Published in Receptors Channels on January 01, 1997
Sequence comparison by sequence harmony identifies subtype-specific functional sites. Nucleic Acids Res (2006) 1.40
A sequence and structural study of transmembrane helices. J Comput Aided Mol Des (2001) 0.94
Construction of a sequence motif characteristic of aminergic G protein-coupled receptors. Protein Sci (2003) 0.92
Disentangling evolutionary signals: conservation, specificity determining positions and coevolution. Implication for catalytic residue prediction. BMC Bioinformatics (2012) 0.86
Protein-assisted pericyclic reactions: an alternate hypothesis for the action of quantal receptors. Biophys J (1999) 0.78
Errors in protein structures. Nature (1996) 18.70
Positioning hydrogen atoms by optimizing hydrogen-bond networks in protein structures. Proteins (1996) 5.83
Heterozygous germline mutations in the p53 homolog p63 are the cause of EEC syndrome. Cell (1999) 4.87
A database of protein structure families with common folding motifs. Protein Sci (1992) 4.77
The site of attachment in human rhinovirus 14 for antiviral agents that inhibit uncoating. Science (1986) 4.40
The atomic structure of Mengo virus at 3.0 A resolution. Science (1987) 4.34
GPCRDB: an information system for G protein-coupled receptors. Nucleic Acids Res (1998) 3.94
Conserved role of a complement-like protein in phagocytosis revealed by dsRNA knockout in cultured cells of the mosquito, Anopheles gambiae. Cell (2001) 3.58
New POU dimer configuration mediates antagonistic control of an osteopontin preimplantation enhancer by Oct-4 and Sox-2. Genes Dev (1998) 3.43
Optimizing the hydrogen-bond network in Poisson-Boltzmann equation-based pK(a) calculations. Proteins (2001) 3.03
Implications of the picornavirus capsid structure for polyprotein processing. Proc Natl Acad Sci U S A (1987) 2.99
PRODRG, a program for generating molecular topologies and unique molecular descriptors from coordinates of small molecules. J Comput Aided Mol Des (1996) 2.94
Homology modeling, model and software evaluation: three related resources. Bioinformatics (1998) 2.47
The PDBFINDER database: a summary of PDB, DSSP and HSSP information with added value. Comput Appl Biosci (1996) 2.46
Collecting and harvesting biological data: the GPCRDB and NucleaRDB information systems. Nucleic Acids Res (2001) 2.37
Prediction of protein conformational freedom from distance constraints. Proteins (1997) 2.30
Improving macromolecular electrostatics calculations. Protein Eng (1999) 2.29
Rubredoxin reductase of Pseudomonas oleovorans. Structural relationship to other flavoprotein oxidoreductases based on one NAD and two FAD fingerprints. J Mol Biol (1990) 2.21
Involvement of Asn-293 in stereospecific agonist recognition and in activation of the beta 2-adrenergic receptor. Proc Natl Acad Sci U S A (1996) 2.08
Pulmonary function after laparoscopic cholecystectomy in the elderly. Br J Surg (1996) 2.06
An active registry for bioinformatics web services. Bioinformatics (2009) 1.85
Engineering an enzyme to resist boiling. Proc Natl Acad Sci U S A (1998) 1.81
The essential dynamics of thermolysin: confirmation of the hinge-bending motion and comparison of simulations in vacuum and water. Proteins (1995) 1.70
Synergism with the coactivator OBF-1 (OCA-B, BOB-1) is mediated by a specific POU dimer configuration. Cell (2000) 1.69
Allosteric modulation of A(2A) adenosine receptors by amiloride analogues and sodium ions. Biochem Pharmacol (2000) 1.67
Autosomal recessive retinitis pigmentosa caused by mutations in the alpha subunit of rod cGMP phosphodiesterase. Nat Genet (1995) 1.61
Completion and refinement of 3-D homology models with restricted molecular dynamics: application to targets 47, 58, and 111 in the CASP modeling competition and posterior analysis. Proteins (2002) 1.59
Objectively judging the quality of a protein structure from a Ramachandran plot. Comput Appl Biosci (1997) 1.52
Molecular docking using surface complementarity. Proteins (1996) 1.44
Crystal structure of the p-hydroxybenzoate hydroxylase-substrate complex refined at 1.9 A resolution. Analysis of the enzyme-substrate and enzyme-product complexes. J Mol Biol (1989) 1.44
Correlated mutation analyses on very large sequence families. Chembiochem (2002) 1.36
The use of position-specific rotamers in model building by homology. Proteins (1995) 1.35
WIWS: a protein structure bioinformatics Web service collection. Nucleic Acids Res (2010) 1.32
MRS: a fast and compact retrieval system for biological data. Nucleic Acids Res (2005) 1.30
Suramin analogues as subtype-selective G protein inhibitors. Mol Pharmacol (1996) 1.27
Extreme stabilization of a thermolysin-like protease by an engineered disulfide bond. J Biol Chem (1997) 1.22
Role of ceramide 1 in the molecular organization of the stratum corneum lipids. J Lipid Res (1998) 1.20
Potential ligand-binding residues in rat olfactory receptors identified by correlated mutation analysis. Receptors Channels (1995) 1.19
Allosteric modulation of A(3) adenosine receptors by a series of 3-(2-pyridinyl)isoquinoline derivatives. Mol Pharmacol (2001) 1.18
Residues in the TATA-binding protein required to mediate a transcriptional response to retinoic acid in EC cells. Nature (1993) 1.16
A common step for signal transduction in G protein-coupled receptors. Trends Pharmacol Sci (1994) 1.15
Role of the N-terminal part of the coat protein in the assembly of cowpea chlorotic mottle virus. A 500 MHz proton nuclear magnetic resonance study and structural calculations. J Mol Biol (1986) 1.15
Avoidance of smoking: the impact of warning labels in Brazil. Tob Control (2008) 1.15
A very fast program for visualizing protein surfaces, channels and cavities. J Mol Graph (1989) 1.14
Site-directed mutagenesis studies of human A(2A) adenosine receptors: involvement of glu(13) and his(278) in ligand binding and sodium modulation. Biochem Pharmacol (2000) 1.11
Amyloids protect the silkmoth oocyte and embryo. FEBS Lett (2000) 1.10
Pharmacological analysis of ecto-ATPase inhibition: evidence for combined enzyme inhibition and receptor antagonism in P2X-purinoceptor ligands. Br J Pharmacol (1994) 1.10
Predicting local structural changes that result from point mutations. Protein Eng (1994) 1.10
Pudendal neuropathy is predictive of failure following anterior overlapping sphincteroplasty. Dis Colon Rectum (1998) 1.08
Role of monocytes in the up-regulation of the early activation marker CD69 on B and T murine lymphocytes induced by microbial mitogens. Scand J Immunol (1996) 1.08
Contributions of stimulus valence and arousal to visual activation during emotional perception. Neuroimage (2003) 1.06
Pharmacokinetic-pharmacodynamic relationship of the cardiovascular effects of adenosine A1 receptor agonist N6-cyclopentyladenosine in the rat. J Pharmacol Exp Ther (1994) 1.04
The interaction of class B G protein-coupled receptors with their hormones. Receptors Channels (1998) 1.04
Inhibition of receptor/G protein coupling by suramin analogues. Mol Pharmacol (1996) 1.04
Modeling of transmembrane seven helix bundles. Protein Eng (1993) 1.03
Stabilization of Bacillus stearothermophilus neutral protease by introduction of prolines. FEBS Lett (1993) 1.00
Heart rate variability under resting conditions in postmenopausal and young women. Braz J Med Biol Res (2001) 1.00
A low resolution model for the interaction of G proteins with G protein-coupled receptors. Protein Eng (1999) 0.99
Protein stabilization by hydrophobic interactions at the surface. Eur J Biochem (1994) 0.99
Conformational changes in the chaperonin GroEL: new insights into the allosteric mechanism. J Mol Biol (1999) 0.98
Anomalies of the CD8+ T cell pool in haemochromatosis: HLA-A3-linked expansions of CD8+CD28- T cells. Clin Exp Immunol (1997) 0.98
Ovarian recovery after stem cell transplantation. Bone Marrow Transplant (2007) 0.97
A novel class of adenosine A3 receptor ligands. 2. Structure affinity profile of a series of isoquinoline and quinazoline compounds. J Med Chem (1998) 0.97
Mechanism-based pharmacokinetic-pharmacodynamic modeling of the effects of N6-cyclopentyladenosine analogs on heart rate in rat: estimation of in vivo operational affinity and efficacy at adenosine A1 receptors. J Pharmacol Exp Ther (1997) 0.96
Mechanism-based pharmacokinetic-pharmacodynamic modeling of antilipolytic effects of adenosine A(1) receptor agonists in rats: prediction of tissue-dependent efficacy in vivo. J Pharmacol Exp Ther (1999) 0.96
Structural determinants of the stability of thermolysin-like proteinases. Nat Struct Biol (1995) 0.96
Structural and mutagenesis studies of leishmania triosephosphate isomerase: a point mutation can convert a mesophilic enzyme into a superstable enzyme without losing catalytic power. Protein Eng (1999) 0.95
Effects of age and physical activity on the autonomic control of heart rate in healthy men. Braz J Med Biol Res (2005) 0.95
Analysis of structural determinants of the stability of thermolysin-like proteases by molecular modelling and site-directed mutagenesis. Protein Eng (1996) 0.95
Study of interaction between agonists and asn293 in helix VI of human beta(2)-adrenergic receptor. Mol Pharmacol (1999) 0.94
A sequence and structural study of transmembrane helices. J Comput Aided Mol Des (2001) 0.94
AsteriX: a Web server to automatically extract ligand coordinates from figures in PDF articles. J Chem Inf Model (2012) 0.94
A steric and electrostatic comparison of three models for the agonist/antagonist binding site on the adenosine A1 receptor. J Med Chem (1992) 0.93
Why are A(2B) receptors low-affinity adenosine receptors? Mutation of Asn273 to Tyr increases affinity of human A(2B) receptor for 2-(1-Hexynyl)adenosine. Mol Pharmacol (2000) 0.92
The determinants of alpha-amylase pH-activity profiles. Protein Eng (2001) 0.92
Cloning and sequence analysis of the gene encoding human lymphocyte prolyl endopeptidase. Gene (1994) 0.92
Interleukin-6 upregulates neuronal adenosine A1 receptors: implications for neuromodulation and neuroprotection. Neuropsychopharmacology (2007) 0.90
Resilience and vagal tone predict cardiac recovery from acute social stress. Stress (2007) 0.90
Heavier-than-air flying machines are impossible. FEBS Lett (2004) 0.90
Kinetic analysis of the interaction of the phosphatidylcholine exchange protein with unilamellar vesicels and multilamellar liposomes. Eur J Biochem (1979) 0.90
Converse modulation of IRP1 and IRP2 by immunological stimuli in murine RAW 264.7 macrophages. J Biol Chem (1998) 0.89
The role of calcium ions in the stability and instability of a thermolysin-like protease. Protein Sci (2011) 0.88
The beta subunit of human rod photoreceptor cGMP-gated cation channel is generated from a complex transcription unit. FEBS Lett (1996) 0.88
Quality of life in chronic kidney disease. Nefrologia (2011) 0.87
Study of the interaction between aryloxypropanolamines and Asn386 in helix VII of the human 5-hydroxytryptamine1A receptor. Mol Pharmacol (1997) 0.87
The role of the second and third extracellular loops of the adenosine A1 receptor in activation and allosteric modulation. Biochem Pharmacol (2012) 0.87
Adenosine derivatives with N6-alkyl, -alkylamine or -alkyladenosine substituents as probes for the A1-receptor. FEBS Lett (1987) 0.87
Highly sensitive C-reactive protein and male gender are independently related to the severity of coronary disease in patients with metabolic syndrome and an acute coronary event. Braz J Med Biol Res (2010) 0.87
Validation of nuclear magnetic resonance structures of proteins and nucleic acids: hydrogen geometry and nomenclature. Proteins (1999) 0.87
Contribution of the C-terminal amino acid to the stability of Bacillus subtilis neutral protease. Protein Eng (1990) 0.86
Are interpretations of video defecographies reliable and reproducible? Int J Colorectal Dis (1997) 0.86
Evaluation of bone marrow mesenchymal stem cell standard cryopreservation procedure efficiency. Transplant Proc (2008) 0.86
Drug design for ever, from hype to hope. J Comput Aided Mol Des (2012) 0.85
Characterization of excitatory prostanoid receptors in the human umbilical artery in vitro. Br J Pharmacol (1999) 0.85
Extracellular adenosine-induced apoptosis in mouse neuroblastoma cells: studies on involvement of adenosine receptors and adenosine uptake. Biochem Pharmacol (2001) 0.85