor bleeding episodes in patients with haemophilia A and high-titre inhibitors. Haemophilia (2005) 1.46
Application of lag-time into exposure definitions to control for protopathic bias. Pharmacoepidemiol Drug Saf (2007) 1.44
Breast cancer screening for elderly women with and without comorbid conditions. A decision analysis model. Ann Intern Med (1992) 1.43
Use of geriatric assessment for older adults in the oncology setting: a systematic review. J Natl Cancer Inst (2012) 1.42
Glucocorticoids and the risk for initiation of hypoglycemic therapy. Arch Intern Med (1994) 1.41
Comparison of efficacy and cost among lipid-lowering agents in patients with primary hypercholesterolemia. Can J Cardiol (1998) 1.39
Osteoporosis among patients with type 1 and type 2 diabetes. Diabetes Metab (2008) 1.37
Agreement between drug treatment data and a discharge diagnosis of diabetes mellitus in the elderly. Am J Epidemiol (1999) 1.32
Rates of hypoglycemia in users of sulfonylureas. J Clin Epidemiol (1997) 1.27
Usefulness of probucol in treating primary hypercholesterolemia. Can Med Assoc J (1980) 1.27
The economic impact of factor VIII inhibitors in patients with haemophilia. Haemophilia (2004) 1.26
Initiation of antihypertensive treatment during nonsteroidal anti-inflammatory drug therapy. JAMA (1994) 1.24
Predictors of long-term persistence on statins in a subsidized clinical population. Value Health (2006) 1.22
Thiazide diuretics and the initiation of anti-gout therapy. J Clin Epidemiol (1997) 1.20
Using healthcare claims data for outcomes research and pharmacoeconomic analyses. Pharmacoeconomics (1999) 1.18
Risk of ocular hypertension or open-angle glaucoma in elderly patients on oral glucocorticoids. Lancet (1997) 1.17
Pharmacokinetics of lidocaine after prolonged intravenous infusions in uncomplicated myocardial infarction. Ann Intern Med (1977) 1.16
Aging, comorbidity, and reduced rates of drug treatment for diabetes mellitus. J Clin Epidemiol (1999) 1.16
Diet and probucol in lowering cholesterol concentrations. Additive effects on plasma cholesterol concentrations in patients with familial type ii hyperlipoproteinemia. Arch Intern Med (1977) 1.14
Adherence to guidelines for oral anticoagulation after venous thrombosis and pulmonary embolism. J Gen Intern Med (2000) 1.13
Association between the burden of disease and research funding by the Medical Research Council of Canada and the National Institutes of Health. A cross-sectional study. Clin Invest Med (2001) 1.12
An update on a systematic review of the use of geriatric assessment for older adults in oncology. Ann Oncol (2013) 1.11
Nonoccupational risk factors for carpal tunnel syndrome. J Gen Intern Med (1999) 1.11
Follow-up of loci from the International Genomics of Alzheimer's Disease Project identifies TRIP4 as a novel susceptibility gene. Transl Psychiatry (2014) 1.07
Predictors of persistence of use of the novel antidiabetic agent acarbose. Arch Intern Med (2001) 1.05
Shanghai trial of nifedipine in the elderly (STONE). J Hypertens (1996) 1.04
Age-related differences in in-hospital mortality and the use of thrombolytic therapy for acute myocardial infarction. CMAJ (2001) 1.04
Long-term continuous use of benzodiazepines by older adults in Quebec: prevalence, incidence and risk factors. J Am Geriatr Soc (2000) 1.03
Differences in persistence among different weekly oral bisphosphonate medications. Osteoporos Int (2008) 1.02
Gastrointestinal health care resource use and costs associated with nonsteroidal antiinflammatory drugs versus acetaminophen: retrospective cohort study of an elderly population. Arthritis Rheum (2000) 1.01
The relation between bisphosphonate use and non-union of fractures of the humerus in older adults. Osteoporos Int (2008) 0.97
Antidepressants and fracture risk in older adults: a comparative safety analysis. Clin Pharmacol Ther (2011) 0.96
Report of the Canadian Hypertension Society Consensus Conference: 3. Pharmacologic treatment of hypertensive disorders in pregnancy. CMAJ (1997) 0.96
Neuroleptic drug exposure and treatment of parkinsonism in the elderly: a case-control study. Am J Med (1995) 0.95
Autoinhibition in rabbit aortic strips after epinephrine. J Pharmacol Exp Ther (1967) 0.95
Phenotype genotype analysis in 15 patients presenting a congenital myasthenic syndrome due to mutations in DOK7. J Neurol (2009) 0.93
Immune tolerance induction in hemophilia patients with inhibitors: costly can be cheaper. Blood (2000) 0.92
The French Pompe registry. Baseline characteristics of a cohort of 126 patients with adult Pompe disease. Rev Neurol (Paris) (2013) 0.92
Clinical experience of cancer specialists and geriatricians involved in cancer care of older patients: A qualitative study. Crit Rev Oncol Hematol (2009) 0.91
Adherence to weekly oral bisphosphonate therapy: cost of wasted drugs and fractures. Osteoporos Int (2009) 0.91
Demographic and clinic characteristics of French patients treated with natalizumab in clinical practice. J Neurol (2009) 0.90
Does frailty predict hospitalization, emergency department visits, and visits to the general practitioner in older newly-diagnosed cancer patients? Results of a prospective pilot study. Crit Rev Oncol Hematol (2009) 0.90
Field-specific visual-evoked potentials: identifying field defects in vigabatrin-treated children. Neurology (2002) 0.90
Antihypertensive drug therapy and the initiation of treatment for diabetes mellitus. Ann Intern Med (1993) 0.89
The impact of ibuprofen on the efficacy of antihypertensive treatment with hydrochlorothiazide in elderly persons. J Gerontol A Biol Sci Med Sci (1996) 0.89
Effect of the duration of infusion on the disposition of lidocaine in dogs. J Pharmacol Exp Ther (1977) 0.89
Increased incidence of levodopa therapy following metoclopramide use. JAMA (1995) 0.89
Maternal cigarette smoking and fetal oxygen transport: a study of P50, 2,3-diphosphoglycerate, total hemoglobin, hematocrit, and type F hemoglobin in fetal blood. Pediatrics (1983) 0.88
Relapsing demyelinating disease affecting both the central and peripheral nervous systems. J Neurol Neurosurg Psychiatry (2008) 0.86
Exposure to allopurinol and the risk of cataract extraction in elderly patients. Arch Ophthalmol (1998) 0.86
Quality of life during the course of cancer treatment in older newly diagnosed patients. Results of a prospective pilot study. Ann Oncol (2010) 0.85
Estrogen replacement therapy: determinants of persistence with treatment. Obstet Gynecol (2001) 0.84
Selection of controls in database case-control studies: glucocorticoids and the risk of glaucoma. J Clin Epidemiol (1998) 0.83
Accuracy of postcontrast 3D turbo spin-echo MR sequence for the detection of enhanced inflammatory lesions in patients with multiple sclerosis. AJNR Am J Neuroradiol (2013) 0.82
Transplacental treatment of tachycardia-induced fetal heart failure with verapamil and amiodarone: a case report. Am J Obstet Gynecol (1985) 0.82
Effects of sotalol in twenty patients with cardiac arrhythmias. Int J Clin Pharmacol Biopharm (1977) 0.82
Cost of prescribed NSAID-related gastrointestinal adverse events in elderly patients. Br J Clin Pharmacol (2001) 0.82
Hirayama disease: an uncommon cause of distal upper extremity deficit. J Neuroradiol (2011) 0.82
Impact of a cost-sharing drug insurance plan on drug utilization among older people. J Am Geriatr Soc (2001) 0.82
Clinical and electrophysiological characteristics of neuropathy associated with Tangier disease. J Neurol (2011) 0.82
Topical glaucoma medications and cardiovascular risk in the elderly. Clin Pharmacol Ther (1994) 0.81