Published in J Cell Physiol on July 01, 1998
The Emerging Hallmarks of Cancer Metabolism. Cell Metab (2016) 2.32
Glutamine sensitivity analysis identifies the xCT antiporter as a common triple-negative breast tumor therapeutic target. Cancer Cell (2013) 1.73
SLC1A5 mediates glutamine transport required for lung cancer cell growth and survival. Clin Cancer Res (2012) 1.46
Cancer cell lines release glutamate into the extracellular environment. Clin Exp Metastasis (2009) 1.00
Expression of the pro-angiogenic factors vascular endothelial growth factor and interleukin-8/CXCL8 by human breast carcinomas is responsive to nutrient deprivation and endoplasmic reticulum stress. Mol Cancer (2004) 0.99
Glutamine as indispensable nutrient in oncology: experimental and clinical evidence. Eur J Nutr (2009) 0.93
Glutamine promotes ovarian cancer cell proliferation through the mTOR/S6 pathway. Endocr Relat Cancer (2015) 0.87
Novel therapeutic targets of tumor metabolism. Cancer J (2015) 0.82
Inhibitors of glutamate release from breast cancer cells; new targets for cancer-induced bone-pain. Sci Rep (2015) 0.82
Characterisation of G418-induced metabolic load in recombinant CHO and BHK cells: effect on the activity and expression of central metabolic enzymes. Cytotechnology (2003) 0.81
IL4 receptor α mediates enhanced glucose and glutamine metabolism to support breast cancer growth. Biochim Biophys Acta (2015) 0.81
Influence of oral glutamine supplementation on survival outcomes of patients treated with concurrent chemoradiotherapy for locally advanced non-small cell lung cancer. BMC Cancer (2012) 0.80
Mitochondrial thiol modification by a targeted electrophile inhibits metabolism in breast adenocarcinoma cells by inhibiting enzyme activity and protein levels. Redox Biol (2016) 0.76
Glutamine regulates amino acid transport and glutathione levels in a human neuroblastoma cell line. Pediatr Surg Int (2005) 0.75
Metabolomic characterisation of the effects of oncogenic PIK3CA transformation in a breast epithelial cell line. Sci Rep (2017) 0.75
Epigenetic silencing of microRNA-137 enhances ASCT2 expression and tumor glutamine metabolism. Oncogenesis (2017) 0.75
Surgical management of phyllodes tumors. Arch Surg (1999) 2.16
The effect of surgery and grade on outcome of gastrointestinal stromal tumors. Arch Surg (2001) 2.05
Prognosis and survival in patients with gastrointestinal tract carcinoid tumors. Ann Surg (1999) 1.92
Cloning and analysis of unique human glutaminase isoforms generated by tissue-specific alternative splicing. Physiol Genomics (1999) 1.84
Glutamine metabolism by the intestinal tract. JPEN J Parenter Enteral Nutr (1985) 1.71
Effect of dietary glutamate on chemotherapy-induced immunosuppression. Nutrition (1999) 1.39
The essence of mentoring in academic surgery. J Surg Oncol (2000) 1.35
Modulation of cellular proliferation alters glutamine transport and metabolism in human hepatoma cells. Ann Surg (1994) 1.34
Perception of breast cancer risk among women in breast center and primary care settings: correlation with age and family history of breast cancer. Surgery (1996) 1.33
Prophylactic glutamine protects the intestinal mucosa from radiation injury. Cancer (1990) 1.32
Influence of progressive tumor growth on glutamine metabolism in skeletal muscle and kidney. Ann Surg (1993) 1.24
Mechanisms governing the expression of the enzymes of glutamine metabolism--glutaminase and glutamine synthetase. J Nutr (2001) 1.21
Postoperative alteration of arteriovenous exchange of amino acids across the gastrointestinal tract. Surgery (1983) 1.18
Glutamine-enriched diets support muscle glutamine metabolism without stimulating tumor growth. J Surg Res (1990) 1.06
Glutamine. World J Surg (2000) 1.05
Successful laparoscopic fundoplication in children with ventriculoperitoneal shunts. Surg Endosc (2001) 1.05
Glutamine transport in isolated human hepatocytes and transformed liver cells. Hepatology (1995) 1.04
Multimodality management of Merkel cell carcinoma. Arch Surg (1999) 1.04
Glutamine as a regulator of DNA and protein biosynthesis in human solid tumor cell lines. Ann Surg (1996) 1.01
Relationship between colorectal liver metastases and CEA levels in gallbladder bile. Ann Surg (1989) 1.01
Outcome of patients with melanoma and histologically negative sentinel lymph nodes. Arch Surg (1999) 1.00
Radiation-induced sarcomas of the chest wall. Cancer (1986) 1.00
Intestinal glutamine metabolism after massive small bowel resection. Am J Surg (1990) 1.00
The effects of glutamine-enriched total parenteral nutrition on tumor growth and host tissues. Ann Surg (1992) 0.99
Growth hormone enhances amino acid uptake by the human small intestine. Ann Surg (1994) 0.96
Glutamine preserves gut glutathione levels during intestinal ischemia/reperfusion. J Surg Res (1994) 0.95
Outcomes in a series of 103 retroperitoneal sarcomas. Eur J Surg Oncol (2006) 0.94
Intestinal consumption of intravenously administered fuels. JPEN J Parenter Enteral Nutr (1985) 0.94
Glutamine metabolism in sepsis and infection. J Nutr (2001) 0.94
Adaptive alterations in cellular metabolism with malignant transformation. Ann Surg (1998) 0.93
Total parenteral nutrition decreases luminal mucous gel and increases permeability of small intestine. JPEN J Parenter Enteral Nutr (1994) 0.93
Adaptive regulation of alanine transport in hepatic plasma membrane vesicles from the endotoxin-treated rat. J Surg Res (1991) 0.91
Does information from axillary dissection change treatment in clinically node-negative patients with breast cancer? An algorithm for assessment of impact of axillary dissection. Ann Surg (1997) 0.91
Effects of glucocorticoids on glutamine metabolism in visceral organs. Metabolism (1985) 0.91
Tumor necrosis factor stimulates amino acid transport in plasma membrane vesicles from rat liver. J Clin Invest (1993) 0.91
Tumor regulation of hepatic glutamine metabolism. JPEN J Parenter Enteral Nutr (1991) 0.90
Surgical management of primary cutaneous melanomas of the hands and feet. Ann Surg (1997) 0.90
Regulation of glutamine synthetase in human breast carcinoma cells and experimental tumors. Surgery (1997) 0.90
Alanyl-glutamine-supplemented parenteral nutrition increases luminal mucus gel and decreases permeability in the rat small intestine. JPEN J Parenter Enteral Nutr (1999) 0.90
Characterization of L-arginine transport by pulmonary artery endothelial cells. Am J Physiol (1993) 0.90
Effect of total parenteral nutrition on amino acid and glucose transport by the human small intestine. Ann Surg (1993) 0.89
Adaptive regulation of amino acid transport in nutrient-deprived human hepatomas. Am J Surg (1996) 0.89
The effect of surgical site infections on outcomes and resource utilization after liver transplantation. Surgery (2001) 0.89
Induction of cytokine-induced neutrophil chemoattractant (CINC) mRNA in the lungs of septic rats. J Trauma (1996) 0.89
Growth hormone regulates amino acid transport in human and rat liver. Ann Surg (1992) 0.89
Brush border transport of glutamine and other substrates during sepsis and endotoxemia. Ann Surg (1991) 0.89
Endotoxin and renal glutamine metabolism. Arch Surg (1991) 0.89
Lymphedema after sentinel lymph node biopsy for cutaneous melanoma: a report of 5 cases. Arch Dermatol (2000) 0.88
Bronchial reconstruction for bronchopulmonary foregut malformation: a case report. J Pediatr Surg (1995) 0.88
Rat liver endothelial cell glutamine transporter and glutaminase expression contrast with parenchymal cells. Am J Physiol (1999) 0.87
Multiwell 14CO2-capture assay for evaluation of substrate oxidation rates of cells in culture. Biotechniques (1998) 0.87
Accelerated lung amino acid release in hyperdynamic septic surgical patients. Arch Surg (1990) 0.87
Expression of NOS II and its role in experimental small bowel ulceration in rats. Surgery (1999) 0.87
The effects of endotoxin on the splanchnic metabolism of glutamine and related substrates. J Trauma (1991) 0.87
Mechanisms of accelerated hepatic glutamine efflux in the tumour-bearing rat. Surg Oncol (1992) 0.86
Arginine transport in human liver. Characterization and effects of nitric oxide synthase inhibitors. Ann Surg (1993) 0.86
Glutamine synthetase expression in muscle is regulated by transcriptional and posttranscriptional mechanisms. Am J Physiol (1999) 0.86
Parenteral nutrition and metabolic observations in cancer. Nutr Clin Pract (1988) 0.85
TNF-stimulated arginine transport by human vascular endothelium requires activation of protein kinase C. Ann Surg (1995) 0.85
Tissue-specific regulation of glutamine synthetase gene expression in acute pancreatitis is confirmed by using interleukin-1 receptor knockout mice. Surgery (1996) 0.85
Endoscopic variceal ligation in the management of gastroesophageal varices in postoperative biliary atresia. J Pediatr Surg (1998) 0.85
Glutamine synthetase expression in rat lung is regulated by protein stability. Am J Physiol (1998) 0.85
Glucocorticoids regulate rat glutamine synthetase expression in a tissue-specific manner. J Surg Res (1995) 0.84
Glutamine transport and human hepatocellular transformation. JPEN J Parenter Enteral Nutr (1999) 0.84
Adaptive regulation in skeletal muscle glutamine metabolism in endotoxin-treated rats. J Trauma (1992) 0.84
Role of intestinal mucus on the uptake of latex beads by Peyer's patches and on their transport to mesenteric lymph nodes in rats. JPEN J Parenter Enteral Nutr (1999) 0.84
Does preoperative radiation therapy enhance the probability of local control and survival in high-risk distal rectal cancer? Ann Surg (1992) 0.84
Dietary modulation of small intestinal glutamine transport in intestinal brush border membrane vesicles of rats. J Surg Res (1990) 0.84
Nitric oxide synthase inhibitor attenuates inflammatory lesions in the skin of zinc-deficient rats. Nutrition (2000) 0.83
Detection of a functional promoter/enhancer in an intron-less human gene encoding a glutamine synthetase-like enzyme. Gene (1995) 0.83
Cytokines regulate endotoxin stimulation of endothelial cell arginine transport. Surgery (1995) 0.83
Protein kinase C regulates nutrient uptake and growth in hepatoma cells. Surgery (1998) 0.83
No margin, no mission. J Surg Res (1996) 0.83
Regulation of small intestinal glutamine transport by epidermal growth factor. Surgery (1993) 0.83
Induction of nitric oxide synthase in rat intestine by interleukin-1alpha may explain diarrhea associated with zinc deficiency. J Nutr (1997) 0.83
Characteristics of infantile cases of congenital dilatation of the bile duct. J Pediatr Surg (1998) 0.83
Characterization and growth factor stimulation of L-arginine transport in a human colon cancer cell line. Ann Surg Oncol (1995) 0.82
Glucocorticoids regulate glutamine synthetase expression in lung epithelial cells. Am J Physiol (1996) 0.82
Developmental changes in distribution of the mucous gel layer and intestinal permeability in rat small intestine. JPEN J Parenter Enteral Nutr (1997) 0.82
Characterization of L-glutamine transport by pulmonary artery endothelial cells. Am J Physiol (1991) 0.82
Endotoxin stimulates lymphocyte glutaminase expression. Arch Surg (1993) 0.82
Attenuation of the endotoxin-stimulated increase in hepatic amino acid transport with a glucocorticoid receptor antagonist. J Surg Res (1995) 0.82
Na(+)-dependent glutamine transport in the liver of tumour-bearing rats. Surg Oncol (1993) 0.81
Revision laparoscopy for incarcerated hernia at a 5-mm trocar site following pediatric laparoscopic surgery. Surg Laparosc Endosc Percutan Tech (1999) 0.81
Hepatic glutamine transporter activation in burn injury: role of amino acids and phosphatidylinositol-3-kinase. Am J Physiol Gastrointest Liver Physiol (2000) 0.81
Phorbol esters rapidly attenuate glutamine uptake and growth in human colon carcinoma cells. J Surg Res (2000) 0.81
Inhibition of pulmonary microvascular endothelial glutamine transport by glucocorticoids and endotoxin. JPEN J Parenter Enteral Nutr (1996) 0.81