Published in Circ Res on August 10, 1998
Regulation of blood pressure and salt homeostasis by endothelin. Physiol Rev (2011) 2.22
Vascular endothelin receptor type B: structure, function and dysregulation in vascular disease. Biochem Pharmacol (2012) 1.25
Mechanisms of fibrinogen-induced microvascular dysfunction during cardiovascular disease. Acta Physiol (Oxf) (2009) 1.18
Regulation of the endothelin system by shear stress in human endothelial cells. J Physiol (2000) 1.18
Increased endothelial exocytosis and generation of endothelin-1 contributes to constriction of aged arteries. Circ Res (2010) 1.13
Physiology of endothelin and the kidney. Compr Physiol (2011) 1.08
Endothelin-converting enzyme 1 promotes re-sensitization of neurokinin 1 receptor-dependent neurogenic inflammation. Br J Pharmacol (2009) 1.02
Secretory pathways in endothelin synthesis. Br J Pharmacol (1999) 0.98
Fibrinogen-induced endothelin-1 production from endothelial cells. Am J Physiol Cell Physiol (2009) 0.97
Regulation of cellular communication by signaling microdomains in the blood vessel wall. Pharmacol Rev (2014) 0.90
Immature endothelial cells initiate endothelin-mediated constriction of newborn arteries. J Physiol (2016) 0.89
Differential exocytosis from human endothelial cells evoked by high intracellular Ca(2+) concentration. J Physiol (2002) 0.86
Endothelin@25 - new agonists, antagonists, inhibitors and emerging research frontiers: IUPHAR Review 12. Br J Pharmacol (2014) 0.85
Potential of endothelin-1 and vasopressin antagonists for the treatment of congestive heart failure. Heart Fail Rev (2010) 0.84
Localization of alpha 1,3-fucosyltransferase VI in Weibel-Palade bodies of human endothelial cells. Proc Natl Acad Sci U S A (2000) 0.81
Clearance of cerebral Aβ in Alzheimer's disease: reassessing the role of microglia and monocytes. Cell Mol Life Sci (2017) 0.79
The endothelin B (ETB) receptor agonist IRL 1620 is highly vasoconstrictive in two syngeneic rat tumour lines: potential for selective tumour blood flow modification. Br J Cancer (2005) 0.78
Regulation of sodium transport in the proximal tubule by endothelin. Contrib Nephrol (2011) 0.75
Sphingosine-1-phosphate receptor 3 mediates sphingosine-1-phosphate induced release of weibel-palade bodies from endothelial cells. PLoS One (2014) 0.75
Imaging atherosclerotic plaque inflammation with [18F]-fluorodeoxyglucose positron emission tomography. Circulation (2002) 4.43
Nesprins: a novel family of spectrin-repeat-containing proteins that localize to the nuclear membrane in multiple tissues. J Cell Sci (2001) 3.24
Enhanced peroxynitrite formation is associated with vascular aging. J Exp Med (2000) 3.09
Onset of maternal arterial blood flow and placental oxidative stress. A possible factor in human early pregnancy failure. Am J Pathol (2000) 2.72
Apoptosis regulates human vascular calcification in vitro: evidence for initiation of vascular calcification by apoptotic bodies. Circ Res (2000) 2.50
The Concise Guide to PHARMACOLOGY 2013/14: overview. Br J Pharmacol (2013) 2.48
Amphiphysin is necessary for organization of the excitation-contraction coupling machinery of muscles, but not for synaptic vesicle endocytosis in Drosophila. Genes Dev (2001) 2.35
Bcl-2 complexed with Beclin-1 maintains full anti-apoptotic function. Oncogene (2009) 2.23
Orphan-receptor ligand human urotensin II: receptor localization in human tissues and comparison of vasoconstrictor responses with endothelin-1. Br J Pharmacol (2000) 1.78
Evidence that the death of macrophage foam cells contributes to the lipid core of atheroma. Atherosclerosis (1995) 1.70
Characterization and localization of endothelin receptor subtypes in the human atrioventricular conducting system and myocardium. Circ Res (1993) 1.56
In vitro ischemia-reperfusion injury in term human placenta as a model for oxidative stress in pathological pregnancies. Am J Pathol (2001) 1.54
Effect of anti-tumor necrosis factor alpha antibodies on histopathology of primary Salmonella infections. Infect Immun (1995) 1.48
ETA receptor-mediated constrictor responses to endothelin peptides in human blood vessels in vitro. Br J Pharmacol (1995) 1.48
In vitro osteoblast response to ferritic stainless steel fiber networks for magneto-active layers on implants. J Biomed Mater Res A (2012) 1.42
[(125)I]-(Pyr(1))Apelin-13 is a novel radioligand for localizing the APJ orphan receptor in human and rat tissues with evidence for a vasoconstrictor role in man. Br J Pharmacol (2001) 1.40
Post-translational modifications regulate matrix Gla protein function: importance for inhibition of vascular smooth muscle cell calcification. J Thromb Haemost (2007) 1.38
Chemokine receptor CCR5: from AIDS to atherosclerosis. Br J Pharmacol (2011) 1.29
Expression of tumor necrosis factor receptors in normal kidney and rejecting renal transplants. Lab Invest (2001) 1.25
Hydroxyapatite nano and microparticles: correlation of particle properties with cytotoxicity and biostability. Biomaterials (2009) 1.24
Novel ligands BQ123 and BQ3020 characterize endothelin receptor subtypes ETA and ETB in human kidney. Kidney Int (1993) 1.22
Calcification of human vascular cells in vitro is correlated with high levels of matrix Gla protein and low levels of osteopontin expression. Arterioscler Thromb Vasc Biol (1998) 1.18
Foam cell apoptosis and the development of the lipid core of human atherosclerosis. J Pathol (1996) 1.18
Characterization of two new ETB selective radioligands, [125I]-BQ3020 and [125I]-[Ala1,3,11,15]ET-1 in human heart. Br J Pharmacol (1992) 1.17
Effects of an ET1-receptor antagonist, FR139317, on regional haemodynamic responses to endothelin-1 and [Ala11,15]Ac-endothelin-1 (6-21) in conscious rats. Br J Pharmacol (1994) 1.15
Susceptibility of human placental syncytiotrophoblastic mitochondria to oxygen-mediated damage in relation to gestational age. J Clin Endocrinol Metab (1998) 1.14
Endothelin-1 mRNA is widely expressed in porcine and human tissues. J Clin Invest (1990) 1.13
[125I-His(9)]-ghrelin, a novel radioligand for localizing GHS orphan receptors in human and rat tissue: up-regulation of receptors with athersclerosis. Br J Pharmacol (2001) 1.11
Kisspeptins: a multifunctional peptide system with a role in reproduction, cancer and the cardiovascular system. Br J Pharmacol (2007) 1.11
Depressor and regionally-selective vasodilator effects of human and rat urotensin II in conscious rats. Br J Pharmacol (2001) 1.10
Distribution of P2X(1) and P2X(3) receptors in the rat and human urinary bladder. Pharmacology (2001) 1.10
Application of environmental scanning electron microscopy to determine biological surface structure. J Microsc (2009) 1.08
Apoptosis in human monocyte-macrophages exposed to oxidized low density lipoprotein. J Pathol (1996) 1.08
The role of apoptosis in the initiation of vascular calcification. Z Kardiol (2001) 1.08
Progressive formation of inclusions in the striatum and hippocampus of mice transgenic for the human Huntington's disease mutation. J Neurocytol (2000) 1.06
Acetylated low-density lipoprotein stimulates human vascular smooth muscle cell calcification by promoting osteoblastic differentiation and inhibiting phagocytosis. Circulation (2002) 1.06
Endothelin peptide and receptors in human atherosclerotic coronary artery and aorta. Circ Res (1996) 1.04
Comparison of in vivo dissolution processes in hydroxyapatite and silicon-substituted hydroxyapatite bioceramics. Biomaterials (2003) 1.04
Vasoconstrictor endothelin receptors characterized in human renal artery and vein in vitro. Br J Pharmacol (1994) 1.01
Effect of in vivo fetal infusion of dexamethasone at 0.75 GA on fetal ovine resistance artery responses to ET-1. Am J Physiol Regul Integr Comp Physiol (2001) 1.00
Presence of messenger ribonucleic acid for endothelin-1, endothelin-2, and endothelin-3 in human endometrium and a change in the ratio of ETA and ETB receptor subtype across the menstrual cycle. J Clin Endocrinol Metab (1992) 1.00
Secretory pathways in endothelin synthesis. Br J Pharmacol (1999) 0.98
Changes in intracellular electrolyte concentrations during apoptosis induced by UV irradiation of human myeloblastic cells. Am J Physiol Cell Physiol (2005) 0.97
Changes in vimentin in human macrophages during apoptosis induced by oxidised low density lipoprotein. Atherosclerosis (2001) 0.96
Calcium waves induced by hypertonic solutions in intact frog skeletal muscle fibres. J Physiol (2001) 0.95
Apoptosis in the early human placental bed and its discrimination from necrosis using the in-situ DNA ligation technique. Hum Reprod (1998) 0.95
Anatomical localization and pharmacological activity of mature endothelins and their precursors in human vascular tissue. J Hypertens (1992) 0.95
Evidence using immunoelectron microscopy for regulated and constitutive pathways in the transport and release of endothelin. J Cardiovasc Pharmacol (1998) 0.95
Thromboxane receptor density is increased in human cardiovascular disease with evidence for inhibition at therapeutic concentrations by the AT(1) receptor antagonist losartan. Br J Pharmacol (2001) 0.93
Evaluation of translocator protein quantification as a tool for characterising macrophage burden in human carotid atherosclerosis. Atherosclerosis (2009) 0.93
Emerging pharmacology and physiology of neuromedin U and the structurally related peptide neuromedin S. Br J Pharmacol (2009) 0.93
Comparison of the vasoconstrictor effects of rizatriptan and sumatriptan in human isolated cranial arteries: immunohistological demonstration of the involvement of 5-HT1B-receptors. Br J Clin Pharmacol (1998) 0.93
Endothelin receptors in human coronary artery and aorta. Br J Pharmacol (1996) 0.92
Identification and characterization of a newly recognized population of high-Na+, low-K+, low-density sickle and normal red cells. Proc Natl Acad Sci U S A (2000) 0.92
Normal conduction of surface action potentials in detubulated amphibian skeletal muscle fibres. J Physiol (2001) 0.91
Differentiation of the myocardial rudiment of mouse embryos: an ultrastructural study including freeze-fracture replication. J Anat (1986) 0.91
The tubular vacuolation process in amphibian skeletal muscle. J Muscle Res Cell Motil (1998) 0.91
Endothelin converting enzyme (ECE) activity in human vascular smooth muscle. Br J Pharmacol (1997) 0.90
Changes in concentration, localization and activity of catalase within the human placenta during early gestation. Placenta (1998) 0.90
Secretion of endothelin-1 and endothelin-3 by human cultured vascular smooth muscle cells. Br J Pharmacol (1995) 0.89
Characterization of the endothelin receptor selective agonist, BQ3020 and antagonists BQ123, FR139317, BQ788, 50235, Ro462005 and bosentan in the heart. Br J Pharmacol (1996) 0.89
Endothelin receptor subtypes and their functional relevance in human small coronary arteries. Br J Pharmacol (1998) 0.89
Long freeze-drying times are not necessary during the preparation of thin sections for X-ray microanalysis. J Microsc (2000) 0.89
Physiological antagonism of endothelin-1 in human conductance and resistance coronary artery. Br J Pharmacol (2001) 0.89
Immunogold-labeled L-type calcium channels are clustered in the surface plasma membrane overlying junctional sarcoplasmic reticulum in guinea-pig myocytes-implications for excitation-contraction coupling in cardiac muscle. J Mol Cell Cardiol (2000) 0.89
The increase in human plasma immunoreactive endothelin but not big endothelin-1 or its C-terminal fragment induced by systemic administration of the endothelin antagonist TAK-044. Br J Pharmacol (1996) 0.89
The presence of apoptotic cells in human atherosclerotic lesions. Am J Pathol (1997) 0.88
Alternatively spliced mRNAs for human endothelin-2 and their tissue distribution. Biochem Biophys Res Commun (1993) 0.88
Evidence for intracellular endothelin-converting enzyme-2 expression in cultured human vascular endothelial cells. Circ Res (1999) 0.88
A reappraisal of the contrasting morphological appearances of villous cytotrophoblast cells during early human pregnancy; evidence for both apoptosis and primary necrosis. Placenta (2003) 0.88
Endothelial cell-specific ETB receptor knockout: autoradiographic and histological characterisation and crucial role in the clearance of endothelin-1. Can J Physiol Pharmacol (2010) 0.88
Capillary surface area is reduced and tissue thickness from capillaries to myocytes is increased in the left ventricle of streptozotocin-diabetic rats. Diabetologia (1995) 0.88
Endothelin receptor antagonism in patients with chronic heart failure. Cardiovasc Res (2000) 0.87
A quantitative 'in-situ' hybridization method using computer-assisted image analysis. Validation and measurement of atrial-natriuretic-factor mRNA in the rat heart. Biochem J (1989) 0.87
Blockade and reversal of endothelin-induced constriction in pial arteries from human brain. Stroke (1999) 0.87
The influence of cell contact on the division of mouse 8-cell blastomeres. Development (1988) 0.87
Immunoelectron microscopical localization of human papillomavirus type 16 L1 and E4 proteins in cervical keratinocytes cultured in vivo. J Invest Dermatol (1993) 0.87
Characterization of endothelin isoforms in human heart: endothelin-2 demonstrated. J Cardiovasc Pharmacol (1993) 0.87
Nitric oxide-mediated modulation of the endothelin-1 signalling pathway in the human cardiovascular system. Br J Pharmacol (2001) 0.87
Fibroblast growth factor-1 improves the survival and regeneration of rat vagal preganglionic neurones following axon injury. Neurosci Lett (1999) 0.87
Selectivity of [125I]-PD151242 for human, rat and porcine endothelin ETA receptors in the heart. Br J Pharmacol (1995) 0.86
Failure of BQ123, a more potent antagonist of sarafotoxin 6b than of endothelin-1, to distinguish between these agonists in binding experiments. Br J Pharmacol (1996) 0.86
Vasoconstrictor activity of novel endothelin peptide, ET-1(1 - 31), in human mammary and coronary arteries in vitro. Br J Pharmacol (2001) 0.86
Affinity and selectivity of PD156707, a novel nonpeptide endothelin antagonist, for human ET(A) and ET(B) receptors. J Pharmacol Exp Ther (1997) 0.86
Simple modification of a commercial scanning laser microscope to incorporate dark-field imaging. J Microsc (1996) 0.86
Macrophage death and the role of apoptosis in human atherosclerosis. J Hematother Stem Cell Res (2001) 0.85
Expression of endothelin peptides and mRNA in the human heart. Clin Sci (Lond) (1996) 0.85
Endothelin ETA receptor expression in human cerebrovascular smooth muscle cells. Br J Pharmacol (1995) 0.85
Discovery of recently adopted orphan receptors for apelin, urotensin II, and ghrelin identified using novel radioligands and functional role in the human cardiovascular system. Can J Physiol Pharmacol (2002) 0.85
Characterization of the binding of endothelin ETB selective ligands in human and rat heart. Br J Pharmacol (1996) 0.85
Endothelin@25 - new agonists, antagonists, inhibitors and emerging research frontiers: IUPHAR Review 12. Br J Pharmacol (2014) 0.85
Localization of endothelin receptors in human uterus throughout the menstrual cycle. Mol Hum Reprod (1996) 0.84
Endothelin expression in the uterus. J Steroid Biochem Mol Biol (1995) 0.84
Endothelin receptor expression and pharmacology in human saphenous vein graft. Br J Pharmacol (1999) 0.84
Quantification of mRNA in human tissue using fluorescent nested reverse-transcriptase polymerase chain reaction. Anal Biochem (1994) 0.84
Morphology of presumptive rapidly adapting receptors in the rat bronchus. J Anat (1990) 0.84
Epidermal growth factor in human endometrium: proliferative effects in culture and immunocytochemical localization in normal and endometriotic tissues. Hum Reprod (1991) 0.84
Localization of endothelin peptides in human kidney. Kidney Int (1996) 0.84
Propofol preserves the viability of isolated rat hepatocyte suspensions under an oxidant stress. Anesth Analg (1998) 0.83