P L Bergsagel

Author PubWeight™ 65.01‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 International Myeloma Working Group molecular classification of multiple myeloma: spotlight review. Leukemia 2009 4.91
2 The t(4;14) translocation in myeloma dysregulates both FGFR3 and a novel gene, MMSET, resulting in IgH/MMSET hybrid transcripts. Blood 1998 3.69
3 Frequent translocation t(4;14)(p16.3;q32.3) in multiple myeloma is associated with increased expression and activating mutations of fibroblast growth factor receptor 3. Nat Genet 1997 3.11
4 Diverse karyotypic abnormalities of the c-myc locus associated with c-myc dysregulation and tumor progression in multiple myeloma. Proc Natl Acad Sci U S A 2000 2.81
5 Genetic aberrations and survival in plasma cell leukemia. Leukemia 2008 2.69
6 Activated fibroblast growth factor receptor 3 is an oncogene that contributes to tumor progression in multiple myeloma. Blood 2001 2.48
7 Frequent dysregulation of the c-maf proto-oncogene at 16q23 by translocation to an Ig locus in multiple myeloma. Blood 1998 2.36
8 Multiple myeloma: increasing evidence for a multistep transformation process. Blood 1998 2.29
9 Dysregulation of cyclin D1 by translocation into an IgH gamma switch region in two multiple myeloma cell lines. Blood 1996 2.21
10 Genetic events in the pathogenesis of multiple myeloma. Best Pract Res Clin Haematol 2007 2.14
11 Clinical and biological implications of MYC activation: a common difference between MGUS and newly diagnosed multiple myeloma. Leukemia 2011 2.12
12 WWOX, the FRA16D gene, behaves as a suppressor of tumor growth. Cancer Res 2001 2.12
13 Benzene and multiple myeloma: appraisal of the scientific evidence. Blood 1999 2.05
14 Cyclophosphamide, bortezomib and dexamethasone induction for newly diagnosed multiple myeloma: high response rates in a phase II clinical trial. Leukemia 2009 1.97
15 Pomalidomide (CC4047) plus low dose dexamethasone (Pom/dex) is active and well tolerated in lenalidomide refractory multiple myeloma (MM). Leukemia 2010 1.77
16 Prognostic value of chromosome 1q21 gain by fluorescent in situ hybridization and increase CKS1B expression in myeloma. Leukemia 2006 1.71
17 A practical guide to defining high-risk myeloma for clinical trials, patient counseling and choice of therapy. Leukemia 2007 1.66
18 A kinder, gentler way: control of the proliferative tumor compartment, not cosmetic complete response, should be the goal of myeloma therapy. Leukemia 2008 1.43
19 Prognostic factors for hyperdiploid-myeloma: effects of chromosome 13 deletions and IgH translocations. Leukemia 2006 1.39
20 Compromised stem cell mobilization following induction therapy with lenalidomide in myeloma. Leukemia 2008 1.24
21 Ectopic expression of fibroblast growth factor receptor 3 promotes myeloma cell proliferation and prevents apoptosis. Blood 2000 1.21
22 Genome-wide studies in multiple myeloma identify XPO1/CRM1 as a critical target validated using the selective nuclear export inhibitor KPT-276. Leukemia 2013 1.21
23 Translocation t(4;14) retains prognostic significance even in the setting of high-risk molecular signature. Leukemia 2007 1.18
24 The myeloma-associated oncogene fibroblast growth factor receptor 3 is transforming in hematopoietic cells. Blood 2001 1.17
25 Insertion of excised IgH switch sequences causes overexpression of cyclin D1 in a myeloma tumor cell. Mol Cell 1999 1.16
26 Frequent inactivation of the cyclin-dependent kinase inhibitor p18 by homozygous deletion in multiple myeloma cell lines: ectopic p18 expression inhibits growth and induces apoptosis. Leukemia 2002 1.15
27 Cyclin D3 at 6p21 is dysregulated by recurrent chromosomal translocations to immunoglobulin loci in multiple myeloma. Blood 2001 1.15
28 Concurrent activation of a novel putative transforming gene, myeov, and cyclin D1 in a subset of multiple myeloma cell lines with t(11;14)(q13;q32). Blood 2000 1.09
29 Correlation between array-comparative genomic hybridization-defined genomic gains and losses and survival: identification of 1p31-32 deletion as a prognostic factor in myeloma. Leukemia 2010 0.97
30 Selective expression of one c-myc allele in two human myeloma cell lines. Cancer Res 1996 0.95
31 Diagnostic evaluation of t(4;14) in multiple myeloma and evidence for clonal evolution. Leukemia 2007 0.92
32 CD34+ cells in the blood of patients with multiple myeloma express CD19 and IgH mRNA and have patient-specific IgH VDJ gene rearrangements. Blood 1997 0.91
33 Expression and mutation status of candidate kinases in multiple myeloma. Leukemia 2007 0.87
34 Recurrent immunoglobulin gene translocations identify distinct molecular subtypes of myeloma. Ann Oncol 2000 0.87
35 Dysregulation of c-myc in multiple myeloma. Curr Top Microbiol Immunol 1997 0.85
36 Multiple myeloma. Hematology Am Soc Hematol Educ Program 2001 0.84
37 Maintained rules of development in a mouse B-cell tumor. Leukemia 2005 0.84
38 Preclinical screening of histone deacetylase inhibitors combined with ABT-737, rhTRAIL/MD5-1 or 5-azacytidine using syngeneic Vk*MYC multiple myeloma. Cell Death Dis 2013 0.83
39 Ploidy status rarely changes in myeloma patients at disease progression. Leuk Res 2005 0.81
40 Coordinate silencing of myeloma-specific genes in myeloma x T lymphoma hybrids. J Immunol 1993 0.81
41 Initiation and maintenance of multiple myeloma. Semin Hematol 1999 0.77
42 Identification of consensus genes expressed in plasmacytomas but not B lymphomas. Curr Top Microbiol Immunol 1990 0.75