Published in Biochim Biophys Acta on June 15, 1998
Chemogenomic profiling: identifying the functional interactions of small molecules in yeast. Proc Natl Acad Sci U S A (2004) 5.10
The Smith-Lemli-Opitz syndrome. J Med Genet (2000) 3.05
A visual screen of a GFP-fusion library identifies a new type of nuclear envelope membrane protein. J Cell Biol (1999) 2.69
A critical role of sterols in embryonic patterning and meristem programming revealed by the fackel mutants of Arabidopsis thaliana. Genes Dev (2000) 1.93
FACKEL is a sterol C-14 reductase required for organized cell division and expansion in Arabidopsis embryogenesis. Genes Dev (2000) 1.92
Malformation syndromes caused by disorders of cholesterol synthesis. J Lipid Res (2010) 1.88
Subdomain-specific localization of CLIMP-63 (p63) in the endoplasmic reticulum is mediated by its luminal alpha-helical segment. J Cell Biol (2001) 1.60
Autosomal recessive HEM/Greenberg skeletal dysplasia is caused by 3 beta-hydroxysterol delta 14-reductase deficiency due to mutations in the lamin B receptor gene. Am J Hum Genet (2003) 1.40
Biosynthesis of cholesterol and other sterols. Chem Rev (2011) 1.30
Topological and mutational analysis of Saccharomyces cerevisiae Ste14p, founding member of the isoprenylcysteine carboxyl methyltransferase family. Mol Biol Cell (2001) 1.20
Lamin B receptor: multi-tasking at the nuclear envelope. Nucleus (2011) 1.13
Specific nuclear envelope transmembrane proteins can promote the location of chromosomes to and from the nuclear periphery. Genome Biol (2013) 1.11
Inner nuclear membrane proteins: impact on human disease. Chromosoma (2012) 1.05
Mouse neutrophils lacking lamin B-receptor expression exhibit aberrant development and lack critical functional responses. Exp Hematol (2008) 1.02
Induction of a massive endoplasmic reticulum and perinuclear space expansion by expression of lamin B receptor mutants and the related sterol reductases TM7SF2 and DHCR7. Mol Biol Cell (2009) 0.98
Tissue specificity in the nuclear envelope supports its functional complexity. Nucleus (2013) 0.96
Preservation of genes involved in sterol metabolism in cholesterol auxotrophs: facts and hypotheses. PLoS One (2008) 0.94
The lamin B receptor under transcriptional control of C/EBPepsilon is required for morphological but not functional maturation of neutrophils. Hum Mol Genet (2008) 0.94
The nucleoporin ELYS/Mel28 regulates nuclear envelope subdomain formation in HeLa cells. Nucleus (2012) 0.93
Cyclopia (synophthalmia) in Smith-Lemli-Opitz syndrome: First reported case and consideration of mechanism. Am J Med Genet C Semin Med Genet (2010) 0.90
Mutations causing Greenberg dysplasia but not Pelger anomaly uncouple enzymatic from structural functions of a nuclear membrane protein. Nucleus (2010) 0.89
Lamin B receptor regulates the growth and maturation of myeloid progenitors via its sterol reductase domain: implications for cholesterol biosynthesis in regulating myelopoiesis. J Immunol (2011) 0.85
Structure of an integral membrane sterol reductase from Methylomicrobium alcaliphilum. Nature (2014) 0.83
Dosage effect of zero to three functional LBR-genes in vivo and in vitro. Nucleus (2010) 0.81
Sterol metabolism. Arabidopsis Book (2002) 0.81
The Lamin B receptor is essential for cholesterol synthesis and perturbed by disease-causing mutations. Elife (2016) 0.80
Cloning of an emopamil-binding protein (EBP)-like protein that lacks sterol delta8-delta7 isomerase activity. Biochem J (2003) 0.80
A novel role for Tm7sf2 gene in regulating TNFα expression. PLoS One (2013) 0.80
The inner nuclear membrane: simple, or very complex? EMBO J (2001) 0.78
Nuclear hormone receptors put immunity on sterols. Eur J Immunol (2015) 0.76
The danger of "multi-tasking": LBR out of control. Nucleus (2010) 0.75
Pelger-Huët anomaly and Greenberg skeletal dysplasia: LBR-associated diseases of cholesterol metabolism. Rare Dis (2016) 0.75
Lamin B Receptor: Interplay between Structure, Function and Localization. Cells (2017) 0.75
Monoallelically expressed gene related to p53 at 1p36, a region frequently deleted in neuroblastoma and other human cancers. Cell (1997) 7.27
Isolation and structure of the endogenous agonist of opioid receptor-like ORL1 receptor. Nature (1995) 6.72
In-gel digestion of proteins for internal sequence analysis after one- or two-dimensional gel electrophoresis. Anal Biochem (1992) 6.44
Intramolecular masking of nuclear import signal on NF-AT4 by casein kinase I and MEKK1. Cell (1998) 2.57
Monocyte chemotactic protein 3 is a most effective basophil- and eosinophil-activating chemokine. J Exp Med (1994) 2.29
The 100-kDa neurotensin receptor is gp95/sortilin, a non-G-protein-coupled receptor. J Biol Chem (1998) 1.84
Structure of the metJBLF cluster in Escherichia coli K12. Sequence of the metB structural gene and of the 5'- and 3'-flanking regions of the metBL operon. J Biol Chem (1983) 1.77
Role of a new mammalian gene family in the biosynthesis of very long chain fatty acids and sphingolipids. J Cell Biol (2000) 1.70
Cloning and expression of a complementary DNA encoding a high affinity human neurotensin receptor. FEBS Lett (1993) 1.62
Cloning of the human IL-13R alpha1 chain and reconstitution with the IL4R alpha of a functional IL-4/IL-13 receptor complex. FEBS Lett (1997) 1.57
An amino-terminal variant of the central cannabinoid receptor resulting from alternative splicing. J Biol Chem (1995) 1.54
Nucleotide sequence of metF, the E. coli structural gene for 5-10 methylene tetrahydrofolate reductase and of its control region. Nucleic Acids Res (1983) 1.53
Interleukin-13 alters the activation state of murine macrophages in vitro: comparison with interleukin-4 and interferon-gamma. Eur J Immunol (1994) 1.52
Morphologic techniques for the study of brown adipose tissue and white adipose tissue. Methods Mol Biol (2001) 1.51
Primary structure and functional expression of mouse pituitary and human brain corticotrophin releasing factor receptors. FEBS Lett (1993) 1.48
Innate recognition of bacteria in human milk is mediated by a milk-derived highly expressed pattern recognition receptor, soluble CD14. J Exp Med (2000) 1.48
Human 76p: A new member of the gamma-tubulin-associated protein family. J Cell Biol (1999) 1.44
Cloning and characterization of a specific interleukin (IL)-13 binding protein structurally related to the IL-5 receptor alpha chain. J Biol Chem (1996) 1.43
Interleukin 13 is a B cell stimulating factor. J Exp Med (1994) 1.41
Biological activity of chitosan: ultrastructural study. Biomaterials (1988) 1.39
The two soluble forms of the lipopolysaccharide receptor, CD14: characterization and release by normal human monocytes. Eur J Immunol (1994) 1.36
Molecular cloning of a levocabastine-sensitive neurotensin binding site. FEBS Lett (1996) 1.32
Soluble CD14 acts as a negative regulator of human T cell activation and function. Eur J Immunol (1999) 1.32
High affinity RGD-binding sites at the plasma membrane of Arabidopsis thaliana links the cell wall. Plant J (1998) 1.30
The immunosuppressant SR 31747 blocks cell proliferation by inhibiting a steroid isomerase in Saccharomyces cerevisiae. Mol Cell Biol (1996) 1.30
Preconditioning does not prevent postischemic dysfunction in aging heart. J Am Coll Cardiol (1996) 1.28
Cloning and sequencing of PYBP, a pyrimidine-rich specific single strand DNA-binding protein. Nucleic Acids Res (1991) 1.27
beta-Endorphin: characteristics of binding sites in the rat brain. Biochem Biophys Res Commun (1979) 1.26
Molecular cloning, expression and function of the murine CB2 peripheral cannabinoid receptor. Biochim Biophys Acta (1996) 1.23
The related cytokines interleukin-13 and interleukin-4 are distinguished by differential production and differential effects on T lymphocytes. Eur Cytokine Netw (1997) 1.20
Macrophage-inactivating IL-13 suppresses experimental autoimmune encephalomyelitis in rats. J Immunol (1994) 1.18
Cloning and expression in Escherichia coli of the gene encoding Aspergillus flavus urate oxidase. J Biol Chem (1992) 1.17
Studies on eosinophilic meningitis. 3. Epidemiologic and clinical observations on Pacific islands and the possible etiologic role of Angiostrongylus cantonensis. Am J Epidemiol (1967) 1.16
Release from a human monocyte-like cell line of two different soluble forms of the lipopolysaccharide receptor, CD14. Eur J Immunol (1993) 1.15
Cloning and sequencing of the 52K cathepsin D complementary deoxyribonucleic acid of MCF7 breast cancer cells and mapping on chromosome 11. Mol Endocrinol (1988) 1.15
Attenuation of collagen-induced arthritis in mice by treatment with vector cells engineered to secrete interleukin-13. Eur J Immunol (1996) 1.15
Purification and characterization of the human SR 31747A-binding protein. A nuclear membrane protein related to yeast sterol isomerase. J Biol Chem (1997) 1.13
Congestive heart failure predicts the development of non-insulin-dependent diabetes mellitus in the elderly. The Osservatorio Geriatrico Regione Campania Group. Diabetes Metab (1997) 1.12
Interleukin 13 inhibits human immunodeficiency virus type 1 production in primary blood-derived human macrophages in vitro. J Exp Med (1993) 1.11
Structural features of the central cannabinoid CB1 receptor involved in the binding of the specific CB1 antagonist SR 141716A. J Biol Chem (1996) 1.09
Activation of transcription of a yeast gene in E. coli by an IS5 element. Nature (1982) 1.09
Characterization of two cloned human CB1 cannabinoid receptor isoforms. J Pharmacol Exp Ther (1996) 1.08
Cutting edge: human B cell function is regulated by interaction with soluble CD14: opposite effects on IgG1 and IgE production. J Immunol (2000) 1.08
Cannabinoid receptor interactions with the antagonists SR 141716A and SR 144528. Life Sci (1999) 1.07
Purification to homogeneity and NH2-terminal amino acid sequence of a novel interleukin 1 species derived from a human B cell line. J Immunol (1986) 1.07
Evidence for nerve growth factor-potentiating activities of the nonpeptidic compound SR 57746A in PC12 cells. J Neurochem (1995) 1.04
Characterization and comparison of the interleukin 13 receptor with the interleukin 4 receptor on several cell types. J Biol Chem (1995) 1.04
Identification of proteins of the yeast protein map using genetically manipulated strains and peptide-mass fingerprinting. Yeast (1996) 1.03
Construction and physical mapping of plasmids containing the metJBLF gene cluster of E. coli K12. Mol Gen Genet (1982) 1.03
An Italian epidemiological multicentre study of nocturnal enuresis. Br J Urol (1998) 1.01
Emopamil-binding protein, a mammalian protein that binds a series of structurally diverse neuroprotective agents, exhibits delta8-delta7 sterol isomerase activity in yeast. J Biol Chem (1996) 1.01
Topological analysis of the peripheral benzodiazepine receptor in yeast mitochondrial membranes supports a five-transmembrane structure. J Biol Chem (1998) 1.00
Colocalization of sterol isomerase and sigma(1) receptor at endoplasmic reticulum and nuclear envelope level. Eur J Biochem (1999) 0.99
Diazepam binding inhibitor is a paracrine/autocrine regulator of Leydig cell proliferation and steroidogenesis: action via peripheral-type benzodiazepine receptor and independent mechanisms. Endocrinology (1993) 0.99
Human recombinant dimeric IL-6 binds to its receptor as detected by anti-IL-6 monoclonal antibodies. Mol Immunol (1991) 0.99
Anti-inflammatory effects of peripheral benzodiazepine receptor ligands in two mouse models of inflammation. Eur J Pharmacol (2000) 0.98
Self-organized neural maps of human protein sequences. Protein Sci (1994) 0.95
Neurotensin is an antagonist of the human neurotensin NT2 receptor expressed in Chinese hamster ovary cells. Eur J Pharmacol (1998) 0.95
Mutational analysis and molecular modelling of the antagonist SR 144528 binding site on the human cannabinoid CB(2) receptor. Eur J Pharmacol (2000) 0.95
Protocadherin 15 (PCDH15): a new secreted isoform and a potential marker for NK/T cell lymphomas. Oncogene (2006) 0.95
High-level production of a peroxisomal enzyme: Aspergillus flavus uricase accumulates intracellularly and is active in Saccharomyces cerevisiae. Gene (1992) 0.94
Topography of the Leydig cell mitochondrial peripheral-type benzodiazepine receptor. Mol Cell Endocrinol (1994) 0.93
Interleukin-13 induces expression and release of interleukin-1 decoy receptor in human polymorphonuclear cells. J Biol Chem (1994) 0.93
Identification of a C-terminal tripeptide motif involved in the control of rapid proteasomal degradation of c-Fos proto-oncoprotein during the G(0)-to-S phase transition. Oncogene (2001) 0.93
Antiproliferative effects of SR31747A in animal cell lines are mediated by inhibition of cholesterol biosynthesis at the sterol isomerase step. Eur J Biochem (1998) 0.93
Sterol metabolism and ERG2 gene regulation in the yeast Saccharomyces cerevisiae. FEBS Lett (2000) 0.93
N-acetyl-heparosan lyase of Escherichia coli K5: gene cloning and expression. J Bacteriol (1996) 0.92
Role of interleukin 6 in the inflammatory response after cataract surgery. An experimental and clinical study. Arch Ophthalmol (1991) 0.92
Dual intracellular signaling pathways mediated by the human cannabinoid CB1 receptor. Eur J Pharmacol (1999) 0.92
Flexibility of the murine prion protein and its Asp178Asn mutant investigated by molecular dynamics simulations. J Mol Graph Model (2001) 0.92
Evidence for the presence of beta 3-adrenergic receptor mRNA in the human brain. Brain Res Mol Brain Res (1995) 0.91
A 3D model of the peripheral benzodiazepine receptor and its implication in intra mitochondrial cholesterol transport. J Mol Graph (1993) 0.90
Determination of the three-dimensional structure of CC chemokine monocyte chemoattractant protein 3 by 1H two-dimensional NMR spectroscopy. Biochemistry (1997) 0.90
Experimental gene therapy of cancer using tumor cells engineered to secrete interleukin-13. Eur J Immunol (1995) 0.89
Human interleukin-13 activates the interleukin-4-dependent transcription factor NF-IL4 sharing a DNA binding motif with an interferon-gamma-induced nuclear binding factor. FEBS Lett (1994) 0.89
Interleukin-13 inhibits protein kinase C-triggered respiratory burst in human monocytes. Role of calcium and cyclic AMP. J Biol Chem (1995) 0.88
Human recombinant interleukin-1 beta isolated from Escherichia coli by simple osmotic shock. Gene (1990) 0.88
Internal homologies in the two aspartokinase-homoserine dehydrogenases of Escherichia coli K-12. Proc Natl Acad Sci U S A (1984) 0.88
Tissue distribution and cellular localization of the levocabastine-sensitive neurotensin receptor mRNA in adult rat brain. Brain Res Mol Brain Res (1998) 0.88
Beta-Endorphin: dissociation of receptor binding activity from analgesic potency. Proc Natl Acad Sci U S A (1980) 0.88
Molecular cloning of a human beta 3-adrenergic receptor cDNA. FEBS Lett (1993) 0.88
beta-Endorphin: characteristics of binding sites in a neuroblastoma--glioma hybrid cell. Proc Natl Acad Sci U S A (1981) 0.88
Site-directed mutagenesis of the peripheral benzodiazepine receptor: identification of amino acids implicated in the binding site of Ro5-4864. Mol Pharmacol (1994) 0.87
Detection and biochemical characteristics of the receptor for complexes of soluble CD14 and bacterial lipopolysaccharide. J Immunol (1997) 0.87
Purification and first characterization of the secreted and cellular 52-kDa proteins regulated by estrogens in human-breast cancer cells. Eur J Biochem (1986) 0.87
Nocturnal enuresis in the adolescent: a neglected problem. BJU Int (2002) 0.87