Rank |
Title |
Journal |
Year |
PubWeight™‹?› |
1
|
Enhanced expression of transforming growth factor beta isoforms in pancreatic cancer correlates with decreased survival.
|
Gastroenterology
|
1993
|
2.86
|
2
|
The cell-surface heparan sulfate proteoglycan glypican-1 regulates growth factor action in pancreatic carcinoma cells and is overexpressed in human pancreatic cancer.
|
J Clin Invest
|
1998
|
2.22
|
3
|
Estrogen binding, receptor mRNA, and biologic response in osteoblast-like osteosarcoma cells.
|
Science
|
1988
|
2.22
|
4
|
Coexpression of epidermal growth factor receptor and ligands in human pancreatic cancer is associated with enhanced tumor aggressiveness.
|
Anticancer Res
|
1993
|
2.15
|
5
|
Overexpression of acidic and basic fibroblast growth factors in human pancreatic cancer correlates with advanced tumor stage.
|
Cancer Res
|
1993
|
2.08
|
6
|
Overexpression of HER2/neu oncogene in human pancreatic carcinoma.
|
Hum Pathol
|
1993
|
2.05
|
7
|
Insulin-like growth factor I overexpression in human pancreatic cancer: evidence for autocrine and paracrine roles.
|
Cancer Res
|
1995
|
1.89
|
8
|
Detection and localization of Mip-3alpha/LARC/Exodus, a macrophage proinflammatory chemokine, and its CCR6 receptor in human pancreatic cancer.
|
Int J Cancer
|
1999
|
1.81
|
9
|
Action of secretagogues on a new preparation of functionally intact, isolated pancreatic acini.
|
Am J Physiol
|
1978
|
1.80
|
10
|
Enhanced expression of vascular endothelial growth factor in human pancreatic cancer correlates with local disease progression.
|
Clin Cancer Res
|
1997
|
1.74
|
11
|
In vivo induction of massive proliferation, directed migration, and differentiation of neural cells in the adult mammalian brain.
|
Proc Natl Acad Sci U S A
|
2000
|
1.67
|
12
|
The TGF-beta signaling inhibitor Smad7 enhances tumorigenicity in pancreatic cancer.
|
Oncogene
|
1999
|
1.63
|
13
|
Microarray-based identification of differentially expressed growth- and metastasis-associated genes in pancreatic cancer.
|
Cell Mol Life Sci
|
2003
|
1.60
|
14
|
KAI1 expression is up-regulated in early pancreatic cancer and decreased in the presence of metastases.
|
Cancer Res
|
1996
|
1.59
|
15
|
Pancreatic islet-acinar cell interaction: amylase messenger RNA levels ar determined by insulin.
|
Science
|
1981
|
1.59
|
16
|
Glypican-1 is overexpressed in human breast cancer and modulates the mitogenic effects of multiple heparin-binding growth factors in breast cancer cells.
|
Cancer Res
|
2001
|
1.55
|
17
|
Enhanced expression of the type II transforming growth factor beta receptor in human pancreatic cancer cells without alteration of type III receptor expression.
|
Cancer Res
|
1993
|
1.53
|
18
|
Production of transforming growth factor alpha in human pancreatic cancer cells: evidence for a superagonist autocrine cycle.
|
Proc Natl Acad Sci U S A
|
1987
|
1.51
|
19
|
Enhanced expression of urokinase plasminogen activator and its receptor in pancreatic carcinoma.
|
Br J Cancer
|
1997
|
1.47
|
20
|
Enhanced glypican-3 expression differentiates the majority of hepatocellular carcinomas from benign hepatic disorders.
|
Gut
|
2001
|
1.46
|
21
|
Differential regulation of expression of three transforming growth factor beta species in human breast cancer cell lines by estradiol.
|
Cancer Res
|
1990
|
1.45
|
22
|
Enhanced expression of the type II transforming growth factor-beta receptor is associated with decreased survival in human pancreatic cancer.
|
Pancreas
|
1999
|
1.41
|
23
|
A variant epidermal growth factor receptor exhibits altered type alpha transforming growth factor binding and transmembrane signaling.
|
Proc Natl Acad Sci U S A
|
1994
|
1.41
|
24
|
Nerve growth factor expression correlates with perineural invasion and pain in human pancreatic cancer.
|
J Clin Oncol
|
1999
|
1.38
|
25
|
Syndecan-1 expression is up-regulated in pancreatic but not in other gastrointestinal cancers.
|
Int J Cancer
|
2000
|
1.37
|
26
|
Bone morphogenetic protein 2 exerts diverse effects on cell growth in vitro and is expressed in human pancreatic cancer in vivo.
|
Gastroenterology
|
1999
|
1.36
|
27
|
Aberrant expression of type I fibroblast growth factor receptor in human pancreatic adenocarcinomas.
|
Cancer Res
|
1993
|
1.36
|
28
|
Nerve growth factor and its high-affinity receptor in chronic pancreatitis.
|
Ann Surg
|
1999
|
1.35
|
29
|
Connective tissue growth factor is a regulator for fibrosis in human chronic pancreatitis.
|
Ann Surg
|
1999
|
1.34
|
30
|
Id-1 and Id-2 are overexpressed in pancreatic cancer and in dysplastic lesions in chronic pancreatitis.
|
Am J Pathol
|
1999
|
1.33
|
31
|
Enhanced expression of epidermal growth factor receptor correlates with alterations of chromosome 7 in human pancreatic cancer.
|
Proc Natl Acad Sci U S A
|
1986
|
1.33
|
32
|
Induction and expression of amphiregulin in human pancreatic cancer.
|
Cancer Res
|
1994
|
1.32
|
33
|
Increased expression of erbB3 in colorectal cancer is associated with concomitant increase in the level of erbB2.
|
Hum Pathol
|
1998
|
1.30
|
34
|
Concomitant over-expression of vascular endothelial growth factor and its receptors in pancreatic cancer.
|
Int J Cancer
|
2000
|
1.30
|
35
|
A KrasG12D-driven genetic mouse model of pancreatic cancer requires glypican-1 for efficient proliferation and angiogenesis.
|
Oncogene
|
2011
|
1.27
|
36
|
Transforming growth factor betas and their signaling receptors in human hepatocellular carcinoma.
|
Am J Surg
|
1999
|
1.27
|
37
|
Induction of platelet-derived growth factor A and B chains and over-expression of their receptors in human pancreatic cancer.
|
Int J Cancer
|
1995
|
1.26
|
38
|
Enhanced expression of the insulin receptor substrate-2 docking protein in human pancreatic cancer.
|
Cancer Res
|
1998
|
1.24
|
39
|
Coexpression of the c-met proto-oncogene and hepatocyte growth factor in human pancreatic cancer.
|
Cancer Res
|
1994
|
1.23
|
40
|
Pancreatic cancer cell-derived vascular endothelial growth factor is biologically active in vitro and enhances tumorigenicity in vivo.
|
Int J Cancer
|
2001
|
1.21
|
41
|
Enhanced erbB-3 expression in human pancreatic cancer correlates with tumor progression.
|
Clin Cancer Res
|
1995
|
1.19
|
42
|
Inhibition of basal and mitogen-stimulated pancreatic cancer cell growth by cyclin D1 antisense is associated with loss of tumorigenicity and potentiation of cytotoxicity to cisplatinum.
|
J Clin Invest
|
1998
|
1.19
|
43
|
Induction and expression of heparin-binding EGF-like growth factor in human pancreatic cancer.
|
Biochem Biophys Res Commun
|
1994
|
1.18
|
44
|
Increased expression of transforming growth factor beta isoforms and basic fibroblast growth factor in complex hyperplasia and adenocarcinoma of the endometrium: evidence for paracrine and autocrine action.
|
Cancer Res
|
1994
|
1.18
|
45
|
Pancreatic cancer: the potential clinical relevance of alterations in growth factors and their receptors.
|
J Mol Med (Berl)
|
1996
|
1.18
|
46
|
Soluble type II transforming growth factor-beta (TGF-beta) receptor inhibits TGF-beta signaling in COLO-357 pancreatic cancer cells in vitro and attenuates tumor formation.
|
Clin Cancer Res
|
2001
|
1.16
|
47
|
Transforming growth factor beta mediates the progesterone suppression of an epithelial metalloproteinase by adjacent stroma in the human endometrium.
|
Proc Natl Acad Sci U S A
|
1995
|
1.13
|
48
|
Increased expression of keratinocyte growth factor in human pancreatic cancer.
|
Biochem Biophys Res Commun
|
1995
|
1.13
|
49
|
bax, but not bcl-2, influences the prognosis of human pancreatic cancer.
|
Gut
|
1998
|
1.12
|
50
|
Synthesis and expression of transforming growth factor beta-1, beta-2, and beta-3 in the endocrine and exocrine pancreas.
|
Diabetes
|
1993
|
1.12
|
51
|
Actinomycin D induces apoptosis and inhibits growth of pancreatic cancer cells.
|
Int J Cancer
|
2000
|
1.12
|
52
|
Increased expression of insulin receptor substrate-1 in human pancreatic cancer.
|
Biochem Biophys Res Commun
|
1996
|
1.12
|
53
|
Cytosolic calcium regulates epidermal growth factor endocytosis in rat pancreas and cultured fibroblasts.
|
Proc Natl Acad Sci U S A
|
1984
|
1.10
|
54
|
Enhanced urokinase plasminogen activation in chronic pancreatitis suggests a role in its pathogenesis.
|
Gastroenterology
|
1997
|
1.09
|
55
|
p53 mutations are common in pancreatic cancer and are absent in chronic pancreatitis.
|
Cancer Lett
|
1993
|
1.09
|
56
|
Stable transfection of a glypican-1 antisense construct decreases tumorigenicity in PANC-1 pancreatic carcinoma cells.
|
Pancreas
|
1999
|
1.08
|
57
|
Neurotensin receptor-1 mRNA analysis in normal pancreas and pancreatic disease.
|
Clin Cancer Res
|
2000
|
1.08
|
58
|
Characterization of cytokeratin 20 expression in pancreatic and colorectal cancer.
|
Clin Cancer Res
|
1999
|
1.08
|
59
|
Fibroblast growth factor-5 stimulates mitogenic signaling and is overexpressed in human pancreatic cancer: evidence for autocrine and paracrine actions.
|
Oncogene
|
1997
|
1.08
|
60
|
Differential expression of metastasis-associated genes in papilla of vater and pancreatic cancer correlates with disease stage.
|
J Clin Oncol
|
2001
|
1.07
|
61
|
Increased expression of transforming growth factor beta s after acute oedematous pancreatitis in rats suggests a role in pancreatic repair.
|
Gut
|
1997
|
1.07
|
62
|
Increased expression of acidic and basic fibroblast growth factors in chronic pancreatitis.
|
Am J Pathol
|
1994
|
1.07
|
63
|
Inhibition of cyclin D1 expression in human pancreatic cancer cells is associated with increased chemosensitivity and decreased expression of multiple chemoresistance genes.
|
Cancer Res
|
1999
|
1.07
|
64
|
Characterization of keratinocyte growth factor and receptor expression in human pancreatic cancer.
|
Am J Pathol
|
1998
|
1.07
|
65
|
Epiregulin is Up-regulated in pancreatic cancer and stimulates pancreatic cancer cell growth.
|
Biochem Biophys Res Commun
|
2000
|
1.05
|
66
|
Overexpression of lymphangiogenic growth factor VEGF-C in human pancreatic cancer.
|
Pancreas
|
2001
|
1.05
|
67
|
Attenuated ALK5 receptor expression in human pancreatic cancer: correlation with resistance to growth inhibition.
|
Int J Cancer
|
1996
|
1.04
|
68
|
The helix-loop-helix protein Id2 is overexpressed in human pancreatic cancer.
|
Cancer Res
|
1998
|
1.04
|
69
|
Smad6 suppresses TGF-beta-induced growth inhibition in COLO-357 pancreatic cancer cells and is overexpressed in pancreatic cancer.
|
Biochem Biophys Res Commun
|
1999
|
1.03
|
70
|
Co-expression of heparin-binding EGF-like growth factor and related peptides in human gastric carcinoma.
|
Int J Cancer
|
1996
|
1.03
|
71
|
Overexpression of platelet-derived growth factor (PDGF) B chain and type beta PDGF receptor in human chronic pancreatitis.
|
Dig Dis Sci
|
1998
|
1.02
|
72
|
Galectin-1 and galectin-3 in chronic pancreatitis.
|
Lab Invest
|
2000
|
1.02
|
73
|
KAI1, a new metastasis suppressor gene, is reduced in metastatic hepatocellular carcinoma.
|
Hepatology
|
1998
|
1.01
|
74
|
Concomitant analysis of the epidermal growth factor receptor family in esophageal cancer: overexpression of epidermal growth factor receptor mRNA but not of c-erbB-2 and c-erbB-3.
|
World J Surg
|
1999
|
1.01
|
75
|
Reduced KAI1 expression in pancreatic cancer is associated with lymph node and distant metastases.
|
Int J Cancer
|
1998
|
1.01
|
76
|
Differential localization of transforming growth factor-beta isoforms in human gastric mucosa and overexpression in gastric carcinoma.
|
Int J Cancer
|
1997
|
1.00
|
77
|
Increased cyclin D1 in human pancreatic cancer is associated with decreased postoperative survival.
|
Oncology
|
1998
|
1.00
|
78
|
Growth inhibition of a human colorectal carcinoma cell line by interleukin 1 is associated with enhanced expression of gamma-interferon receptors.
|
Cancer Res
|
1993
|
1.00
|
79
|
Molecular aspects of pancreatic cancer and future perspectives.
|
Dig Surg
|
1999
|
1.00
|
80
|
Transforming growth factor-betas and their signaling receptors are coexpressed in Crohn's disease.
|
Ann Surg
|
1999
|
0.99
|
81
|
Enhanced expression of TGF-betas and their receptors in human acute pancreatitis.
|
Ann Surg
|
1998
|
0.97
|
82
|
Insulin receptors in isolated mouse pancreatic acini.
|
Biochem Biophys Res Commun
|
1978
|
0.97
|
83
|
KAI1 is unchanged in metastatic and nonmetastatic esophageal and gastric cancers.
|
Cancer Res
|
1998
|
0.96
|
84
|
Effects of enterally fed epidermal growth factor on the small and large intestine of the suckling rat.
|
Regul Pept
|
1987
|
0.96
|
85
|
Growth factor receptors are differentially expressed in cancers of the papilla of vater and pancreas.
|
Ann Surg
|
1999
|
0.96
|
86
|
Expression of a truncated EGF receptor is associated with inhibition of pancreatic cancer cell growth and enhanced sensitivity to cisplatinum.
|
Int J Cancer
|
1996
|
0.96
|
87
|
Role of fibroblast growth factors and their receptors in pancreatic cancer and chronic pancreatitis.
|
Pancreas
|
1998
|
0.96
|
88
|
AGR2 is a SMAD4-suppressible gene that modulates MUC1 levels and promotes the initiation and progression of pancreatic intraepithelial neoplasia.
|
Oncogene
|
2012
|
0.95
|
89
|
p53 expression in human pancreatic cancer correlates with enhanced biological aggressiveness.
|
Anticancer Res
|
1995
|
0.95
|
90
|
Binding of epidermal growth factor in rat pancreatic acini.
|
Biochem Biophys Res Commun
|
1983
|
0.95
|
91
|
Nerve growth factor exerts differential effects on the growth of human pancreatic cancer cells.
|
Clin Cancer Res
|
2001
|
0.95
|
92
|
Transfection of the type I TGF-beta receptor restores TGF-beta responsiveness in pancreatic cancer.
|
Int J Cancer
|
1998
|
0.94
|
93
|
Divergent effects of epidermal growth factor and transforming growth factors on a human endometrial carcinoma cell line.
|
Cancer Res
|
1987
|
0.94
|
94
|
Bcl-x(L) antisense oligonucleotides induce apoptosis and increase sensitivity of pancreatic cancer cells to gemcitabine.
|
Int J Cancer
|
2001
|
0.94
|
95
|
Altered expression of transforming growth factor-beta ligands and receptors in primary and recurrent ovarian carcinoma.
|
Cancer
|
1999
|
0.94
|
96
|
Cripto, a member of the epidermal growth factor family, is over-expressed in human pancreatic cancer and chronic pancreatitis.
|
Int J Cancer
|
1994
|
0.94
|
97
|
Growth inhibition of human pancreatic carcinoma cells by transforming growth factor beta-1.
|
Growth Factors
|
1993
|
0.93
|
98
|
Up-regulation of transforming growth factor (TGF)-beta receptors by TGF-beta1 in COLO-357 cells.
|
J Biol Chem
|
1998
|
0.93
|
99
|
Expression of metallothionein II in intestinal metaplasia, dysplasia, and gastric cancer.
|
Cancer Res
|
2000
|
0.93
|
100
|
Binding and biological effects of tumor necrosis factor and gamma interferon in human pancreatic carcinoma cells.
|
Pancreas
|
1990
|
0.93
|
101
|
Pancreatic cancer cells express interleukin-13 and -4 receptors, and their growth is inhibited by Pseudomonas exotoxin coupled to interleukin-13 and -4.
|
Anticancer Res
|
1999
|
0.92
|
102
|
Coexpression of FAS and FAS-ligand in chronic pancreatitis: correlation with apoptosis.
|
Pancreas
|
2000
|
0.92
|
103
|
Regulation of transforming growth factor-alpha mRNA expression in T3M4 human pancreatic carcinoma cells.
|
Pancreas
|
1991
|
0.92
|
104
|
Alteration of fibroblast growth factor and receptor expression after acute pancreatitis in humans.
|
Pancreas
|
1999
|
0.91
|
105
|
Effects of dietary manganese deficiency on rat pancreatic amylase mRNA levels.
|
J Nutr
|
1990
|
0.91
|
106
|
A cholinergic antagonist identifies a subclass of muscarinic receptors in isolated rat pancreatic acini.
|
J Pharmacol Exp Ther
|
1987
|
0.91
|
107
|
Ligand induced upregulation of the type II transforming growth factor (TGF-beta) receptor enhances TGF-beta responsiveness in COLO-357 cells.
|
Pancreas
|
1999
|
0.90
|
108
|
Overexpression of activin A in stage IV colorectal cancer.
|
Gut
|
2001
|
0.90
|
109
|
Altered expression and localization of the tight junction protein ZO-1 in primary and metastatic pancreatic cancer.
|
Pancreas
|
2001
|
0.89
|
110
|
Insulin action in pancreatic acini from streptozotocin-treated rats. II. Binding of 125I-insulin to receptors.
|
Am J Physiol
|
1981
|
0.89
|
111
|
Insulin-like growth factor I improves cardiovascular function and suppresses apoptosis of cardiomyocytes in dilated cardiomyopathy.
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Endocrinology
|
1999
|
0.89
|
112
|
A subgroup of patients with chronic pancreatitis overexpress the c-erb B-2 protooncogene.
|
Ann Surg
|
1994
|
0.89
|
113
|
Presence of two signaling TGF-beta receptors in human pancreatic cancer correlates with advanced tumor stage.
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Dig Dis Sci
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1997
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0.88
|
114
|
Suppression of fibroblast growth factor receptor signaling inhibits pancreatic cancer growth in vitro and in vivo.
|
Gastroenterology
|
1998
|
0.88
|
115
|
Fas and Fas-ligand expression in human pancreatic cancer.
|
Ann Surg
|
2000
|
0.88
|
116
|
Expression of the multidrug-resistance 1 (MDR1) gene and prognosis in human pancreatic cancer.
|
Pancreas
|
2000
|
0.88
|
117
|
Cloning of a variant epidermal growth factor receptor.
|
Biochem Biophys Res Commun
|
1993
|
0.88
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118
|
Tumor necrosis factor up-regulates gamma-interferon binding in a human carcinoma cell line.
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J Biol Chem
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1990
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0.88
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119
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Neoadjuvant cetuximab, twice-weekly gemcitabine, and intensity-modulated radiotherapy (IMRT) in patients with pancreatic adenocarcinoma.
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Ann Oncol
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2012
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0.88
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120
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Recycling of epidermal growth factor in a human pancreatic carcinoma cell line.
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Proc Natl Acad Sci U S A
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1985
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0.88
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121
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Concomitant over-expression of activin/inhibin beta subunits and their receptors in human pancreatic cancer.
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Int J Cancer
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1998
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0.88
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122
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Regulation of protein synthesis in normal and diabetic rat pancreas by cholecystokinin.
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Am J Physiol
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1981
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0.87
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123
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Amphiregulin antisense oligonucleotide inhibits the growth of T3M4 human pancreatic cancer cells and sensitizes the cells to EGF receptor-targeted therapy.
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Int J Cancer
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1997
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0.87
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124
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Manganese action on pancreatic protein synthesis in normal and diabetic rats.
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Am J Physiol
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1983
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0.87
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125
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Altered expression of insulin-like growth factor II receptor in human pancreatic cancer.
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Pancreas
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1997
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0.87
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126
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Differential regulation of fibroblast growth factor (FGF) receptor-1 mRNA and protein by two molecular forms of basic FGF. Modulation of FGFR-1 mRNA stability.
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J Biol Chem
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1996
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0.87
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127
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ErbB-4 mRNA expression is decreased in non-metastatic pancreatic cancer.
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Int J Cancer
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1999
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0.86
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128
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Altered expression of transforming growth factor-beta S in chronic renal rejection.
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Kidney Int
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1996
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0.85
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129
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TGF-beta-1 up-regulates cyclin D1 expression in COLO-357 cells, whereas suppression of cyclin D1 levels is associated with down-regulation of the type I TGF-beta receptor.
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Int J Cancer
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1999
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0.84
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130
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Absence of K-ras mutations in the pancreatic parenchyma of patients with chronic pancreatitis.
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Am J Surg
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1997
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0.83
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131
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Residual inhibition of epidermal growth factor binding by pancreatic secretagogues and phorbol ester in rat pancreas.
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J Cell Physiol
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1985
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0.83
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132
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Epidermal growth factor inhibits the proliferation of a human endometrial carcinoma cell line.
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J Clin Endocrinol Metab
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1986
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0.83
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133
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Stimulation of the glucose transport system in isolated mouse pancreatic acini by cholecystokinin and analogues.
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J Biol Chem
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1979
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0.83
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134
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Intratumoral delivery of shRNA targeting cyclin D1 attenuates pancreatic cancer growth.
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Cancer Gene Ther
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2009
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0.83
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135
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Epidermal growth factor receptor overexpression and trisomy 7 in a case of Barrett's esophagus.
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Dig Dis Sci
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1990
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0.83
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136
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Epidermal growth factor inhibits rat pancreatic cell proliferation, causes acinar cell hypertrophy, and prevents caerulein-induced desensitization of amylase release.
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Endocrinology
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1989
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0.82
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137
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Regulation of pancreatic protein synthesis by cholecystokinin and calcium.
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Am J Physiol
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1982
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0.82
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138
|
Expression of the high molecular weight fibroblast growth factor-2 isoform of 210 amino acids is associated with modulation of protein kinases C delta and epsilon and ERK activation.
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J Biol Chem
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2001
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0.82
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139
|
Upregulation of interferon-gamma binding by tumor necrosis factor and lymphotoxin: disparate potencies of the cytokines and modulation of their effects by phorbol ester.
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J Interferon Res
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1991
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0.82
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140
|
The plasminogen activator/plasmin system is up-regulated after acute necrotizing pancreatitis in human beings.
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Surgery
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1998
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0.82
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141
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Receptors for cholecystokinin and insulin in isolated pancreatic acini: hormonal control of secretion and metabolism.
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Fed Proc
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1981
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0.82
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142
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Transforming growth factor betas and their receptors in human liver cirrhosis.
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Eur J Gastroenterol Hepatol
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1998
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0.82
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143
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Bak expression and cell death occur in peritumorous tissue but not in pancreatic cancer cells.
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J Gastrointest Surg
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2000
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0.81
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144
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Expression of the IIIc variant of FGF receptor-1 confers mitogenic responsiveness to heparin and FGF-5 in TAKA-1 pancreatic ductal cells.
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Int J Pancreatol
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2001
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0.81
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145
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Increased mdm2 expression and immunoreactivity in human pancreatic ductal adenocarcinoma.
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Int J Oncol
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1994
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0.80
|
146
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Increased cyclin D1 expression in chronic pancreatitis.
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Pancreas
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1998
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0.80
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147
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Effects of 1-oleoyl-2-acetyl glycerol are distinct from those of phorbol ester in rat pancreatic acini.
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Life Sci
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1987
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0.80
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148
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Direct modulation of epidermal growth factor binding by cholecystokinin.
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Life Sci
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1983
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0.80
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149
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Effects of epidermal growth factor, insulin and insulin-like growth factor I on rat pancreatic acinar cells cultured in serum-free medium.
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Pancreas
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1988
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0.79
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150
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Differential distribution of human epidermal growth factor receptor family in acute pancreatitis.
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Dig Dis Sci
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