PubRank

S Humphries

Author PubWeight™ 97.01‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 The effect of novel polymorphisms in the interleukin-6 (IL-6) gene on IL-6 transcription and plasma IL-6 levels, and an association with systemic-onset juvenile chronic arthritis. J Clin Invest 1998 6.76
2 A cladistic analysis of phenotype associations with haplotypes inferred from restriction endonuclease mapping. II. The analysis of natural populations. Genetics 1988 2.68
3 Localization of stromelysin gene expression in atherosclerotic plaques by in situ hybridization. Proc Natl Acad Sci U S A 1991 2.53
4 Angiotensin-converting-enzyme gene insertion/deletion polymorphism and response to physical training. Lancet 1999 2.27
5 The two allele sequences of a common polymorphism in the promoter of the plasminogen activator inhibitor-1 (PAI-1) gene respond differently to interleukin-1 in HepG2 cells. J Biol Chem 1993 1.94
6 Kinetic studies of gene frequency. I. Use of a DNA copy of reticulocyte 9 S RNA to estimate globin gene dosage in mouse tissues. J Mol Biol 1974 1.87
7 Kinetic studies of gene frequency. II. Complexity of globin complementary DNA and its hybridization characteristics. J Mol Biol 1974 1.78
8 Mouse globin gene expression in erythroid and non-erythroid tissues. Cell 1976 1.75
9 Translation of mouse globin messenger ribonucleic acid from which the poly(adenylic acid) sequence has been removed. Biochemistry 1974 1.72
10 Bradykinin B2BKR receptor polymorphism and left-ventricular growth response. Lancet 2001 1.67
11 Human angiotensin I-converting enzyme gene and endurance performance. J Appl Physiol (1985) 1999 1.61
12 Allele specific amplification by tetra-primer PCR. Nucleic Acids Res 1992 1.56
13 Association of angiotensin-converting enzyme gene I/D polymorphism with change in left ventricular mass in response to physical training. Circulation 1997 1.48
14 The effects of norethisterone on endometrial abnormalities identified by transvaginal ultrasound screening of healthy post-menopausal women on tamoxifen or placebo. Br J Cancer 1998 1.44
15 Capsid protein precursor is one of two initiated products of translation of poliovirus RNA in vitro. J Virol 1979 1.37
16 Unequal crossing-over between two alu-repetitive DNA sequences in the low-density-lipoprotein-receptor gene. A possible mechanism for the defect in a patient with familial hypercholesterolaemia. Eur J Biochem 1987 1.34
17 Dynamics of alpha-tubulin deacetylation in intact neurons. J Neurosci 1989 1.32
18 Genetic variation at the plasminogen activator inhibitor-1 locus is associated with altered levels of plasma plasminogen activator inhibitor-1 activity. Arterioscler Thromb 1991 1.30
19 Cholesteryl ester transfer protein gene effect on CETP activity and plasma high-density lipoprotein in European populations. The EARS Group. Eur J Clin Invest 1999 1.24
20 Elite swimmers and the D allele of the ACE I/D polymorphism. Hum Genet 2001 1.18
21 Rapid screening for specific mutations in patients with a clinical diagnosis of familial hypercholesterolaemia. Atherosclerosis 1991 1.14
22 Identification of deletions in the human low density lipoprotein receptor gene. J Med Genet 1987 1.08
23 Familial defective apolipoprotein B-100. Comparison with familial hypercholesterolemia in 18 cases detected in Munich. Arteriosclerosis 1990 1.08
24 G to A substitution in the promoter region of the apolipoprotein AI gene is associated with elevated serum apolipoprotein AI and high density lipoprotein cholesterol concentrations. Mol Biol Med 1990 1.06
25 Characterization of deletions in the LDL receptor gene in patients with familial hypercholesterolemia in the United Kingdom. Arterioscler Thromb 1992 1.05
26 Reproductive biology. Out with a bang. Nature 2001 1.03
27 Variation in the size of human apolipoprotein(a) is due to a hypervariable region in the gene. Hum Genet 1990 1.02
28 Genetic evidence from two families that the apolipoprotein B gene is not involved in abetalipoproteinemia. J Clin Invest 1988 1.02
29 The globin gene: structure and expression. Cold Spring Harb Symp Quant Biol 1974 1.01
30 C677T (thermolabile alanine/valine) polymorphism in methylenetetrahydrofolate reductase (MTHFR): its frequency and impact on plasma homocysteine concentration in different European populations. EARS group. Atherosclerosis 1998 0.99
31 The gene for the Lp(a)-specific glycoprotein is closely linked to the gene for plasminogen on chromosome 6. Hum Genet 1989 0.97
32 The acute rise in plasma fibrinogen concentration with exercise is influenced by the G-453-A polymorphism of the beta-fibrinogen gene. Arterioscler Thromb Vasc Biol 1996 0.96
33 Computer modeling of the effect of perfusion on heating patterns in radiofrequency tumor ablation. Int J Hyperthermia 2007 0.96
34 Use of the single-strand conformational polymorphism method to detect recurrent and novel mutations in the low-density lipoprotein receptor gene in patients with familial hypercholesterolaemia: detection of a novel mutation Asp200-->Gly. Clin Investig 1993 0.94
35 The isolation of cloned cDNA sequences which are differentially expressed in human lymphocytes and fibroblasts. Nucleic Acids Res 1980 0.94
36 Bayesian methods for meta-analysis of causal relationships estimated using genetic instrumental variables. Stat Med 2010 0.93
37 Antibody repertoires of four- and five-feature translocus mice carrying human immunoglobulin heavy chain and kappa and lambda light chain yeast artificial chromosomes. J Immunol 1999 0.92
38 Association between genetic variation at the APO AI-CIII-AIV gene cluster and familial combined hyperlipidaemia. Clin Genet 1994 0.91
39 The role of beta-fibrinogen genotype in determining plasma fibrinogen levels in young survivors of myocardial infarction and healthy controls from Sweden. Thromb Haemost 1993 0.89
40 Role of genetic variation at the apo AI-CIII-AIV gene cluster in determining plasma apo AI levels in boys and girls. Genet Epidemiol 1993 0.89
41 The angiotensin-converting enzyme gene and the angiotensin II type I receptor gene as candidate genes for microalbuminuria. A study in nondiabetic and non-insulin-dependent diabetic subjects. Arterioscler Thromb Vasc Biol 1997 0.89
42 Polymorphisms in the 5'-flanking region of the insulin gene and non-insulin-dependent diabetes. Clin Sci (Lond) 1984 0.88
43 Linkage disequilibrium across the fibrinogen locus as shown by five genetic polymorphisms, G/A-455 (HaeIII), C/T-148 (HindIII/AluI), T/G+1689 (AvaII), and BclI (beta-fibrinogen) and TaqI (alpha-fibrinogen), and their detection by PCR. Hum Mutat 1994 0.88
44 Identification of the 664 proline to leucine mutation in the low density lipoprotein receptor in four unrelated patients with familial hypercholesterolaemia in the UK. Clin Genet 1991 0.88
45 RF tumour ablation: computer simulation and mathematical modelling of the effects of electrical and thermal conductivity. Int J Hyperthermia 2005 0.88
46 A radiographic investigation into bone resorption of mandibular alveolar bone in elderly edentulous adults. J Dent 1989 0.88
47 Apolipoprotein E genotyping in Alzheimer's disease. Lancet 1996 0.88
48 Survey of the allelic frequency of a NOS2A promoter microsatellite in human populations: assessment of the NOS2A gene and predisposition to infectious disease. Nitric Oxide 2000 0.88
49 Apolipoprotein B signal peptide insertion/deletion polymorphism is associated with Ag epitopes and involved in the determination of serum triglyceride levels. J Lipid Res 1990 0.87
50 A common genetic polymorphism associated with lower coagulation factor VII levels in healthy individuals. Arterioscler Thromb 1991 0.84
51 The isolation of cDNA clones for human apolipoprotein E and the detection of apoE RNA in hepatic and extra-hepatic tissues. EMBO J 1983 0.84
52 The influence of surface energy on the self-cleaning of insect adhesive devices. J Exp Biol 2012 0.84
53 Effect of the StuI polymorphism in the LDL receptor gene (Ala 370 to Thr) on lipid levels in healthy individuals. Clin Genet 1995 0.83
54 The molecular basis of truncated forms of apolipoprotein B in a kindred with compound heterozygous hypobetalipoproteinemia. J Lipid Res 1989 0.83
55 Genetic evidence that the putative receptor binding domain of apolipoprotein B (residues 3130 to 3630) is not the only region of the protein involved in interaction with the low density lipoprotein receptor. Biochim Biophys Acta 1991 0.83
56 Genetic and environmental determinants of factor VII coagulant activity in ethnic groups at differing risk of coronary heart disease. Atherosclerosis 1992 0.82
57 Apolipoprotein B gene polymorphisms, lipoproteins and coronary atherosclerosis: a study of young myocardial infarction survivors and healthy population-based individuals. Atherosclerosis 1992 0.81
58 Allelic variation adjacent to the human insulin and apolipoprotein C-II genes in different ethnic groups. Hum Genet 1985 0.81
59 Factor VII Arg/Gln353 polymorphism determines factor VII coagulant activity in patients with myocardial infarction (MI) and control subjects in Belfast and in France but is not a strong indicator of MI risk in the ECTIM study. Atherosclerosis 1996 0.81
60 I705 variant in the low denisty lipoprotein receptor gene has no effect on plasma cholesterol levels. J Med Genet 2000 0.81
61 Matrix metalloproteinases: implication in vascular matrix remodelling during atherogenesis. Clin Sci (Lond) 1998 0.81
62 XbaI polymorphism of the apolipoprotein B gene influences plasma lipid response to diet intervention. Clin Genet 1990 0.81
63 Four DNA polymorphisms in the LDL-receptor gene and their use in diagnosis of familial hypercholesterolemia. Hum Genet 1989 0.81
64 Isolation and characterisation of cDNA clones for the A alpha- and gamma-chains of human fibrinogen. Nucleic Acids Res 1983 0.80
65 Radiographic evaluation of surgical clips is better than ultrasound for defining the lumpectomy cavity in breast boost treatment planning: a prospective clinical study. Int J Radiat Oncol Biol Phys 2000 0.80
66 Actions of goldfish neuropeptide Y on the secretion of growth hormone and gonadotropin-II in female goldfish. Gen Comp Endocrinol 1993 0.79
67 A novel truncated apolipoprotein B (apo B55) in a patient with familial hypobetalipoproteinemia and atypical retinitis pigmentosa. Clin Genet 1992 0.79
68 Apolipoprotein E phenotype and lipoprotein(a) in familial hypercholesterolaemia: implication for lipoprotein(a) metabolism. Clin Investig 1994 0.79
69 Four DNA polymorphisms in the LDL receptor gene: their genetic relationship and use in the study of variation at the LDL receptor locus. J Med Genet 1988 0.79
70 Follow-up of recommendations for hostel care: some determinants of waiting times. Aust Health Rev 1993 0.78
71 The effects of imagery and sensory detection distractors on different measures of pain: how does distraction work? Br J Clin Psychol 1998 0.78
72 Resolution, by DNA probes, of uncertain diagnosis of inheritance of hypercholesterolaemia. Lancet 1988 0.78
73 Control of plasma fibrinogen levels. Baillieres Clin Haematol 1989 0.78
74 Elevated levels of factor VII activity in the postprandial state: effect of the factor VII Arg-Gln polymorphism. Thromb Haemost 1994 0.78
75 Genetic determinants of arterial thrombosis. Baillieres Clin Haematol 1994 0.77
76 Dietary intake and gene variation influence the response of plasma lipids to dietary intervention. Genet Epidemiol 1992 0.77
77 Fibrinolytic proteins and progression of coronary artery disease in relation to gemfibrozil therapy. Thromb Haemost 2000 0.77
78 Genetic determination of coagulation factor VIIc levels among healthy middle-aged women. Thromb Haemost 1995 0.77
79 RFLP studies in different ethnic groups. Atherosclerosis 1989 0.77
80 A study of familial hypercholesterolaemia in Iceland using RFLPs. J Med Genet 1989 0.77
81 The 16th annual meeting of the European Lipoprotein Club. Arterioscler Thromb 1994 0.77
82 European workshop on LDL receptor defects. European Working Group on Familial Hypercholesterolaemia. Clin Investig 1994 0.77
83 A variation in the apolipoprotein C-III gene is associated with an increased number of circulating VLDL and IDL particles in familial combined hyperlipidemia. J Lipid Res 1997 0.77
84 RFLPs of the LDL-receptor gene: their use in the diagnosis of FH and in evaluation of different levels of gene expression on normal subjects. Eur J Epidemiol 1992 0.77
85 The translation of mouse globin mRNA from which the polyadenylic acid sequence has been removed in a reinitiating protein synthesis system. Biochem Biophys Res Commun 1974 0.76
86 Is genotype or phenotype the better tool for investigating the role of ACE in human cardiovascular disease? Eur Heart J 2002 0.76
87 Relationship between calcaneal quantitative ultrasound and hip dual energy X-ray absorptiometry in young healthy men. Osteoporos Int 2012 0.76
88 Association of DNA-haplotypes in the human LDL-receptor gene with normal serum cholesterol levels. Clin Genet 1990 0.75
89 Vascular disease: the next target for local molecular therapeutics. BMJ 1994 0.75
90 An AvaII polymorphism in the haptoglobin alpha gene (HPA). Nucleic Acids Res 1989 0.75
91 Gene analysis and its role in predicting susceptibility to disease. Bioessays 1985 0.75
92 The 15th annual meeting of the European Lipoprotein Club. Arterioscler Thromb 1993 0.75
93 PCR-based method to create a specific mutation as a reference for oligomelting. Clin Chem 1991 0.75
94 Genetic tests for familial hypercholesterolemia. Nat Biotechnol 1996 0.75
95 Influences on choice of infant feeding methods. Ir Med J 1975 0.75
96 Three new polymorphisms of the ApoAI-CIII-AIV gene cluster. Mol Cell Probes 1994 0.75
97 Recombinant DNA technology and low-density lipoprotein receptor defects. Biochem Soc Trans 1987 0.75
98 The implications of genetic variation in human pathology. Biochem Soc Symp 1984 0.75
99 Prothrombin activation is increased among asymptomatic carriers of the prothrombin G20210A and factor V Arg506Gln mutations. Thromb Haemost 2000 0.75
100 The 19th annual meeting of the European Lipoprotein Club. Arterioscler Thromb Vasc Biol 1997 0.75
101 Effect of factor VII genotype on response to warfarin treatment. Thromb Haemost 1995 0.75
102 Oncogene products and other diagnostic markers in human breast cancer patients. Treatment effects and their significance. Ann N Y Acad Sci 1996 0.75
103 Needs assessment crucial to success of chapter offerings. AORN J 1979 0.75
104 The usefulness of three biallelic restriction fragment length polymorphisms versus a polymorphic dinucleotide tandem repeat polymorphism at the low-density-lipoprotein receptor gene locus for diagnosis of familial hypercholesterolemia. Dis Markers 1997 0.75
105 Dietary fat intake and plasma factor VII antigen concentration. Thromb Haemost 1995 0.75
106 Construction and partial characterization of a human liver cDNA library. Biomed Biochim Acta 1985 0.75
107 The hazards of smoking. Cent Afr J Med 1982 0.75
108 Prodromal cutaneous vasculitis in myelodysplastic syndromes. Br J Haematol 1990 0.75
109 Substoichiometric determination of traces of palladium by radioactive isotope-dilution analysis. Talanta 1971 0.75
110 The 13th annual meeting of the European Lipoprotein Club. Arterioscler Thromb 1991 0.75
111 An investigation of the diethyldithio-carbamates of palladium, including the determination of their stability constants. Talanta 1969 0.75
112 Substoichiometric determination of traces of palladium by neutron-activation analysis. Talanta 1970 0.75
113 DNA polymorphisms and the apolipoprotein B gene. Lancet 1986 0.75
114 First International Workshop on Familial Defective apo B-100, Munich, November 1991. Clin Investig 1992 0.75
115 A postulated phylogenetic tree for the human apolipoprotein B gene: unpredicted haplotypes are associated with elevated apo B levels. Biochim Biophys Acta 1993 0.75