Rank |
Title |
Journal |
Year |
PubWeight™‹?› |
1
|
Mutations in a member of the ADAMTS gene family cause thrombotic thrombocytopenic purpura.
|
Nature
|
2001
|
6.95
|
2
|
Genome-wide search for genes affecting the risk for alcohol dependence.
|
Am J Med Genet
|
1998
|
6.04
|
3
|
Localization of an ataxia-telangiectasia gene to chromosome 11q22-23.
|
Nature
|
1988
|
3.82
|
4
|
Genome-wide association study of bipolar disorder in European American and African American individuals.
|
Mol Psychiatry
|
2009
|
3.64
|
5
|
An autosomal genomic scan for loci linked to type II diabetes mellitus and body-mass index in Pima Indians.
|
Am J Hum Genet
|
1998
|
3.16
|
6
|
A genome screen of maximum number of drinks as an alcoholism phenotype.
|
Am J Med Genet
|
2000
|
3.14
|
7
|
LRRK2 mutation analysis in Parkinson disease families with evidence of linkage to PARK8.
|
Neurology
|
2007
|
2.86
|
8
|
Mutations in GBA are associated with familial Parkinson disease susceptibility and age at onset.
|
Neurology
|
2008
|
2.73
|
9
|
Singleton deletions throughout the genome increase risk of bipolar disorder.
|
Mol Psychiatry
|
2008
|
2.50
|
10
|
Joint multipoint linkage analysis of multivariate qualitative and quantitative traits. II. Alcoholism and event-related potentials.
|
Am J Hum Genet
|
1999
|
2.23
|
11
|
An autosomal genomic scan for loci linked to prediabetic phenotypes in Pima Indians.
|
J Clin Invest
|
1998
|
2.18
|
12
|
ADH1B is associated with alcohol dependence and alcohol consumption in populations of European and African ancestry.
|
Mol Psychiatry
|
2011
|
2.05
|
13
|
Saccades in presymptomatic and early stages of Huntington disease.
|
Neurology
|
2006
|
1.92
|
14
|
Enrichment of cis-regulatory gene expression SNPs and methylation quantitative trait loci among bipolar disorder susceptibility variants.
|
Mol Psychiatry
|
2012
|
1.84
|
15
|
Autosomal genomic scan for loci linked to obesity and energy metabolism in Pima Indians.
|
Am J Hum Genet
|
1998
|
1.78
|
16
|
A genome-wide search for genes that relate to a low level of response to alcohol.
|
Alcohol Clin Exp Res
|
2001
|
1.72
|
17
|
Linkage of the Indiana kindred of Gerstmann-Sträussler-Scheinker disease to the prion protein gene.
|
Nat Genet
|
1992
|
1.66
|
18
|
Genome-wide association study of CSF biomarkers Abeta1-42, t-tau, and p-tau181p in the ADNI cohort.
|
Neurology
|
2010
|
1.63
|
19
|
Linkage of structure at the proximal femur to chromosomes 3, 7, 8, and 19.
|
J Bone Miner Res
|
2003
|
1.55
|
20
|
Localization of the gene for familial primary pulmonary hypertension to chromosome 2q31-32.
|
Nat Genet
|
1997
|
1.52
|
21
|
Variation in GIGYF2 is not associated with Parkinson disease.
|
Neurology
|
2009
|
1.47
|
22
|
Evidence for a locus on chromosome 1 that influences vulnerability to alcoholism and affective disorder.
|
Am J Psychiatry
|
2001
|
1.46
|
23
|
Sibling pair linkage and association studies between bone mineral density and the insulin-like growth factor I gene locus.
|
J Clin Endocrinol Metab
|
1999
|
1.45
|
24
|
Genome screen for QTLs contributing to normal variation in bone mineral density and osteoporosis.
|
J Clin Endocrinol Metab
|
2000
|
1.43
|
25
|
Quantitative trait loci analysis of human event-related brain potentials: P3 voltage.
|
Electroencephalogr Clin Neurophysiol
|
1998
|
1.43
|
26
|
Association of the kappa-opioid system with alcohol dependence.
|
Mol Psychiatry
|
2006
|
1.42
|
27
|
Longitudinal cognitive and motor changes among presymptomatic Huntington disease gene carriers.
|
Arch Neurol
|
1999
|
1.41
|
28
|
Lrrk2 R1441C parkinsonism is clinically similar to sporadic Parkinson disease.
|
Neurology
|
2008
|
1.39
|
29
|
A quantitative trait locus for alcohol consumption in selectively bred rat lines.
|
Alcohol Clin Exp Res
|
1998
|
1.37
|
30
|
Initial genome scan of the NIMH genetics initiative bipolar pedigrees: chromosomes 4, 7, 9, 18, 19, 20, and 21q.
|
Am J Med Genet
|
1997
|
1.36
|
31
|
Genomic screen for QTLs underlying alcohol consumption in the P and NP rat lines.
|
Mamm Genome
|
1998
|
1.35
|
32
|
Subtle changes among presymptomatic carriers of the Huntington's disease gene.
|
J Neurol Neurosurg Psychiatry
|
2000
|
1.32
|
33
|
Initial genomic scan of the NIMH genetics initiative bipolar pedigrees: chromosomes 3, 5, 15, 16, 17, and 22.
|
Am J Med Genet
|
1997
|
1.30
|
34
|
Whole-exome sequencing and imaging genetics identify functional variants for rate of change in hippocampal volume in mild cognitive impairment.
|
Mol Psychiatry
|
2013
|
1.30
|
35
|
Progression of symptoms in the early and middle stages of Huntington disease.
|
Arch Neurol
|
2001
|
1.30
|
36
|
A primary linkage map of the human chromosome 11q22-23 region.
|
Genomics
|
1990
|
1.25
|
37
|
Amplitude of visual P3 event-related potential as a phenotypic marker for a predisposition to alcoholism: preliminary results from the COGA Project. Collaborative Study on the Genetics of Alcoholism.
|
Alcohol Clin Exp Res
|
1998
|
1.22
|
38
|
A genome-wide association study of alcohol-dependence symptom counts in extended pedigrees identifies C15orf53.
|
Mol Psychiatry
|
2012
|
1.21
|
39
|
Prenatal alcohol exposure alters the patterns of facial asymmetry.
|
Alcohol
|
2010
|
1.21
|
40
|
Confirmation of subtle motor changes among presymptomatic carriers of the Huntington disease gene.
|
Arch Neurol
|
2000
|
1.19
|
41
|
Linkage of a QTL contributing to normal variation in bone mineral density to chromosome 11q12-13.
|
J Bone Miner Res
|
1998
|
1.18
|
42
|
Genomewide search for genes influencing percent body fat in Pima Indians: suggestive linkage at chromosome 11q21-q22. Pima Diabetes Gene Group.
|
Am J Hum Genet
|
1997
|
1.17
|
43
|
Genome screen for quantitative trait loci underlying normal variation in femoral structure.
|
J Bone Miner Res
|
2001
|
1.16
|
44
|
Initial genome screen for bipolar disorder in the NIMH genetics initiative pedigrees: chromosomes 2, 11, 13, 14, and X.
|
Am J Med Genet
|
1997
|
1.15
|
45
|
Motor changes in presymptomatic Huntington disease gene carriers.
|
Arch Neurol
|
1996
|
1.14
|
46
|
Identification of a quantitative trait locus on rat chromosome 4 that is strongly linked to femoral neck structure and strength.
|
Bone
|
2006
|
1.12
|
47
|
The ATC (ataxia-telangiectasia complementation group C) locus localizes to 11q22-q23.
|
Genomics
|
1991
|
1.11
|
48
|
Anxiety proneness linked to epistatic loci in genome scan of human personality traits.
|
Am J Med Genet
|
1998
|
1.11
|
49
|
Genetics of event-related brain potentials in response to a semantic priming paradigm in families with a history of alcoholism.
|
Am J Hum Genet
|
2000
|
1.11
|
50
|
Initial genome scan of the NIMH genetics initiative bipolar pedigrees: chromosomes 1, 6, 8, 10, and 12.
|
Am J Med Genet
|
1997
|
1.10
|
51
|
Further mapping of an ataxia-telangiectasia locus to the chromosome 11q23 region.
|
Am J Hum Genet
|
1990
|
1.10
|
52
|
Parkin dosage mutations have greater pathogenicity in familial PD than simple sequence mutations.
|
Neurology
|
2009
|
1.10
|
53
|
Linkage stratification and mutation analysis at the Parkin locus identifies mutation positive Parkinson's disease families.
|
J Med Genet
|
2002
|
1.09
|
54
|
Variability in skeletal mass, structure, and biomechanical properties among inbred strains of rats.
|
J Bone Miner Res
|
2001
|
1.09
|
55
|
A genome-wide screen for genes influencing conduct disorder.
|
Mol Psychiatry
|
2004
|
1.07
|
56
|
Automated diagnosis of fetal alcohol syndrome using 3D facial image analysis.
|
Orthod Craniofac Res
|
2008
|
1.04
|
57
|
Genes influencing Parkinson disease onset: replication of PARK3 and identification of novel loci.
|
Neurology
|
2004
|
1.01
|
58
|
Genotype patterns at PICALM, CR1, BIN1, CLU, and APOE genes are associated with episodic memory.
|
Neurology
|
2012
|
0.99
|
59
|
Familial multiple-system tauopathy with presenile dementia is localized to chromosome 17.
|
Am J Hum Genet
|
1997
|
0.99
|
60
|
Family-based study of the association of the dopamine D2 receptor gene (DRD2) with habitual smoking.
|
Am J Med Genet
|
2000
|
0.98
|
61
|
Family-based genome-wide association study of frontal θ oscillations identifies potassium channel gene KCNJ6.
|
Genes Brain Behav
|
2012
|
0.98
|
62
|
Possible localization of a major gene for cleft lip and palate to 4q.
|
Clin Genet
|
1994
|
0.98
|
63
|
Functional relevance of human adh polymorphism.
|
Alcohol Clin Exp Res
|
2001
|
0.95
|
64
|
Genome-wide linkage analysis of 972 bipolar pedigrees using single-nucleotide polymorphisms.
|
Mol Psychiatry
|
2011
|
0.93
|
65
|
Chromosome 6 workshop report.
|
Am J Med Genet
|
1999
|
0.92
|
66
|
A sex-adjusted and age-adjusted genome screen for nested alcohol dependence diagnoses.
|
Psychiatr Genet
|
2005
|
0.92
|
67
|
A family-based analysis of the association of the dopamine D2 receptor (DRD2) with alcoholism.
|
Alcohol Clin Exp Res
|
1998
|
0.90
|
68
|
A family-based analysis of whether the functional promoter alleles of the serotonin transporter gene HTT affect the risk for alcohol dependence.
|
Alcohol Clin Exp Res
|
1998
|
0.89
|
69
|
Confirmation of linkage of limb-girdle muscular dystrophy, type 2, to chromosome 15.
|
Genomics
|
1992
|
0.88
|
70
|
Independent and epistatic effects of variants in VPS10-d receptors on Alzheimer disease risk and processing of the amyloid precursor protein (APP).
|
Transl Psychiatry
|
2013
|
0.88
|
71
|
Genetics of bipolar affective disorder.
|
Curr Psychiatry Rep
|
2000
|
0.86
|
72
|
Heterogeneity in hereditary pancreatitis.
|
Am J Med Genet
|
1998
|
0.84
|
73
|
Stoppage: an issue for segregation analysis.
|
Genet Epidemiol
|
2001
|
0.83
|
74
|
The North American Multiple System Atrophy Study Group.
|
J Neural Transm (Vienna)
|
2005
|
0.81
|
75
|
Update on chromosomal locations for psychiatric disorders: report of the interim meeting of chromosome workshop chairpersons from the VIIth World Congress of Psychiatric Genetics, Monterey, California, October 14-18, 1999.
|
Am J Med Genet
|
2000
|
0.81
|
76
|
Common biological networks underlie genetic risk for alcoholism in African- and European-American populations.
|
Genes Brain Behav
|
2013
|
0.81
|
77
|
Use of variable marker density, principal components, and neural networks in the dissection of disease etiology.
|
Genet Epidemiol
|
2001
|
0.80
|
78
|
Identification of functional variants from whole-exome sequencing, combined with neuroimaging genetics.
|
Mol Psychiatry
|
2013
|
0.80
|
79
|
Spheroid body myopathy revisited.
|
Muscle Nerve
|
1997
|
0.79
|
80
|
Locus heterogeneity of autosomal dominant osteopetrosis (ADO).
|
J Clin Endocrinol Metab
|
1999
|
0.79
|
81
|
Age at intracranial aneurysm rupture among generations: Familial Intracranial Aneurysm Study.
|
Neurology
|
2009
|
0.76
|
82
|
Genome screen for platelet monoamine oxidase (MAO) activity.
|
Am J Med Genet
|
1999
|
0.76
|
83
|
Chromosome 6 workshop.
|
Psychiatr Genet
|
1998
|
0.75
|
84
|
Parametric linkage analysis and disequilibrium methods to identify loci for complex disease.
|
Genet Epidemiol
|
2001
|
0.75
|
85
|
Linkage of type II and type III cystinuria to 19q13.1: codominant inheritance of two cystinuric alleles at 19q13.1 produces an extreme stone-forming phenotype.
|
Am J Med Genet
|
1999
|
0.75
|
86
|
Sib pair linkage and association studies between bone mineral density and the interleukin-6 gene locus.
|
Bone
|
2000
|
0.75
|
87
|
Nonparametric linkage and family-based association studies of a simulated complex disorder.
|
Genet Epidemiol
|
1999
|
0.75
|
88
|
Gene mapping using linkage analysis.
|
Turk J Pediatr
|
1993
|
0.75
|