Mitochondrial dysfunction in neurodegenerative disorders.

Mitochondrial disease in superoxide dismutase 2 mutant mice. Proc Natl Acad Sci U S A (1999) 2.91

Mitochondrial dysfunction associated with increased oxidative stress and α-synuclein accumulation in PARK2 iPSC-derived neurons and postmortem brain tissue. Mol Brain (2012) 2.18

Mechanisms underlying caloric restriction and lifespan regulation: implications for vascular aging. Circ Res (2008) 1.75

Human deafness dystonia syndrome is a mitochondrial disease. Proc Natl Acad Sci U S A (1999) 1.53

Postmitotic neurons develop a p21-dependent senescence-like phenotype driven by a DNA damage response. Aging Cell (2012) 1.35

Selective determination of mitochondrial chelatable iron in viable cells with a new fluorescent sensor. Biochem J (2002) 1.16

Mitochondrial gene therapy augments mitochondrial physiology in a Parkinson's disease cell model. Hum Gene Ther (2009) 1.14

Retinitis pigmentosa and progressive sensorineural hearing loss caused by a C12258A mutation in the mitochondrial MTTS2 gene. Am J Hum Genet (1999) 1.13

Estrogen actions on mitochondria--physiological and pathological implications. Mol Cell Endocrinol (2008) 1.11

Mechanisms of the interaction of nitroxyl with mitochondria. Biochem J (2004) 1.07

Long-term supplementation with resveratrol alleviates oxidative stress but does not attenuate sarcopenia in aged mice. J Gerontol A Biol Sci Med Sci (2011) 1.06

Blood oxygenation level-dependent (BOLD)-based techniques for the quantification of brain hemodynamic and metabolic properties - theoretical models and experimental approaches. NMR Biomed (2012) 1.03

The structure of the yeast NADH dehydrogenase (Ndi1) reveals overlapping binding sites for water- and lipid-soluble substrates. Proc Natl Acad Sci U S A (2012) 1.02

Melatonin in Alzheimer's disease and other neurodegenerative disorders. Behav Brain Funct (2006) 1.01

Molecular mechanisms of West Nile virus pathogenesis in brain cell. Emerg Infect Dis (2005) 1.01

Using 'omics' to define pathogenesis and biomarkers of Parkinson's disease. Expert Rev Neurother (2010) 1.01

Association of mitochondrial antioxidant enzymes with mitochondrial DNA as integral nucleoid constituents. FASEB J (2009) 1.00

Oxidative stress and cerebral endothelial cells: regulation of the blood-brain-barrier and antioxidant based interventions. Biochim Biophys Acta (2011) 0.98

Transglutaminase activity is present in highly purified nonsynaptosomal mouse brain and liver mitochondria. Biochemistry (2005) 0.98

Quantitative PCR-based measurement of nuclear and mitochondrial DNA damage and repair in mammalian cells. Methods Mol Biol (2014) 0.95

Mitochondrial medicine for neurodegenerative diseases. Int J Biochem Cell Biol (2010) 0.93

Gastrointestinal dysfunction in a Parkinson's disease rat model and the changes of dopaminergic, nitric oxidergic, and cholinergic neurotransmitters in myenteric plexus. J Mol Neurosci (2011) 0.86

Ciclopirox protects mitochondria from hydrogen peroxide toxicity. Br J Pharmacol (2005) 0.86

A role for a novel protein, nucleolin, in Parkinson's disease. Neurosci Lett (2009) 0.85

Reactivation of protein aggregates by mortalin and Tid1--the human mitochondrial Hsp70 chaperone system. Cell Stress Chaperones (2011) 0.85

Enhanced ROS generation mediated by Alzheimer's disease presenilin regulation of InsP3R Ca2+ signaling. Antioxid Redox Signal (2010) 0.84

Cerebellar Ataxia. Curr Treat Options Neurol (2000) 0.83

Echinacoside Protects against 6-Hydroxydopamine-Induced Mitochondrial Dysfunction and Inflammatory Responses in PC12 Cells via Reducing ROS Production. Evid Based Complement Alternat Med (2015) 0.81

Mitochondrial function in human neuroblastoma cells is up-regulated and protected by NQO1, a plasma membrane redox enzyme. PLoS One (2013) 0.80

Optimization strategies for evaluation of brain hemodynamic parameters with qBOLD technique. Magn Reson Med (2012) 0.80

Neuroproteomics as a promising tool in Parkinson's disease research. J Neural Transm (Vienna) (2008) 0.79

Separation of cellular and BOLD contributions to T2* signal relaxation. Magn Reson Med (2015) 0.78

Characterization of mitochondrial function in cells with impaired cystic fibrosis transmembrane conductance regulator (CFTR) function. J Bioenerg Biomembr (2016) 0.75