Published in J Membr Biol on July 15, 1998
Properties of lipid microdomains in a muscle cell membrane visualized by single molecule microscopy. EMBO J (2000) 5.54
Caveolins, liquid-ordered domains, and signal transduction. Mol Cell Biol (1999) 4.70
Dynamics of putative raft-associated proteins at the cell surface. J Cell Biol (2004) 4.52
Lipid rafts function in biosynthetic delivery of proteins to the cell surface in yeast. Proc Natl Acad Sci U S A (2000) 4.14
Relationship of lipid rafts to transient confinement zones detected by single particle tracking. Biophys J (2002) 3.70
Coherent anti-stokes Raman scattering imaging of axonal myelin in live spinal tissues. Biophys J (2005) 3.62
Resistance of cell membranes to different detergents. Proc Natl Acad Sci U S A (2003) 3.57
Lipid rafts: heterogeneity on the high seas. Biochem J (2004) 3.46
Ternary phase diagram of dipalmitoyl-PC/dilauroyl-PC/cholesterol: nanoscopic domain formation driven by cholesterol. Biophys J (2001) 3.35
Visualizing lipid structure and raft domains in living cells with two-photon microscopy. Proc Natl Acad Sci U S A (2003) 3.17
Partitioning of Thy-1, GM1, and cross-linked phospholipid analogs into lipid rafts reconstituted in supported model membrane monolayers. Proc Natl Acad Sci U S A (2001) 3.12
Plasma membranes are poised for activation of raft phase coalescence at physiological temperature. Proc Natl Acad Sci U S A (2008) 2.97
Virus entry, assembly, budding, and membrane rafts. Microbiol Mol Biol Rev (2003) 2.68
Crosslinking a lipid raft component triggers liquid ordered-liquid disordered phase separation in model plasma membranes. Proc Natl Acad Sci U S A (2005) 2.60
Analysis of detergent-resistant membranes in Arabidopsis. Evidence for plasma membrane lipid rafts. Plant Physiol (2004) 2.55
The effect of cholesterol on the lateral diffusion of phospholipids in oriented bilayers. Biophys J (2003) 2.50
Cholesterol depletion induces large scale domain segregation in living cell membranes. Proc Natl Acad Sci U S A (2001) 2.41
A comprehensive comparison of transmembrane domains reveals organelle-specific properties. Cell (2010) 2.35
Condensation of the plasma membrane at the site of T lymphocyte activation. J Cell Biol (2005) 2.33
Critical role for cholesterol in Lyn-mediated tyrosine phosphorylation of FcepsilonRI and their association with detergent-resistant membranes. J Cell Biol (1999) 2.30
Condensed complexes, rafts, and the chemical activity of cholesterol in membranes. Proc Natl Acad Sci U S A (2000) 2.26
The challenge of lipid rafts. J Lipid Res (2008) 2.23
Lipid landscapes and pipelines in membrane homeostasis. Nature (2014) 2.09
PGP4, an ATP binding cassette P-glycoprotein, catalyzes auxin transport in Arabidopsis thaliana roots. Plant Cell (2005) 2.08
Raft association of SNAP receptors acting in apical trafficking in Madin-Darby canine kidney cells. Proc Natl Acad Sci U S A (1999) 1.95
Single-molecule imaging of the H-ras membrane-anchor reveals domains in the cytoplasmic leaflet of the cell membrane. Biophys J (2004) 1.95
Integrin-mediated adhesion regulates membrane order. J Cell Biol (2006) 1.92
The size of lipid rafts: an atomic force microscopy study of ganglioside GM1 domains in sphingomyelin/DOPC/cholesterol membranes. Biophys J (2002) 1.91
In vivo imaging and differential localization of lipid-modified GFP-variant fusions in embryonic stem cells and mice. Genesis (2006) 1.85
Cholesterol does not induce segregation of liquid-ordered domains in bilayers modeling the inner leaflet of the plasma membrane. Biophys J (2001) 1.85
Accumulation of raft lipids in T-cell plasma membrane domains engaged in TCR signalling. EMBO J (2009) 1.84
Functional roles for fatty acylated amino-terminal domains in subcellular localization. Mol Biol Cell (1999) 1.82
Role for human immunodeficiency virus type 1 membrane cholesterol in viral internalization. J Virol (2002) 1.81
SHP-1 and SHP-2 in T cells: two phosphatases functioning at many levels. Immunol Rev (2009) 1.78
Imaging barriers to diffusion by pair correlation functions. Biophys J (2009) 1.77
The LAT story: a tale of cooperativity, coordination, and choreography. Cold Spring Harb Perspect Biol (2010) 1.77
Characterization of lipid rafts from Medicago truncatula root plasma membranes: a proteomic study reveals the presence of a raft-associated redox system. Plant Physiol (2007) 1.73
Cystic fibrosis transmembrane conductance regulator and caveolin-1 regulate epithelial cell internalization of Pseudomonas aeruginosa. Am J Physiol Cell Physiol (2009) 1.72
Dissecting the role of the golgi complex and lipid rafts in biosynthetic transport of cholesterol to the cell surface. Proc Natl Acad Sci U S A (2000) 1.67
Annexins in cell membrane dynamics. Ca(2+)-regulated association of lipid microdomains. J Cell Biol (2000) 1.67
Electron spin resonance characterization of liquid ordered phase of detergent-resistant membranes from RBL-2H3 cells. Biophys J (1999) 1.55
Sphingomyelin-enriched microdomains at the Golgi complex. Mol Biol Cell (2001) 1.55
Lipids and membrane microdomains in HIV-1 replication. Virus Res (2009) 1.51
Lipid packing drives the segregation of transmembrane helices into disordered lipid domains in model membranes. Proc Natl Acad Sci U S A (2011) 1.50
Sterol biosynthesis is required for heat resistance but not extracellular survival in leishmania. PLoS Pathog (2014) 1.48
Lipid dynamics and domain formation in model membranes composed of ternary mixtures of unsaturated and saturated phosphatidylcholines and cholesterol. Biophys J (2003) 1.48
Cytoskeleton-dependent membrane domain segregation during neutrophil polarization. Mol Biol Cell (2001) 1.47
Use of cyclodextrins to monitor transbilayer movement and differential lipid affinities of cholesterol. Biophys J (2001) 1.46
Vacuolar uptake of host components, and a role for cholesterol and sphingomyelin in malarial infection. EMBO J (2000) 1.45
Human immunodeficiency virus type 1 assembly and lipid rafts: Pr55(gag) associates with membrane domains that are largely resistant to Brij98 but sensitive to Triton X-100. J Virol (2003) 1.43
Role of lipid rafts in E-cadherin-- and HGF-R/Met--mediated entry of Listeria monocytogenes into host cells. J Cell Biol (2004) 1.42
Sphingolipid partitioning into ordered domains in cholesterol-free and cholesterol-containing lipid bilayers. Biophys J (2003) 1.41
Cross-correlation analysis of inner-leaflet-anchored green fluorescent protein co-redistributed with IgE receptors and outer leaflet lipid raft components. Biophys J (2001) 1.41
N-terminal protein acylation confers localization to cholesterol, sphingolipid-enriched membranes but not to lipid rafts/caveolae. Mol Biol Cell (2001) 1.39
Different sphingolipids show differential partitioning into sphingolipid/cholesterol-rich domains in lipid bilayers. Biophys J (2000) 1.37
CD40 signaling in human dendritic cells is initiated within membrane rafts. EMBO J (2000) 1.37
Pattern formation during T-cell adhesion. Biophys J (2004) 1.37
"Entropic traps" in the kinetics of phase separation in multicomponent membranes stabilize nanodomains. Biophys J (2006) 1.34
Distribution of ganglioside GM1 in L-alpha-dipalmitoylphosphatidylcholine/cholesterol monolayers: a model for lipid rafts. Biophys J (2000) 1.31
Cholesterol accumulation sequesters Rab9 and disrupts late endosome function in NPC1-deficient cells. J Biol Chem (2006) 1.31
Lipid rafts, fluid/fluid phase separation, and their relevance to plasma membrane structure and function. Semin Cell Dev Biol (2007) 1.31
GPI anchoring leads to sphingolipid-dependent retention of endocytosed proteins in the recycling endosomal compartment. EMBO J (2001) 1.31
Are all n-3 polyunsaturated fatty acids created equal? Lipids Health Dis (2009) 1.29
The lateral diffusion of selectively aggregated peptides in giant unilamellar vesicles. Biophys J (2003) 1.26
Caveolae structure and function. J Cell Mol Med (2008) 1.26
The N-Myc down regulated Gene1 (NDRG1) Is a Rab4a effector involved in vesicular recycling of E-cadherin. PLoS One (2007) 1.26
Fluorescence-based evaluation of the partitioning of lipids and lipidated peptides into liquid-ordered lipid microdomains: a model for molecular partitioning into "lipid rafts". Biophys J (2000) 1.25
Insights into the role of specific lipids in the formation and delivery of lipid microdomains to the plasma membrane of plant cells. Plant Physiol (2006) 1.24
Cholesterol dependent recruitment of di22:6-PC by a G protein-coupled receptor into lateral domains. Biophys J (2000) 1.24
GnRH signaling, the gonadotrope and endocrine control of fertility. Front Neuroendocrinol (2010) 1.23
Functional role of lipid raft microdomains in cyclic nucleotide-gated channel activation. Mol Pharmacol (2004) 1.21
Have we become overly reliant on lipid rafts? Talking Point on the involvement of lipid rafts in T-cell activation. EMBO Rep (2008) 1.18
Palmitoylation of the murine leukemia virus envelope protein is critical for lipid raft association and surface expression. J Virol (2002) 1.16
Evidence for coupled biogenesis of yeast Gap1 permease and sphingolipids: essential role in transport activity and normal control by ubiquitination. Mol Biol Cell (2007) 1.16
Lateral organization and domain formation in a two-component lipid membrane system. Biophys J (2001) 1.15
Lipid raft disruption by cholesterol depletion enhances influenza A virus budding from MDCK cells. J Virol (2007) 1.15
PER1 is required for GPI-phospholipase A2 activity and involved in lipid remodeling of GPI-anchored proteins. Mol Biol Cell (2006) 1.14
Regulation of T-cell receptor signalling by membrane microdomains. Immunology (2004) 1.14
Changes in free and esterified cholesterol: hallmarks of acute renal tubular injury and acquired cytoresistance. Am J Pathol (2000) 1.13
The role of cholesterol in rod outer segment membranes. Prog Lipid Res (2005) 1.13
The tetraspan protein EMP2 modulates the surface expression of caveolins and glycosylphosphatidyl inositol-linked proteins. Mol Biol Cell (2004) 1.13
Targeting of pseudorabies virus structural proteins to axons requires association of the viral Us9 protein with lipid rafts. PLoS Pathog (2008) 1.12
Domain formation induced by the adsorption of charged proteins on mixed lipid membranes. Biophys J (2004) 1.12
Use of cyclodextrin for AFM monitoring of model raft formation. Biophys J (2004) 1.11
Lipids and the ocular lens. J Lipid Res (2010) 1.10
Glutamate-binding affinity of Drosophila metabotropic glutamate receptor is modulated by association with lipid rafts. Proc Natl Acad Sci U S A (2003) 1.10
Proving lipid rafts exist: membrane domains in the prokaryote Borrelia burgdorferi have the same properties as eukaryotic lipid rafts. PLoS Pathog (2013) 1.09
T-cell antigen receptor triggering and lipid rafts: a matter of space and time scales. Talking Point on the involvement of lipid rafts in T-cell activation. EMBO Rep (2008) 1.09
Visualization of detergent solubilization of membranes: implications for the isolation of rafts. Biophys J (2007) 1.09
Mitochondria do not contain lipid rafts, and lipid rafts do not contain mitochondrial proteins. J Lipid Res (2009) 1.08
Ordered raft domains induced by outer leaflet sphingomyelin in cholesterol-rich asymmetric vesicles. Biophys J (2015) 1.07
Scavenger receptor BI (SR-BI) clustered on microvillar extensions suggests that this plasma membrane domain is a way station for cholesterol trafficking between cells and high-density lipoprotein. Mol Biol Cell (2003) 1.07
The Role of Lipids in Retrovirus Replication. Viruses (2010) 1.07
Probing HIV-1 membrane liquid order by Laurdan staining reveals producer cell-dependent differences. J Biol Chem (2009) 1.07
Sorting of GPI-anchored proteins into ER exit sites by p24 proteins is dependent on remodeled GPI. J Cell Biol (2011) 1.06
The diversity of the liquid ordered (Lo) phase of phosphatidylcholine/cholesterol membranes: a variable temperature multinuclear solid-state NMR and x-ray diffraction study. Biophys J (2006) 1.05
Renal cholesterol accumulation: a durable response after acute and subacute renal insults. Am J Pathol (2001) 1.05
Signaling through sphingolipid microdomains of the plasma membrane: the concept of signaling platform. Glycoconj J (2001) 1.05
Quantitative proteomics reveals a dynamic association of proteins to detergent-resistant membranes upon elicitor signaling in tobacco. Mol Cell Proteomics (2009) 1.04
Functions of lipid rafts in biological membranes. Annu Rev Cell Dev Biol (1998) 14.83
Structure and function of sphingolipid- and cholesterol-rich membrane rafts. J Biol Chem (2000) 9.96
Interactions between saturated acyl chains confer detergent resistance on lipids and glycosylphosphatidylinositol (GPI)-anchored proteins: GPI-anchored proteins in liposomes and cells show similar behavior. Proc Natl Acad Sci U S A (1994) 5.61
Structure of detergent-resistant membrane domains: does phase separation occur in biological membranes? Biochem Biophys Res Commun (1997) 3.67
Parallax method for direct measurement of membrane penetration depth utilizing fluorescence quenching by spin-labeled phospholipids. Biochemistry (1987) 3.32
The effect of sterol structure on membrane lipid domains reveals how cholesterol can induce lipid domain formation. Biochemistry (2000) 3.11
Cholesterol and sphingolipid enhance the Triton X-100 insolubility of glycosylphosphatidylinositol-anchored proteins by promoting the formation of detergent-insoluble ordered membrane domains. J Biol Chem (1998) 2.78
Refolding of an integral membrane protein. Denaturation, renaturation, and reconstitution of intact bacteriorhodopsin and two proteolytic fragments. J Biol Chem (1981) 2.03
Mitral valve prolapse in one hundred presumably healthy young females. Circulation (1976) 2.02
Fluorimetric determination of critical micelle concentration avoiding interference from detergent charge. Anal Biochem (1984) 1.93
Fluorescence quenching in model membranes. 1. Characterization of quenching caused by a spin-labeled phospholipid. Biochemistry (1981) 1.62
Extension of the parallax analysis of membrane penetration depth to the polar region of model membranes: use of fluorescence quenching by a spin-label attached to the phospholipid polar headgroup. Biochemistry (1993) 1.60
Denaturation and renaturation of bacteriorhodopsin in detergents and lipid-detergent mixtures. J Biol Chem (1982) 1.60
Deep penetration of a portion of Escherichia coli SecA protein into model membranes is promoted by anionic phospholipids and by partial unfolding. J Biol Chem (1992) 1.49
Effect of pH on the conformation of diphtheria toxin and its implications for membrane penetration. Biochemistry (1985) 1.48
Reliability and reproducibility of two dimensional echocardiograph measurement of the stenotic mitral valve orifice area. Am J Cardiol (1979) 1.47
Determination of the depth of BODIPY probes in model membranes by parallax analysis of fluorescence quenching. Biochim Biophys Acta (1998) 1.37
Fluorescence quenching in model membranes. 2. Determination of local lipid environment of the calcium adenosinetriphosphatase from sarcoplasmic reticulum. Biochemistry (1981) 1.37
Transmembrane orientation of hydrophobic alpha-helices is regulated both by the relationship of helix length to bilayer thickness and by the cholesterol concentration. Biochemistry (1997) 1.36
Interaction of diphtheria toxin T domain with molten globule-like proteins and its implications for translocation. Science (1999) 1.32
Identification of shallow and deep membrane-penetrating forms of diphtheria toxin T domain that are regulated by protein concentration and bilayer width. J Biol Chem (1997) 1.22
Anchoring of tryptophan and tyrosine analogs at the hydrocarbon-polar boundary in model membrane vesicles: parallax analysis of fluorescence quenching induced by nitroxide-labeled phospholipids. Biochemistry (1995) 1.21
Control of the transmembrane orientation and interhelical interactions within membranes by hydrophobic helix length. Biochemistry (1999) 1.20
Identifying transmembrane states and defining the membrane insertion boundaries of hydrophobic helices in membrane-inserted diphtheria toxin T domain. J Biol Chem (1998) 1.20
Groups with polar characteristics can locate at both shallow and deep locations in membranes: the behavior of dansyl and related probes. Biochemistry (1998) 1.19
Spectroscopic and ionization properties of N-(7-nitrobenz-2-oxa-1,3-diazol-4-yl)-labeled lipids in model membranes. Biochim Biophys Acta (1988) 1.18
Location of diphenylhexatriene (DPH) and its derivatives within membranes: comparison of different fluorescence quenching analyses of membrane depth. Biochemistry (1998) 1.16
Regeneration of the native bacteriorhodopsin structure from two chymotryptic fragments. J Biol Chem (1983) 1.16
Diphtheria toxin forms pores of different sizes depending on its concentration in membranes: probable relationship to oligomerization. J Membr Biol (1999) 1.15
Calibration of the parallax fluorescence quenching method for determination of membrane penetration depth: refinement and comparison of quenching by spin-labeled and brominated lipids. Biochemistry (1992) 1.14
The location of fluorescence probes with charged groups in model membranes. Biochim Biophys Acta (1998) 1.04
Conformation and model membrane interactions of diphtheria toxin fragment A. J Biol Chem (1988) 1.00
A convenient and sensitive fluorescence assay for phospholipid vesicles using diphenylhexatriene. Anal Biochem (1978) 1.00
Phosphorus NMR analysis of phospholipids in detergents. J Lipid Res (1979) 0.97
Similarity of the conformation of diphtheria toxin at high temperature to that in the membrane-penetrating low-pH state. Proc Natl Acad Sci U S A (1986) 0.96
Membrane translocation of charged residues at the tips of hydrophobic helices in the T domain of diphtheria toxin. Biochemistry (1999) 0.95
Leukoencephalopathy in normal and pathologic aging: 1. CT of brain lucencies. AJNR Am J Neuroradiol (1986) 0.92
The effects of polar and/or ionizable residues in the core and flanking regions of hydrophobic helices on transmembrane conformation and oligomerization. Biochemistry (2000) 0.92
Localization of the active site of diphtheria toxin. Biochemistry (1988) 0.90
The site of attachment of retinal in bacteriorhodopsin. A resonance Raman study. J Biol Chem (1982) 0.88
Determination of the location of fluorescent probes attached to fatty acids using parallax analysis of fluorescence quenching: effect of carboxyl ionization state and environment on depth. Biochemistry (1992) 0.88
Major complications of minor surgery: a report of two cases of critical ischaemia unmasked by treatment for ingrown nails. J Bone Joint Surg Br (2005) 0.87
Effect of transducer placement on echocardiographic mitral valve motion. Am Heart J (1978) 0.87
Membrane topography of the T domain of diphtheria toxin probed with single tryptophan mutants. Biochemistry (1998) 0.86
Folding changes in membrane-inserted diphtheria toxin that may play important roles in its translocation. Biochemistry (1991) 0.85
Use of Trp mutations to evaluate the conformational behavior and membrane insertion of A and B chains in whole diphtheria toxin. Biochemistry (1997) 0.85
Two-dimensional echocardiographic analysis of segmental left ventricular wall motion before and after coronary artery bypass surgery. Circulation (1982) 0.84
Fluorescence characterization of the low pH-induced change in diphtheria toxin conformation: effect of salt. Biochem Biophys Res Commun (1984) 0.83
Evaluation of the echocardiogram as an epidemiologic tool in an asymptomatic population. Circulation (1979) 0.83
Simple procedure for reversed-phase high-performance liquid chromatographic purification of long hydrophobic peptides that form transmembrane helices. Anal Biochem (1997) 0.83
Cerebral metabolism in opiate-dependent subjects: effects of methadone maintenance. Mt Sinai J Med (2000) 0.83
Self-translocation of diphtheria toxin across model membranes. J Biol Chem (1991) 0.82
Investigation of membrane structure using fluorescence quenching by spin-labels. A review of recent studies. Mol Cell Biochem (1982) 0.82
Syndactylism with keloid scar formation. J Foot Ankle Surg (1994) 0.81
Pericardial effusions in patients with end-stage renal disease. Br Heart J (1978) 0.80
Effect of transducer placement on echocardiographic mitral valve systolic motion. Eur J Cardiol (1976) 0.80
Simple centrifugation method for efficient pelleting of both small and large unilamellar vesicles that allows convenient measurement of protein binding. Biochemistry (1993) 0.80
Subtalar distraction arthrodesis using a ramp cage. Orthopedics (2003) 0.79
Fluorescence quenching of Ca2+-ATPase in bilayer vesicles by a spin-labeled phospholipid. FEBS Lett (1978) 0.79
Interaction of diphtheria toxin with model membranes. Biochemistry (1988) 0.79
Method for efficient pelleting of small unilamellar model membrane vesicles. Anal Biochem (1994) 0.79
The effects of inhibitors upon pore formation by diphtheria toxin and diphtheria toxin T domain. J Membr Biol (1999) 0.78
Obliteration of a late traumatic posterior tibial artery pseudoaneurysm by duplex compression. J Trauma (2000) 0.78
Hsp85 conformational change within the heat shock temperature range. Biochem Biophys Res Commun (1992) 0.78
Immunochemical analysis shows all three domains of diphtheria toxin penetrate across model membranes. J Biol Chem (1995) 0.78
Novel pharmacologic approaches to the treatment of senile dementia of the Alzheimer's type (SDAT). Psychopharmacol Bull (1983) 0.78
Inadvertent concentrating of EDTA by ion exchange chromatography: avoiding artifacts that can interfere with protein purification. Anal Biochem (1997) 0.77
Periventricular lucencies in the CT scans of aged and demented patients. Biol Psychiatry (1986) 0.77
Immunochemical analysis of the structure of diphtheria toxin shows all three domains undergo structural changes at low pH. J Biol Chem (1995) 0.76
A comparison of the bioavailability of minocycline capsules and film-coated tablets. J Antimicrob Chemother (1975) 0.76
A fluorescence-based detergent binding assay for protein hydrophobicity. Anal Biochem (1986) 0.76
Technical complications of the tibiofibular syndesmotic screw. J Foot Ankle Surg (1994) 0.75
Hospital crisis. Consum Health Perspect (1981) 0.75
Complete duplication of an accessory first ray. J Foot Surg (1991) 0.75
Membrane-inserted colicin E1 channel domain: a topological survey by fluorescence quenching suggests that model membrane thickness affects membrane penetration. J Nat Toxins (1998) 0.75
One-stage treatment of gunshot wounds. J Foot Surg (1990) 0.75
The effect of high pH upon diphtheria toxin conformation and model membrane association: role of partial unfolding. Arch Biochem Biophys (1990) 0.75
Adrenal neuropeptide Y mRNA but not preproenkephalin mRNA induction by stress is impaired by aging in Fischer 344 rats. Mech Ageing Dev (1998) 0.75
Involvement of nigrotecto-reticulospinal pathways in the iminodipropionitrile (IDPN) model of spasmodic dyskinesias: a 2-deoxy-D-[1-14C]glucose study in the rat. Brain Res (1989) 0.75
Concomitant medial facet and dome fractures of the talus. J Foot Ankle Surg (1997) 0.75
GWAS meta-analysis reveals novel loci and genetic correlates for general cognitive function: a report from the COGENT consortium. Mol Psychiatry (2017) 0.75